A Micro Oven-Control System for Inertial Sensors

Donguk Yang,Jong-Kwan Woo,Sangwoo Lee,Mitchell, Jay,Challoner, Anthony Dorian,Najafi, Khalil Institute of Electrical and Electronics Engineers 2017 Journal of microelectromechanical systems Vol.26 No.3

<P>This paper presents a modular and generic micromachined oven-control system for use with miniature micro-electro-mechanical system (MEMS) transducers. The micro-oven-controlled off-the-shelf commercial six-axis MEMS inertial measurement unit (IMU), Invensense MPU-6050, provides the lowest reported temperature-induced root of sum of squares bias errors of 62.71°/h and 1.920 mg from -40°C to 85°C for three-axis gyroscopes and three-axis accelerometers, respectively. The micro-oven control system provides thermal isolation from the surrounding environment using a micro-machined isolation platform, vacuum-sealing, and a metal package. In addition, a CMOS temperature sensor, a proportional-integral-derivative-based temperature control scheme, and least mean square and random forest compensation algorithms are utilized to reduce temperature-induced bias drifts of IMUs. The most stable axes achieve peak-to-peak bias drifts of 12.78°/h and 665.2 ug during a thermal-cycle test for gyroscopes and accelerometers, respectively. The oven's heater power consumption is <;125mW at the lowest temperature, -40°C. This oven-control system can be applied to a wide range of MEMS sensors to reduce performance degradation due to temperature variation.</P>

Fluorescence Response Profiling for Small Molecule Sensors Utilizing the Green Fluorescent Protein Chromophore and Its Derivatives

Lee, Jun-Seok,Baldridge, Anthony,Feng, Suihan,SiQiang, Yang,Kim, Yun Kyung,Tolbert, Laren M.,Chang, Young-Tae American Chemical Society 2011 ACS combinatorial science Vol.13 No.1

<P>Using a fluorescence response profile, a systematic examination was performed for synthetic chromophores of the green fluorescent protein (GFP) to discover new small molecule sensors. A group of 41 benzylideneimidazolinone compounds (<B>BDI</B>) was prepared and screened toward 94 biologically relevant analytes to generate fluorescence response profiles. From the response pattern, compounds containing aminobenzyl and heteroaromatic cyclic substructures revealed a pH dependent emission decrease effect, and unlike other fluorescence scaffolds, most <B>BDIs</B> showed fluorescence quenching when mixed with proteins. On the basis of the primary response profile, we obtained three selective fluorescence turn-on sensors for pH, human serum albumin (HSA), and total ribonucleic acid (RNA). Following analysis, a fluorescence response profile testing four nucleic acids revealed the alkyloxy (Ph−OR) functional group in the <I>para</I> position of benzyl analogues contributes to RNA selectivity. Among the primary hit compounds, <B>BDI 2</B> showed outstanding selectivity toward total RNA with 5-fold emission enhancement. Finally, <B>BDI 24</B> showed selective fluorescence increase to HSA (<I>K</I><SUB>d</SUB> = 3.57 μM) with a blue-shifted emission max wavelength (Δλ<SUB>em</SUB> = 15 nm). These examples of fluorescence sensor discovery by large-scale fluorescence response profiling demonstrate the general applicability of this approach and the usefulness of the response profiles.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/acsccc/2011/acsccc.2011.13.issue-1/co100012k/production/images/medium/co-2010-00012k_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/co100012k'>ACS Electronic Supporting Info</A></P>

An OSSE Study for Deep Argo Array using the GFDL Ensemble Coupled Data Assimilation System

장유순,Shaoqing Zhang,Anthony Rosati,Gabriel A. Vecchi,Xiaosong Yang 한국해양과학기술원 2018 Ocean science journal Vol.53 No.2

An observing system simulation experiment (OSSE) using an ensemble coupled data assimilation system was designed to investigate the impact of deep ocean Argo profile assimilation in a biased numerical climate system. Based on the modern Argo observational array and an artificial extension to full depth, “observations” drawn from one coupled general circulation model (CM2.0) were assimilated into another model (CM2.1). Our results showed that coupled data assimilation with simultaneous atmospheric and oceanic constraints plays a significant role in preventing deep ocean drift. However, the extension of the Argo array to full depth did not significantly improve the quality of the oceanic climate estimation within the bias magnitude in the twin experiment. Even in the “identical” twin experiment for the deep Argo array from the same model (CM2.1) with the assimilation model, no significant changes were shown in the deep ocean, such as in the Atlantic meridional overturning circulation and the Antarctic bottom water cell. The small ensemble spread and corresponding weak constraints by the deep Argo profiles with medium spatial and temporal resolution may explain why the deep Argo profiles did not improve the deep ocean features in the assimilation system. Additional studies using different assimilation methods with improved spatial and temporal resolution of the deep Argo array are necessary in order to more thoroughly understand the impact of the deep Argo array on the assimilation system.

Physicochemically Stable Polymer‐Coupled Oxide Dielectrics for Multipurpose Organic Electronic Applications

Kim, Se Hyun,Jang, Mi,Yang, Hoichang,Anthony, John E.,Park, Chan Eon WILEY‐VCH Verlag 2011 Advanced Functional Materials Vol.21 No.12

<P><B>Abstract</B></P><P>A chemically coupled polymer layer is introduced onto inorganic oxide dielectrics from a dilute chlorosilane‐terminated polystyrene (PS) solution. As a result of this surface modification, hydrophilic‐oxide dielectrics gain hydrophobic, physicochemically stable properties. On such PS‐coupled SiO<SUB>2</SUB> or AlO<SUB><I>x</I></SUB> dielectrics, various vacuum‐ and solution‐processable organic semiconductors can develop highly ordered crystalline structures that provide higher field‐effect mobilities (<I>μ</I><SUB>FET</SUB>s) than other surface‐modified systems, and negligible hysteresis in organic field‐effect transistors (OFETs). In particular, the use of PS‐coupled AlO<SUB><I>x</I></SUB> nanodielectrics enables a solution‐processable triethylsilylethynyl anthradithiophene OFET to operate with <I>μ</I><SUB>FET</SUB> ∼ 1.26 cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP> at a gate voltage below –1 V. In addition, a complementary metal‐oxide semiconductor‐like organic inverter with a high voltage gain of approximately 32 was successfully fabricated on a PS‐coupled SiO<SUB>2</SUB> dielectric.</P>

Implementation of LoRa-based Water-saving Irrigation System

Jeongjun Lee,Subeen Jeong,Myungwoo Yang,Connor Polanka,Anthony H Smith,Minsun Lee 한국통신학회 2020 한국통신학회 학술대회논문집 Vol.2020 No.8

Bisphosphonate Use Does Not Impact Survival in Patients with Pancreatic Cancer: A Propensity Score Matching Analysis

( Haley M. Zylberberg ),( Sheila D. Rustgi ),( Anthony Yang ),( Anne Aronson ),( Elizabeth Kessel ),( Sunil Amin ),( Aimee L. Lucas ) 대한간학회 2021 Gut and Liver Vol.15 No.5

Background/Aims: Bisphosphonates are increasingly recognized for their anti-neoplastic properties, which are the result of their action on the mevalonate pathway. Our primary aim was to investigate the association between bisphosphonate use and survival in patients with pancreatic cancer. Since statins also act on the mevalonate pathway, we also investigated the effect of the combined use of bisphosphonates and statins on survival. Methods: The Surveillance, Epidemiology, and End Results registry (SEER)-Medicare linked database was used to identify patients with pancreatic ductal adenocarcinoma (PDAC) between 2007 and 2015. Kaplan-Meier models were used to examine the association between survival with bisphosphonate use alone and in combination with statins within 1 year prior to the diagnosis of PDAC. Propensity score matching analysis and Cox-proportional hazard models were used to determine the association between overall survival with bisphosphonate use alone and combined with statins, after adjusting for relevant confounders, such as the Charlson comorbidity index score, stage, treatment, sociodemographic characteristics, and propensity score. Results: In total, 13,639 patients with PDAC were identified, and 1,203 (8.82%) used bisphosphonates. There was no difference in the mean survival duration between bisphosphonate users (7.27 months) and nonusers (7.25 months, p=0.61). After adjustment for confounders, bisphosphonate use was still not associated with improved survival (hazard ratio, 1.00; 95% confidence interval, 0.93 to 1.08; p=0.96). Combined bisphosphonate and statin use was also not associated with improved survival (hazard ratio, 0.97; 95% confidence interval, 0.87 to 1.07; p=0.48) after adjustment for confounders. Conclusions: Our findings suggest that the use of bisphosphonates, whether alone or in combination with statins, does not confer a survival advantage in patients with PDAC. (Gut Liver 2021;15:782-790)

An OSSE Study for Deep Argo Array using the GFDL Ensemble Coupled Data Assimilation System

Chang, You-Soon,Zhang, Shaoqing,Rosati, Anthony,Vecchi, Gabriel A.,Yang, Xiaosong Korean Ocean Research & Development Institute and 2018 OCEAN SCIENCE JOURNAL Vol.53 No.2

An observing system simulation experiment (OSSE) using an ensemble coupled data assimilation system was designed to investigate the impact of deep ocean Argo profile assimilation in a biased numerical climate system. Based on the modern Argo observational array and an artificial extension to full depth, 'observations' drawn from one coupled general circulation model (CM2.0) were assimilated into another model (CM2.1). Our results showed that coupled data assimilation with simultaneous atmospheric and oceanic constraints plays a significant role in preventing deep ocean drift. However, the extension of the Argo array to full depth did not significantly improve the quality of the oceanic climate estimation within the bias magnitude in the twin experiment. Even in the 'identical' twin experiment for the deep Argo array from the same model (CM2.1) with the assimilation model, no significant changes were shown in the deep ocean, such as in the Atlantic meridional overturning circulation and the Antarctic bottom water cell. The small ensemble spread and corresponding weak constraints by the deep Argo profiles with medium spatial and temporal resolution may explain why the deep Argo profiles did not improve the deep ocean features in the assimilation system. Additional studies using different assimilation methods with improved spatial and temporal resolution of the deep Argo array are necessary in order to more thoroughly understand the impact of the deep Argo array on the assimilation system.

Photo‐Curable Polymer Blend Dielectrics for Advancing Organic Field‐Effect Transistor Applications

Kim, Se Hyun,Hong, Kipyo,Jang, Mi,Jang, Jaeyoung,Anthony, John E.,Yang, Hoichang,Park, Chan Eon WILEY‐VCH Verlag 2010 Advanced Materials Vol.22 No.43

<P><B>A solution method of photo‐curable and ‐patternable polymer gate dielectrics</B> was introduced by using blend solutions of poly(4‐dimethylsilyl styrene) (PDMSS) and poly(melamine‐co‐formaldehyde) acrylate (PMFA). The fabrication was optimized to produce a smooth hydrophobic gate dielectric with good insulating and solvent‐resistant properties. On the optimized PDMSS/PMFA blend gate dielectric, pentacene could grow into highly ordered structure, showing high electric performances for the resulting OFETs, as well as PTCDI‐C13 and TES‐ADT.</P>

Unified film patterning and annealing of an organic semiconductor with micro-grooved wet stamps

Kim, K.,Jang, M.,Lee, M.,An, T.,Anthony, J.,Kim, S.,Yang, H.,Park, C. Royal Society of Chemistry 2016 Journal of Materials Chemistry C Vol.4 No.29

<P>A unified patterning and annealing approach was successfully demonstrated for 5,11-bis(triethylsilylethynyl)-anthradithiophene (TES-ADT) films spun-cast on polymer-treated SiO2 dielectrics. First, rubbery polydimethylsiloxane (mu-PDMS) stamps with microscale periodic grooves were swollen in 1,2-dichloroethane and then softly placed onto amorphous-like TES-ADT films. In this case, the film sides physically in contact with the wet stamps were quickly absorbed into the PDMS matrix while the non-contact area formed highly ordered phases by the solvent-annealing effect. The resulting patterns of TES-ADT contained discernable crystallites, where the grain sizes drastically decreased and their shapes transformed from spherulites to optically featureless ones with a decreasing line width from 100 to 2.5 mu m. Unlike ordinary systems containing spherulitic domains, the 2.5 mu m line-confined TES-ADT patterns contained layer-stacked crystallites but an optically invisible grain boundary, yielding an unexpectedly high field-effect mobility of 2.60 cm(2) V-1 s(-1) in organic field-effect transistors (OFETs), with narrow deviations less than 8% (averaged from 42 devices). The results suggest that the well pi-overlapped grains and their smooth connections are key factors to achieve high performance multi-array OFET applications.</P>

Soft, thin skin-mounted power management systems and their use in wireless thermography

Lee, Jung Woo,Xu, Renxiao,Lee, Seungmin,Jang, Kyung-In,Yang, Yichen,Banks, Anthony,Yu, Ki Jun,Kim, Jeonghyun,Xu, Sheng,Ma, Siyi,Jang, Sung Woo,Won, Phillip,Li, Yuhang,Kim, Bong Hoon,Choe, Jo Young,Huh National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.22

<P>Power supply represents a critical challenge in the development of body-integrated electronic technologies. Although recent research establishes an impressive variety of options in energy storage (batteries and supercapacitors) and generation (triboelectric, piezoelectric, thermoelectric, and photovoltaic devices), the modest electrical performance and/or the absence of soft, biocompatible mechanical properties limit their practical use. The results presented here form the basis of soft, skin-compatible means for efficient photovoltaic generation and high-capacity storage of electrical power using dual-junction, compound semiconductor solar cells and chip-scale, rechargeable lithium-ion batteries, respectively. Miniaturized components, deformable interconnects, optimized array layouts, and dual-composition elastomer substrates, superstrates, and encapsulation layers represent key features. Systematic studies of the materials and mechanics identify optimized designs, including unusual configurations that exploit a folded, multilayer construct to improve the functional density without adversely affecting the soft, stretchable characteristics. System-level examples exploit such technologies in fully wireless sensors for precision skin thermography, with capabilities in continuous data logging and local processing, validated through demonstrations on volunteer subjects in various realistic scenarios.</P>