Dislocation Density-Based Constitutive Model and Processing Map for T2 Copper During Isothermal and Time-Variant Deformation

Gang Chen,Yu Jin,Jing Wang,Cheng Zhang,Qiang Chen,Hongming Zhang,Xingjian Zhao,Zhiyong Li,Changhai Xie,Zhiming Du 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

Isothermal compression tests were carried out to study the hot deformation behavior of T2 copper under various conditions. The deformation parameters, such as temperature and strain rate, have strong influence on flow stress and microstructureevolution of the alloy. A unified dislocation density-based model considering dynamic recovery and recrystallization wasestablished. And material parameters of the developed model were optimized by genetic algorithm. Comparisons betweenthe experimental and model data demonstrates that the developed model can precisely describe the flow behavior at quitewide range of deformation conditions. Meanwhile, the designed iterative procedure allows the model to be applied in timevariantdeformation conditions. Processing map and microstructure examination were constructed to optimize the processingwindow of the studied alloy. According to the processing maps, flow instability mainly appeared at low temperatures of500–650 °C and strain rates higher than 0.1 s−1. The optimum deformation parameters of T2 copper was concluded as thetemperature range of 700–800 °C and the strain rate of 0.1–1 s−1.

Saliva Supernatant miR-21: a Novel Potential Biomarker for Esophageal Cancer Detection

Xie, Zi-Jun,Chen, Gang,Zhang, Xu-Chao,Li, Dong-Feng,Huang, Jian,Li, Zi-Jun Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

Objective: To identify whether saliva supernatant miR-21 can serve as a novel potential biomarker in patients with esophageal cancer (EC). Methods: 32 patients with EC and 16 healthy controls were recruited in this study. Total RNA was extracted from saliva supernatant samples for measurement of miR-21 levels using RT-qPCR and relationships between miR-21 levels and clinical characteristics of EC patients were analyzed. Results: miR-21 was significantly higher in the EC than control groups. The sensitivity and specificity were 84.4% and 62.5% respectively. Supernatant miR-21 levels showed no significant correlation with cancer stage, differentiation and nodal metastasis. Conclusions: Saliva supernatant miR-21 may be a novel biomarker for EC.

Characterization, Cloning, and Heterologous Expression of a Subtilisin-Like Serine Protease Gene VlPr1 from Verticillium lecanii

Gang Yu,Jin-Liang Liu,Li-Qin Xie,Xue-Liang Wang,Shi-Hong Zhang,Hong-Yu Pan 한국미생물학회 2012 The journal of microbiology Vol.50 No.6

The entomopathogenic fungus Verticillium lecanii is a wellknown biocontrol agent. V. lecanii produces subtilisin-like serine protease (Pr1), which is important in the biological control activity of some insect pests by degrading insect cuticles. In this study, a subtilisin-like serine protease gene VlPr1 was cloned from the fungus and the VlPr1 protein was expressed in Escherichia coli. The VlPr1 gene contains an open reading frame (ORF) interrupted by three short introns, and encodes a protein of 379 amino acids. Protein sequence analysis revealed high homology with subtilisin serine proteases. The molecular mass of the protease was 38 kDa, and the serine protease exhibited its maximal activity at 40°C and pH 9.0. Protease activity was also affected by Mg2+ and Ca2+ concentration. The protease showed inhibitory activity against several plant pathogens, especially towards Fusarium moniliforme.

An Electric-Field Coupled Power Transfer System with a Double-sided LC Network

Xie, Shi-Yun,Su, Yu-Gang,Zhou, Wei,Zhao, Yu-Ming,Dai, Xin The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.1

Electric-field coupled power transfer (ECPT) systems employ a high frequency electric field as an energy medium to transfer power wirelessly. Existing ECPT systems have made great progress in terms of increasing the transfer distance. However, the topologies of these systems are complex, and the transfer characteristics are very sensitive to variations in the circuit parameters. This paper proposes an ECPT system with a double-sided LC network, which employs a parallel LC network on the primary side and a series LC network on the secondary side. With the same transfer distance and output power, the proposed system is simpler and less sensitive than existing systems. The expression of the optimal driving voltage for the coupling structure and the characteristics of the LC networks are also analyzed, including the transfer efficiency, parameter sensitivity and total harmonic distortion. Then, a design method for the system parameters is provided according to these characteristics. Simulations and experiments have been carried out to verify the system properties and the design method.

Scaffold Engineering with Flavone-Modified Biomimetic Architecture for Vascular Tissue Engineering Applications

Xie Chao,Guo Ting,Wang Wei,Li Gang,Cai Zhou,Chen Shen,Wang Xianwei,Liu Ziyu,Wang Zuyong 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.4

BACKGROUND: Vascular intimal hyperplasia (IH) is one of the key challenges in the clinical application of smalldiameter vascular grafts. Current tissue engineering strategies focus on vascularization and antithrombotics, yet few approaches have been developed to treat IH. Here, we designed a tissue-engineered vascular scaffold with portulaca flavonoid (PTF) composition and biomimetic architecture. METHOD: By electrospinning, PTF is integrated with biodegradable poly(e-caprolactone) (PCL) into a bionic vascular scaffold. The structure and functions of the scaffolds were evaluated based on material characterization and cellular biocompatibility. Human vascular smooth muscle cells (HVSMCs) were cultured on scaffolds for up to 14 days. RESULTS: The incorporation of PTF and preparation parameters during fabrication influences the morphology of the scaffold, including fibre diameter, structure, and orientation. Compared to the PCL scaffold, the scaffolds integrated with bioactive PTF show better hydrophilicity and degradability. HVSMCs seeded on the scaffold alongside the fibres exhibit fusiform-like shapes, indicating that the scaffold can provide contact guidance for cell morphology alterations. This study demonstrates that the PCL/PTF (9.1%) scaffold inhibits the excessive proliferation of HVSMCs without causing cytotoxicity. CONCLUSION: The study provides insights into the problem of restenosis caused by IH. This engineered vascular scaffold with complex function and preparation is expected to be applied as a substitute for small-diameter vascular grafts.

Comparative Effectiveness of Risk-adapted Surveillance vs Retroperitoneal Lymph Node Dissection in Clinical Stage I Nonseminomatous Germ Cell Testicular Cancer: A Retrospective Follow-up Study of 81 Patients

Fan, Gang,Zhang, Lin,Yi, Lu,Jiang, Zhi-Qiang,Ke, Yang,Wang, Xiao-Shan,Xiong, Ying-Ying,Han, Wei-Qin,Zhou, Xiao,Liu, Chun,Yu, Xie Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

Purpose: To retrospective assess the potential predictors for relapse and create an effective clinical mode for surveillance after orchidectomy in clinical stage I non-seminomatous germ cell testicular tumors (CSI-NSGCTs). Materials and Methods: We analyzed data for CSI-NSGCTs patients with non-lymphatic vascular invasion, %ECa < 50% (percentage of embryonal carcinoma < 50%), and negative or declining tumor markers to their half-life following orchidectomy (defined as low-risk patients); these patients were recruited from four Chinese centers between January 1999 and October 2013. Patients were divided into active surveillance group and retroperitoneal lymph node dissection (RPLND) group according to different therapeutic methods after radical orchidectomy was performed. The disease-free survival rates (DFSR) and overall survival rates (OSR) of the two groups were compared by Kaplan-Meier analysis. Results: A total of 121 patients with CSI-NSGCT were collected from four centers, and 81 low-risk patients, including 54 with active surveillance and 27 with RPLND, were enrolled at last. The median follow-up duration was 66.2 (range 6-164) months in the RPLND group and 65.9 (range 8-179) months in the surveillance group. OSR was 100% in active surveillance and RPLND groups, and DFSR was 89.8% and 87.0%, respectively. No significant difference was observed between these two groups ($X_2=0.108$, P=0.743). No significant difference was observed between the patients with a low percentage of embryonal carcinoma (<50%) and those without embryonal carcinoma (87.0% and 91.9%, $X_2=0.154$, P=0.645). No treatment-related complications were observed in the active surveillance group whereas minor and major complications were observed in 13.0% and 26.1% of the RPLND group, respectively. Conclusions: Active surveillance resulted in similar DFSR and OSR compared with RPLND in our trial. Patients with low-risk CSI-NSGCTs could benefit from risk-adapted surveillance after these patients were subjected to radical orchidectomy.

Expression and Underlying Roles of IGFBP-3 in Paclitaxel-Treated Gastric Cancer Sgc-7901 Cells

Huang, Gang,Dang, Zhong-Feng,Dang, Ya-Mei,Cai, Wei,Li, Yuan,Chen, Yi-Rong,Xie, Xiao-Dong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

Purpose: To study the expression of insulin-like growth factor binding proteins (IGFBPs) in paclitaxel-treated gastric cancer SGC-7901 cells, and to further investigate underlying mechanisms. Materials and Methods: Real time PCR and Western blot assays were applied to detect the mRNA and protein expression of IGFBP-2, -3 and -5 after paclitaxel (10 nM) treatment of SGC-7901 cells. In addition IGFBP-3 expression was silenced by RNA interference to determine effects. Cell viability was determined by MTT assay. Cell cycling and apoptosis were assessed by flow cytometry. Results: Compared to the control group, only IGFBP-3 expression was elevated significantly after paclitaxel (10 nM) treatment (p<0.05). Paclitaxel treatment caused cell cycle arrest and apoptosis via downregulating Bcl-2 expression. However, the effect could be abrogated by IGFBP-3 silencing. Conclusions: IGFBP-3 exhibits anti-apoptotic effects on paclitaxel-treated SGC-7901 cells via elevating Bcl-2 expression.

Biochar Can Mitigate Farmland Global Warming Potential and Remediate Pops Polluted Soil

Zubin Xie,Yanping Xu,Georg Cadisch,James Amonette,Jianguo Zhu,Gang Liu 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

예술제 개최지 및 기원지에 따른 개최효과 차이분석

사염이(Xie, YanYi),정강환(Jeong, Gang-Hoan),호정(Hu, Ting) 한국문화산업학회 2014 문화산업연구 Vol.14 No.4

최근에 들어 예술제의 산업화에 따라 예술제를 주관하는 지방자치단체들이 지역축제라는 마케팅 수단을 동원하여 시민들의 여가 수요를 수용하고 있으며 재정보조와 가격할인 등 수단을 통해 더 많은 시민이 예술제의 각종 활동에 참여하게 한다. 따라서 본 연구는 중국오교서커스예술제에 대한 분석을 통하여 예술제 개최지 및 기원지에 따른 개최효과를 규명하고자 하였으며 전통 문화를 소재로 한 예술이벤트를 개최할 때 벤치마킹할 수 있는 참고자료로 활용하는 데 목적으로 두었다. 이를 위해 본 연구는 축제개최효과에 관련된 선행연구를 바탕으로 축제개최효과의 하위차원을 도출한 후 이 요인들에 대해 T-test를 실시하였다. 실증 분석결과 관광효과와 경제효과에 있어 개최지인 석가장과 기원지인 오교 간의 차이가 있는 것으로 나타났다. 이러한 연구결과는 축제개최효과에 관한 연구에 이론적 시사점을 제공할 뿐만 아니라 오교국제서커스예술제를 운영하는 정부 및 기업에게 실무적 시사점도 제공해 줄 수 있다. The impacts of festival have been identified by researchers. Festival as a tourism product plays an important role in local development including economic, tourism, social and cultural development. But for some festivals, such as art festival, its host city may differ from the original city of art. The study aims to compare if the impacts of the art festival would be different from the host city and the original city of the art. In order to achieve the objectives of the study, the survey was carried out. 348 questionnaires were used in the analysis including 202 from the host city and 146 from the original city of the art. As a result, significant differences were found from the two areas, especially in economic impacts and tourism impacts. The host city had more economic impacts compared to the original city of the art, while the original city of the art had more tourism impacts than the host city. Based on the results, some implications were proposed to the both host city and the original city of the art to enhance the positive impacts of the festival. 최근에 들어 예술제의 산업화에 따라 예술제를 주관하는 지방자치단체들이 지역축제라는 마케팅 수단을 동원하여 시민들의 여가 수요를 수용하고 있으며 재정보조와 가격할인 등 수단을 통해 더 많은 시민이 예술제의 각종 활동에 참여하게 한다. 따라서 본 연구는 중국오교서커스예술제에 대한 분석을 통하여 예술제 개최지 및 기원지에 따른 개최효과를 규명하고자 하였으며 전통 문화를 소재로 한 예술이벤트를 개최할 때 벤치마킹할 수 있는 참고자료로 활용하는 데 목적으로 두었다. 이를 위해 본 연구는 축제개최효과에 관련된 선행연구를 바탕으로 축제개최효과의 하위차원을 도출한 후 이 요인들에 대해 T-test를 실시하였다. 실증 분석결과 관광효과와 경제효과에 있어 개최지인 석가장과 기원지인 오교 간의 차이가 있는 것으로 나타났다. 이러한 연구결과는 축제개최효과에 관한 연구에 이론적 시사점을 제공할 뿐만 아니라 오교국제서커스예술제를 운영하는 정부 및 기업에게 실무적 시사점도 제공해 줄 수 있다. The impacts of festival have been identified by researchers. Festival as a tourism product plays an important role in local development including economic, tourism, social and cultural development. But for some festivals, such as art festival, its host city may differ from the original city of art. The study aims to compare if the impacts of the art festival would be different from the host city and the original city of the art. In order to achieve the objectives of the study, the survey was carried out. 348 questionnaires were used in the analysis including 202 from the host city and 146 from the original city of the art. As a result, significant differences were found from the two areas, especially in economic impacts and tourism impacts. The host city had more economic impacts compared to the original city of the art, while the original city of the art had more tourism impacts than the host city. Based on the results, some implications were proposed to the both host city and the original city of the art to enhance the positive impacts of the festival.

NUMERICAL STUDY ON THE VORTEX STRUCTURES OF AN OSCILLATING CIRCULAR CYLINDER IN UNIFORM FLOWS

Bing Gang Tong,Xie Yuan Yin,Xi Yun Lu 대한기계학회 1992 International Conference on Fluid Machinery Vol.1 No.1