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      • 밀리미터파를 이용한 무혈 혈당 측정에 관한 기초 연구

        Kim Dong Kyun,Won Jong Hwa,Potapov Sergey N.,Meriakri Viacheslav V.,Chigryai Evgenii E. 대한전자공학회 2005 電子工學會論文誌-SC (System and control) Vol.42 No.1

        As a basic research for the development of a non-invasive blood glucose sensor using millimeter waves, we have presented a method for measuring the dielectric properties of high loss dielectrics, based on the reflection method, and investigated the variation of the dielectric properties of glucose-water and glucose -0.9% NaCl solutions in the 10~90 GHz range. In the proposed method, a minimal reflection condition is formed by placing a specially-chosen low-loss plane-parallel plate in front of a high-loss medium under test at a given frequency range. Using the minimal power reflection coefficient and the corresponding frequency at this condition, tile dielectric properties of the medium can be determined. The measured results on pure water have shown the adequacy of the proposed method. The measured results on glucose-water and glucose -0.9% NaCl solutions in the 10~90 GHz range showed that the variations of the dielectric properties of glucose solutions according to the change of their glucose concentration were maximum in the 30~45 GHz range. From these facts we concluded that the variation of about 3 mole/L in the glucose solutions must be distinguished With the measurement accuracies of ±0.1 dB and ±0.01 GHz. 본 논문은 밀리미터파를 이용한 무혈혈당측정기 개발의 기초연구로서, 높은 유전손실을 지닌 유전체의 반사 유전특성 측정법을 제시하고, 이에 의해 10~90 GHz의 밀리미터파 대역에서 글루코오스 농도에 따른 글루코오스 수용액 및 글루코오스 -0.9% NaCl 용액의 유전특성 변화를 조사하였다. 제시된 측정법은 측정 유전제의 앞단에 평행평면판을 배치하여 측정 주파수대역 내에서 전력반사계수가 최소가 되는 최소반사조건이 형성되도록 하고, 이 조건에서 측정된 최소 전력반사계수와 주파수로부터 측정 유전체의 유전특성을 결정할 수 있는 방법이다. 순수의 유전특성에 대한 측정 결과들은 제시된 측정법의 타당성을 입증하였다. 또한 10~90 GHz 대역에서 글루코오스 농도 변화에 따른 글루코오스 용액 및 글루코오스 -0.9% NaCl 용액들의 유전특성 변화에 대한 실험을 통해, 타 대역에 비해 30~45 GHz 범위에서 글루코오스 농도 변화에 의한 각 용액들의 유전특성의 변화가 최대임을 알 수 있었다. 이를 통해 본 측정법에서 전력반사계수와 주파수의 측정 정밀도가 각각 ±0.1 dB와 ±0.01 GHz일 경우, 대략 3 mole/L 정도의 분해능으로 용액 내 글루코오스 농도 변화를 측정할 수 있음을 보였다.

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        The Dynamics of the K-Pop Boom in Russia

        Evgenii Smagin,Ik Ki Kim,Wonho Jang 지역사회학회 2015 지역사회학 Vol.16 No.2

        This research reviews the current situation of the Korean wave in Russia and tries to explain the dynamics of the development of K-pop in Russia. To do so, in-depth interviews of six young Russians who have experienced the Korean Wave were conducted. The contents of the in-depth interviews include familiarity with Korean culture, definition of the Korean Wave, the influences of the Korean Wave on Russian society, and the appeal of K-Pop. In addition, the development of K-Pop in Russia is reviewed focusing on the change of participants in K-Pop fan clubs. A very rapid increasing number of the fan clubs and internet communities for Korean K-pop groups was observed. The number of participants in most fan clubs reviewed increased four times in the previous three years. K-Pop web sites and magazines also increased rapidly in terms of members and contents, playing an important role in the development of K-Pop. The paper suggests explanations for the recent boom of K-pop in terms of background factors and the attractions of K-pop itself. Excellent performances and hybridity are raised as key factors regarding attraction to K-Pop. Concerning background factors, YouTube with the recent developments in internet access and smart phone usage play a crucial role in the spread of K-pop in Russia.

      • KCI등재

        Preliminary Study of Gender-Based Brain Lateralization Using Multi-Channel Near-Infrared Spectroscopy

        Zephaniah Phillips V,김재관,Evgenii Kim 한국광학회 2015 Current Optics and Photonics Vol.19 No.3

        It has been thought that males tend to use their brain hemispheres more laterally than females. However,recent fMRI studies have shown that there may be no difference in brain lateralization between genders. Functional near-infrared spectroscopy (fNIRS) presents a unique opportunity to acquire real timemeasurements of blood oxygenation changes to observe neural activity specific to the brain’s left and righthemispheres. Using an in-house built multichannel fNIRS system, brain lateralization was observed fromseven males and four females according to specially designed tasks for left and right hemisphere activation. The Pearson correlation coefficient and a modified Lateralization Index metric for continuous wave fNIRSsystems were calculated to quantify brain lateralization. The preliminary results point to no significantdifference in lateral hemodynamic changes between the genders. However, the correlation of symmetricalchannel pairs decreased as the experiments progressed. To further develop this study, the subject’s performanceand the removal of global interference must be implemented for an improved study of brain lateralization

      • KCI등재

        Evaluation of advective solute infiltration into porous media by pulsed focused ultrasound-induced acoustic streaming effects

        Jared Van Reet,Kate Tunnell,Kara Anderson,Hyun-Chul Kim,Evgenii Kim,Kavin Kowsari,Yoo Seung-Schik 대한초음파의학회 2024 ULTRASONOGRAPHY Vol.43 No.1

        Purpose: Acoustic streaming induced by applying transcranial focused ultrasound (FUS) promotes localized advective solute transport in the brain and has recently garnered research interest for drug delivery and enhancement of brain waste clearance. The acoustic streaming behavior in brain tissue is difficult to model numerically and thus warrants an in vitro examination of the effects of using different sonication parameters, in terms of frequency, intensity, and pulse duration (PD). Methods: Melamine and polyvinyl alcohol (PVA) foams were used to mimic the porous brain tissue, which contains leptomeningeal fenestrations and perivascular space, while agar hydrogel was used to emulate denser neuropil. FUS was delivered to these media, which were immersed in a phosphate-buffered saline containing toluidine blue O dye, across various frequencies (400, 500, and 600 kHz; applicable to transcranial delivery) in a pulsed mode at two different spatial- peak pulse-average intensities (3 and 4 W/cm2). Results: Image analysis showed that the use of 400 kHz yielded the greatest dye infiltration in melamine foam, while sonication had no impact on infiltration in the agar hydrogel due to the dominance of diffusional transport. Using a fixed spatial-peak temporal-average intensity of 0.4 W/cm2 at 400 kHz, a PD of 75 ms resulted in the greatest infiltration depth in both melamine and PVA foams among the tested range (50-150 ms). Conclusion: These findings suggest the existence of a specific frequency and PD that induce greater enhancement of solute/fluid movement, which may contribute to eventual in vivo applications in promoting waste clearance from the brain. Purpose: Acoustic streaming induced by applying transcranial focused ultrasound (FUS) promotes localized advective solute transport in the brain and has recently garnered research interest for drug delivery and enhancement of brain waste clearance. The acoustic streaming behavior in brain tissue is difficult to model numerically and thus warrants an <i>in vitro</i> examination of the effects of using different sonication parameters, in terms of frequency, intensity, and pulse duration (PD).Methods: Melamine and polyvinyl alcohol (PVA) foams were used to mimic the porous brain tissue, which contains leptomeningeal fenestrations and perivascular space, while agar hydrogel was used to emulate denser neuropil. FUS was delivered to these media, which were immersed in a phosphate-buffered saline containing toluidine blue O dye, across various frequencies (400, 500, and 600 kHz; applicable to transcranial delivery) in a pulsed mode at two different spatialpeak pulse-average intensities (3 and 4 W/cm<sup>2</sup>).Results: Image analysis showed that the use of 400 kHz yielded the greatest dye infiltration in melamine foam, while sonication had no impact on infiltration in the agar hydrogel due to the dominance of diffusional transport. Using a fixed spatial-peak temporal-average intensity of 0.4 W/cm2 at 400 kHz, a PD of 75 ms resulted in the greatest infiltration depth in both melamine and PVA foams among the tested range (50-150 ms).Conclusion: These findings suggest the existence of a specific frequency and PD that induce greater enhancement of solute/fluid movement, which may contribute to eventual in vivo applications in promoting waste clearance from the brain.

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