베타-아밀로이드 펩타이드로 유발된 신경세포사와 tau 인산화와의 연관성

김지형,홍혜남,이종환,황승준,박형섭,이흥식,김동호 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.4

5인 미만 사업장의 산업안전 규제 순응 실태

이관형,이경용,손두익,서남규,서광국,오지영 한국안전학회 2003 한국안전학회지 Vol.18 No.4

This study is planned to investigate the compliance of small sized enterprises of under 5 employees directed by Industrial Safety and Health Act. Occupational safety regulation can be required for employer and employee to comply because that all members of workplace should be involved to protect worker's health. When all members of workplace comply with safety regulation, effectiveness of regulation will be realized as expectation. The study subject is composed of three groups as 501 employers, 501 employees of small sized enterprises of under 5 employees and 107 safety inspectors sampled by stratified random sampling for comparison. Data for analysis is collected from each sample using interview with structured questionnaires. Compliance is measured by 5 point scale composed by 8 sub items such as general perception, understanding, clearness, necessity, relevancy, implementation, penalty, and general compliance of the regulation. Among sub items of employer's compliance, the level of perception of regulation, necessity of regulation, relevancy of penalty are differentiated among three groups. The level of all 8 items of employee's compliance also differentiated among three groups. These results show that strategies for ensuring the same level of compliance among three groups will be needed through education, training and evaluation of regulation and feedback.

떫은감 탄닌성분이 초산발효에 미치는 영향

서지형,김영지,김주남 영남이공대학 산업기술연구소 2002 産業技術硏究 Vol.14 No.-

To improve the quality of persimmon vinegars, this study was investigated effects of persimmon tannin on acetic acid fermentation. During fermentation sugar contents didn't changed in all groups. Total acidity of 0.15 % tannin group was very low, only 2.5 %. Browning reaction during acetic acid fermentation increased continuously. Especially the color values and turbidity of 0.15 % tannin group were different from other groups. The contents of total phenolic materials and tannin decreased during acetic acid fermentation.

혈우병 환자의 임상 양상에 관한 단일기관 연구

허지혜,김형욱,김영대,이영호,김남수,설인준,김상우 인제대학교 2006 仁濟醫學 Vol.27 No.-

Objective : We analyzed and investigated clinical manifestations, laboratory tests, and inhibitor development of hemophilia that had not been thoroughly studied. Methods : We retrospectively reviewed 96 patients with hemophilia who were registered in the Hanyang University hospital from Jan, 1984 to Dec, 2003, Results : The total patients, whose median age at onset was 46.0 months, in clude 84 cases of type A (87.5%) and 12 cases of type B (12.5%). The most common chief complaint was a traumatic hemorrhage. The family histories of hemophilia were revealed in 41 cases (42.7%). The median activated partial thromboplastin time (aPTT) was 66.7 seconds. The number of severe cases was 39 (40.6%). Inhibitors were present in 13 cases (13.5%) and seven cases (53.8%) were high responders. aPTT and factor levels showed reverse correlation (r=-0.467). aPTT is more prolonged in group without family history than the group with family history (P=0.037). Conclusion : In this study, the diagnosis of hemophilia are made at the lower age and the serological positivity of the HCV is decreased. Activated partial thromboplastin time and factor levels shows reverse correlation. Activated partial thromboplastin time is more prolonged in group without family history compared with group with family history. The frequencies of family history are lower than those of other developed countries, because of concealing the family history of hemophilia. The prevalence of the development of inhibitors increased compared with those of previous studies in Korea, but was lower than those of other countries. Further studies would be necessary to decrease the inhibitor development.

인도네시아 지진해일에 대한 의료지원보고

조수형,김선표,최웅지,김성중,조남수,이준영,문성표 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

An unprecedented magnitude of disaster, Tsunami, washed away Southeast Asia, on December 26, 2004. and more than 200,000 peoples were killed by the disaster. Staffs of our hospital visited Indonesia for voluntary medical supports from January 12, to January 21, 2005. We summarize here our 10 days' experiences in Indonesia.

모기업 협력업체 산업안전보건관리에 대한 인식

이경용,이관형,오지영,서남규,손두익,갈원모,신문진 한국안전학회 2003 한국안전학회지 Vol.18 No.4

This study is planned to investigate the attitude toward the safety and health management of contractor comparry. Under the contract based production system, all of activities including safety and health management in the contractor company are depended upon the contract. How to make contract influence the worker's health of contractor company. Work's health of contractor company can be protected by efforts of company of contract-out and contractor company, especially their safety managers. The modelling of the effective safety and health management system for contractor company should consider the need of safety manager of each company and employer of contractor company. Data is collected from safety managers of 3 contract out companies as electronic and electrical manufacturing industry and 55 safety managers, 57 employers of their contractor companies using self administered survey with structured questionnaire. The most of all respondents want to support from the contract out companies. The most important items supported from contract out company is the information based on the safety information network between each company. Safety manager and employer of contactor company also itemized safety education and training in the supporting system from contract out company. These results can be generalized to survey on the other industries.

누두흉 환자에서 Nuss 금속막대 제거 전 · 후 폐 역학 변화

강규식,백남순,김천숙,안기량,권진형,김지은,유시현 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Nuss operation is one of the surgical procedure for pectus excavatum and it's method is the insertion of convex steel bar under the sternum through small bilateral thoracic incision. As the patients is growing, the thorax can be compressed gradually by steel bar. So Nuss bar needs to be removed two years after Nuss operation. This study was undertaken to assess the effect on the repiratory mechanics before and after the removal of the Nuss bar. Twenty patients with previous Nuss operation were allocated for the removal of Nuss bar. Lung mechanics (dynamic lung compliance, static lung compliance, and airway resistance), hemodynamic change (heart rate, systolic pressure, and diastolic pressure), and pulmonary gas exchange (arterial oxygen tension, arterial carbon dioxide tension, pulse oximeter saturation, and end tidal carbon dioxide tension) were measured before and after removal of Nuss bar. Respiratory mechanics (dynamic and static lung compliance, inspiratory airway resistance), pulmonary gas exchange and hemodynamic parameter were unchanged before and after the removal of Nuss bar. We concluded that lung mechanics were not changed before and after the removal of Nuss bar in the patients with pectus excavatum and the 95% patients were satisfied with operation.

관절가동범위 제한과 통증을 호소하는 Whiplash Injury 환자에 대한 봉독약침요법과 MET 및 평형침법 복합치료 치험 1례

김정록(Jeong Rock Kim),박소현(So Hyun Park),김성아(Sung A Kim),이운형(Un Hyung Lee),이윤지(Yoon Ji Lee),이승훈(Jae Dong Lee),이재동(Seung Hoon Lee),남동우(Dong Woo Nam) 대한스포츠한의학회 2022 대한스포츠한의학회지 Vol.22 No.1

Objectives The aim of this case report is to suggest the effects of Bee-venom pharmacopuncture, acupoint of Pyung-Hyung acupuncture and MET treatment on improving the cervical pain and ROM restriction, Satisfaction of treatment in a 60-year-old male patient after whiplash injury. Methods Patient was treated with Complex Traditional Korean Medical Care of bee venom pharmacopuncture, Kyung-Tong(頸痛) acupoint of Pyung-Hyung Acupuncture(平衡鍼法) and MET treatment. Parmacopuncture was performed on pain site. MET treatment was performed on upper trapezius muscle, levator scapulae and sternocleidomastoid muscle. Patient’s symptom was evaluated by Range of motion(ROM), NRS(Numeric Rating Scale), Neck Disability Index(NDI) to check improvement in cervicalgia. Patient’s satisfaction was measured by five-point Likert scale. The treatment was executed once per everyday between March 7-13, 2022. Results After seven session of bee-venom pharmacopuncture, Pyung-Hyung acupuncture and MET method, patient’s ROM, NRS , NDI were improved. Conclusions The results show that Integrative Korean Medicine of pharmacopuncture, Pyung-Hyung Acupuncture and MET treatment can be an effective way to relieve cervicalgia with whiplash injury,

Propofol Alone versus Propofol in Combination with Midazolam for Sedative Endoscopy in Patients with Paradoxical Reactions to Midazolam

Ji Hyung Nam,Dong Kee Jang,Jun Kyu Lee,Hyoun Woo Kang,Byung-Wook Kim,Byung Ik Jang 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.2

Background/Aims: The efficacy of propofol in gastrointestinal endoscopy for patients with midazolam-induced paradoxicalreactions remains unclarified. This study aimed to compare the efficacy and safety of propofol-based sedation in patients whopreviously experienced paradoxical reactions. Methods: This was a prospective, single-blinded, randomized controlled pilot study. Participants with a history of paradoxical reactions tomidazolam during a previous esophagogastroduodenoscopy were recruited and randomly assigned to group I (propofol monosedation)or group II (combination of propofol and midazolam). The primary endpoint was the occurrence of a paradoxical reaction. Results: A total of 30 participants (mean age, 54.7±12.6 years; male, 19/30) were randomly assigned to group I (n=16) or group II(n=14). There were no paradoxical reactions in group I, but there were two in group II, without a significant difference (p=0.209). The mean dose of propofol was higher in group I than in group II (p=0.002). Meanwhile, the procedure and recovery times did notdiffer between groups. Conclusions: Propofol-based sedation was safe and effective for patients who experienced paradoxical reactions to midazolam. However, caution is needed because few cases of paradoxical reaction again can happen in group II in which midazolam wasreadministered.

Comparison of Oral Sulfate Solution and Polyethylene Glycol Plus Ascorbic Acid on the Efficacy of Bowel Preparation

Ji Hyung Nam,홍석보,임윤정,이성주,Hyoun Woo Kang,Jae Hak Kim,Jin Ho Lee 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.5

Background/Aims: The quality of bowel preparation is one of the quality indicators for colonoscopy. The aim of this study was tocompare the efficacy of oral sulfate solution (OSS) and polyethylene glycol plus ascorbic acid (PEG-AA) for bowel preparation. Methods: The study involved 167 patients who underwent diagnostic colonoscopies. Inadequate bowel preparation was definedas any score of ≤1 in each colon section based on the Boston Bowel Preparation Scale. Multivariate logistic regression was used tocompare the efficacy of OSS and PEG-AA. Subgroup analyses were performed based on patient characteristics. Results: Overall, 106 (63.5%) patients received OSS, and 61 (36.5%) patients received PEG-AA. The rate of inadequate bowel preparation was 12.3% in patients receiving OSS and 32.8% in patients receiving PEG-AA (p=0.001). OSS (odds ratio [OR] = 0.26; p=0.003) and morning examination (OR=0.11; p=0.038) were significantly associated with efficient bowel preparation. The efficacyof OSS compared with PEG-AA was only significant in patients ≥50 years of age vs. <50 years of age (OR=0.13; p=0.001 vs. OR=0.96; p=0.959) and female vs. male patients (OR=0.06; p=0.002 vs. OR=0.58; p=0.339). Conclusions: OSS was significantly more efficient for bowel preparation than PEG-AA, especially in patients ≥50 years of age and female patients. Morning examination led to a good quality of bowel preparation, irrespective of the preparation regimen.