http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Kim, Il-Kyu,Kim, Byung-Seok,Koh, Choong-Hyun,Seok, Jae-Won,Park, Jun-Seok,Shin, Kwang-Soo,Bae, Eun-Ah,Lee, Ga-Eun,Jeon, Hyewon,Cho, Jaebeom,Jung, Yujin,Han, Daehee,Kwon, Byoung S,Lee, Ho-Young,Chung, Nature Publishing Group, a division of Macmillan P 2015 Nature medicine Vol.21 No.9
<P>T cell stimulation via glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR) elicits antitumor activity in various tumor models; however, the underlying mechanism of action remains unclear. Here we demonstrate a crucial role for interleukin (IL)-9 in antitumor immunity generated by the GITR agonistic antibody DTA-1. IL-4 receptor knockout (Il4ra(-/-)) mice, which have reduced expression of IL-9, were resistant to tumor growth inhibition by DTA-1. Notably, neutralization of IL-9 considerably impaired tumor rejection induced by DTA-1. In particular, DTA-1-induced IL-9 promoted tumor-specific cytotoxic T lymphocyte (CTL) responses by enhancing the function of dendritic cells in vivo. Furthermore, GITR signaling enhanced the differentiation of IL-9-producing CD4(+) T-helper (T(H)9) cells in a TNFR-associated factor 6 (TRAF6)- and NF-kappa B-dependent manner and inhibited the generation of induced regulatory T cells in vitro. Our findings demonstrate that GITR co-stimulation mediates antitumor immunity by promoting T(H)9 cell differentiation and enhancing CTL responses and thus provide a mechanism of action for GITR agonist-mediated cancer immunotherapies.</P>
Wang, Fan,Jeon, Jin-Han,Park, Sukho,Kee, Chang-Doo,Kim, Seong-Jun,Oh, Il-Kwon The Royal Society of Chemistry 2016 SOFT MATTER Vol.12 No.1
<P>Upcoming human-related applications such as soft wearable electronics, flexible haptic systems, and active bio-medical devices will require bio-friendly actuating materials. Here, we report a soft biomolecule actuator based on carboxylated bacterial cellulose (CBC), ionic liquid (IL), and poly (3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) electrodes. Soft and biocompatible polymer-IL composites were prepared via doping of CBC with ILs. The highly conductive PEDOT: PSS layers were deposited on both sides of the CBC-IL membranes by a dip-coating technique to yield a sandwiched actuator system. Ionic conductivity and ionic exchange capacity of the CBC membrane can be increased up to 22.8 times and 1.5 times compared with pristine bacterial cellulose (BC), respectively, resulting in 8 times large bending deformation than the pure BC actuators with metallic electrodes in an open air environment. The developed CBC-IL actuators show significant progress in the development of biocompatible and soft actuating materials with quick response, low operating voltage and comparatively large bending deformation.</P>
한동기,김권일 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.2
The purpose of this study was to analyze special teachers' recognition toward the goals of physical education in the elementary school for the students with mental retardation. The subjects of this study were 237 teachers in the elementary school for the students with mental retardation, located in Seoul, Kyong-Ki, and In-Chon. The results of this study were as follows: 1. The male teacher group showed a higher than female teacher group recognition level on the goals except for the goals of psychic equilibrium and spatial orientation. 2. There were differences in the goals of physiological efficiency, object manipulation, communication, group interaction and cultural involvement among the groups by career. 3. Teachers of lower grade(1~3) have a higher level of recognition than level of upper grade(4~6) on the goal of 6 areas except the goal of spatial orientation. 4. There were no differences in recognition level of the goals of the physical education between the teachers with physical education class responsible and without.
다운증후근 아동과 청소년의 슬관절 등속성 근력 특성 비교
한동기,김권일 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.1
This study was to provide fundamental information of muscle strength training, gait, and gross motor movement through comparing and analyzing low limb isokinetic torque of children and adolescents with Down syndrome. The subjects were 8 children with Down syndrome and 8 adolescents with Down syndrome. The peak torque, average power, and total work were measured with Cybex 770 at the speed 0f 60˚/sec and 180˚/sec. The data were analyzed by SPSS. The conclusions were drawn as follows; 1. The peak torque was decreased as angular velocity increasing. 2. Muscle strength was unequal between left and right knee joint. 3. Adolescents with Down syndrome were higher that children in the peak torque, average power, total work, and flexor/extensor ratio. Therefore, children and adolescents with Down syndrome had normal characteristics related with isokinetic strength. However, there are lots of possibilities of injury during activities because of the imbalance between left and right leg and low flexor/extensor ratio.
HFC-134a와 대체냉매 HFC-152a에 CF_3I를 혼합한 자동차냉매 특성
권일욱,박찬수,홍경한,문기선,최운수,서의경,윤갑식,이종인,하옥남 朝鮮大學校 機械技術硏究所 2002 機械技術硏究 Vol.5 No.1
These days, an attention of environment has been increasing all over the world. to prevent the green house effect and destruction of an ozone layer, an ozone destruction potential(ODP) be zero and a refrigerant for low global warming potential(GWP) is needed. HFC-134a, in which hydrogen is mixed instead of chlorine is a refrigerant used for automobile conditioners and its destruction potential is ecologically zero. However, it is not considered as a perfect substitutive refrigerant as its GWP is high. It is studied refrigerant mixtures in which HFC-134a, HFC-152a and CF_3I with low GWP and zero ODP are mixed by experimentally and concluded as follows; 1. with the variation of speed of compressor outside temperature and flow rate, the heat of evaporator and compressor and coefficient of performance was varied, and influenced the air conditioner. 2. The pressure of evaporator was decreased with increasing the speed of compressor and that of the refrigerant HFC-134a was higher 21% than that of azotrope refrigerant mixed with CF_3I. The overall capacity of condensor and evaporator was increased and HGC-134a was higher than azotrope refrigerant mixed with CF_3I 3. The capacity of evaporator with the refrigerant HFC-134a was higher 6% than azotrope refrigerant mixed with CF31 and the required power with zaotrope refrigerant mixed with CF_3I was higher 11% than that of HFC-134a. 4. The COP of the refrigerant FHC-134a was higher 31% in 1000RPM. when outside temperature was increased, COP was decreased. 5. Performance of HFC-134a is better than azotrope refrigerant mixed with CF_3I but prefered zaotrope refrigerant mixed with CF_3I considering the environment.
코쉬섬 1차 반복 형태의 마이크로스트립 패치 안테나에 관한 연구
김일권,유태훈,육종관,박한규 연세대학교 전파통신연구소 2001 電波通信論文誌 Vol.5 No.1
In this paper, the microstrip patch antenna applying the koch island fractal geometry is introduced in order to reduce the antenna patch size. By space-filling property of fractal geometry, the microstrip patch applying koch island has low frequency compared with square patch antenna. In the case of 1st order iteration patchs are investigated by simulator and experiment. Through this, it is found that as the fractal iteration factor increase, the resonant frequency of koch island patch is lower. therefore koch island patch antenna can reduce patch size compared with square patch antenna. and The fabricated patch antenna is matched by using quarter wave length impedance transformer and return loss and radiation patterns are measured. The measurement result shows that the copolarization pattern of koch patch is similar to that of square patch. The cross polarization power level is -15∼-20dB.
홍경한,전상신,이승재,박찬수,권일욱,김재열,김병철,하옥남 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.4
Fin-tube type(Fin-type) heat exchanger has been tested in order to replace the heat exchanger of parallel flow type(P.F-type) which is now widly used in automobile air conditioning system. The following conclusions are drawn by the comparison of the characteristics of the heat exchangers. Evaporator and condenser capacities and COP(Coefficience of performance) were varied as with the compressor speed, outdoor air temperature and air flow rate changed, which much influenced on the characteristics of the air conditioning system. Evaporator and condenser capacities were increased with increasing compressor speed and outdoor air temperature. Evaporator and condenser pressures of Fin- type were decreased by 7% and 5% respectively compared with those of P.F-type. The COP of Fin-type was decreased with increasing outdoor air temperature and compressor speed. The COP of P.F-type was decreased by 14% compared with that of Fin-type.