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일부 산업장 근로자들의 직업성 피부질환 및 천식의 유병조사
윤지석,이영수,조영채,이동배 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2
For the analysis of prevalence of occupational skin diseases and asthma in industrial workers, we studied the 1,274 workers who were engaged in manufacturing workers(direct exposured group to harzardous materials) and clerical workers (indirect exposured group to harzardous materials). The results were as follows: 1. The prevalence rate of occupational skin diseases and asthma in manufacturing workers(36.4%) was significantly higher than that in clerical workers(25.2%) (p<0.005). 2. The prevalence rates of skin diseases(p<0.005) and asthma(p<0.05) in male manufacturing workers were significantly higher than those in clerical workers, and the prevalence rate of asthma(p<0.005) in female manufacturing workers was significantly higher than that in clerical workers. 3. Of asthma in twenties(p<0.005), of skin diseases(p<0.005) and asthma(p<0.05) in thirties, the prevalance rate of manufaturing workers were higher than thoses of clerical workers, however no diffrence was in forties. 4. Of skin diseases(p<0.005) and asthma(p<0.05) in metal plating, of asthma(p<0.005) in cotton spinning, the prevalence rate of manufacturing workers were significantly higher than those of clerical workers. 5. The prevalence rate of skin diseases and asthma in dustness part were significantly higher than those of non-dustness part and poor ventilation part also were significantly higher than good ventilation part (p<0.005). 6. Frequency of involved skin sites, in descending order, were hand(32.1%), leg(24.3%), trunk(20.4%), face(12.1%) and arm(11.1%).
윤지석(Ji Seog Yoon),김영호(Yeong Ho Kim),서기범(Ki Beom Suhr),이증훈(Jeung Hoon Lee),박장규(Jang Kyu Park) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.4
Infantile digital fibromatoais is a rare benign tumor on fingers and toes of infants and childhood characterized by fibroblaatic proliferation. A 6 months old male infant had a bean sized, flesh nodule on th left 3rd finger. The lesion was noted at 3 days after birth and surgically removed at 7 months old, However, a new lesion developed at the margin of the ald lesion 2 months later. The second patient was a 21 months old female who had two bean sized, flesh nodules on the right 4th snd 5th fingers. The lesion was first noted at 12 months and regressed spontaneously at 30 months without specific interventiona. Histopathological examination of the two cases showed eosinophiric ntracytoplasmic inclusion bodies, charateristic for infantile digital fibromatosis. (Kor J Dermatol 1994; 32(4): 682-686)
석지윤(Seog, Ji-Yoon) 동아대학교 법학연구소 2019 東亞法學 Vol.- No.82
지체상금은 채무자에 대한 심리강제를 통하여 채무의 이행을 확보하고, 도급인의 손해액에 대한 입증 곤란을 덜고, 다툼을 사전에 예방하여 손해배상에 관한 법률관계를 간명하게 처리할 목적에서 체결된다. 수급인의 채무의 이행을 확보하고, 입증의 곤란을 피하는 것이 지체상금제도의 취지인 점, 우리 민법 제398조 제4항이 위약금의 약정을 손해배상액의 예정으로 추정하고 있고, 이를 위약벌로 볼 경우 수급인에게 지나치게 가혹하다는 점에 비추어 해석에 의해 지체상금을 손해배상액의 예정인지 아니면 위약벌인지 확정할 수 없는 경우에는 손해배상액의 예정으로 추정함이 타당하다. 지체상금률은 연 이자율로 환산할 때 18%이상으로 대가 지급 지연에 따른 이자율이 연 3.5%인 점에 비추어 매우 높다. 양 당사자가 상호 만족할 수 있도록 지체상금률의 경우 공사의 규모나 종류를 감안하여 공사계약금액에 따라 차등적으로 적용하는 것이 적절하다고 생각된다. 또한 지체상금의 상한을 두어 그 한도를 계약 보증금 상당액으로 제한하는 것이 바람직하다. 지체상금과 관련한 분쟁은 법리적인 다툼보다는 면책사유의 존부, 지체상금의 산정기간, 감액의 인정여부 등 사실관계의 확정에 있다고 볼 수 있다. 그러므로 지체상금과 관련된 분쟁을 최소화하기 위해 실제 거래상 자주 사용하는 『공사계약일반조건』,『민간건설공사 표준도급계약 일반조건』등을 개정하여 지체상금의 상한액에 대한 제한을 두고, 지체상금률을 차등적용하고, 계약기간의 연장 사유를 유연하게 할 필요가 있다. Liquidated damages for delay are concluded for the purpose of ensuring the fulfillment of obligations through the psychological enforcement of the debtor, avoiding difficulties in proving the damages of the contractor, preventing the strife in advance and simplifying the legal relationship concerning damages. In order to secure the fulfillment of the obligations of the provider and to avoid the difficulties of verification, it is the purpose of the delayed pension system, Article 398 (4) of the Civil Code assumes that the contract of the penalty is the planned amount of damages, In the light of the fact that it is too harsh for the supplier, it is reasonable to assume that the compensation prize is the planned amount of compensation for damages or the compensation for damages if it can not be confirmed. The Rate of liquidated damages for delay rate is 18% or more when converted to annual interest rate, which is very high in view of the 3.5% annual interest rate. In order to ensure mutual satisfaction between the two parties, it is desirable to apply the differentiated payment rate according to the amount of the contract in consideration of the size and kind of the corporation. It is also desirable to limit the upper limit of the money to the contract deposit. The dispute related to the liquidated damages for delay can be regarded as the confirmation of facts such as the existence of the cause of exemption, the calculation period of the liquidated damages for delay, and the recognition of the reduction rather than the legal dispute. Therefore, in order to minimize the disputes related to the liquidated damages for delay, it is necessary to revise the general conditions of construction contracts and the general conditions of contracts of private construction contracts, which are frequently used in actual transactions, so as to limit the upper limit of rate of liquidated damages for delay, And it is necessary to flexibly extend the contract period.
윤지석(Ji Seog Yoon),김영호(Yeong Ho Kim),이증훈(Jeung Hoon Lee),송계용(Kye Yong Song),박장규(Jang Kyu Park) 대한피부과학회 1993 대한피부과학회지 Vol.31 No.5
We report a case of xanthoma disseminatum in a 24 year old male paitient. Multiple yellow-brown papules developed on the flexor aurfaces, such as the neck, axillae, antecubital fossae, groin, and perianal regions. Some papules were detected arouns the eyes and uvulai. biopsy specimen revealed a dense infiltrate of histiocytes, foam cells, Touton giant cells, and other inflammatory cells. No Langerhans granules were seen in the electron microscopic analysis. (Kor J Dermatol 1993;31(5):812-816)
Yoon, Dae Hwa,Lee, Sang Sook,Park, Hyun Ji,Lyu, Jae Il,Chong, Won Seog,Liu, Jang Ryol,Kim, Beom-Gi,Ahn, Jun Cheul,Cho, Hye Sun Oxford University Press 2016 Journal of experimental botany Vol.67 No.1
<P>AtCYP19-4 (also known as CYP5) was previously identified as interacting <I>in vitro</I> with GNOM, a member of a large family of ARF guanine nucleotide exchange factors that is required for proper polar localization of the auxin efflux carrier PIN1. The present study demonstrated that <I>OsCYP19-4,</I> a gene encoding a putative homologue of AtCYP19-4, was up-regulated by several stresses and showed over 10-fold up-regulation in response to cold. The study further demonstrated that the promoter of <I>OsCYP19-4</I> was activated in response to cold stress. An OsCYP19-4-GFP fusion protein was targeted to the outside of the plasma membrane via the endoplasmic reticulum as determined using brefeldin A, a vesicle trafficking inhibitor. An <I>in vitro</I> assay with a synthetic substrate oligomer confirmed that OsCYP19-4 had peptidyl-prolyl <I>cis-trans</I> isomerase activity, as was previously reported for AtCYP19-4. Rice plants overexpressing <I>OsCYP19-4</I> showed cold-resistance phenotypes with significantly increased tiller and spike numbers, and consequently enhanced grain weight, compared with wild-type plants. Based on these results, the authors suggest that OsCYP19-4 is required for developmental acclimation to environmental stresses, especially cold. Furthermore, the results point to the potential of manipulating <I>OsCYP19-4</I> expression to enhance cold tolerance or to increase biomass.</P>