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Kim, Moon Young,Baik, Soon Koo,Yea, Chang Jin,Lee, Il Young,Kim, Hye Jung,Park, Kyong Won,Kim, Hearn Kook,Suk, Ki Tae,Kim, Jae Woo,Kim, Hyun Soo,Kwon, Sang Ok,Cha, Seung Hwan,Kim, Young Ju,Koh, Sang B Lippincott Williams Wilkins, Inc. 2009 European journal of gastroenterology & hepatology Vol.21 No.11
OBJECTIVE: Portal hypertension is closely associated with serious complications of cirrhosis, which contribute to bad prognosis. Hepatocellular carcinoma (HCC) and low serum sodium (SNa) are manifestations of end-stage liver disease and are associated with poor survival in decompensated cirrhosis patients. We aimed to determine the relationship between hepatic venous pressure gradient (HVPG) and the development of HCC or low SNa in decompensated alcoholic cirrhosis patients. METHODS: Child-Pugh scores, Model for End-Stage Liver Disease scores, and HVPG at baseline, and the development of HCC or low SNa (SNa <130 mEq/l) during follow-up were analyzed prospectively in 170 patients with decompensated alcoholic cirrhosis from December 1999 to January 2008 (mean follow-up period of 33.9±27.9 months). The predictive value of different risk factors for the development of HCC and low SNa and survival were investigated. RESULTS: Twenty-four patients developed HCC during the follow-up period. In the multivariate analysis, only baseline HVPG greater than 15 mmHg was an independent predictive factor for the development of HCC (relative risk=1.128, P<0.05) and which showed a significantly shorter time for the development of HCC on the Kaplan–Meier analysis. Twenty patients developed low SNa during follow-up. Initial HVPG was also an independent predictive factor for the new development of low SNa in the multivariate analysis (relative risk=1.169, P<0.05) and which also showed significantly shorter times for the development of low SNa on the Kaplan–Meier analysis. CONCLUSION: In decompensated alcoholic cirrhosis, HVPG may be a useful predictive factor for the development of HCC and low SNa.
Relationship of hepatic venous pressure gradient and prognosis in patients with Liver cirrhosis
Moon Young Kim,Soon Koo Baik,Yoon Ok Jang,Ki Tae Suk,Chang Jin Yea,Il Young Lee,Hye Jung Kim,Hearn Kook Kim,Kyoung Won Park,Jae Woo Kim,Hyun Soo Kim,Sang Ok Kwon,Soon Ho Um,Kwang Hyub Han 대한간학회 2008 Clinical and Molecular Hepatology(대한간학회지) Vol.14 No.3(S)
Cytomegalovirus infection of the gastrointestinal tract: endoscopical aspects (초)
( Kyong Won Park ),( Hye Jeong Kim ),( Hearn Kook Kim ),( Ki Tae Suk ),( Il Young Lee ),( Chang Jin Ye ),( Moon Young Kim ),( Jae Woo Km ),( Hyun Soo Kim ),( Soon Koo Baik ),( Sang Ok Kwon ) 대한내과학회 2008 대한내과학회 추계학술대회 Vol.2008 No.-
Cytomegalovirus infection of the gastrointestinal tract: endoscopical aspects (초)
( Kyong Won Park ),( Hye Jeong Kim ),( Hearn Kook Kim ),( Ki Tae Suk ),( Il Young Lee ),( Chang Jin Ye ),( Moon Young Kim ),( Jae Woo Km ),( Hyun Soo Kim ),( Soon Koo Baik ),( Sang Ok Kwon ) 대한내과학회 2008 대한내과학회지 Vol.75 No.1S
증례 : 소화기 ; 용종 모양을 보인 거대세포바이러스 위장관 감염 1예
박경원 ( Kyong Won Park ),김문영 ( Moon Young Kim ),김혜정 ( Hye Jeong Kim ),김헌국 ( Hearn Kook Kim ),석기태 ( Ki Tae Suk ),정요셉 ( Yo Sep Chong ),조미연 ( Mee Yon Cho ) 대한내과학회 2009 대한내과학회지 Vol.77 No.5S
55세 남자가 수일간의 과량의 음주 후 발생한 상복부 통증으로 본원 응급실 방문하여 시행한 혈액 검사상 알코올성 케톤산증 소견을 보여 입원하여 시행한 위내시경 검사에서 다발성 용종 모양의 병소가 발견되어 조직 검사 시행한 결과 거대세포바이러스 감염으로 확인되었다. 이에 저자들은 내시경 검사에서 용종 모양을 보인 거대세포바이러스 위장 관염을 경험하였기에 보고하는 바이다. A 55-year-old immunocompetent man presented with worsening epigastric pain that developed after he had been drinking alcohol heavily for a few days. He was admitted to our hospital with the diagnosis of alcoholic ketoacidosis based on his laboratory profile. About 34 years earlier, he had undergone a subtotal gastrectomy to treat obstruction of the pyloric channel. Endoscopic examination of the gastrointestinal tract showed yellowish elevated polypoid lesions on the gastric side of the anastomosis site and biopsy specimens revealed cytomegalovirus (CMV) infection with severe chronic inflammation histopathologically. The main reported endoscopic feature of alimentary tract cytomegalovirus disease is ulceration. We report a case of CMV-associated polypoid lesions, which is a rare endoscopic finding, along with a brief review of the literature. (Korean J Med 77:S1115-S1118, 2009)
증례 : 소화기 ; 용종 모양을 보인 거대세포바이러스 위장관 감염 1예
박경원 ( Kyong Won Park ),김문영 ( Moon Young Kim ),김혜정 ( Hye Jeong Kim ),김헌국 ( Hearn Kook Kim ),석기태 ( Ki Tae Suk ),정요셉 ( Yo Sep Chong ),조미연 ( Mee Yon Cho ) 대한내과학회 2009 대한내과학회지 Vol.77 No.7
55세 남자가 수일간의 과량의 음주 후 발생한 상복부 통증으로 본원 응급실 방문하여 시행한 혈액 검사상 알코올성 케톤산증 소견을 보여 입원하여 시행한 위내시경 검사에서 다발성 용종 모양의 병소가 발견되어 조직 검사 시행한 결과 거대세포바이러스 감염으로 확인되었다. 이에 저자들은 내시경 검사에서 용종 모양을 보인 거대세포바이러스 위장 관염을 경험하였기에 보고하는 바이다. A 55-year-old immunocompetent man presented with worsening epigastric pain that developed after he had been drinking alcohol heavily for a few days. He was admitted to our hospital with the diagnosis of alcoholic ketoacidosis based on his laboratory profile. About 34 years earlier, he had undergone a subtotal gastrectomy to treat obstruction of the pyloric channel. Endoscopic examination of the gastrointestinal tract showed yellowish elevated polypoid lesions on the gastric side of the anastomosis site and biopsy specimens revealed cytomegalovirus (CMV) infection with severe chronic inflammation histopathologically. The main reported endoscopic feature of alimentary tract cytomegalovirus disease is ulceration. We report a case of CMV-associated polypoid lesions, which is a rare endoscopic finding, along with a brief review of the literature. (Korean J Med 77:S1115-S1118, 2009)
Ho-Suk Oh,Hyoung-Jung Chung,Hearn-Kook Kim,Jong-Soo Choi 대한암학회 2007 Cancer Research and Treatment Vol.39 No.2
Purpose: The purpose of this study is to determine whether the prognosis can be more precisely gauged by the revised 6th AJCC staging system and if this is suitable for Korean colorectal cancer patients, and especially for those patients in the Youngdong district. Materials and Methods: Between September 1996 and December 2003, 365 patients with histologically confirmed colorectal cancer were analyzed. Kaplan-Meier analyses were used to compare the overall and stage-specific 5-year survival. All the statistical tests were two-sided.Results: The overall 5-year survival for the entire cohort was 62%. According to the stages defined by the AJCC fifth edition system, the 5-year stage-specific survival was 91% for stage I, 82% for stage II, 51% for stage III and 4% for stage IV. According to the stages defined by the AJCC sixth edition system, the 5-year stage-specific survival was 91% for stage I, 81% for stage IIa, 83% for stage IIb, 100% for stage IIIa, 64% for stage IIIb, 37% for stage IIIc and 4% for stage IV. The 5-year survival was significantly better for the patients with stage IIIb (64%) than those patients with stage IIIc (37%) (p〈.001). Conclusion: It is widely known that the AJCC sixth edition system for colorectal cancer stratifies survival more distinctly than does the fifth edition system by providing more substages. Our study showed that stage IIIb disease had better survival than stage IIIc disease, but we couldn't confirm that this new staging system is relevant in our Korean clinical practice due to the small study population. Therefore, further study is required in a larger population. (Cancer Res Treat. 2007;39:61-64)