진화알고리즘과 퍼지시스템을 이용한 단기부하예측 시스템개발에 관한 연구

張右晳,李性穆,姜渙一 명지대학교 산업기술연구소 2006 産業技術硏究所論文集 Vol.25 No.-

This paper proposes a time series prediction method for the nonllinear system using the fuzzy system and the evolutionay strategy and the genetic algorithm. At first, we obtain the optimal fuzzy membership function using the evolutionary strategy or genetic algorithm. With the optimal fuzzy rules and its input differences, a better time prediction series system may be obtained. We obtain a good result for the time prediction of the short term electric load. In addition we implement the graphic user interface for the proposed algorithms.

퍼지시스템과 진화알고리즘 기반 지역부하예측 시스템개발

張右晳,指眩旻,姜渙一 명지대학교 산업기술연구소 2006 産業技術硏究所論文集 Vol.25 No.-

This paper proposes a time series prediction method for the nonlinear system using the fuzzy system and the evolutionay strategy and the genetic algorithm. At first, we obtain the optimal fuzzy membership function using the evolutionary strategy or genetic algorithm. With the optimal fuzzy rules and its input differences, a better time prediction series system may be obtained. We obtain a good result for the time prediction of the regional electric load. In addition we implement the graphic user interface for the proposed algorithms.

온라인 화상 인증을 위한 분산 객체 활성화 시스템

허진경,양환석,박승규,장근실,김종민 朝鮮大學校 統計硏究所 2007 統計硏究所論文誌 Vol.9 No.1

클라이언트로부터 전송되는 인증 데이터를 실시간으로 서버에서 분석하여 처리하는 시스템의 경우에는 입력되는 데이터의 양에 비례하여 서버의 부담은 증가하게 된다. 이때 서버에서는 데이터의 병목현상이 발생하게 되고, 이는 바로 전체적인 시스템의 성능을 저하시키는 결과를 초래하게 된다. 본 논문에서는 데이터 처리의 병목현상을 해결하여 시스템의 성능을 높일 뿐만 아니라, 인터넷상의 유휴 서버들을 활용할 수 있게 하기 위한 방안으로 분산처리 기술을 이용한 전처리 작업 시스템과 그 성능을 향상시키기 위한 분산 객체 활성화 시스템을 제안한다.

자동차용 실리콘 가속도센서의 개발(Ⅱ)

이종현,신장규,이상룡,천희곤,조찬섭,심준환,류인식,박석홍,허정준,박기열 경북대학교 센서기술연구소 1994 연차보고서 Vol.1994 No.-

자동차의 air-bag 장치에 실용될 수 있는 압저항형 단결정 실리콘 가속도센서 칩을 개발하기 위하여 결정 실리콘 미세구조의 제조방법을 확립하고, 단위공정의 검증을 통하여 일괄공정에 의한 PROTO-TYPE 칩을 만드는 기술을 연구하였다. 단결정 실리콘 미세구조는 선택확산법을 이용하여 정확히 선택된 영역에만 air-gap을 형성하여 미세구조의 측면식각을 방지하는 선택확산법에 의한 실리콘 마이크로머시닝 기술로 제조하였다. 일괄공정을 위한 단위공정확립을 위하여 PROTY-TYPE 8빔 브릿지형 가속도 센서를 제조하였다. 제조된 칩의 가속도에 따른 출력전압은 선형성을 나타내고 있으며, 감도는 약 50 ㎶/V·g로 나타났다. 이 감도는 50G용 가속도센서의 사양을 만족하지 못했다. 이는 공정에 의한 문제라기 보다는 가속도센서의 시뮬레이션에 의해 설계한 구조가 이미 원하는 감도에 못 미친다는 것으로 생각된다. 따라서 2차 공정으로 제조될 가속도센서의 파라미터를 SuperSAP 유한요소 패키지를 이용하여 실리콘 미세구조부의 파라미터에 따른 특성을 시뮬레이션하였다. 설계된 50G용 가속도센서의 mass Pad의 반경 및 빔 길이, 빔 폭, 빔 두께, 그리고 mass의 각 파라미터 값은 700 ㎛, 120 ㎛, 5 ㎛, 1.0 ㎎ 이었다. 반도체 공정기술, 관성질량 제조법 및 선택확산을 이용한 마이크로머시닝을 사용하여 일괄공정으로 8빔 브린지형 가속도센서를 제조하였다. We researched the establishment of the silicon microstructure fabrication technique to develop a piezoresistive type silicon acceleration sensor chip and the technique to make a proto-type chip by the verification of the unit-process. Silicon microstructure is fabricated silicon micro-machining by selective diffusion method. This method prevent a side-etching of microstructure because selective diffused region is only formed an air-gap. We fabricated a proto-type 8-beam bridge-type acceleration sensor to establish the unit-process for the batch-process. The output voltage of the chip represented linearity with acceleration, and the sensitivity was about 50 ㎶/V·g. But this sensitivity dosen't satisfy the requirements of a practical acceleration sensor. The cause of this result is assumed not process problem, but the structure designed by simulation isn't suitable already. Threfore, the characteristics of parameters of the acceleration sensor that will be fabricated by 2nd-process is simulated by SuperSAP finite-element package. The determined parameter values of beam length, beam width, beam thickness, mass, and mass radius are 120 ㎛, 5 ㎛, 1.0 ㎎, and 700 ㎛, respectively. We fabricated 8-beam bridge-type acceleration sensor by batch-process using a semiconductor process technique, proof-mass fabrication method, and micromachinig using selective diffusion.

손가락 끝 점을 이용한 손 형상 인식

김종민,이웅기,장근실,양환석,허진경,박승규 朝鮮大學校 統計硏究所 2007 統計硏究所論文誌 Vol.9 No.1

최근 사용자 친화형 유저 인터페이스 구현을 위해 인간의 손 형상을 실시간으로 인식하는 연구의 중요성이 부각되고 있다. 그러나 인간의 손은 자유도가 크기 때문에 손 형상을 정확히 인식하기란 매우 어렵고 또한 피부색과 유사한 색을 가지는 복잡한 배경에서는 더욱 곤란하다. 본 논문에서는 별도의 센서를 부착하지 않고 카메라를 사용하여 피부색 정보에 의한 손 형상을 분할한 후 손가락 끝 점을 찾는다. 찾은 손가락 끝 점을 이용하여 방향을 탐지하는 알고리즘에 대해 기술한다. 이 방법은 템플리트 매칭을 이용하여 손가락 끝 점을 탐색한 후 찾은 손가락 끝 점과 손목의 중심을 이용하여 전, 후, 좌, 우 방향을 탐지한다. 제안하는 방법을 이용하여 3D 가상현실 공간에서의 네비게이션(Navigation)에 응용하였으며, 실험결과 전진, 후진 및 좌측, 우측의 방향전환도 매우 좋은 결과를 보였다. 또한 본 논문에서 제안하는 방법은 마우스, 키보드, 조이스틱 등의 조작 없이 전, 후, 좌, 우 방향전환을 사용자가 직관적으로 지시함으로써 보다 자연스러운 인간과 컴퓨터의 상호작용을 제공할 수 있을 것이다.

새로운 방법에 의한 1,1-R,R'-2,3,4,5-테트라페닐-1-실라사이크로펜타디엔의 합성

주완철,흥장환,최석봉 성균관대학교 기초과학연구소 1988 論文集 Vol.39 No.1

A new synthesis of 1,1-R, R',-2, 3, 4, 5-tetraphenyl-1-silacyclopentadiene was described. It was synthesized from one-pot reaction of 1,4-dilithio-1, 2, 3, 4-tetraphenylbutadiene with R_nSiCl_4-n (n=0, 1, 2), where 1, 4-dilithio-1, 2, 3, 4-tetraphenyl butadiene was prepared from the reaction of diphenyl acetylene and lithium metal in ether solution with good yield (80∼85%).

Symplastic glomus tumor 1예

이원채,장윤환,김효진,이석종,정상립,이수경,배한익 대한피부과학회 2003 대한피부과학회지 Vol.41 No.8

Glomus tumor is a benign lesion characterized by vessels and glomus cells in the varying proportion and it classically presents as a solitary, painful papule or nodule. Occasionally it displays unusual histopathologic features diagnosed as "atypical" glomus tumor, including malignant glomus tumor, glomus tumor of uncertain malignant potential, glomangiomatosis, and symplastic glomus tumor. Glomangiomatosis and symplastic glomus tumor reveal benign biologic behavior. We report herein a typical case of symplastic glomus tumor showing marked nuclear atypia, its only unusual feature comparing with classical one, in addition to the typical clinical and pathological features. (Korean J Dermatol 2003;41(8) : 1118~1120)

족삼리 침자극의 복통 억제기전 연구

임사비나,임형택,박히준,장지련,최일환,이석찬,김대수,신희섭 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : Acupuncture has been used for treatment of numerous disorders, especially for pain control in Oriental Medicine. However, the mechanism of pain control by acupuncture was not clear until now. This study was performed to prove analgesic mechanism of acupuncture treatment at acupoint ST_(36) by observing the changes of abdominal pain and c-Fos expression in the thalamus. Methods : Abdominal pain was induced by acetic acid, and the changes of writhing reflex after acupuncture treatment an ST_(36) and non-acupoints were measured. c-Fos immunohistochemistry was also performed to study the changes of the neuronal activity in the thalamus. Results : The writhing reflex decrease significantly after acupuncturing at ST_(36) compared with control group(p<0.05). The changes of the writhing reflex by non-acupoint acupuncture treatment also showed significant decrease compared with control group(p<0.05). c-Fos expression in the thalamus, especially periventricular part was significantly decreased after acupuncturing at ST_(36) compared with control groups(p<0.05). Conclusion : This study shows that the acupuncture has the analgesic effect in the abdominal pain induced by acetic acid and the thalamus might be a important area for this mechanism.

Effect of renin-angiotensin system blockade in patients with severe renal insufficiency and heart failure

Jang, Se Yong,Chae, Shung Chull,Bae, Myung Hwan,Lee, Jang Hoon,Yang, Dong Heon,Park, Hun Sik,Cho, Yongkeun,Cho, Hyun-Jai,Lee, Hae-Young,Oh, Byung-Hee,Choi, Jin-Oh,Jeon, Eun-Seok,Kim, Min-Seok,Lee, San Elsevier 2018 INTERNATIONAL JOURNAL OF CARDIOLOGY Vol.266 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Renin-angiotensin system blockade (RAB) is the cornerstone in the management of patients with heart failure. However, the benefit of RAB in patients with accompanying severe renal impairment is not clear. We aimed to examine the effect of RAB and the differential effect of RAB depending on renal replacement (RR) in patients with severe renal insufficiency and acute heart failure.</P> <P><B>Methods and Results</B></P> <P>Among 5625 patients from the Korean Acute Heart Failure registry, 673 in-hospital survivors (70.9 ± 12.8 years, 376 men) who had left ventricular ejection fraction < 40% and estimated glomerular filtration rate < 30 mL/min/1.73 m<SUP>2</SUP> during hospitalization were analyzed. The inverse probability of treatment weighting (IPTW)-adjusted survival analysis was used to compare the composite of all-cause mortality and rehospitalization between patients with and without pre-discharge RAB. A total of 334 (49.6%) adverse events were observed during the 1-year follow-up. The IPTW-adjusted Kaplan-Meier survival analysis showed that the 1-year event rate was 48.7% and 53.8% for patients with RAB and those without, respectively (log rank p = 0.048). RAB was significantly related to better prognosis in patients receiving RR therapy (hazard ratio [HR] = 0.436 [0.269–0.706], p = 0.001), but not in patients not receiving RR therapy (HR 0.956 [0.731–1.250], p = 0.742) in a weighted cohort (p for interaction = 0.005).</P> <P><B>Conclusions</B></P> <P>Early RAB treatment in patients with heart failure and severe renal insufficiency was related to better prognosis. The benefit of RAB was particularly prominent in patients receiving RR therapy.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Renin-angiotensin blockade (RAB) was associated with favorable prognosis. </LI> <LI> RAB was more effective in patients with renal replacement therapy (RR). </LI> <LI> Patients with RR were taking higher intensity of RAB at 1-year follow-up. </LI> </UL> </P>

FCT 6 : Intradermal tacrolimus injection in refractory alopecia totalis

( Seok Hwan Jang ),( Jee Bum Lee ),( Seung Chul Lee ),( Young Ho Won ),( Seong Jin Kim ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.1

Calcineurin inhibitor tacrolimus is known as highly effective immunosuppressant preventing acute rejection after organ transplantation by inhibiting T lymphocyte activation and IL-2. Topical tacrolimus has been tried in many reports in the treatment of alopecia areata, but the results have not been encouraging. However, some reports described rapid hair regrowth in a patient with alopecia totalis after organ transplantation following systemic tacrolimus therapy. We speculated the treatment failure of topical tacrolimus may be related to inefficient drug delivery, thus intradermal tarcrolimus injection could be an alternative therapeutic approach to refractory alopecia totalis. A 45-year-old man of alopecia totalis had been treated with oral cyclosporine, intralesional injection of TA, and topical immunotherapy with DPCP for 3 years, but failed to get recover any hair growth. With given information on the trial of intralesional tacrolimus, the patient agreed to receive this treatment with formal consent. We calculated optimum dosage for immunosuppressive effects, considering body surface area, and treated Rt. side of scalp with 10ml of intradermal injection of tacrolimus(0.05mg/ml) every week. But, after 4 months of treatment, no vellus hair growths was noted as well as no visible side-effect on injected area. Though it`s an anecdotal clinical trial, our result did not confirmed a favorable effect by intradermal tacrolimus injection.