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Photocatalytic water splitting using hygroscopic MgO modified TiO2/WO3 dual-layer photocatalysts
Chao-Wei Huang,Chi-Hung Liao,Jeffrey Chi-Sheng Wu 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.8
MgO modified TiO2/WO3 dual-layer photocatalysts (DLP) was synthesized by radio-frequency magnetron sputtering (RFMS). The influences of MgO on the properties and the performance of the prepared DLP were investigated. MgO modified TiO2 thin films were characterized by instrumental analysis such as XRD, AFM, SEM-EDS, and UV-visible absorption spectrometry. Their photoactivity was assessed by conducting photovoltammetry followed by splitting water in a twin-cell reactor, where hydrogen gas and oxygen gas were produced separately. The yield of H2 and O2 in the twin-cell reactor corresponded to the photovoltammetry results, indicating that MgO can significantly improve the photoactivity of DLP. The improvement is attributed primarily to the hygroscopic Nature of MgO, which can increase the amount of H2O molecules on the surface of TiO2 for carrying out the photoreaction. In addition, the incorporated MgO layer can also act as an insulator to suppress the electron leakage that occurred at the TiO2-water interface.
Phase II trial of VEGFR2 inhibitor apatinib for metastatic sarcoma: focus on efficacy and safety
Zhichao Liao,Feng Li,Chao Zhang,Lei Zhu,Yehui Shi,Gang Zhao,Xu Bai,Shafat Hassan,Xinyue Liu,Ting Li,Peipei Xing,Jun Zhao,Jin Zhang,Ruwei Xing,Sheng Teng,Yun Yang,Kexin Chen,Jilong Yang 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
Apatinib (YN968D1) is a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR- 2). We conducted a single-arm, nonrandomized phase II study (NCT03121846) to assess the efficacy and safety of apatinib in patients with stage IV sarcoma. We recruited 64 patients with stage IV sarcoma who had failed chemotherapy. The primary endpoint was progression-free survival (PFS), and the secondary endpoints were progression-free survival rate (PFR), objective response rate (ORR), and disease control rate (DCR) at week 12. Treatment-related adverse effects (AEs) were evaluated. Fifty-nine patients were assessed for efficacy and 64 patients for AEs. The median PFS was 7.93 months. At 12 weeks, the PFR was 74%, the ORR was 16.95% (10/59), and the DCR was 86.44% (51/59). The final ORR was 15.25% (9/59) and the DCR was 57.63% (34/59). Notably, 22 patients (34.38%) who developed hypertension, hand-foot-skin reaction, or proteinuria had significantly longer OS than those without these AEs (18.20 vs. 10.73 months; P = 0.002). We conclude that apatinib is effective and well tolerated in patients with advanced sarcoma. The development of hypertension, hand-foot-skin reaction, or proteinuria may indicate a favorable prognosis, representing a novel finding in sarcoma patients.
Fangqing Yang,Chao Wang,Quanmi Liao,Sheng Huang 대한조선학회 2016 International Journal of Naval Architecture and Oc Vol.8 No.6
The flight deck of an aircraft carrier is relatively vulnerable compared to its hull, as the damage of some subsystems on the flight deck may cause the carrier losing its operational capability. Therefore, this work aims to represent a simulative method for evaluating the resistance of the flight deck's operational capability in the condition that the aircraft carrier is together with its strike group and the enemy uses the anti-ship missiles with the cluster warheads to attack. In the simulations, the susceptibility of the carrier and the vulnerability of the aircraft guarantee resources are gained. Then, with the help of the closed queuing network, the residual sortie generation rate can be solved, which reflects the flight deck's residual operational capability. The results have proven that the flight deck is of strong resistance to these attacks while it is very sensitive to the loss of some key aircraft guarantee resources.
Yang, Fangqing,Wang, Chao,Liao, Quanmi,Huang, Sheng The Society of Naval Architects of Korea 2016 International Journal of Naval Architecture and Oc Vol.8 No.6
The flight deck of an aircraft carrier is relatively vulnerable compared to its hull, as the damage of some subsystems on the flight deck may cause the carrier losing its operational capability. Therefore, this work aims to represent a simulative method for evaluating the resistance of the flight deck's operational capability in the condition that the aircraft carrier is together with its strike group and the enemy uses the anti-ship missiles with the cluster warheads to attack. In the simulations, the susceptibility of the carrier and the vulnerability of the aircraft guarantee resources are gained. Then, with the help of the closed queuing network, the residual sortie generation rate can be solved, which reflects the flight deck's residual operational capability. The results have proven that the flight deck is of strong resistance to these attacks while it is very sensitive to the loss of some key aircraft guarantee resources.
Jian-Shian Lin,Ming-Hua Chung,Chen-Ming Chen,Fuh-Shyang Juang,Yu-Sheng Tsai,Shu-Wei Chang,Shun-Hsi Wang,Teh-Chao Liao,Lung-Chang Liu 한국물리학회 2010 Current Applied Physics Vol.10 No.5
UV-curable organic/inorganic hybrid composites with gas barrier and heat-dissipating capability have been successfully fast synthesized with microwave irradiation and utilized for the encapsulation of top-emitting organic light-emitting diodes (TEOLEDs). Experimental results manifest that lab-made organic/inorganic hybrid composites can effectively not only obstruct the invasion of moisture as well as oxygen in the atmosphere into the device but also lower the temperature of device. Therefore, the lifetimes of TEOLEDs with their encapsulation are 2.2 folds longer than those without encapsulation.