Rapamycin Inhibits Expression of Elongation of Very-long-chain Fatty Acids 1 and Synthesis of Docosahexaenoic Acid in Bovine Mammary Epithelial Cells

Guo, Zhixin,Wang, Yanfeng,Feng, Xue,Bao, Chaogetu,He, Qiburi,Bao, Lili,Hao, Huifang,Wang, Zhigang Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.11

Mammalian target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth and metabolism and is sufficient to induce specific metabolic processes, including de novo lipid biosynthesis. Elongation of very-long-chain fatty acids 1 (ELOVL1) is a ubiquitously expressed gene and the product of which was thought to be associated with elongation of carbon (C) chain in fatty acids. In the present study, we examined the effects of rapamycin, a specific inhibitor of mTORC1, on ELOVL1 expression and docosahexaenoic acid (DHA, C22:6 n-3) synthesis in bovine mammary epithelial cells (BMECs). We found that rapamycin decreased the relative abundance of ELOVL1 mRNA, ELOVL1 expression and the level of DHA in a time-dependent manner. These data indicate that ELOVL1 expression and DHA synthesis are regulated by mTORC1 in BMECs.

A transmit diversity scheme for quantum communications

Guo, Ying,Chen, Zhigang,Song, Wei,Lee, Moon Ho Royal Swedish Academy of Sciences 2008 Physica scripta Vol.78 No.6

<P>This paper proposes a quantum two-branch transmit diversity scheme based on quantum maximal-ratio receiver combining (QMRRC) with one sender and two receivers. Exploiting two senders and one receiver, this scheme provides the same diversity order as that of one sender and two receivers. It can be generalized for two senders and <I>M</I> receivers to distribute quantum information with diversity order 2<I>M</I> for <I>M</I>⩾2. It has the advantage that it does not require any bandwidth expansion and feedback from the receiver to the sender, and its computation complexity is similar to QMRRC. As a consequence, it may transmit quantum information with more efficiency than the previous quantum key distribution (QKD) schemes.</P>

Achieving high mass loading of Na₃V₂(PO₄)₃@carbon on carbon cloth by constructing three-dimensional network between carbon fibers for ultralong cycle-life and ultrahigh rate sodium-ion batteries

Guo, Donglei,Qin, Jinwen,Yin, Zhigang,Bai, Jinman,Sun, Yang-Kook,Cao, Minhua Elsevier 2018 Nano energy Vol.45 No.-

<P><B>Abstract</B></P> <P>The mass loading of the active materials in most flexible electrodes is relatively low, which greatly impedes their practical application. Here, we report a facile strategy to achieve high mass loading of Na<SUB>3</SUB>V<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB>@carbon (NVP@C) supported on carbon cloth (NVP@C-CC) by a two-step coating followed by an annealing treatment and the resultant NVP@C-CC membrane can be used as a binder-free cathode for sodium ion batteries (SIBs). The NVP@C is not only uniformly anchored on the surface of carbon fibers of CC, but also filled between carbon fibers of CC in interconnected three-dimensional (3D) macroporous structure. It is because of the full use of the spaces between carbon fibers of CC that we achieve a high NVP@C mass loading. Thus-obtained NVP@C-CC exhibits excellent cyclability (82.0% capacity retention over 2000 cycles at 20C) and high rate capacity (96.8mAhg<SUP>−1</SUP> at 100C and 69.9mAhg<SUP>−1</SUP> at 200C) for sodium half cells and meanwhile the high mass loading of NVP@C on CC also endows the cell with fairly high energy and powder densities of 396Whkg<SUP>−1</SUP> and 97kWkg<SUP>−1</SUP>. Furthermore, it also presents superior cycling stability and rate performance when evaluated as full battery (NaTi<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB>@C as the anode) cathode. This study offers a new strategy for achieving high mass loading of the active materials on flexible supports in flexible energy storage devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A two-step coating strategy is used to prepare NVP@C-CC electrode with high mass loading. </LI> <LI> The high mass loading is attributed to the full use of the spaces among carbon fibers by contructing three-dimensinal network. </LI> <LI> The NVP@C-CC exhibits excellent cycling performance and superior rate capacity for both sodium half cells and full cells. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>The NVP@C-CC electrode with high mass loading was achieved by contructing three-dimensinal network among carbon fibers. The NVP@C-CC electrode exhibits excellent cycling performance and superior rate capacity for both sodium half cells and full cell cathode (NaTi<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB>@C as the anode). To further demonstrate its potential application, the as-prepared full cell can easy to power commercial red light-emitting diode bulb after being fully charged.</P> <P>[DISPLAY OMISSION]</P>

Free vibration analysis of continuous bridge under the vehicles

Guo-jin Tan,Wensheng Wang,Yubo Jiao,Zhigang Wei 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.61 No.3

Free vibration analysis for continuous bridge under any number of vehicles is conducted in this paper. Calculation strategy for natural frequency and mode shape is proposed based on Euler-Bernoulli beam theory and numerical assembly method. Firstly, a half-car planar model is adopted; equations of motion and displacement functions for bridge and vehicle are established, respectively. Secondly, the undermined coefficient matrices for wheels, vehicles, intermediate support, left-end support and right-end support are derived. Then, the numerical assembly technique for conventional finite element method is adopted to construct the overall matrix of coefficients for whole system. Finally, natural frequencies and corresponding mode shapes are determined based on iterative method and overall matrix solution. Numerical simulation is presented to verify the effectiveness of the proposed method. The results reveal that the solutions of present method are exact ones. Natural frequencies and associate modal shapes of continuous bridge under different conditions of vehicles are investigated. The influences of vehicle parameters on natural frequencies are also demonstrated.

Optimal adjustment process planning for precision machine tool assembly

Junkang Guo,Zhigang Liu,Jun Hong,Peng Liu 한국생산제조학회 2014 한국생산제조시스템학회 학술발표대회 논문집 Vol.2014 No.9(2)

Effects of Dietary Iodine and Selenium on the Activities of Blood Lymphocytes in Laying Hens

Song, Zhigang,Guo, Yuming,Yuan, Jianmin Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.5

The effect of dietary iodine and selenium supplementation, alone or in combination, on peripheral blood lymphocyte function was determined in laying hens. Eight-hundred-and-sixty-four New-Loman laying hens were randomly allotted into 12 dietary treatments with different inclusion levels of iodine (0, 0.1 and 0.2 mg/kg), selenium (0, 0.05, 0.1 and 0.2 mg/kg) or their combinations for 24 weeks. The lipopolysaccharide (LPS) stimulation index, concanavalin A (ConA) stimulation index, peroxide enzyme activity and phagocytosis to neutral red particles were tested. There were significant differences in LPS stimulation index, ConA stimulation index, peroxide enzyme activity and phagocytosis to neutral red particles in different iodine or selenium supplementation levels (p<0.05). The highest iodine and selenium supplementation both resulted in highest LPS-/ConA-stimulation indices (p<0.05). However, when iodine was lower than 0.2 mg/kg, the additional effect of different levels of selenium did not always result in significant differences in these indices. The results indicated that iodine and selenium may affect immunity in laying hens and, when the iodine level in the laying hen is lower than 0.2 mg/kg, a selenium allowance higher than 0.1 mg/kg may be necessary to improve immunity.

Experimental Study on Key Parameters of Bidirectional Cumulative Tensile Blasting with Coal-Containing Composite Roof

Pengfei Guo,Kengkeng Ye,Zhigang Tao,Hongda Liang,Yadi Yuan 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.5

To improve the effectiveness of the directional-predetermined crack blasting in the weak and alternate composite roof, this paper took the coal-containing composite roof of the 12201 working face of Halagou Coal Mine as the engineering background, and based on the technical principles of roof cutting pressure releasing gob-side entry retaining, comprehensive used of theoretical analysis, field experiments and other means, carried out in-depth research on the shaped energy blasting method and parameter design of the coal-containing composite roof. The results show: Through theoretical analysis, in the process of shaped energy blasting, the air column in the hole can reduce the peak blast pressure, which can effectively prevent the weak surrounding rock in the hole from being damaged in the non-cumulative direction and enhance the pre-splitting effect. During detonation at the bottom, the instantaneous pressure in the blast hole is lower than that of detonation at the top, and the action time of blast pressure is longer than detonation at the top. When the buried depth of the explosive (near the blast hole) is less than the critical depth, a "V"-shaped blasting funnel will be formed after the rock blasting, and the critical depth is proportional to the charge. Through field tests on the charge quantity and the length of the sealing mud, when the blast hole depth is 6m, the charge parameters of "3+2+0+1" have a better effect of energy-concentrating blasting, and the crack rate reaches 87%. Besides, field tests have shown that when shaped energy blasting is carried out on soft and hard rock formations, the stemming separation in the shaped energy tube at the interlayer position can ensure the directional pre-cracking effect of hard rock, while effectively avoiding damage to the weak rock formation in the non-cumulative direction.

Rapid and highly selective removal of lead in simulated wastewater of rare-earth industry using diglycolamic-acid functionalized magnetic chitosan adsorbents

Ruixi Bai,Yang Zhang,Zhigang Zhao,Qiuxia Liao,Peng Chen,Panpan Zhao,Wanghuan Guo,Fan Yang,Laichao Li 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.59 No.-

Rapid and highly selective magnetic core–shell adsorbents for Pb2+ removal from simulated wastewater of rare-earth industry were prepared by synthesizing chitosan-coated Fe3O4 (Fe@CS) beads and following chemical-grafting steps for the diglycolamic-acid group (DGA). The adsorbents had a highly selective ability for Pb2+ toward other metal ions, which attributed to the superior infinity between the DGA and Pb2+. The maximum adsorption capacity of Pb2+ was 70.57 mg/g. The R2 of the pseudo-second order kinetics was 0.99857, which indicated the adsorption process was controlled by chemical reactions. Moreover, diglycolamic-acid functionalized Fe@CS (Fe@CS-DGA) beads separated from water within 9 s under magnetic fields.

Influences of Pd precursors and preparation method on the catalytic performances of Pd-only close-coupled catalysts

Zengzan Zhu,Yun Guo,Yanglong Guo,Zhigang Zhang,Yanqin Wang,Guanzhong Lu 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.6

The properties and stabilities of Pd/Al2O3 close-coupled catalysts prepared with different methods and Pd precursors (PdCl2, Pd(NO3)2, and Pd(NH3)2(NO2)2) have been investigated, and characterized by N2adsorption at low temperature, H2 chemical adsorption, X-ray diffraction (XRD), H2 temperature programmed reduction (H2-TPR), transmission electron microscopy (TEM) and three-way catalytic activity testing. The results show that the catalyst prepared by a prefabricate method with Pd(NH3)2(NO2)2 precursor behaves higher catalytic activity and thermal stability for removing HC, CO and NOx, due to its higher BET surface area, higher Pd dispersion, smaller Pd particle sizes. And the prefabricate method can lead to stronger interaction between the Pd active species and the support by means of a strong electrostatic attraction and ion/ligand-exchange between the Pd complexes and the support surface, which restrict the remotion and sintering of Pd active particles at high temperature. Therefore, a prefabricate method is more suited to preparing close-coupled catalysts than a traditional impregnation method.

A simple preparation method for rare-earth phosphate nano materials using an ionic liquid-driven supported liquid membrane system

Panpan Zhao,Fan Yang,Zhigang Zhao,Qiuxiao Liao,Yang Zhang,Peng Chen,Wanghuan Guo,Ruixi Bai 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.54 No.-

For the first time, our group has developed a novel, high-flux strategy for shape-controlled synthesis of rare earth nano-materials (CePO4) using ionic liquid(IL)-driven supported liquid membrane (HVHP, DUPAPORE1) system. The system contains three phases including a supply phase of rare earth ions, a feed phase of phosphates, and ionic liquid-driven supporting liquid membrane phase. The imidazolium IL-driven supported liquid membrane is promising for nano-synthetic reaction of CePO4. The anion types of immersed imidazolium IL have a critical role in the formation rate of CePO4 nano-materials. Moreover, the adding SO4 2 anion or adjustment of pH in supply phase containing Ce(III) ions could control effectively the morphology of the CePO4 nano-materials. The result can be regarded as a good example, the IL:[C4mim][Tf2N] driven support liquid membrane systems can be used to prepare nano-wire and nano-sphere structures of CePO4 with high efficiency and flux. Besides, the IL-driven supported liquid membrane can be cycled many times by using the back flush activation method.