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Barros Mariana Silva,Silva Paula Fernanda Damasceno,Santana Márcia Luciana Carregosa,Bragança Rafaella Mariana Fontes,Faria-e-Silva André Luis 대한치과보존학회 2023 Restorative Dentistry & Endodontics Vol.48 No.1
Objectives This study aimed to evaluate the surrounding and underlying shades’ effect on the color adjustment potential (CAP) of a single-shade composite used in a thin layer. Materials and Methods Cylinder specimens (1.0 mm thick) were built with the Vittra APS Unique composite, surrounded (dual specimens) or not (simple specimens) by a control composite (shade A1, A2, or A3). Simple specimens were also built only with the control composites. Each specimen’s color was measured against white and black backgrounds or the simple control specimens with a spectrophotometer (CIELAB system). The whiteness index for dentistry (WID) and translucency parameters (TP00) were calculated for simple specimens. Differences (ΔE00) in color between the simple/dual specimens and the controls were calculated. The CAP was calculated based on the ratios between data from simple and dual specimens. Results The Vittra APS Unique composite showed higher WID and TP00 values than the controls. The highest values of ΔE00 were observed among simple specimens. The color measurements of Vittra APS Unique (simple or dual) against the control specimens presented the lowest color differences. Only surrounding the single-shade composite with a shaded composite barely impacted the ΔE00. The highest CAP values were obtained using a shaded composite under simple or dual specimens. Conclusions The CAP of Vittra APS Unique was strongly affected by the underlying shade, while surrounding this composite with a shaded one barely affected its color adjustment.
Mariana Nikolova,Gabriela Ambrozova,Maria Kratchanova,Petko Denev,Veselin Kussovski,Milan Ciz,Antonin Lojek 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.8
The current survey investigates the effect of four polysaccharides isolated from fresh leek or alcohol insoluble substances (AIS) of leek on the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) from phagocytes. The ability of the polysaccharides to activate serum complement was also investigated. Despite the lack of antioxidant activity, the pectic polysaccharides significantly decreased the production of ROS by human neutrophils. Polysaccharides isolated from AIS markedly activated RAW 264.7 macrophages for RNS production in a concentration-dependent manner. The Western blot analysis revealed that this effect was due to the stimulation of the inducible nitric oxide synthase protein expression of macrophages. The polysaccharides extracted from AIS with water showed the ability to fix serum complement, especially through the alternative pathway. It was found that the polysaccharide that has the highest complement-fixing effect is characterized by the highest content of uronic acids and the highest molecular weight.
Mariana Appel Hort,Elke Zuleika Schuldt,ˆ ngela Cristina Bet,Silvia DalBo,Jarbas Mota Siqueira,,Carla Ianssen,Fa´tima Abatepaulo,Heraldo Possolo de Souza,Beatriz Veleirinho,Marcelo Maraschin,Rosa Mari 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.10
Moderate wine intake (i.e., 1–2 glasses of wine a day) is associated with a reduced risk of morbidity and mortality from cardiovascular disease. The aim of this study was to evaluate the anti-atherosclerotic effects of a nonalcoholic ethyl acetate fraction (EAF) from a South Brazilian red wine obtained from Vitis labrusca grapes. Experiments were carried out on low-density lipoprotein (LDL) receptor knockout (LDLr−/−) mice, which were subjected to a hypercholesterolemic diet and treated with doses of EAF (3, 10, and 30 mg/kg) for 12 weeks. At the end of the treatment, the level of plasma lipids, the vascular reactivity, and the atherosclerotic lesions were evaluated. Our results demonstrated that the treatment with EAF at 3 mg/kg significantly decreased total cholesterol, triglycerides, and LDL plus very low-density lipoprotein levels compared with control hypercholesterolemic mice. The treatment of mice with EAF at 3 mg/kg also preserved the vasodilatation induced by acetylcholine on isolated thoracic aorta from hypercholesterolemic LDLr−/− mice. This result is in agreement with the degree of lipid deposit on arteries. Taken together, the results show for the first time that the lowest concentration of an EAF obtained from a red wine produced in southern Brazil significantly reduced the progression of atherosclerosis in mice.
Mariana TSANEVA 조선대학교 지식경영연구원 2013 기업과 혁신연구 Vol.6 No.2
A comparative study has been done in attempt to evaluate some of the major properties of weighted mixtures of distributions and their predictive ability for risk management purposes. The process of constructing weighted sums of normal distributions has been demonstrated starting from the properties of the most common distributions, continuing with problems that lead to combining individual distributions in mixtures, and finishing with analysis of the predictive ability of two different brands of mixtures: arithmetic and weighted sum of normal distributions. The models was applied to three sets of economic data for South Korea. The estimation of predictive ability in these cases was based on their discrimination ability. The results obtained after performing linear discriminant analysis show better accuracy (between 0.28% and 9.5%) of the weighted sums of normal distributions than the one of the arithmetic sums.
Continuous-Discontinuous Model for Ductile Fracture
Mariana R. R. Seabra,Jose M. A. Cesar de Sa 한국소성가공학회 2010 기타자료 Vol.2010 No.6
In this contribution, a continuum-dicontinuum model for ductile failure is presented. The degradation of material properties trough deformation is described by Continuum Damage Mechanics in a non-local integral formulation to avoid mesh dependence. In the final stage of failure, the damaged zone is replaced by a cohesive macro crack and subsequent traction-free macro crack for a more realistic representation of the phenomenon. The inclusion of the discontinuity surfaces is performed by the XFEM and Level Set Method and avoids the spurious damage growth typical of this class of models.
Modelling and Optimisation of Up-and Down-Milling Processes for a Representative Pocket Feature
Mariana Dotcheva,Krassimir Dotchev,Ivan Popov 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
This paper presents the specifics of the two types of end-milling, up- and down-milling, in the context of process planning of a finishing operation for machining complex pocket features. An optimisation mechanism is used for a pocket type of end-milling operation with the aim of comparing the results from up- and down-milling. Two sets of cutting conditions have been generated and analysed for each type of end-milling- one with constant parameters for the entire tool path, derived from the worst case of cutting (representing the usual process planning approach) and another set representing the optimised process. The predicted results were verified through experiments. The optimized cutting parameters, when machining the critical corner, demonstrate the important changes in magnitude and direction of the radial cutting-tool deviation and surface error.
Intradermal Tests for Diagnosis of Drug Allergy are not Affected by a Topical Anesthetic Patch
Mariana Couto,Diana Silva,Ana Ferreira,Josefina R. Cernadas 대한천식알레르기학회 2014 Allergy, Asthma & Immunology Research Vol.6 No.5
The use of topical anesthesia to perform intradermal tests (IDTs) for drug allergy diagnosis was never investigated. We aimed to determine the effectsof a topical anesthetic patch containing prilocaine-lidocaine on wheal size of IDT with drugs. Patients who had positive IDT as part of their investigationprocess of suspected drug hypersensitivity were selected. IDT were performed according to guidelines. Anesthetic patch (AP) wasplaced and the same prior positive IDT, as well as positive histamine skin prick test (SPT) and negative (saline IDT) controls, were performed in theanesthetized area. Patients with negative IDT were also included to check for false positives with AP. Increase in wheals after 20 minutes both withand without AP was recorded and compared. 45 IDT were performed (36 patients), of which 37 have been previously positive (14 antibiotics, 10 generalanesthetics, 6 non-steroidal anti-inflammatory drugs, 3 iodinated contrasts, 3 anti-Hi-histamines and 1 ranitidine). Mean histamine SPT sizewithout the AP was 4.7 mm [95%CI (4.4-5.1)], and 4.6 mm [95%CI (4.2-5.0)] with anesthesia. Mean wheal increase in IDT for drugs without the anesthesiawas 4.5 mm [95%CI (3.3-5.7)] and with anesthesia was 4.3 mm [95%CI (2.8-5.8)]. No statistical significant differences were observed betweenskin tests with or without AP for histamine SPT (P=0.089), IDT with saline (P=0.750), and IDT with drugs (P=0.995). None of the patientswith negative IDT showed positivity with the AP, or vice-versa. The use of an AP containing prilocaine-lidocaine does not interfere with IDT to diagnosedrug allergy, and no false positive tests were found.
Self-identity in Empathy Development
Mariana Hwang 한국기독교교육정보학회 2006 Journal of Christian education information tech Vol.0 No.10
This paper argues that empathic ability is one of the essential aspects of Christian maturity, and it is directly related to the person's understanding of self. Although several studies have suggested different methods and approaches to nurture empathic behaviors, empathy as part of the character of a person must stem from the inner self. Studies revealed that a person's either positive or negative behavior is motivated from the person's positive or negative self-concept. This is to say that possessing a clear and positive understanding of self is critical in empathy development. Two reasons explain why an individual's self-concept and the person's empathy development are closely related: First, positive behaviors are motivated from positive sense of self, whereas, negative or violent behaviors come from the person's negative sense of self. Second, a person cannot truly understand others unless he or she first clearly understands self. Factors that influence the construction of the self-concept are parents, object relations, cognitive development, social relations, and God-concept.