http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Hayne Cho Park ),( Young-ki Lee ),( Kyung Don Yoo ),( Hee Jung Jeon ),( Seung Jun Kim ),( Ajin Cho ),( Jacob Lee ),( Yang-gyun Kim ),( Sang-ho Lee ),( Sang-oh Lee ) 대한신장학회 2018 Kidney Research and Clinical Practice Vol.37 No.1
Patients receiving hemodialysis are vulnerable to infectious diseases due to their impaired immunity and high risk of exposure to pathogens. To protect patients, staff, and visitors from potential infections, each hemodialysis unit should establish and follow standard infection control and prevention measures. Therefore, clinical practice guidelines were developed by a working group of nephrologists and infection control specialists to provide evidence-based guidance for dialysis physicians and nurses, with the aim of preventing infection transmission and controlling infection sources in hemodialysis facilities. The areas of infection control covered by these guidelines include standard precautions, isolation strategies, vascular access, water treatment, cleaning/disinfecting/sterilizing, and vaccination. This special report summarizes the key recommendations from the Korean clinical practice guidelines for preventing the transmission of infections in hemodialysis facilities.
( Hayne Cho Park ),( Do Hyoung Kim ),( Kyung Don Yoo ),( Yang-gyun Kim ),( Sang-ho Lee ),( Hye Eun Yoon ),( Dong Ki Kim ),( Seong Nam Kim ),( Myeong Sung Kim ),( Yoon Chul Jung ),( Yon Su Kim ),( Youn 대한신장학회 2020 Kidney Research and Clinical Practice Vol.39 No.2
Coronavirus disease 2019 (COVID-19) is a highly contagious viral disease that is caused by the novel virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). COVID-19 has become pandemic since December 2019, when the first case developed in Wuhan, China. Patients receiving hemodialysis are more vulnerable to viral transmission because their immune functions are impaired and they receive treatment within a narrow space. Calling on previous experience with Middle East Respiratory Syndrome during the 2015 outbreak, the joint committee of the Korean Society of Nephrology and the Korean Society of Dialysis Therapy quickly formed a COVID-19 task force team to develop a manual before the first index case was diagnosed in the hemodialysis unit. This special article introduces clinical practice guidelines to prevent secondary transmission of COVID-19 within hemodialysis facilities, which were developed to protect patients, healthcare workers, and caregivers from this highly transmissible virus. The areas of infection control covered by these guidelines include standard precautions, performing dialysis therapy for confirmed or suspected cases, performing cohort isolation for contact patients, and disease monitoring and contact surveillance. We hope these guidelines help healthcare workers and hemodialysis patients around the world cope with the COVID-19 pandemic.
Park, Hayne Cho,Lee, Hajeong,Lee, Jung Pyo,Kim, Dong Ki,Oh, Kook-Hwan,Joo, Kwon Wook,Lim, Chun Soo,Kim, Yon Su,Ahn, Curie,Oh, Yun Kyu The Korean Academy of Medical Sciences 2012 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.27 No.1
<P>We retrospectively evaluated demographic and biochemical parameters associated with depression and health-related quality of life (HRQOL) in maintenance peritoneal dialysis (PD) patients. This study included 105 patients maintaining PD at Seoul National University Hospital. Data were collected from electronic medical record. Korean Beck's Depression Inventory and Korean version of Kidney Disease Quality of Life short form, version 1.3 were used to evaluate depression and HRQOL, respectively. Moderate to severe depression was found in 24.8% of patients. Patients with lower normalized protein equivalent of nitrogen appearance (nPNA) (< 1.2 g/kg/day), lower weekly renal Kt/V<SUB>urea</SUB> (< 0.2), and lower serum albumin level (≤ 4.0 g/dL) were associated with depression (<I>P</I> < 0.05). Among them, lower weekly renal Kt/V<SUB>urea</SUB> was the only independent risk factor associated with depression (OR = 3.1, <I>P</I> = 0.007). Depressed patients showed significantly lower scores in every dimension of HRQOL (<I>P</I> < 0.001). Lower weekly renal Kt/V<SUB>urea</SUB> (β = 0.24, <I>P</I> = 0.005) and lower nPNA (β = 0.15, <I>P</I> = 0.03) were the independent risk factors associated with lower kidney dialysis component summary, whereas lower plasma hemoglobin level was the consistent risk factor for lower physical component summary (β = 0.22, <I>P</I> = 0.03) and mental component summary (β = 0.22, <I>P</I> = 0.01). Depression is a prevalent psychological problem in PD population. Residual renal function is the most important factor associated with depression and impaired HRQOL in PD patients.</P>
( Hayne Cho Park ),( Do Hyoung Kim ),( Ajin Cho ),( Young Eun Kwon ),( Dong-ryeol Ryu ),( Jinseog Kim ),( Ki Hwa Yang ),( Ji Hyeon Shin ),( Eun Jung Son ),( Young-ki Lee ) 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.3
Background: It is important for the dialysis specialist to provide essential and safe care to hemodialysis (HD) patients. However, little is known about the actual effect of dialysis specialist care on the survival of HD patients. We therefore investigated the influence of dialysis specialist care on patient mortality in a nationwide Korean dialysis cohort. Methods: We used an HD quality assessment and National Health Insurance Service claims data from October to December 2015. A total of 34,408 patients were divided into two groups according to the proportion of dialysis specialists in their HD unit, as follows: 0%, no dialysis specialist care group, and ≥50%, dialysis specialist care group. We analyzed the mortality risk of these groups using the Cox proportional hazards model after matching propensity scores. Results: After propensity score matching, 18,344 patients were enrolled. The ratio of patients from the groups with and without dialysis specialist care was 86.7% to 13.3%. The dialysis specialist care group showed a shorter dialysis vintage, higher levels of hemoglobin, higher single-pool Kt/V values, lower levels of phosphorus, and lower systolic and diastolic blood pressures than the no dialysis specialist care group. After adjusting demographic and clinical parameters, the absence of dialysis specialist care was a significant independent risk factor for all-cause mortality (hazard ratio, 1.10; 95% confidence interval, 1.03-1.18; p = 0.004). Conclusion: Dialysis specialist care is an important determinant of overall patient survival among HD patients. Appropriate care given by dialysis specialists may improve clinical outcomes of patients undergoing HD.
Practical Issues in the Management of Polycystic Kidney Disease: Blood Pressure and Water Balance
( Hayne Cho Park ),( Yun Kyu Oh ) 대한전해질학회 2022 Electrolytes & Blood Pressure Vol.20 No.1
Autosomal dominant polycystic kidney disease is the most common hereditary renal disease affecting more than 13 million people worldwide. Renal function deteriorates as the cysts in both kidneys increase in number and size, which eventually results in end-stage kidney failure. Until recently, conservative management for chronic kidney disease such as blood pressure control, low sodium diet, adequate water intake, and weight control were known for the only treatment of polycystic kidney disease. However, the introduction of disease-modifying drug has led to the new paradigm shift in the management of polycystic kidney disease. Tolvaptan, the vasopressin V2 receptor antagonist, has been introduced to the patients with large kidneys since it can inhibit cyclic adenosine monophosphate, attenuates cyst growth, and delays renal failure. This article reviews the two important practical issues in the management of polycystic kidney disease: blood pressure and water balance. Firstly, the article will review the pathogenesis of high blood pressure in polycystic kidney disease and will demonstrate the current up-to-date management plan for blood pressure control. Secondly, this article will explain the mechanism of Tolvaptan on the treatment of polycystic kidney disease and its possible adverse effect on water and sodium balance.