Analysis of the Gastrointestinal Symptoms of Uninvestigated Dyspepsia and Irritable Bowel Syndrome

( Kazutoshi Hori ),( Takayuki Matsumoto ),( Hiroto Miwa ) 대한소화기기능성질환·운동학회 2009 Gut and Liver Vol.3 No.3

Background/Aims: Epidemiological studies suggest that there is a considerable overlap between functional dyspepsia (FD) and irritable bowel syndrome (IBS). The aim of this study was to examine concurrent gastrointestinal symptoms in FD and IBS. Methods: A total of 186 college students filled out a questionnaire regarding whether they had uninvestigated dyspepsia (UD, FD without endoscopic examination) and IBS based on Rome-II criteria. Gastrointestinal symptoms were measured using the Gastrointestinal Symptom Rating Scale (GSRS) questionnaire. Results: A total of 181 students (98 males, mean age 24.6 years) completed both questionnaires. The prevalence of UD, IBS, and UD+IBS overlap was 12 (6.7%), 40 (22.1%), and 8 (4.4%), respectively. A significant UD+IBS overlap was observed (66.7% IBS in UD, 20.0% UD in IBS). Reflux scores of GSRS in either UD or IBS were significantly greater than in those without. Gastroesophageal reflux disease (GERD), defined as weekly occurring moderate symptoms of heartburn and/or acid regurgitation and evaluated using the GSRS, was found in 16 (8.8%) of the subjects. The prevalence of IBS was significantly higher in GERD patients than in non-GERD patients (50.0% vs 19.4%). Conclusions: The considerable overlap not only between UD and IBS, but also between GERD and IBS, suggests the involvement of common pathophysiological disturbances in the two conditions. (Gut and Liver 2009;3:192-196)

Effect of empathy trait on attention to faces

Damee Choi,Takayuki Nishimura,Midori Motoi,Yuka Egashira,Riko Matsumoto,Shigeki Watanuki 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

To extend knowledge of relationship between empathy trait and attention to face, the present study aimed at investigating relationship between self-reported empathy trait and N170 elicited by five facial expressions (happy, angry, surprised, afraid, and sad). Twenty-two participants (12 males and 10 females) discriminated those five facial expressions from emotionally neutral faces under an oddball paradigm while event-related potentials (ERP) were recorded. The empathy trait of participants was measured using the Interpersonal Reactivity Index (IRI, Davis, 1980). The results revealed that participants with high IRI score showed more negative amplitude of N170 (140 to 200 ms after stimulus onset) than those with low IRI score at posterior temporal area in response to happy, angry, surprised, and afraid faces. The present study thus suggests that people with high empathy trait pay attention to faces more than those with low empathy, in very early stage of processing of face with happy, angry, surprised, and afraid expressions. Furthermore, this also indicates that empathy trait is related with attention processing of not only negative expressions (angry and afraid) but also positive (happy) and ambiguous expression (surprised).

Effect of Empathy Trait on Attention to Faces: Evidence from N170

( Damee Choi ),( Takayuki Nishimura ),( Midori Motoi ),( Yuka Egashira ),( Riko Matsumoto ),( Shigeki Watanuki ) 한국감성과학회 2014 춘계학술대회 Vol.2014 No.-

To extend knowledge of relationship between empathy trait and attention to face, the present study aimed at investigating relationship between self-reported empathy trait and N170 elicited by five facial expressions (happy, angry, surprised, afraid, and sad). Twenty-two participants (12 males and 10 females) discriminated those five facial expressions from emotionally neutral faces under an oddball paradigm while event-related potentials (ERP) were recorded. The empathy trait of participants was measured using the Interpersonal Reactivity Index (IRI, Davis, 1980). The results revealed that participants with high IRI score showed more negative amplitude of N170 (140 to 200 ms after stimulus onset) than those with low IRI score at posterior temporal area in response to happy, angry, surprised, and afraid faces. The present study thus suggests that people with high empathy trait pay attention to faces more than those with low empathy, in very early stage of processing of face with happy, angry, surprised, and afraid expressions. Furthermore, this also indicates that empathy trait is related with attention processing of not only negative expressions (angry and afraid) but also positive (happy) and ambiguous expression (surprised).

SUITABLE FLOW DEPTH AND VELOCITY FOR SPAWNING OF AYU, PLECOGLOSSUS ALTIVELIS

ONITSUKA KOUKI,NAGAYA TAKAYUKI,HIGASHINO MAKOTO,TAKAMI TOHRU,OTSUKA NORIHARU,AKIYAMA JUICHIRO,OZEKI HIROAKI,MATSUMOTO KAZUYA,SHIRAISHI YOSIKI 한국수자원학회 2005 한국수자원학회 학술대회 Vol.2005 No.1

Three-Phase PWM Inverter and Rectifier with Two-Switch Auxiliary Resonant DC Link Snubber-Assisted

Shinichiro Nagai,Shinji Sato,Takayuki Matsumoto 전력전자학회 2005 JOURNAL OF POWER ELECTRONICS Vol.5 No.3

In this paper, a new conceptual circuit configuration of a 3-phase voltage source, soft switching AC-DC-AC converter using an IGBT module, which has one ARCPL circuit and one ARDCL circuit, is presented. In actuality, the ARCPL circuit is applied in the 3-phase voltage source rectifier side, and the ARDCL circuit is in the inverter side. And more, each power semiconductor device has a novel clamp snubber circuit, which can save the power semiconductor device from voltage and current across each power device. The proposed soft switching circuits have only two active power semiconductor devices. These ARCPL and ARDCL circuits consist of fewer parts than the conventional soft switching circuit. Furthermore, the proposed 3-phase voltage source soft switching AC-DC-AC power conversion system needs no additional sensor for complete soft switching as compared with the conventional 3-phase voltage source AC-DC-AC power conversion system. In addition to this, these soft switching circuits operate only once in one sampling term. Therefore, the power conversion efficiency of the proposed AC-DC-AC converter system will get higher than a conventional soft switching converter system because of the reduced ARCPL and ARDCL circuit losses. The operation timing and terms for ARDCL and ARCPL circuits are calculated and controlled by the smoothing DC capacitor voltage and the output AC current. Using this control, the loss of the soft switching circuits are reduced owing to reduced resonant inductor current in ARCPL and ARDCL circuits as compared with the conventional controlled soft switching power conversion system. The operating performances of proposed soft switching AC-DC-AC converter treated here are evaluated on the basis of experimental results in a 50kVA setup in this paper. As a result of experiment on the 50kVA system, it was confirmed that the proposed circuit could reduce conduction noise below 10 MHz and improve the conversion efficiency from 88. 5% to 90.5%, when compared with the hard switching circuit.

Use of perioperative ureteral stent in abdominal aortic aneurysm with retroperitoneal fibrosis - A report of two cases -

Junya Kusaka,Shigekiyo Matsumoto,Satoshi Hagiwara,Hironori Koga,Takayuki Noguchi 대한마취통증의학회 2012 Korean Journal of Anesthesiology Vol.63 No.1

Retroperitoneal fibrosis is associated with fibroblast proliferation due to inflammatory changes in adipose/fibrous tissue. Given that aortic dilation in abdominal aortic aneurysm can cause compression of the ureter, abdominal aortic aneurysm complicated by retroperitoneal fibrosis is likely to result in urinary tract obstruction. Accordingly,close attention to changes in perioperative urine volume is warranted when operating on patients with abdominal aortic aneurysm complicated by retroperitoneal fibrosis. We have recently performed laparotomies on two cases of abdominal aortic aneurysm complicated by retroperitoneal fibrosis. In the first case, surgery was performed without the placement of a ureteral stent. The patient developed postrenal acute renal failure caused by postoperative urinary retention. In the second case, ureteral stent placement in advance enabled perioperative management without complications. The clinical course of these cases suggests that, in laparotomy with concomitant retroperitoneal fibrosis, preoperative ureteral stent placement can prevent postoperative complications in the renal and urinary systems.

Three-Phase PWM Inverter and Rectifier with Two-Switch Auxiliary Resonant DC Link Snubber-Assisted

Nagai Shinichiro,Sato Shinji,Matsumoto Takayuki The Korean Institute of Power Electronics 2005 JOURNAL OF POWER ELECTRONICS Vol.5 No.3

In this paper, a new conceptual circuit configuration of a 3-phase voltage source, soft switching AC-DC-AC converter using an IGBT module, which has one ARCPL circuit and one ARDCL circuit, is presented. In actuality, the ARCPL circuit is applied in the 3-phase voltage source rectifier side, and the ARDCL circuit is in the inverter side. And more, each power semiconductor device has a novel clamp snubber circuit, which can save the power semiconductor device from voltage and current across each power device. The proposed soft switching circuits have only two active power semiconductor devices. These ARCPL and ARDCL circuits consist of fewer parts than the conventional soft switching circuit. Furthermore, the proposed 3-phase voltage source soft switching AC-DC-AC power conversion system needs no additional sensor for complete soft switching as compared with the conventional 3-phase voltage source AC-DC-AC power conversion system. In addition to this, these soft switching circuits operate only once in one sampling term. Therefore, the power conversion efficiency of the proposed AC-DC-AC converter system will get higher than a conventional soft switching converter system because of the reduced ARCPL and ARDCL circuit losses. The operation timing and terms for ARDCL and ARCPL circuits are calculated and controlled by the smoothing DC capacitor voltage and the output AC current. Using this control, the loss of the soft switching circuits are reduced owing to reduced resonant inductor current in ARCPL and ARDCL circuits as compared with the conventional controlled soft switching power conversion system. The operating performances of proposed soft switching AC-DC-AC converter treated here are evaluated on the basis of experimental results in a 50kVA setup in this paper. As a result of experiment on the 50kVA system, it was confirmed that the proposed circuit could reduce conduction noise below 10 MHz and improve the conversion efficiency from 88. 5% to 90.5%, when compared with the hard switching circuit.

Development of Wheeled Inverted Pendulum Type Personal Mobility with Pedal

Seonghee Jeong,Yuji Masuda,Yutaka Hiroi,Takayuki Takahashi,Osamu Matsumoto 제어로봇시스템학회 2012 제어로봇시스템학회 국제학술대회 논문집 Vol.2012 No.10

In this paper, the mechanism and basic driving function of a wheeled inverted pendulum-type personal mobility with a pedal (Wi-PMP) are described. The mobility consists of a wheeled inverted pendulum-type mobile platform and a leg rowing mechanism, and thus it can be driven by a rider’s leg rowing motion. Moreover, to retain the merits of pivot turning of a parallel two-wheeled mobility, a differential gear box and a one-way clutch are installed between the pedal and the wheel shafts. It is designed such that a rider can ground his feet while sitting on the saddle. In addition, the Wi-PMP is compact and light-weight, and thus it can be driven and parked in a narrow space. Through experiments using three types of driving mode(motor driving, pedal driving, and assist driving), it was confirmed that mobility can realize all driving modes and pivot turning while keeping the feet of the rider on the pedals.

Original Article : Adsorptive Granulocyte/Monocyte Apheresis for the Maintenance of Remission in Patients with Ulcerative Colitis: A Prospective Randomized, Double Blind, Sham-Controlled Clinical Trial

( Ken Fukunaga ),( Yoko Yokoyama ),( Koji Kamokozuru ),( Kazuko Nagase ),( Shiro Nakamura ),( Hiroto Miwa ),( Takayuki Matsumoto ) The Editorial Office of Gut and Liver 2012 Gut and Liver Vol.6 No.4

Background/Aims: Weekly granulocyte/monocyte adsorption (GMA) to deplete elevated and activated leucocytes should serve as a non-pharmacological intervention to induce remission in patients with ulcerative colitis (UC). This trial assessed the efficacy of monthly GMA as a maintenance therapy to suppress UC relapse. Methods: Thirty-three corticosteroid refractory patients with active UC received 10 weekly GMA sessions as a remission induction therapy. They were then randomized to receive one GMA session every 4 weeks (True, n=11), extracorporeal circulation without the GMA column every 4 weeks (Sham, n=11), or no additional intervention (Control, n=11). The primary endpoint was the rate of avoiding relapse (AR) over 48 weeks. Results: At week 48, the AR rates in the True, Sham, and Control groups were 40.0%, 9.1%, and 18.2%, respectively. All patients were steroid- free, but no statistically significant difference was seen among the three arms. However, in patients who could taper their prednisolone dose to <20 mg/day during the remission induction therapy, the AR in the True group was better than in the Sham (p<0.03) or Control (p<0.05) groups. Conclusions: Monthly GMA may potentially prevent UC relapse in patients who have achieved remission through weekly GMA, especially in patients on <20 mg/day PSL at the start of the maintenance therapy. (Gut Liver 2012;6:427-433)

Immunohistochemical differentiation between chronic enteropathy associated with SLCO2A1 gene and other inflammatory bowel diseases

Satoko Yamaguchi,Shunichi Yanai,Shotaro Nakamura,Keisuke Kawasaki,Makoto Eizuka,Noriyuki Uesugi,Tamotsu Sugai,Junji Umeno,Motohiro Esaki,Takayuki Matsumoto 대한장연구학회 2018 Intestinal Research Vol.16 No.3

Background/Aims: We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) as causative variants of chronic enteropathy associated with SLCO2A1 (CEAS). The aim of this study was to evaluate SLCO2A1 protein expression in the intestinal tissues of patients with CEAS, intestinal Behçet’s disease (BD), simple ulcer (SU), and Crohn’s disease (CD). Methods: Immunohistochemical staining using a polyclonal anti-SLCO2A1 antibody was performed on the resected intestinal specimens from 13 cases of CD, 9 cases of intestinal BD/SU, and 3 cases of CEAS. The extent of SLCO2A1 expression was determined by counting positively-staining vascular endothelial cells and scored as 0 (no cells), 1 (1%−30% cells), 2 (31%−60%), or 3 (>60%). The intensity of SLCO2A1 expression was scored either as 0 (negative), 1 (intermediate), or 2 (strong). The extent score and intensity score were summed for the final score of 0, 2, 3, 4, or 5. Results: SLCO2A1 protein expression was observed in 1 of 3 cases of CEAS (33%), all 13 cases of CD (100%), and all 9 cases of BD/SU (100%). The mean final expression scores of CEAS, CD, and BD/SU were 1.6 (range, 0−5), 4.8 (range, 4−5), and 4.3 (range, 4−5), respectively. The final expression score in CEAS was significantly lower than in CD (P=0.03). Conclusions: Immunohistochemical staining of the SLCO2A1 protein is considered useful to distinguish CEAS from other inflammatory bowel diseases.