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정창진 ( Chang Jin Jung ),이유정 ( Yu Jung Lee ),김재욱 ( Jaeuk U. Kim ),김근호 ( Keun Ho Kim ) 대한한의진단학회 2013 大韓韓醫診斷學會誌 Vol.17 No.2
Objectives Tongue diagnosis is an important diagnostic method in traditional Eastern medicine, and it has a high potential to be used in the future healthcare because of easy, quick, and non-contact measuring features. Recently, research and development efforts on computerized tongue diagnosis systems (CTDS) have been active that led to the technical advancements in the field of photographing techniques, image extraction and classification algorithms. In this study, we analyzed the trends in the CTDS patents. Using the WIPS search engine (www.wipsglobal.com), quantitative and qualitative patent analyses were performed through Korea, China, Japan, U.S.A and Europe. Methods For a systematic search and data analysis, we defined patent categories based on the application area and technical details. By applying thus-obtained categorical key words, we obtained 360 relevant patents on photographing techniques, image extraction and classification algorithms for the purpose of diagnosis or security. Results As a result, companies related to image acquisition, medical imaging and mobile devices and research groups of universities in East Asia were major patent applicants. In all the five countries, the number of patents have been increasing since 1980. In particular, technology related to color correction and image segmentation were most actively patented categories, and expected to continue a high application rate.
Kim, Jaeuk U.,Ku, Boncho,Kim, Young-Min,Do, Jun-Hyeong,Jang, Jun-Su,Jang, Eunsu,Jeon, Young Ju,Kim, Keun Ho,Kim, Jong Yeol Hindawi Publishing Corporation 2013 Evidence-based Complementary and Alternative Medic Vol.2013 No.-
<P>Sasang constitutional medicine (SCM) shares its philosophy with that of personalized medicine: it provides constitution-specific treatment and healthcare individualized for each patient. In this work, we propose the concept of the Sasang Health Index (SHI) as an attempt to assess the individualized health status in the framework of SCM. From the target population of females in their fifties and older, we recruited 298 subjects and collected their physiological data, including complexion, radial pulse, and voice, and their questionnaire responses. The health status of each subject was evaluated by two Korean medical doctors independently, and the SHI model was obtained by combining all the integrative features of the phenotype data using a regression technique. As a result, most subjects belonged to either the healthy, subhealthy, or slightly diseased group, and the intraclass correlation coefficient between the two doctors' health scoring reached 0.95. We obtained an SHI model for each constitution type with adjusted <I>R</I>-squares of 0.50, 0.56, and 0.30, for the TE, SE, and SY constitution types, respectively. In the proposed SHI model, the significant characteristics used in the health assessment consisted of constitution-specific features in accordance with the classic literature and features common to all the constitution types.</P>
Kim, Jaeuk U.,Lee, Yu Jung,Lee, Jeon,Kim, Jong Yeol Hindawi Publishing Corporation 2015 Evidence-based Complementary and Alternative Medic Vol.2015 No.-
<P><I>Aim of the Study</I>. The three conventional pulse-diagnostic palpation locations (PLs) on both wrists are <I>Cun</I>, <I>Guan</I>, and <I>Chi</I>, and each location reveals different clinical information. To identify anatomical or hemodynamic specificity, we used ultrasonographic imaging to determine the arterial diameter, radial artery depth, and arterial blood flow velocity at the three PLs and at nearby non-PL segments. <I>Methods</I>. We applied an ultrasound scanner to 44 subjects and studied the changes in the arterial diameter and depth as well as in the average/maximum blood flow velocities along the radial artery at three PLs and three non-PLs located more proximally than <I>Chi</I>. <I>Results</I>. All of the measurements at all of the PLs were significantly different (<I>P</I> < 0.01). Artery depth was significantly different among the non-PLs; however, this difference became insignificant after normalization to the arm circumference. <I>Conclusions</I>. Substantial changes in the hemodynamic and anatomical properties of the radial artery around the three PLs were insignificant at the nearby non-PLs segments. This finding may provide a partial explanation for the diagnostic use of “<I>Cun</I>, <I>Guan</I>, and <I>Chi.</I>”</P>
Change in radial artery pulse wave in stroke hemiplegic patients
Kim, Jaeuk U.,Kim, Jae Kyoun,Shin, Jae-Young,Ku, Boncho,Bae, Jang-Han,Yeom, Seungryong,Lee, Sangkwan Williams & Wilkins Co 2018 Medicine Vol.97 No.13
<P><B>Abstract</B></P><P><B>Introduction:</B></P><P>About 55% to 75% of stroke survivors have motor disorders and problems that affect their quality of life. The prevention of secondary neurological damages through relapse prevention and the rehabilitation of stroke patients suffering from morbidities are crucial to improve the prognosis of patients with stroke. Pulse examinations can be used to determine the stroke progression. This study will investigate the differences and changes in radial artery pressure-pulse waves during the treatment of hemiplegia caused by stroke.</P><P><B>Methods/design:</B></P><P>This study protocol is for a prospective matched case-control study. A total of 84 participants will be recruited, 56 patients with hemiplia caused by stroke, and 28 control patients matched by age, gender, and body mass index. The primary outcome of this study will be the differences and changes in the radial augmentation index.</P><P><B>Discussion:</B></P><P>The results of the study will help to determine the differences and changes in radial artery pressure-pulse waves during the treatment of hemiplegia caused by stroke. The findings will provide information about the physiological and hemodynamic mechanisms.</P><P><B>Conclusion:</B></P><P>This will be the first study to analyze the pulse wave of the radial artery (PWRA) on the affected side and on the normal side in stroke patients with hemiplegia. This study will clarify whether the radial artery pressure pulse wave can be used to evaluate the result of stroke treatment objectively. The results of the study will be available in February 2019. The version of the protocol is v1.6 written in March 7, 2016.</P><P><B>Ethics and dissemination:</B></P><P>Written informed consent will be obtained from all participants. This study has been approved by the Institutional Review Board (IRB) of Wonkwang University Gwangju Hospital, Gwangju, Republic of Korea (WKIRB-2016/8). The study findings will be published in peer-reviewed journals and presented at national and international conferences.</P><P><B>Trial registration number:</B></P><P>This trial was registered with the Clinical Research Information Service (CRIS) of the Korea National Institute of Health (NIH), Republic of Korea (KCT0002147).</P>
김재욱(Jaeuk U. Kim),김성훈(Sung Hun Kim),이유정(Yu Jung Lee),전영주(Young Ju Jeon),강재환(Jaehwan Kang),김종열(Jong Yeol Kim) 대한전기학회 2009 정보 및 제어 심포지엄 논문집 Vol.2009 No.10
Pulse diagnosis is one of the most important diagnosis method in Oriental medicine. To make the pulse diagnosis more objective and standardize, it is essential to reinterpret the pulse images in the literature in terms of the physical quantities such as the strength, width, length, and depth of the pulse waveform, as well as to develop a high fidelity pulse measuring instrument. As a way towards such quantification, in this work, we introduce an effective method of extracting the characteristic features of the measured pulse wave. As an application of so-obtained features of the pulse wave, we outline the procedure of calculating the coefficient of the floating/sinking pulse, which is effective in quantifying the floating pulse and sinking pulse in a unified scale. In addition, we apply the algorithm of calculating the floating/sinking pulse to the database of pulse waves at Chon, Gwan, and Cheok in the left wrist, which were collected from 213 healthy male subjects in their 20s. As a result, we found that statistically the pulse image at Gwan tends to be relatively floating and the pulse image at Cheok tends to be relatively sinking.
김기원(Keewon Kim),김재욱(Jaeuk U. Kim),백현만(Hyun Man Beak),김성균(Sung Kyun Kim) 대한기계학회 2016 大韓機械學會論文集B Vol.40 No.4
하지혈관에 비해 상지혈관질환은 드물기 때문에 상지혈관계에 대한 실험적, 수치해석적 연구는 매우 드물다. 본 논문에서는 최초로 MRA 영상데이터로부터 한국 성인 왼팔의 혈관계, 상완동맥에서 1 ㎜ 이상의 손가락동맥들에 이르는, 3차원 컴퓨터 모델을 제작하였다. 이 모델에 대해 수치해석을 수행하여 정상, 주기유동에 대한 속도장, 압력장을 계산하였고 주요 분지관에서의 유량분배와 벽전단응력분포에 대해 분석하였다. Since arterial disease in the upper extremity is less common than that in the lower extremity, experimental and numerical investigations related to upper extremity have been rarely performed. We created a three-dimensional model of the arteries, larger than approximately 1 mm, in a Korean adult"s left hand (from brachial to digital arteries), from 3T magnetic resonance imaging (MRI) data. For the first time, a three-dimensional computational fluid dynamic method was employed to investigate blood flow velocity, blood pressure variation, and wall shear stress (WSS) on this complicated artery system. Investigations were done on physiological blood flows near the branches of radial and deep palmar arch arteries, and ulnar and superficial palmar arch arteries. The flow is assumed to be laminar and the fluid is assumed to be Newtonian, with density and viscosity properties of plasma.