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      • KCI등재후보
      • KCI우수등재

        C-반응성단백과 가장 관련 있는 대사증후군 대사이상 항목

        중천,김범택,이득주,최현국,정현주,김광민 대한비만학회 2003 The Korean journal of obesity Vol.12 No.1

        연구배경: C-반응성단백 (이하 CRP)은 심혈관질환의 예후인자 및 독립적 위험인자이다. 대사증후군은 복부비만, 고혈압. 당대사이상 및, 지질대사이상과 같은 관상동맥질환 위험인자들이 동시에 나타나는 증후군을 말한다. 저자들은 18세 이상의 성인 남녀에서 CRP와 대사증후군 대사이상 항목과의 상관관계를 연구하였다. 방법: 2002년 4월부터 10월까지 일개 대학병원 건강증진센터에 내원한 수진자 2772명 중 염증성질환이 의심되는 577명을 제외한 총 2195명을 대상으로 하였다. 신체계측과 혈압측정, 혈액검사를 실시하였다. 통계적 분석은 남녀를 구분하여 대사증루군의 대사이상 항목의 군집성에 따른 CRP값에 대해 ANOVA 검정을 시행하였고, 각 대사이상 항목들과 연령을 독립변수로 하여 회귀분석을 실시하였다. 결과: CRP는 남성에서 0.10 (±0.004) mg/dL, 여성에서 0.08 (±0.003) mg/dL로 남성이 여성보다 유의하게 높았다(p<0.001). 남녀 모두에서 CRP가 대사증후군 군에서 대사증후군이 없는 군보다 유의하게 높았다. 대사증후군의 대사이상 항목 수가 증가할수록 CRP값이 증가하는 양상을 보였다(P for trend<0.001). 남녀 모두에서 허리둘레 (남성 R²=0.132, 여성 R²=0.166)가 가장 높은 설명력을 보였다. 결론: 18세 이상의 성인 남녀 모두에서 CRP는 대사증후군 대사이상 항목들과 유의한 상관관계를 보였다. 대사이상 항목중 허리둘레가 CRP 수치와 상관관계가 가장 높았다 Background: C-reactive protein has been known as an independent risk factor and prognostic factor for cardiovascular diseases. Metabolic syndrome is a sum of coronary risk factors such as abdominal obesity, elevated blood pressure, hypertension, glucose intolerance and abnormalities in lipid level. The previous studies showed limited relationships between CRP and the risk factors in metabolic syndrome. We investigated the relationships between CRP and the risk factors in metabolic syndrome in adult men and women over 18 years old. Methods: This study included 2772 people. 577 people of them found to have inflammatory disease excluded. The anthropometry and blood pressure were measured. High sensitive CRP, Lipid profiles, WBC, and ESR were assessed. Results: CRP in Men (0.10 (±0.004) mg/dL) was significantly higher than that in women (0.08 (±0.003) mg/dL)(P<0.001). In both genders, CRP was significantly higher in people who have metabolic syndrome than in people who don't. As the number of risk factors increased, CRP was significantly increased (P for trend < 0.001). Waist circumference showed the greatest correlation with CRP in men and women (men; R²=0.132, women; R²=0.166) Conclusion: CRP was correlated with risk factors in metabolic syndrome in men and women over 18 years old. Of the risk factors waist circumference was most correlated with CRP.

      • 미생물 Phytase의 첨가가 산란능력, 난각두께, 난각과 대퇴골의 강도 및 인의 배설량에 미치는 영향

        중천,김영길 東亞大學校 大學院 1998 大學院論文集 Vol.23 No.-

        Con-Wheat-Soy diets containing 100%(c) and 60% total phosphorus of NRC requirement were formulated for laying hens and 4 groups of 60 percent of total phosphorus diet were prepared without phytase(T1), with 100FTU(T2), 500FTU(T3), 1000FTU(T4) levels of phytase. A total of 180 laying hens(40wks old) were divided into 5 treatment with 3 replications. the effect of dietary treatments on egg production, egg weight, egg shell intensity and thickness and thickness and tibia broken strength were measured. 1.Egg production of hen on tratment C, T1,T2, was 85.2%, 87.6%, 86.9%, respectively without statistical differences but that of T3 was significantly higher(90.4%)(p<0.01) and T4 was significantly lower(80.7%). 2.Egg weight of T4 was similar to the control group, however, T1, t2, was significantly lower than other treatment group. 2.Egg shell thickness of control diet was thicker than other group and egg shell intensity of treatment T1, T2, T4 was significantly stronger(p<0.01). Howeverm older hens showed decreased intensity. 4.Strength of tibia broken of T1 treatment was significantly decreased than other treatment. Present result may conclude that with sufficient phytase in the diet inorganic phosphorus may not be needed and greater importance is the reduction of fecal phosphorus excreted into the environment when dietary phytase is used.

      • KCI우수등재

        미생물 Phytase 의 첨가가 산란계의 생산성에 미치는 영향

        중천,김인호,김영길 한국축산학회 1999 한국축산학회지 Vol.41 No.2

        An experiment was conducted to determine the effects of microbial phytase on production and phytate P utilization of laying hens. A total of 180 laying hens was used in the feeding Dial to determine the effects of different dietary phytase and P levels on egg production, egg weight, egg shell intensity and thickness and tibia breaking strength. Treatments were: 1) 100% of NRC requirement for total phosphorus(C), 2) 60% of NRC requirement for total phosphorus(T₁), 3) diet 2) with 100 FTU(T₂), 4) diet 2) with 500 FTU(T₃) and 5) diet 2) with 1,000 FTU(T₄). Egg productions of C, T₁ and T₂ were respectively 85.2, 87.6 and 86.9 % with no statistical differences but that of T₃was significantly(P$lt;0.05) higher(90.4%) and that of T₄ was lower(80.7%) than other treatments. Egg weight of T₄ was similar to the control group, but those of T₁ and T₂ were significantly(P$lt;0.05) lighter than the other treatments. Egg shell thickness of control was higher than those of other groups and egg shell intensities of T₁, T₂ and T₄ were significantly stronger(P $lt; 0.05) than those of other treatments. However as laying hen aged, egg shell intensity of each group has been weakened. Breaking strength of tibia of T₁ was significantly(P$lt;0.05) lower than other treatments.

      • KCI우수등재
      • KCI등재

        사료내 유기산제 및 항생제의 혼합첨가가 육성돈의 성장과 혈액성상에 미치는 영향

        이철호,조익환,중천,이성훈 한국유기농업학회 2009 韓國有機農業學會誌 Vol.17 No.2

        This study was carried out to evaluate the effect of replacing antibiotics by organic acid mixture on growth performances and blood metabolites in growing pigs. Twenty-five crossbred pigs (Large White×Landrace) at the age of 79 days were fed five different diets by supplementing organic acid mixture and chlortetracycline. The experimental diets were consisted of diets without antibiotics supple¬mentation (control), diets added 100㎎/㎏ of chlortetracycline to control diet (T1), diets added 100㎎/㎏ of chlortetracycline and 0.1 % of Acidomix®(comprising formic acid 25%, sorbic acid 10%, fumaric acid 10%) to control diet (T2), diets added 0.1% of Acidomix® to control diet (T3), and diets added 0.3% of Acidomix® to control diet (T4). The changes in feed conversion ratio, average daily gain and blood metabolites were investigated. Twenty-five pigs were allotted to five treatments with five replications of each and the experiment was conducted on the basis of complete randomized design for 6 weeks. Average daily gain was significantly (p<0.05) different between T4 and control diets. All treatments including diets added Acidomix® and chlortetracycline were slightly higher than control diets. The feed intakes did not show a significant difference between the control and other treatments, and did not give change in feed intake by the addition of Acidomix®. No differences on feed conversion ratio among treatments were observed but T4 and T3 treatments showed lower value than other treatments. The concentrations of blood urea nitrogen, total cholesterol and triglyceride were significantly (p<0.05) different among treatments, but their values were within the normal range representing that effects on blood profile by organic acid or antibiotics supplementation were not found. The results from this study indicated that adding chlortetracycline or organic acid mixtures to diets showed tendency to improve average daily gain and feed conversion ratio in growing pigs. These results showed that antibiotics could be replaced by organic acid mixture in growing pig diets, leading to stimulated growth and improved feed conversion ratio.

      • KCI우수등재

        초유 Gammaglobulin 의 효율적 분리방법

        김정우,중천,이민호 한국축산학회 1995 한국축산학회지 Vol.37 No.5

        This study was conducted to establish a effective isolation method for gammaglobulin(IgG) from bovine colostrum using formic acid and sodium sulfate- The level of IgG content of colostral whey treated with 0.3% formic acid(5.70 g/100 ㎖) was higher than those of 0.5% fomic acid(4.67 g/100 ㎖) and 0.7% formic acid treated groups(3.30 g/100 ㎖). And also its recovery rate of IgG content(95.9%) was higher than that of HCl treated whey(82.8%) (p$lt;0.05). 'Ihe isolation of IgG from 0.3% fomvc acid treated whey were carried out by the precipitation nnethods with sodium sulfate and ammonium sulfate. The sodium sulfate precipitation was found to be most effective method for the isolation of IgG from colostral whey an$lt;i its recovery rate of IgG(82.7%) was 25% higher than that of ammonium sulfate precipitation method (p$lt;0.05). The major composition of immunoglobulin classes of the concentrated isolate was IgG (100 ㎎/㎖) and small amount of IgA(dilution titre, 160) and IgM(dilution titre, 80) was also included. When the liquid form of gammaglobulin isolate conserved at cold temperature, the IgG content was not changed until 24weeks. Whereas, at room temperature, it decreased after 8 weeks of conservation.

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