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김문범 ( Moon Bum Kim ),김범준 ( Beom Joon Kim ),서영준 ( Young Joon Seo ),이양원 ( Yang Won Lee ),이애영 ( Ai Young Lee ),김규한 ( Kyu Han Kim ),김명남 ( Myeung Nam Kim ),김진우 ( Jin Woo Kim ),노영석 ( Young Suck Ro ),박영민 ( Y 대한피부과학회 2009 대한피부과학회지 Vol.47 No.5
Background: Interplay of numerous constitutional and precipitating factors are involved in the development of atopic dermatitis (AD). Most of these etiologic factors are not controllable, but barrier dysfunction can be managed. Correction of barrier abnormalities has been accepted as a first-line therapy with effective anti-inflammatory therapy. Objective: We wished to establish standardized skin care guidelines for Korean patients who suffer from atopic dermatitis. Methods: The skin care guidelines were proposed by the Korean Atopic Dermatitis Association (KADA), with a particular emphasis for barrier dysfunction in AD from a review of more than 100 published studies and related documents in the clinical literature by a task force team (TFT) of the KADA. The TFT also evaluated the reliability of the studies based on scientific evidence and the size of the study populations. The TFT disregarded controversial findings and summarized all of the collected studies. Results: Skin care guidelines were proposed by the KADA, particularly for barrier dysfunction in AD. A warm bath for approximately 20 minutes was recommended once daily. Soap can be used two or three times per week and aggressive skin scrubbing should be avoided. A topical moisturizer should be applied at least twice a day. Immediate application of emollient is required after bathing. The donning of clothing made of cotton is recommended. Nails should be cut short to reduce skin damage caused by a skin scratch. Conclusion: Application of moisturizer immediately after appropriate bathing may be the most important treatment for skin care. A topical steroid should be used whenever AD develops. Nail care and proper clothing are also be helpful for the prevention of dermatitis aggravation. Proper ways to bathe, use of moisturizer and topical steroids and nail care and appropriate clothing were considered. (Korean J Dermatol 2009;47(5):531~538)
아토피피부염 환자에서 국소 피메크로리무스의 효과와 순응도에 관한 다기관 설문조사
김범준 ( Beom Joon Kim ),김명남 ( Myeung Nam Kim ),김규한 ( Kyu Han Kim ),김도원 ( Do Won Kim ),노영석 ( Young Suck Ro ),박천욱 ( Chun Wook Park ),이승철 ( Seung Chul Lee ),이애영 ( Ai Young Lee ),최지호 ( Jee Ho Choi ),이광훈 ( K 대한피부과학회 2008 대한피부과학회지 Vol.46 No.10
Background: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease that`s influenced by many genetic and environmental factors. Various treatment modalities are being applied for AD, including phototherapy, topical applicants and systemic agents. However, there has been no mass survey in Korea concerning the compliance of patients` to use their prescribed medication, which might influence the clinical efficacy of the physicians` treatment. Objective: The purpose of the present study is to evaluate the efficacy, safety and patient compliance with using topical pimecrolimus to treat AD. Methods: We reviewed the medical recordings, laboratory profiles, clinical severity scoring and photographs of AD patients at 9 general hospitals in Seoul and the local area of Korea. Interviews with the patients and a telephone survey were also done. Those patients who weren`t perscribed topical applicants or those who did not use topical pimecrolimus or steroid within 6 months were excluded from this study. Results: Topical pimecrolimus cream effectively controlled AD with a reduction of the EASI score from baseline 13.75 to 11.39 at 2 weeks and 4.46 at 10 weeks of topical pimecrolimus application. When topical pimecrolimus cream was applied for more than 12 months it significantly suppressed the recurrence and reactivation of AD (p<0.05). Although 22.6% of the patients complained of adverse effects, these were all transient and they did not evoke significant medical problems. Using topical pimecrolimus cream did not show significant adverse effects or complications. Conclusion: Topical pimecrolimus might well be an effective treatment modality for treating AD when patients show good compliance for applying the cream. (Korean J Dermatol 2008;46(10):1357∼1361)
이지현 ( Ji Hyun Lee ),김규한 ( Kyu Han Kim ),김명남 ( Myeung Nam Kim ),김진우 ( Jin Woo Kim ),노영석 ( Young Suck Ro ),박영립 ( Young Lip Park ),박천욱 ( Chun Wook Park ),이광훈 ( Kwang Hoon Lee ),이애영 ( Ai Young Lee ),조상현 ( 대한피부과학회 2006 대한피부과학회지 Vol.44 No.8
Background: Atopic dermatitis is a chronic, relapsing, inflammatory skin disease, with genetic and environmental background. Successful management of atopic dermatitis requires a multipronged approach. However, standardized guidelines for the management of Korean atopic dermatitis patients do not exist. Objective: This study was performed to provide a standardized treatment guideline for atopic dermatitis in Korea. Methods: On the basis of treatment guidelines proposed by the ADRG (Atopic Dermatitis Research Group), we consider the characteristic provocation factors reported in previous Korean cases and the new modalities which have recently been introduced. Results: Management should compromise of a disease-adapted treatment which combines adjuvant basic therapy, symptomatic relief and, if needed, anti-inflammatory treatment and the identification and avoidance of trigger factors. New therapies such as topical calcineurin inhibitors are also considered to be good alternatives for the long-term control of atopic dermatitis. Conclusion: The algorithm contained within the article was presented as the basis for a guideline of clinical practice that could be used to facilitate the treatment of atopic dermatitis at any stage in Korea. (Korean J Dermatol 2006;44(8):907~913)
아토피피부염 학회보고서: 한국인 아토피피부염의 진단기준에 대한 연구
박영립 ( Young Lip Park ),김형동 ( Hyung Dong Kim ),김규한 ( Kyu Han Kim ),김명남 ( Myeung Nam Kim ),김진우 ( Jin Wou Kim ),노영석 ( Young Suck Ro ),박천욱 ( Chun Wook Park ),이광훈 ( Kwang Hoon Lee ),이애영 ( Ai Young Lee ),조상 대한피부과학회 2006 대한피부과학회지 Vol.44 No.6
Background: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease with genetic and environmental background. The diagnosis of AD depends on the clinical presentation and history because there are no objective laboratory tests. The criteria established by Hanifin and Rajka have become the standard for the clinical diagnosis of AD (Until now, we used conventional Hanifin and Rajka`s diagnostic guidelines). But diagnostic criteria for Korean have not been studied yet. Objective: The purpose of the present study was to establish the diagnostic criteria of Korean AD. Methods: We made out a draft for diagnostic criteria for Korean on the basis of the Hanifin and Rajka`s guidelines and published Korean journals. And we established the diagnostic criteria for Korean after collecting extensive opinions from dermatologic specialists in many university hospitals. Results: The major criteria of AD is similar to conventional diagnosic criteria, but three additional minor features(periauricular eczema, scalp scale, skin prick test reactivity) were significant for the diagnosis of AD in Korean patients. The other eleven minor features of the conventional minor diagnostic features were also significant. Conclusion: We established Korean diagnostic criteria for AD. Our result suggest that ethnic backgrounds influence the phenotype of AD and that additional three features need to be included in the Korean diagnostic criteria. Continued refinement of these guidelines will facilitate diagnosis in specific ethnic populations and in specific subgroups of patients. (Korean J Dermatol 2006;44(6):659~663)
원전용 디지털 인디케이터의 검증 규정 EPRI TR-106439에 관한 고찰
배창호(Chang-Ho Bae),이동희(Dong-Hee Lee),김규로(Kyu Ro Kim),장중순(Joong Soon Jang) 한국신뢰성학회 2014 신뢰성응용연구 Vol.14 No.4
Nuclear power plants may use commercial grade items if they can pass special tests or inspections, which is called Commercial Grade Item Dedication (CGID). Digital items, however, should follow EPRI TR-106439 to be applied to nuclear power plants. This paper explains the scheme and requirements of the EPRI TR-106439 and introduces some guidelines. Firstly, in order to clarify requirements of the EPRI TR-106439, code interpretation is performed. And through case study of digital indicator, limitations of EPRI TR-106439 are mentioned, and improvement direction is proposed.