골격성 제3급 부정교합환자의 하악지 시상분할 골절단술후 하안면 폭경 및 고경의 변화에 대한 두부계측 방사선학적 연구

장현석,임재석,권종진,이부규,손형민 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.3

Purpose : The purpose of this study was to analyze the lower third facial changes in frontal view after mandibular setback surgery. Materials and Methods : In this study, fifteen subjects(6 males and 9 females) with class III dental and skeletal malocclusions who were treated with BSSRO(Bilateral Sagittal Split Ramus Ostetomy) were used. Frontal cephalometric radiographs were taken preoperatively and more than 6 months postoperatively, and hard tissue(H2-Hl) and soft tissue changes (S2-S1) were measured on vertical and horizontal reference lines. In 15 cases, changes which developed more than 6 months after surgery were studied. Results : The results were as follows. 1.In the facial height, hard tissue decreased(2.46±2.76mm) with statistical significance(P<0.01), and soft tissue also decreased(1.64±3.66mm). As a result, the facial height generally becomes shorter after sagittal split ramus osteotomy. 2.In the mandibular width, hard tissue decreased(2.08±3.59mm) with statistical sgnificance(P<0.05), but soft tissue increased (2.14±5.73mm) without statistically significant difference (P>0.05) postoperatively. 3.In the facial index, hard tissue decreased(0.23±2.21%), but soft tissue increased(2.41±3.46%) with statistical significance. Conclusion : One of the main purpose of orthognathic surgery is to achieve facial esthetics and harmony. In order to fullfill this purpose, it is important to carry out a precise presurgical treatment planning by estimating the changes of frontal profile after surgery.

스티렌 현탁 중합반응에서 폭주반응 해석

박형일,신석주,이헌창,장서일,김태옥 한국산업안전학회 2002 한국안전학회지 Vol.17 No.3

The runaway reaction was analyzed experimently and theoretically at the batch styrene suspension polymerization process. In the experiments, the reaction temperature with time was measured at various experimental conditions. According to the experimental results, the risk of the runaway reaction was increased with increasing the ratio of the monomer(styrene, M) to the dispersion medium(water, W), the concentration of the initiator(BPO), and the monomer mass, respectively. And simulation results showed that the runaway reaction was significantly affected by the reaction rate constant of the propagation and that the phenomena of the runaway reaction occurred at about 70% conversion. Also, we found that the runaway reaction did not occur under the operation condition of below 0.5 for M/W, approximate 3 wt% BPO, and below 75℃ for the cooling temperature.

Bacillus lentimorbus WJ5의 감마선유도 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자의 microarray 분석

이영근,장화형,장유신,허재호,형석원,정혜영 한국환경생물학회 2004 환경생물 : 환경생물학회지 Vol.22 No.3

본 연구에서는 감마선으로 유도된 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자들의 발현을 연구하기 위하여, B. lentimorbus WJ5의 방사선 유도 돌연변이체에서 발현되는 유전자를 DNA microarray로 동시에 탐색하였다. DNA microarray는 B. lentimorbus WJ5 genome을 무작위로 절단하여 2,000단편으로 구성하였으며, 감마선 (^(60)Co)으로 유도된 7돌연변이체의 발현을 정량적으로 관찰하였다. 클러스터 분석결과 발현된 408 유전자 중 27개가 감마선 유도 돌연변이체 모두에서 유의하게 발현이 증가되었다. 특히, 복구(mutL, mutM)에너지 대사 (acsA, sdhB, p하, yhjB, citB), protease(npr), 산화자극에 대한 환원 (HMM)관련 유전자들이 동시에 증가되었다. 이는 감마선 유도 돌연변이체들에서 자발적인 직/간접 복구 관련 유전자의 발현 증가는 방사선 노출 직후 보이는 stress response와는 다른 현상임을 나타내는 것으로 생각된다. To study the radiation related gene expression in mutants of Bacillus lentimorbus WJ5 induced by gamm radiation, the simultaneous gene expression was analyzed by DNA microarray. We constructed DNA chips including two thousand randomly digested genome spots of B. lentimorbus WJ5 and compared its quantitative aspect with seven mutants induced by gamma radiation (^(60)Co). From the cluster analysis of gene expression pattern, totally 408 genes were expressed and 27 genes were significantly upregulated by the gamma radiation in all mutants. Especially, genes involved in repair (mutL, mutM), energy metabolism (acsA, sdhB, pgk, yhjB, citB), protease (npr), and reduction response to oxidative stress (HMM) were simultaneously upregulated. It seems that the induction of the direct and/or indirect repair related genes in mutants induced by gamma radiation could be remarkably different from the adaptive responses against acute exposure to radiation.

Bacillus sp. MS202에 의한 Dinitroaniline계 제초제인 Pendimethalin의 부분환원

이영근,장화형,장유신,형석원,정혜영 한국환경농학회 2004 한국환경농학회지 Vol.23 No.4

토양과 지하수에서 pendimethalin의 지속성은 환경에 해로운 영향을 미친다. 경남 마산에서 분리한 pendimethalin분해 균주는 API CHB50 kit 시험, FAME 분석, 그리고 165 rDNA 염기서열분석 결과로 Bacillus sp. MS202로 잠정적으로 동정하였다. TLC, GC, 그리고 GC-MS 분석에 의해 Bacillus sp. MS202가 pendimethalin의 -NO₂를 -NH₂로 환원시킨다는 것을 알 수 있었다. 이는 일반적으로 알려진 호기성 미생물에 의한 pendimethalin 분해가 탈알킬화가 우선한다는 보고와 상반되는 새로운 결과이다. The persistence of pendimethalin in soil and ground water has an injurious effect on ecosystem. Pendimethalin-degrading bacterium was isolated from Masan, Gyeongnam province and temporarily identified as Bacillus sp. MS202 by the analysis of API CHB50, kit, FAME, and 16S rDNA sequence. From the analysis of pendimethalin metabolite using TLC, GC, and GC-MS, we found that the degradation of pendimethalin by Bacillus sp. MS202 did not result in the dealkylated form, but the formation of the reduced compound, 6-amino-2-nitro-N(1-ethylpropyl)-3,4-xylidine or 2-amino-6-nitro-N(1-ethylpropyl)-3,4-xylidine.

전치부 개교합을 가진 골격성 제 Ⅲ급 부정교합 환자에 있어서 하악지 시상분할 골절단술후 술후 안정성에 관한 평가

임재석,권종진,장현석,손형민,남영원,최철민 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.6

The purpose of this study is to assess the postoperative stability and the tendency of relapse after both sagittal split ramus osteotomy in skeletal class III with anterior open bite. This retrospective study was based on the examination of 15 patients, 6 males and 9 females, with a mean age 23.1 years. The patients were divided into two groups based on the amount of preoperative overbite(group I:<1mm, group II:≥1mm). Serial lateral cephalometric radiographs were taken within 2 weeks preoperatively, within 1 week postoperatively and at a follow up period that ranged from 7 to 24 months postoperatively. All cephalometric radiographs were traced and digitized using the Quick ceph image Pro for analysis. And then, horizontal and vertical changes of reference points(B point, Pogonion, L1) were assessed by the linear measurements in millimeters on both axes. The results were as follows : 1 Mean horizontal relapses were 0.67±0.93mm (11%) at B point (P<.05) and 0.81±1.01mm (13.2 %) at Pogonion (P<.01). 2, Mean vertical relapses were 0.63±1.62mm (33.3%) at B point and 0.53±1.95mm (31.4%) at Pogonion (P>.05) 3. The mean angular change of occlusal plane to SN was 0.24±1.19 (P>.05) and that of mandibular plane to SN was 1.03±1.85 (P<.05). 4. There was correlation between the extent of preoperative overbite and the postsurgical relapse at B point and Pogonion. 5. There was no correlation between the amount of surgically produced horizontal movement and the postoperative horizontal relapse at B point.

Effects of bee venom on the pro-inflammatory responses in RAW264.7 macrophage cell line

Jang, Hyoung-Seok,Kim, Sun-Kwang,Han, Jae-Bok,Ahn, Hyun-Jong,Bae, Hyun-su,Min, Byung-Il EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The purpose of this study is to elucidate the molecular mechanism of anti-inflammatory effect of bee venom (BV), which has been used for the treatment of various inflammatory diseases in oriental medicine. With this aim, we examined the effects of BV on the nitric oxide (NO) production by lipopolysaccharide (LPS) or sodium nitroprusside in RAW264.7 macrophages. We further investigated the effects of BV on the expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-?B (NF-?B) and mitogen-activated protein kinase (MAPK) with RT-PCR in LPS-stimulated RAW264.7 cells. BV suppressed the NO production and decreased the levels of iNOS, COX-2, NF-?B and MAPK mRNA in a dose-dependent manner. These results suggest that BV has an anti-inflammatory effect by inhibiting iNOS and COX-2 expression, possibly through suppression of NF-?B and MAPK expression.

Influence of calcination and cooling conditions on pozzolanic reactivity of paper mill sludge

Jang, Hong-seok,Lim, Yong-Taek,Kang, Je-Hong,So, Seung-young,So, Hyoung-seok Elsevier 2018 Construction and Building Materials Vol.166 No.-

<P><B>Abstract</B></P> <P>The purpose of this study is to investigate influence of calcination and cooling conditions on pozzolanic reactivity of waste paper sludge. Calcined paper sludge (CPS) is prepared by different temperatures of calcination, duration of calcination and cooling methods. Pozzolanic activity of CPS was investigated by using API (Assessed Pozzolanic Activity Index) and SAI (Strength Activity Index) in accordance with ASTM C618-17 (KS L 5405) and consumption of Ca(OH)<SUB>2</SUB> hydrate in mortars with CPS in detail, and compared to that of commercial fly ash (FA) and blast furnace slag (BFS) used in the concrete industry. Results revealed CPS produced from waste paper sludge had excellent pozzolanic activity compared with commercial pozzolanic admixtures such as FA or BFS. Their pozzolanic activity was most excellent in calcination temperature of 700 °C, calcination duration of 2 h and cooling method of water quenching. SAI (%) of mortar with CPS produced under optimal conditions was 96% at 28 days of age, and satisfied the quality of fly ash (Class F) as specified in ASTM C618-17 (KS L 5405). There was linear relation between API (%) and SAI (%) of mortars with CPS, and the correlation coefficient was relatively good as 0.8 at 28 days of age. The API method is recommended as rapid and appropriate evaluation of the pozzolanic activity of the CPS.</P> <P><B>Highlights</B></P> <P> <UL> <LI> This study focused on investigating the optimum conditions for production of a highly reactive pozzolan by controlled calcination and cooling process of paper sludge. </LI> <LI> Various calcined paper sludge (CPS) were prepared by different calcination and cooling conditions. </LI> <LI> Results revealed CPS produced from waste paper sludge had excellent pozzolanic activity compared with commercial pozzolanic admixtures such as FA or BFS. </LI> <LI> Their pozzolanic activity was most excellent in calcination temperature of 700 °C, calcination duration of 2 hours and cooling method of water quenching. </LI> </UL> </P>

PCB에 인가된 스위칭 잡음이 함체 개구 방사에 미치는 영향

장형석(Hyoung Seok Jang),이숭근(Soong Keun Lee),김은하(Eun Ha Kim),유승렬(Seung Real Ryu),이재현(Jae-Hyun Lee),박동철(Dong Chul Park) 한국전자파학회 2011 한국전자파학회논문지 Vol.22 No.1

본 논문은 능동 소자의 스위칭 잡음이 함체 내부에 위치한 PCB에 인가될 때, 함체의 개구 방사에 미치는 영향을 분석한 연구이다. 이상적인 주기 펄스 입력 신호가 PCB에 인가된 경우의 개구 방사와 스위칭 잡음을 포함한 주기 입력 신호가 인가된 경우의 개구 방사를 비교하였다. DC-DC 컨버터의 등가회로를 이용해 능동소자의 스위칭 잡음을 구현하였으며, 방사 전계 시뮬레이션을 위해 회로 시뮬레이터와 전자기장 시뮬레이터를 연동시켜 해석을 수행하였다. 또한, 측정 결과와 시뮬레이션 결과를 비교하였다. This paper investigates the radiated emission from the enclosure aperture, when the enclosure contains a 4-layer PCB and the PCB is driven by a pulse train additive with the switching noise from an active device. Radiated emission characteristics with and without switch noise cases, respectively, are analyzed by changing the PCB location and the slot direction. The equivalent circuit of a DC-DC converter is used to simulate the switching noise of active device. Also, MWS simulation results are directly connected to the ADS simulator as a 2-port block. The simulated results are compared with the measured ones.

Strength and Microstructure of Reactive Powder Concrete Using Ternary Pozzolanic Materials

So, Hyoung-Seok,Janchivdorj, Khulgadai,Yi, Je-Bang,Jang, Hong-Seok,So, Seung-Young The Korean Institute of Building Construction 2013 한국건축시공학회지 Vol.13 No.1

To consider the practicality and economic feasibility of developing reactive powder concrete (RPC), the strength and microstructure properties of RPC using ternary pozzolanic materials (silica fume, blast furnace slag, fly ash) were investigated in this study. Through the investigation, it was found that the compressive strength of RPC using ternary pozzolanic materials was increased significantly compared to that of the original RPC containing silica fume only. A considerable improvement in the flexural strength of RPC using ternary pozzolanic materials was found, and then the utilization of a structural member subjected to bending was expected. The X-ray diffractometer (XRD) analysis and Scanning Electronic Microscope (SEM) revealed that the microstructure of RPC was denser using the ternary pozzolanic materials than the original RPC.

Mechanical properties and microstructure of reactive powder concrete using ternary pozzolanic materials at elevated temperature

So, Hyoung-seok,Jang, Hong-seok,Khulgadai, Janchivdorj,So, Seung-young Springer-Verlag 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.4