http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Cyclooxygenase-2 Polymorphisms and Susceptibility to Colorectal Cancer: A Meta-Analysis
Jun Wang,Xufeng Guo,Jixiang Zhang,Jia Song,Mengyao Ji,Shijie Yu,Jing Wang,Zhuo Cao,Weiguo Dong 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.6
Purpose: Four polymorphisms, -765G>C, -1195G>A, 8473T>C, and Val511Ala, in the cyclooxygenase-2 (COX-2) gene were identified to be associated with colorectal cancer (CRC) risk. However, the results are inconsistent. The objective of this meta-analysis was to evaluate the association between these four polymorphisms and the risk of CRC. Materials and Methods: All eligible case-control studies published up to December 2012 on the association between the four polymorphisms of COX-2 and CRC risk were identified by searching PubMed and Web of Science. The CRC risk associated with the four polymorphisms of the COX-2 gene was estimated for each study by odds ratio (OR) together with its 95% confidence interval (CI), respectively. Results: A total of 15 case-control studies were included. Overall, no evidence has indicated that the -1195A allele, -765C allele, 8473C allele, and 511Ala allele are associated with susceptibility to CRC (-1195G>A: OR=1.11, 95% CI: 0.82-1.51, p=0.78; -765G>C: OR=1.08, 95% CI: 0.96-1.21, p=0.07; 8473T>C: OR=1.03, 95% CI: 0.89-1.18, p=0.91; Val511Ala:OR=0.71, 95% CI: 0.46-1.09, p=0.94). However, stratified analysis with ethnicity indicated that individuals with -765GC or GC/CC genotypes had an increased risk of CRC among Asian populations (GC vs. GG: OR=1.05, 95% CI: 0.87-1.28, p=0.03; GC+CC vs. GG: OR=1.08, 95% CI: 0.96-1.21, p=0.07). Conclusion: This meta-analysis indicated that -765G>C polymorphism was significantly associated with susceptibility to CRC in Asian populations.
The Properties of Planck Galactic Cold Clumps in the L1495 Dark Cloud
Tang, Mengyao,Liu, Tie,Qin, Sheng-Li,Kim, Kee-Tae,Wu, Yuefang,Tatematsu, Ken’ichi,Yuan, Jinghua,Wang, Ke,Parsons, Harriet,Koch, Patrick M.,Sanhueza, Patricio,Ward-Thompson, D.,Tó,th, L. Viktor,S American Astronomical Society 2018 The Astrophysical journal Vol.856 No.2
Shi, Shengbin,Wang, Hang,Uddin, Mohammad Afsar,Yang, Kun,Su, Mengyao,Bianchi, Luca,Chen, Peng,Cheng, Xing,Guo, Han,Zhang, Shiming,Woo, Han Young,Guo, Xugang American Chemical Society 2019 Chemistry of materials Vol.31 No.5
<P>A planar backbone conformation is essential for enabling polymer semiconductors with high charge carrier mobility in organic thin-film transistors. Benefiting from the smaller van der Waals radius of the O atom in furan (versus the S atom in thiophene), alkylated furan exerts a reduced steric hindrance on neighboring arene, and it was found that the head-to-head (HH)-linked 3,3′-dialkyl-2,2′-bifuran (<B>BFR</B>) can attain a high degree of backbone planarity. Hence, <B>BFR</B> should be a promising building block for constructing polymer semiconductors with a planar backbone conformation and hold distinctive advantages over a dialkylbithiophene-based analogue, which is typically highly twisted. The alkyl chains on the 3 and 3′ positions offer good solubility to the resulting polymers, which in combination with its planar backbone yields an improved molecular design window for developing high-performance polymer semiconductors, particularly those with a simple molecular structure and based on the acceptor co-unit without any solubilizing chains. When incorporated into polymer semiconductors, remarkably high hole and electron mobilities of 1.50 and 0.31 cm<SUP>2</SUP> V<SUP>-1</SUP> s<SUP>-1</SUP> are obtained for <B>BFR</B>-based polymers <B>FBFR-BO</B> and <B>CNBFR-C18</B> containing fluorinated and cyano-functionalized benzothiadiazole as the acceptor co-unit, respectively. Such mobilities are the highest values for HH-linked polymers and also among the best for furan-containing polymers. The results demonstrate that HH-linked dialkylbifuran is a highly promising building block for constructing organic and polymeric semiconductors, and this new approach by incorporating HH <B>BFR</B> offers several distinctive advantages for developing high-performance polymer semiconductors, including effective optoelectronic property tuning using a minimal number of aromatic rings, reduced structural complexity, facile material synthesis, good material solubility, and enriching the material library. In addition, the study offers important guidelines for future development of furan-based polymers and head-to-head linkage containing organic semiconductors.</P> [FIG OMISSION]</BR>
Jianxing Sun,Mengyao Ci,Guangda Xu,Rucheng Wang,Weibin Ni,Zongmei Xu,Shao-Jie Wang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.5
To increase the assembly construction efficiency of low-rise and multi-story buildings in rural areas, the precast shear wall for RC composite column confined uniform hollow panels was designed in this paper. The seismic performance and failure mechanism of the structure are studied by combining low cyclic load test with finite element and theoretical analysis. The study found that the connection between the components is safe. The structure has three progressive failure processes that are the interaction stage, composite column constrained dense column work stage and weak framework stage. The structure has good bearing and capacity of energy dissipation, and the ductility coefficient of the specimen is 2.89. In addition, the finite element model is established based on ABAQUS, and the damage evolution process of the structure is visually represented by the damage nephogram. In combination with test and simulation, calculation methods of shear capacity of the shear wall are established. The ratio of test value to calculated value in the interaction stage and weak framework stage is 1.14 and 1.06 respectively. The calculation method is reliable and has clear physical significance. The study can provide a reference for the application in low-rise and multi-story buildings.
Recent progress on photodynamic therapy and photothermal therapy
김희정,YANG MENGYAO,권나현,조문연,HAN JINGJING,Wang Rui,Qi Sujie,Li Haidong,Nguyen Van‐Nghia,Li Xingshu,Cheng Hong‐Bo,윤주영 대한화학회 2023 Bulletin of the Korean Chemical Society Vol.44 No.3
Noninvasive treatments for terminal cancer patients constitute a new trend in tumor treatment. Therefore, phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has attracted considerable interest. Light and a photosensitizer (PS) are employed in both treatment methods. For PDT, the PS generates reactive oxygen species (ROS) when exposed to light, whereas for PTT, the PS generates heat. In this regard, the systematic design of new PSs has become an active area of phototherapy research in an effort to solve the problems associated with conventional PSs. In the past decade, acti- vatable and heavy-atom-free PSs have become significant research areas. Therefore, we discuss our recent contributions to the PDT and PTT in this account.
Demand‐based charging strategy for wireless rechargeable sensor networks
Ying Dong,Yuhou Wang,Shiyuan Li,Mengyao Cui,Hao Wu 한국전자통신연구원 2019 ETRI Journal Vol.41 No.3
A wireless power transfer technique can solve the power capacity problem in wireless rechargeable sensor networks (WRSNs). The charging strategy is a widespread research problem. In this paper, we propose a demand‐based charging strategy (DBCS) for WRSNs. We improved the charging programming in four ways: clustering method, selecting to‐be‐charged nodes, charging path, and charging schedule. First, we proposed a multipoint improved K‐means (MIKmeans) clustering algorithm to balance the energy consumption, which can group nodes based on location, residual energy, and historical contribution. Second, the dynamic selection algorithm for charging nodes (DSACN) was proposed to select on‐demand charging nodes. Third, we designed simulated annealing based on performance and efficiency (SABPE) to optimize the charging path for a mobile charging vehicle (MCV) and reduce the charging time. Last, we proposed the DBCS to enhance the efficiency of the MCV. Simulations reveal that the strategy can achieve better performance in terms of reducing the charging path, thus increasing communication effectiveness and residual energy utility.
Yanyan Nie,Fangyi Li,Liming Wang,Jianfeng Li,Yanle Li,Mingshuai Sun,Mengyao Wang,Guoyan Li 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.1
As a kind of green energy, wind energy has become cost-competitive mainstream energy in the world. The gearbox is one of the most important and vulnerable components in the wind turbine (WT), which suffers a high failure rate and downtime. It is of great significance to the condition monitoring and fault diagnosis of the WT gearbox. However, in the multistage WT gearbox, the vibrations generated from different stages are coupled, which leads to a complex vibration spectral structure and brings difficulties in condition monitoring and fault diagnosis. Aiming to understand the vibration frequency features of multistage WT gearboxes, a novel phenomenological vibration model is established and the spectral structure is deduced by using the Fourier series analysis. In the vibration model, the phenomenon of inter-stage meshing frequency modulation (ISMFM) is considered, which is clearly proposed for the first time. The theoretical derivations are validated by both simulation and engineering tests using a 2.0 MW industrial WT gearbox. The results show that under healthy conditions, in addition to the meshing frequencies and their harmonics of each stage, there are also ISMFM sidebands in the vibration spectrum of the multistage WT gearbox, and the amplitude of the sidebands will change with the health status of the gearbox. The findings are not only applicable to the WT gearbox studied in this paper, but also to other similar multistage gearbox systems, which can provide a priori spectral structure for a multistage gear transmission system to assist its condition monitoring and fault diagnosis.