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Comparative Study of Peripheral Rim Fixation Using Jumbo Cup in Revisional Hip Arthroplasty
( Woo-lam Jo ),( Young-wook Lim ),( Jin-hyung Im ),( Seung-chan Kim ),( Soon-yong Kwon ),( Yong-sik Kim ) 대한고관절학회 2017 Hip and Pelvis Vol.29 No.1
Purpose: It is challenging procedure to revise acetabular component in acetabulum with severe bone defect or deformity. The jumbo cup is good option for revisional arthroplasty in large bone defect. The purpose of this study is to compare the prognosis of revisional total hip arthroplasty using jumbo cup with peripheral rim fixation and no rim fixation. Materials and Methods: We included the patients who had performed acetabular revisional total hip arthroplasty from January 2002 to March 2015 in our institute. Total of 51 hips (51 patients) were included. The mean follow up period was 51 months (range, 12 to 154 months) and mean age was 60.7 years (range, 30 to 81 years). We divided into two groups (peripheral rim fixation group and no rim fixation group) by anteroposterior and lateral plain radiograph. We compared survival rate, hip center change and clinical outcomes between two groups. Results: There were 37 patients in peripheral rim fixation group and 14 patients in no rim fixation group. There was one patient who had aseptic loosening necessary to re-revision in rim fixation group and 3 patients in no rim fixation group. And one patient had superficial infection in rim fixation group and one patient had periprosthetic fracture in no rim fixation group. Survival rate was higher in the peripheral rim fixation group (97.3%) than no rim fixation group (78.6%, P=0.028) Conclusion: Based on our findings, peripheral rim fixation might be recommended to improve short-term outcome after revision total hip arthroplasty using jumbo cup.
ARCO Consensus on the Pathogenesis of Non-traumatic Osteonecrosis of the Femoral Head
Quanjun Cui,Woo-Lam Jo,Kyung-Hoi Koo,Edward Y. Cheng,Wolf Drescher,Stuart B. Goodman,Yong-Chan Ha,Phillippe Hernigou,Lynne C. Jones,Shin-Yoon Kim,Kyu Sang Lee,Mel S. Lee,Yun Jong Lee,Michael A. Mont,N 대한의학회 2021 Journal of Korean medical science Vol.36 No.10
Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for the disease. Therefore, we provide an up-to-date consensus on the pathogenesis of non-traumatic ONFH.
Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment
Hines Jeremy T.,Jo Woo-Lam,Cui Quanjun,Mont Michael A.,Koo Kyung-Hoi,Cheng Edward Y.,Goodman Stuart B.,Ha Yong-Chan,Hernigou Phillippe,Jones Lynne C.,Kim Shin-Yoon,Sakai Takashi,Sugano Nobuhiko,Yamamo 대한의학회 2021 Journal of Korean medical science Vol.36 No.24
Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more prevalent along with increasing use of corticosteroids for the adjuvant therapy of leukemia and other myelogenous diseases as well as management of organ transplantation. This review updated knowledge on the pathogenesis, classification criteria, staging system, and treatment of ONFH.
유종민 ( Jong Min Yoo ),김승수 ( Sung Soo Kim ),조우람 ( Woo Lam Jo ),권순용 ( Soon Yong Kwon ) 한국조직공학과 재생의학회 2015 조직공학과 재생의학 Vol.12 No.1s
We have recently demonstrated the slow release of growth factors from calcium phosphate cements (CPCs) incorporated with platelet concentrate (PC). In the present study, the cell compatibility of CPCs was evaluated by culturing human osteoblast-like cells Saos-2 (ATCC HTB85) to demonstrate the PC effect. CPCs were characterized using scanning electron microscopy (SEM), X-Ray diffraction (XRD) and energy-dispersive X-ray spectroscopy (EDS) and their mechanical properties were tested. The physical and chemical properties of CPCs were little affected by the PC incorporation within the experimented range. The cell proliferation, morphology and migration, measurement of alkaline phosphatase (ALP) levels, mRNA expression for osteopontin (OPG), osteocalcin (OC), glyceraldehyde phosphate dehydrogenase (GAPDH) were evaluated. Higher cell proliferation was performed but the cell migration was not affected by the addition of PC. Actin filaments, focal adhesion, and localized integrin were clearly visible. The PC addition increased ALP activity and expression of GAPDH, OC, and OPG mRNA.
Prevalence of Venous Thromboembolism after Immediate Screening in Hip Fracture Patients
Kim Yoon-Vin,Song Joo-Hyoun,Lim Young-Wook,Jo Woo-Lam,Ha Seung-Hun,Lee Kee-Haeng 대한고관절학회 2024 Hip and Pelvis Vol.36 No.1
Purpose: Venous thromboembolism (VTE) is a major complication for hip fracture patients, and may exist preoperatively. This study aimed to examine the prevalence of VTE after immediate screening in hip fracture patients. Materials and Methods: Hip fracture patients with an elevated level of D-dimer underwent screening for VTE using computed tomography (CT) angiography. Anticoagulation treatments were administered preoperatively to patients diagnosed with VTE, followed by administration of additional anticoagulation postoperatively. Medical records were reviewed to identify risk factors for preoperative VTE and determine the prognosis of the patients. Results: Among 524 hip fracture patients, 66 patients (12.6%) were diagnosed with VTE, including 42 patients with deep vein thrombosis (DVT), 17 patients with pulmonary thromboembolism (PTE), and 7 patients with both DVT and PTE. Of the patients with VTE, 68.2% were diagnosed within 24 hours of injury, and 33.3% of these patients had PTE. VTE patients showed a tendency toward being overweight (P<0.01) and not on anticoagulant medication (P=0.02) compared to patients without VTE. The risk of VTE was higher for femur shaft fractures (odds ratio [OR] 4.83, 95% confidence interval [CI] 2.18-10.69) and overweight patients (OR 2.12, 95% CI 1.17-3.85), and lower for patients who were previously on anticoagulants (OR 0.36, 95% CI 0.18-0.74). Patients with preoperatively diagnosed VTE were asymptomatic before and after surgery. Conclusion: Clinicians should be aware that VTE may be present within 24 hours of injury, and screening for VTE or prophylactic measures should be considered for high-risk patients. Fracture, Venous thromboembolism, Screening, Overweight, Anticoagulant
Diagnosis and Treatment of Inflammatory Joint Disease
( Yeesuk Kim ),( Hyun-cheol Oh ),( Jang Won Park ),( In-sung Kim ),( Jun-young Kim ),( Ki-choul Kim ),( Dong-sik Chae ),( Woo-lam Jo ),( Joo-hyoun Song ) 대한고관절학회 2017 Hip and Pelvis Vol.29 No.4
Arthritis damages the cartilage within joints, resulting in degenerative changes, including loss of function and joint instability. Ankylosing spondylitis (AS) is a chronic inflammatory condition affecting the spine and bone-to-tendon attachment area within the sacroiliac joint leading to back pain and progressive spinal stiffness. In the final stages, AS causes hyperkyphosis-a condition closely tied to the human leukocyte antigen-B27 gene. Rheumatoid arthritis is a chronic, systemic autoimmune disease characterized by the simultaneous inflammation of the synovium of multiple joints, leading to joint damage (e.g., destruction, deformation and disability). In the past, nonsteroidal anti-inflammatory drugs or conventional disease-modifying antirheumatic drug (DMARDs) have been used for the treatment of these autoimmune diseases, but biologic DMARDs have recently been introduced with excellent results. Gout is a chronic inflammatory disease that causes an alteration of joints resulting in severe pain. Specifically, gout is associated with an accumulation of uric acid within the body resulting from dysregulated purine metabolism, causing recurrent paroxysmal inflammation in the joints. Allopurinol and febuxostat are the primary treatment options for individuals with gout. It is necessary to have an accurate understanding of the pathogenesis, pathological ecology and treatment of AS, rheumatoid arthritis, and gouty arthritis, which are the representative diseases that may cause inflammatory arthritis.