http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
홍정희,마이크데이,Hong, J.H.,Day, Mike The Korean Society for Fluid Power and Constructio 2012 드라이브·컨트롤 Vol.13 No.4
This paper explains how eliminating contamination from the manufacturing processes will lead to better product quality and hence the need for reworking, a trouble free commissioning period and greatly improved production efficiency. All of these will reduce costs and energy usage. It will also ensure that the product is delivered to the customer in a condition that will ensure improved reliability and longer life, again reducing both energy and other operating costs. Correctly designing the contamination control measures will achieve and maintain the level of fluid cleanliness that is required by the end user. The filter is critical to cleanliness management and should be selected with the same degree of thought and consideration as for other major components. This paper explains the role that Cleanliness Management plays in the reducing the carbon footprint of systems and processes by making them perform more efficiently for longer periods. It also examines two differing ways of selecting filters to incorporate the features of newer designs, and shows how significant savings in the costs of ownership can be achieved using these approaches.
Monitoring of Cleanliness Level in Hydraulic Systems: Obtaining Reliable On-Line data
홍정희,마이크 데이,Hong, Jeong-Hee,Day, Mike The Korean Society for Fluid Power and Constructio 2012 드라이브·컨트롤 Vol.9 No.2
Monitoring of system cleanliness levels and counting of particulate contaminant are fundamental to achieving hydraulic system reliability as any departure from the specified cleanliness level is often a precursor to future failures. On-line monitoring of cleanliness levels has the advantage of giving data both very quickly and accurately as environmental influences are eliminated. In this way, corrective actions can be promptly implemented. Most on-line instruments are sensitive to system conditions to a greater or lesser extent, but Automatic Particle Counters (APCs) working on light extinction principles are especially sensitive to the presence of optical interfaces caused by such conditions as fluid mixtures, emulsions, free water and air bubbles. These conditions give erroneous data and can result in drawing incorrect conclusions, wasting maintenance time and ultimately, reduced user confidence in cleanliness monitoring. This paper describes such conditions and shows how the correct selection of the analysis technique can result in reliable cleanliness level data.
홍정희,이길호,최한용 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.9
Purpose: Curcumin is a nontoxic, chemopreventive agent possessing multifaceted functions. Our previous study showed that curcumin inhibits androgen receptor (AR) through modulation of Wnt/β-catenin signaling in LNCaP cells. Therefore, we investigated the in vivo effects of curcumin by using LNCaP xenografts. Materials and Methods: LNCaP cells were subcutaneously inoculated in Balb/c nude mice. When the tumor volume reached greater than 100 mm3, either curcumin (500 mg/kg body weight) or vehicle was administered through oral gavage three times weekly for 4 weeks. The expression of AR and intermediate products of Wnt/β-catenin were assessed. Results: Curcumin had an inhibitory effect on tumor growth during the early period, which was followed by a slow increase in growth over time. Tumor growth was delayed about 27% in the curcumin group. The mean prostate-specific antigen (PSA) doubling time in the curcumin group was approximately twice that in the untreated group. Curcumin significantly decreased AR expression at both the mRNA and protein level. The PSA levels tended to be reduced in the curcumin group. However, there were no significant changes in expression of Wnt/β-catenin pathway intermediates. Conclusions: This study revealed that curcumin initially interferes with prostate cancer growth by inhibiting AR activity and possibly by reducing PSA expression. Further research is needed to investigate the plausible mechanism of the antiandrogenic action of curcumin.