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Park, Tong-Soo,Sohn, Ki-Soo,Choi, Sang-Don 慶北大學校 物理化學硏究所 1982 硏究論文集 Vol.3 No.-
The temperature dependence of cyclotron resonance lineshape (CRLS) for a quasi 2-dimensional piezoelectric polaron system is obtained on the basis of the linear response theory and the proper connected diagram method. The CRLS is Lorentzian in the moderate quantum limit. The linewidth increases with the temperature, which is very similar in feature to the case of deformation potential polaron system.
Sang-Hwa Yi,Don-Ha Hwang,Wee Sang Park 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.6
For on-line partial discharge (PD) monitoring of rotating machines, a novel sensor is proposed, which can be installed on the power lead inside the terminal box of the machine. The sensor has been designed to have high capacitance, and minimal reflection of measured pulses. As a sensitivity of the sensor, transfer impedance Zt has been measured and compared to conventional coupler-type sensors. A simple method is presented for measuring Zt of coupler sensors, using a vector network analyzer and a practical lead-cable of rotating machine. Through this method, it became possible to measure the Zt of coupler sensors including the installation environment of them. The Zt of the proposed sensor is higher than that of same sized other conventional couplers at frequencies between 30 and 92 MHz. Another sensitivity test has been performed using a PD calibrator as a test pulse source. The proposed sensor has higher measured peak voltage than the conventional coupler type sensors when the same charges were input.
Recurrent Erlotinib-Induced Interstitial Lung Disease on Non-Small Cell Lung Cancer
Park, Sang Don,Kim, Areum,Park, Jin-Seok,Shin, Chun Ho,Nam, Hae Sung,Kim, Lucia,Cho, Jae Wha,Ryu, Jeong Sun,Kwak, Seung Min The Korean Academy of Tuberculosis and Respiratory 2009 Tuberculosis and Respiratory Diseases Vol.67 No.5
Erlotinib ($Tarceva^{(R)}$) has been considered to be a new, promising oral chemotherapy agent for local advanced or metastatic non-small cell lung cancer (NSCLC). Erlotinib is regarded as relatively safe, but interstitial lung disease (ILD) related to erlotinib has been reported on an infrequent basis in Asia. We report an histologically confirmed case of recurrent erlotinib-induced ILD. Although, the patient was highly responsive to the first erlotinib treatment, the therapy was discontinued due to erlotinib-induced ILD. After intravenous high dose methylpredinisolone treatment, ILD was improved rapidly by radiologic studies, but the particular lung cancer re-emerged. We restarted the patient erlotinib on low-dose oral methylpredinisolone, resulting in a recurrence of erlotinib-induced ILD. Our case suggests that re-administration of erlotinib should be performed on a limited basis in patients that have developed ILD on previous use, even if a therapeutic effect can be estimated.
Park, Hyoung Su,Kim, Don‐,Kyu,Lee, Sang Yi,Park, Ki‐,Hwan John Wiley Sons Ltd 2017 Journal of texture studies Vol.48 No.5
<P>Practical applicationsIn Korea, the aging population is rapidly increasing. According to recent surveys, a large number of elderly Koreans have reported chewing difficulties and many of them are in the state of under-nutrition. As aging progresses, multiple physiologic changes occur in mastication and swallowing functions. These changes may cause individuals to reduce their food intake or switch to soft food products. Therefore, the development of texture-modified food products for the elderly is needed and they should be developed based on the understandings of the physiology of mastication and swallowing according to different rheological properties of food products consumed in Korea, which are quite different from those of the western countries. In this study, we compared the differences of mastication and swallowing parameters between the young adults and the elderly depending on the varying hardness of rice food product.</P>
Antiplatelet activity and clinical outcomes on CYP3A4-metabolized statin in PCI
( Sung Woo Kwon ),( Jong-beom Shin ),( Jae-hyung Park ),( Sehwan Oh ),( Mi-hwa Park ),( Sang-ho Jeong ),( Sung-hee Shin ),( Seong-ill Woo ),( Sang-don Park ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Purpose: Statins primarily metabolized by cytochrome P450 3A4 (CYP3A4) reportedly reduce clopidogrel metabolism to active metabolite. Recent studies suggest that CYP 3A4-metabolized statins attenuate the anti-aggregatory effect of clopidogrel. We sought to assess the antiplatelet activity of a CYP 3A4 metabolized statin and its association with clinical outcomes duringdual antiplatelet therapy following percutaneous coronary intervention (PCI). Methods: Among 3,755 patients enrolled the HOST-ASSURE trial, 1,187 patients with both baseline and 1-month platelet reactivity unit (PRU) values assessed by VerifyNow P2Y12 assay were assigned to the CYP 3A4-metabolized statin group (n=725) or non-CYP 3A4-metabolized statin group (n=462) according to type of statins used. The co-primary outcome were the differences between baseline and 1-month follow-up of PRU value and the composite of cardiovascular death, recurrent MI, including stent thrombosis, any revascularization and cerebrovascular accident (CVA) during the follow-up period. We compared the outcomes between groups both in the propensity adjusted and matched cohorts. Results: Mean difference of PRU values was not significant in the CYP 3A4-metabolized statin group (mean difference: -4±84, p=0.367) and was significant in the non-CYP 3A4-metabolized statin group (mean difference: -12±69, p=0.006) both in the propensity scoreadjusted and matched cohorts. Patients with high PRU value at baseline, irrespective of the type of used statins, were associated with a significant reduction in mean difference of PRU values both in the propensity score adjusted (mean difference: -53.35, p<0.001) and matched cohort (mean difference: -41.57, p<0.001). The composite of clinical events did not differ between groups both in the propensity score adjusted (hazard ratio [HR] 0.962, 95% confidence interval [CI] 0.621-1.489, p=0.861) and matched (HR 0.902, 95% CI 0.554-1.468, p=0.678) cohorts. Conclusions: This study showed that a CYP 3A4-metabolized statin slightly reduces antiplatelet activity of clopidogrel during dual antiplatelet therapy but did not increase clinical events in patients following PCI.
Wavelength-switchable ns-pulsed active mode locking fiber laser for photoacoustic signal generation
Park, Sang Min,Kim, Gyeong Hun,Lee, Hwi Don,Kim, Chang-Seok Elsevier 2019 OPTICS AND LASER TECHNOLOGY Vol.115 No.-
<P><B>Abstract</B></P> <P>We present a novel design for a wavelength-switchable nanosecond-pulsed erbium-doped fiber laser that simultaneously achieves a repetition rate of the order of hundreds of kilohertz as well as pulse energies in the hundred-nanojoule range to fulfil the requirements of photoacoustic (PA) imaging applications. Instead of conventional Q-switching of a single-wavelength output, rapid switching among multi-wavelength outputs in the 1600 nm region can be performed by tuning acousto-optic modulation frequencies under low-order active mode-locking conditions. The pulse repetition rate of the laser can be tuned from 200 kHz to 1 MHz, depending on the mode-locking order. In order to verify the potential of our proposed design for use in real-time PA applications, we detected PA signals generated by an absorbing target using a PA signal detection system with our dual-wavelength laser outputs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We demonstrated a wavelength-switchable laser that does not rely on Q-switching. </LI> <LI> The laser can switch rapidly among multi-wavelength outputs in the 1600 nm region. </LI> <LI> Using mode locking, the pulse repetition rate can be tuned from 200 kHz to 1 MHz. </LI> <LI> The laser is suitable for real-time photoacoustic sensing and imaging applications. </LI> <LI> Future extension is possible for detection of lipids or oxy-/deoxy-hemoglobin. </LI> </UL> </P>
Park Do Hyeon,Lee Eunyoung,Jung Jongtak,Kang Chang Kyung,Song Kyoung-Ho,Choe Pyoeng Gyun,Park Wan Beom,Bang Ji Hwan,Kim Eu Suk,Kim Hong Bin,Park Sang-Won,Kim Nam Joong,Oh Myoung-don 대한의학회 2022 Journal of Korean medical science Vol.37 No.16
Background: The relationship between changes in anxiety levels and personal protective equipment (PPE) use is yet to be evaluated. The present study assessed this relationship among healthcare workers (HCWs) involved in the care of patients with coronavirus disease 2019 (COVID-19). Methods: An online survey was conducted in a municipal hospital with 195 nationally designated negative pressure isolation units in Korea. Anxiety level was measured using the self-rating anxiety scale (SAS), and changes in anxiety levels were assessed based on the time when COVID-19 vaccine was introduced in March 2021 in Korea. Monthly PPE usage between June 2020 and May 2021 was investigated. Results: The mean SAS score (33.25 ± 5.97) was within normal range and was lower than those reported in previous studies conducted before COVID-19 vaccination became available. Among the 93 HCWs who participated, 64 (68.8%) answered that their fear of contracting COVID-19 decreased after vaccination. The number of coveralls used per patient decreased from 33.6 to 0. However, a demand for more PPE than necessary was observed in situations where HCWs were exposed to body fluids and secretions (n = 38, 40.9%). Excessive demand for PPE was not related to age, working experience, or SAS score. Conclusion: Anxiety in HCWs exposed to COVID-19 was lower than it was during the early period of the pandemic, and the period before vaccination was introduced. The number of coveralls used per patient also decreased although an excessive demand for PPE was observed.
AgIn dendrite catalysts for electrochemical reduction of CO<sub>2</sub> to CO
Park, Hyanjoo,Choi, Jihui,Kim, Hoyoung,Hwang, Eunkyoung,Ha, Don-Hyung,Ahn, Sang Hyun,Kim, Soo-Kil Elsevier 2017 Applied catalysis. B, Environmental Vol.219 No.-
<P><B>Abstract</B></P> <P>In this work, the catalytic activities of electrodeposited Ag and AgIn bimetallic dendrites have been explored for electrochemical reduction of CO<SUB>2</SUB> to CO. In the case of Ag dendrites, the Ag crystal structure was found to be affected by the deposition potential and showed different Ag(220)/Ag(111) ratios. The Faradaic efficiencies to produce CO increased as this ratio increased, whereas the partial current densities for CO generation were found to have a stronger relationship with the roughness of the Ag catalyst. The electrodeposition of AgIn was carried out to investigate the effect of addition of In and its content on the catalytic performance, while maintaining the dendritic morphology. The crystal structures of AgIn dendrites were found to vary with the amount of added In, demonstrating a linear increase in the ratio Ag(220)/Ag(111) with increasing In content and a positive impact on the production of CO. Furthermore, there was a competition between the suppression of the hydrogen evolution reaction (HER) vs. the decrement in the amount of active Ag with increasing addition of In. It was found that these complementary effects resulted in a superior CO Faradaic efficiency of AgIn dendrites with a volcano shaped curve based on the In content. The complementary effect on the catalytic activity could be extended to the various reduction potentials, indicating the significant effect of HER suppression at highly negative reduction potentials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> AgIn dendrite are electrodeposited for electrochemical reduction of CO<SUB>2</SUB> to CO. </LI> <LI> Morphology and composition and AgIn dendrites are controlled. </LI> <LI> Suppressed hydrogen evolution by In enables high CO Faradaic efficiency. </LI> <LI> Enhanced Ag(220)/Ag(111) ratio contributes to CO Faradaic efficiency. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>