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조용재,김승범,진동규,서의교,김상진 대한척추신경외과학회 2004 Neurospine Vol.1 No.1
Objectives: Symptoms arising from spinal cord tumor are often insidious in onset and nonspecific in nature. To make the subtle initial signs and symptoms of these tumors more apparent to clinicians, we retrospectively analyzed the data of spinal cord tumor patients who were misdiagnosed as degenerative spine disease. Methods: We reviewed history, symptom, sign, radiological study, and pathologic diagnosis of 19 spinal cord tumor patients who had been operated as degenerative spine disease, especially duration and description of symptoms and sign before an accurate diagnosis was made. Results: Average duration of delay before an accurate diagnosis was made was 178.4 days(range: 23~303). Common symptom and signs on neurologic examination included aggravation of pain(8 cases; 47.1 %), and neurologic decline(9 cases; 52.9%) The misdiagnosis included a herniated lumbar disc(16 cases; 94.1%), lumbar stenosis(1 case; 5.9%). Inappropriate treatment for these misdiagnoses included 5 percutaneous lazer discectomies, 9 discectomies, 3 chemonucleolysis, 2 posterior lumbar interbody fusions with cages. Conclusion: When a patient has symptoms that appear to be out of the ordinary, surgeons should suspect other spinal disease including the spinal cord tumor.
치아우식증 수복용 복합레진의 개발과 치아 적합성에 관한 연구 제 3 편 : 각종 용액내에서의 표면경도 변화와 세포독성에 관한 연구
최유진,조한국,민병순 大韓齒科器材學會 1992 대한치과재료학회지 Vol.19 No.2
This studies were planned to evaluate the cytotoxicity of cured experimental composite resin using a cell culture method, and the hardness changes of it stored in various aqueous acids and ethanol with considerations that solubility of resin surfaces will occure the decrease of hardness should be related with toxicity occured by elucited components. Cytotoxicity of experimental resins were tested by agar overlay methods, and some solutions in which disc type resin specimens will be stored were prepared by dilution of ethanol or acids into distilled water. The microhardness of experimental and commercial dental restorative composite materials exposed to various chemicals were measured with micro Vicker's hardness tester. Following conclusions were drawn : 1. KCR-22, experimental composite resins prepared in this study exhibited the same degree of cytotoxicity with commercial products. 2. The intensity of cytotoxicity decreased after incorporation of filler to BIS-GMA based resins. 3. The hardness numbers decreased dramatically once the composite had been immersed in ethanol solutions, however any of acidic solutions did not show the decrease of VHN. 4. The incorporation of fillers to BIS-GMA based resins which showed the double increased VHN than unfilled resins. 5. Surface hardness were increased rapidly in saline compared to it in air.
Case Report : Breast Cancer Cutaneous Metastasis at Core Needle Biopsy Site
( Eu Jin Cho ),( Min Ho Kim ),( Sang Hee Cha ),( Sang Hyun Cho ),( Se Jeong Oh ),( Jeong Deuk Lee ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.2
Cutaneous metastasis from breast cancer can occur by direct invasion, lymphatic and vascular spread as well as iatrogenic implantation. Metastasis that occurs by iatrogenic implantation after needle biopsy is very rare but the potential risk must be considered. In this report, we describe a case of breast cancer cutaneous metastasis that occurred by iatrogenic implantation following core needle biopsy. A 53-year-old woman presented with a 1×1 cm sized erythematous nodule at the biopsy site after breast conserving surgery for primary cancer. Histopathological findings confirmed cutaneous metastasis. The possibility of this consequence must be considered when performing needle biopsies. (Ann Dermatol 22(2) 238~240, 2010)
JIN, Guang-Zhen,YIN, Xi-Jun,YU, Xian-Feng,CHO, Su-Jin,CHOI, Eu-Gene,LEE, Young-S,JEON, Jin-Tae,YEE, Sung-Tae,KONG, Il-Keun Japanese Society of Veterinary Science 2008 The Journal of veterinary medical science Vol.70 No.7
<P>Umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) are multipotent adult stem cells, which can differentiation into cells of connective tissue and neural lineages. This study investigated the potential for neuronal differentiation of red fluorescent protein (RFP)-transgenic cat UCB-derived MSCs. The cells were cultured in pre-induction medium for 24 hr and in neuronal-induction medium for 72 hr. Immunofluorescent staining showed that 6.85% of the total cells were β III-tubulin-positive, 3.37% were neurofilament light (NF-L)-positive and 7.04% were neurofilament medium (NF-M)-positive. A β III-tubulin band was detected by western blot analysis. Our results demonstrate that RFP-transgenic UCB-derived MSCs can be differentiated into neuronal cells <I>in vitro</I>. Thus, RFP-transgenic MSCs could provide alternative tracing material for stem cell transplantation.</P>