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ARCO Consensus on the Pathogenesis of Non-traumatic Osteonecrosis of the Femoral Head
Quanjun Cui,Woo-Lam Jo,Kyung-Hoi Koo,Edward Y. Cheng,Wolf Drescher,Stuart B. Goodman,Yong-Chan Ha,Phillippe Hernigou,Lynne C. Jones,Shin-Yoon Kim,Kyu Sang Lee,Mel S. Lee,Yun Jong Lee,Michael A. Mont,N 대한의학회 2021 Journal of Korean medical science Vol.36 No.10
Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for the disease. Therefore, we provide an up-to-date consensus on the pathogenesis of non-traumatic ONFH.
Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment
Hines Jeremy T.,Jo Woo-Lam,Cui Quanjun,Mont Michael A.,Koo Kyung-Hoi,Cheng Edward Y.,Goodman Stuart B.,Ha Yong-Chan,Hernigou Phillippe,Jones Lynne C.,Kim Shin-Yoon,Sakai Takashi,Sugano Nobuhiko,Yamamo 대한의학회 2021 Journal of Korean medical science Vol.36 No.24
Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more prevalent along with increasing use of corticosteroids for the adjuvant therapy of leukemia and other myelogenous diseases as well as management of organ transplantation. This review updated knowledge on the pathogenesis, classification criteria, staging system, and treatment of ONFH.