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소아의 천공형 충수염에서 복강경 충수절제술 및 개복 충수절제술의 비교
박재영(Jae-Young Park),최윤미(Yun-Mee Choe),윤민영(Min-Young Yun),최선근(Sun Keun Choi),허윤석(Yoon-Seok Hur),이건영(Keon-Young Lee),김세중(Sei-Joong Kim),조영업(Young Up Cho),안승익(Seung-Ik Ahn),홍기천(Kee-Chun Hong),신석환(Seok-Hw 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.75 No.2
Purpose: Appendectomy is the most common emergent surgical operation in children. Laparoscopic appendectomy is currently a popular procedure in children, but pediatric laparoscopic appendectomy is controversial for its efficacy and safety, especially for perforated appendicitis. We compared the efficacy and safety between laparoscopic appendectomy (LA) and open appendectomy (OA) for treating perforated appendicitis of children. Methods: This study involved a total of 69 patients who underwent appendectomy for perforated appendicitis at our institution between March 2005 and September 2007, and these patients were less than 15 years old. There were 41 patients in the LA group and 28 patients in the OA group. The demographic data, operative time, length of the hospital stay, bowel movement, pain control and complications were assessed. Results: There was no significant difference between the LA and OA groups with respect to gender, age, the operation time, the length of the hospital stay, bowel movement and pain control. There was one complication (2.4%) in the LA group and four complications (16.6%) in the OA group, but there was no significant difference (P=0.062). There was no wound infection. Conclusion: Laparoscopic appendectomy for the children with perforated appendicitis is a safe procedure. Yet we need further high quality randomized trials to compare the 2 techniques.
김준석 ( Joon Seok Kim ),김용래 ( Yong Rea Kim ),심민섭 ( Min Seob Sim ),조범석 ( Beom Suk Jo ),전찬호 ( Chan Ho Jeon ),안국진 ( Gook Jin An ),이재권 ( Jae Kwon Lee ),안소영 ( Young So An ),강인정 ( In Jung Kang ),남정환 ( Jung Hw 충북대학교 과학교육연구소 2017 과학교육연구논총 Vol.33 No.1
The soybean contain several kinds of triterpenoid saponin with high preventive medicine values. This study investigates the impacts of sulfur processing soybean cultivated with sulfur processing were examined for it configurational property, and then compared with soybean without sulfur processing as a control. A significant decrease in crude saponin content of observed with sulfur processing. Contents of crude saponin decreased about 53% more than non-treated soybean. These results suggest that sulfur processing could be used in the production of teriterpene saponins.
( Jin Won Chang ),( Jae Seung Lee ),( Hye Won Lee ),( Beom Kyung Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Yeon Seok Seo ),( Han Ah Lee ),( Mi Na Kim ),( Yu Rim Lee ),( Seong Gyu Hw 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Several prediction scores are available for the early detection of hepatocellular carcinoma (HCC). We validated the predictive accuracy of the AASL, RESCUE-B, PAGE-B, and modified PAGE-B (mPAGE-B) scores in patients with chronic hepatitis B (CHB) treated with entecavir (ETV) or tenofovir disoproxil fumarate (TDF). Methods: Between 2007 and 2014, 3,171 patients were recruited (1,645 with ETV and 1,517 with TDF). The predictive accuracy of each prediction score was assessed. Results: The mean age of the study population (1,977 men and 1,194 women) was 48.8 years. Liver cirrhosis was noted in 1,040 (32.8%) patients. During follow-up (median, 58.2 months), 280 (8.8%) patients developed HCC and were significantly older; were more likely to be male; had significantly higher proportions of liver cirrhosis, hypertension, and diabetes; and had significantly higher values of the four risk scores than those who did not develop HCC (all P<0.05). Older age (hazard ratio [HR]=1.048), male sex (HR=2.142), liver cirrhosis (HR=3.144), and prolonged prothrombin time (HR=2.589) were independently associated with an increased risk of HCC development (all P<0.05), whereas a higher platelet count (HR=0.996) was independently associated with a decreased risk (P<0.05). The predictive accuracy of the AASL score was highest at 3 and 5 years HCC prediction (area under the curve [AUC]=0.818 and 0.816, respectively), followed by RESCUE-B, PAGE-B, and mPAGE-B scores (AUC=0.780-0.815 and 0.769-0.814, respectively). Conclusions: Four HCC prediction scores performed acceptably in Korean patients with CHB treated with ETV or TDF. Of these, the AASL score showed the highest predictive accuracy.
Yoon soo Park,Hyun Jin Tae,Jeong Hwi Cho,In Shik Kim,Taek Geun Ohk,Chan Woo Park,Joong Bum Moon,Myoung Cheol Shin,Tae Kyeong Lee,Jae Chul Lee,Joon Ha Park,Ji Hyeon Ahn,Seok Hoon Kang,Moo Ho Won,Jun Hw 대한해부학회 2018 Anatomy & Cell Biology Vol.51 No.2
Cardiac arrest (CA) is sudden loss of heart function and abrupt stop in effective blood flow to the body. The patients who initially achieve return of spontaneous circulation (RoSC) after CA have low survival rate. It has been known that multiorgan dysfunctions after RoSC are associated with high morbidity and mortality. Most previous studies have focused on the heart and brain in RoSC after CA. Therefore, the aim of this research was to perform serological, physiological, and histopathology study in the lung and to determine whether or how pulmonary dysfunction is associated with low survival rate after CA. Experimental animals were divided into sham-operated group (n=14 at each point in time), which was not subjected to CA operation, and CA-operated group (n=14 at each point in time), which was subjected to CA. The rats in each group were sacrificed at 6 hours, 12 hours, 24 hours, and 2 days, respectively, after RoSC. Then, pathological changes of the lungs were analyzed by hematoxylin and eosin staining, Western blot and immunohistochemistry for tumor necrosis factor (TNF-). The survival rate after CA was decreased with time past. We found that histopathological score and TNF- immunoreactivity were significantly increased in the lung after CA. These results indicate that inflammation triggered by ischemia-reperfusion damage after CA leads to pulmonary injury/dysfunctions and contributes to low survival rate. In addition, the finding of increase in TNF- via inflammation in the lung after CA would be able to utilize therapeutic or diagnostic measures in the future.