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Zhi Tong,Miaoyu Li,Dachuan Lib,Kui Wu,Xiaoyu Yang 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.2
Porous mullite ceramic membrane supports were prepared by fly ash as the main raw material, with addition of loess andbauxite in the ratio of silicon to aluminium in the mullite phase (3Al2O3-2SiO2), calcium carbonate as pore-forming agents andpolyvinyl alcohol as the binder. The effects of calcium carbonate addition (0, 5, 10, and 15 wt%) and sintering temperatureon the performance of prepared supports, including crystalline phase evolution, microstructure, porosity, flexural strength,and pure water flux, were investigated. The results shows that the increase in sintering temperature is beneficial to theformation of the mullite crystalline phase and improves flexural strength. When the sintering temperature reached 1200 °Cand the calcium carbonate content was 5%, the porosity of the support was 46.3% and the flexural strength was 77.7 MPa. Based on the experiments, central composite experiments and response surface analysis were carried out to optimise thepreparation conditions, and determine the optimum amount of calcium carbonate addition and sintering temperature. Theresults of the study are of reference value for the study of inorganic ceramic membrane support.
Clearance Measurement Equipment for Gas Lubricated Dynamic Pressure Bearing of Gyro Motor
Tong-qun Ren,Zhi-rou Liu,Xiang-dong Xu,Yu Liu,Xiaodong Wang 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.12
The clearance of gas lubricated dynamic pressure bearing of gyro motor refers specifically to small internal air gap between the rotor and stator. The clearance size is an important indicator of running performance of a motor. In this work, a dedicated clearance measurement equipment is developed. The clearance is converted to external micro displacement and measured by dual inductive probes with relative measurement principle. For this purpose, three main functional modules are designed together with corresponding electronic and pneumatic control systems. The clamp fixation module helps to support the measured bearing flexibly at the shaft end, which is conducive to protect the bearing and ensure the smoothness of force application. The force application module consists of a 3-D precision motion platform and a triaxial force sensor. It converts internal air gap to external micro displacement in cooperation with the clamp fixation module. The displacement measurement module is a 2-D precision motion platform carrying dual inductive probes. Based on theoretical analysis and practical experiments, the measurement accuracy is superior to 0.3 μm. Moreover, it realizes controllable and continuous force application, which is suitable for batch measurement.
Effects of Chronic Mild Stress in Female Bax Inhibitor-1-Gene Knockout Mice
Zhi-Yan Sui,Han Jung Chae,Guang-Biao Huang,Tong Zhao,Sushma Shrestha Muna,정영철 대한정신약물학회 2012 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.10 No.3
Objective: The anti-apoptotic protein Bax inhibitor-1 (BI-1) is a regulator of apoptosis linked to endoplasmic reticulum (ER)stress, and BI-1-/- mice exhibit increased sensitivity to tissue damage. The purpose of this study was to investigate the role of BI-1 in the pathogenesis of chronic mild stress (CMS)-induced depression-like behaviors in BI-1-/- mice. Methods: We delivered CMS for 2 or 6 weeks in BI-1-knockout and wild-type mice. Control groups of BI-1-knockout and wild-type mice were left undisturbed. The measured parameters were sucrose consumption at weeks 1, 2, 3, 4, 5, and 6, spontaneous locomotion, and a forced swimming test (FST) at weeks 2 and 6. Results: Significant decreases in sucrose consumption and increases in immobility time in the FST were observed in both stress groups compared with the non-stress groups. Interestingly, at week 2, but not at week 6, BI-1-/--stress mice showed less sucrose intake and greater immobility time than did BI-1+/+-stress mice. Conclusion: These results suggest that BI-1 may play role in protecting against the depressogenic effects of CMS in the short term, but not in the long term. Further study is required to deepen understanding of the role of BI-1 in protecting against depression.
Design of Coordination-Crosslinked Nitrile Rubber with Self-Healing and Reprocessing Ability
Zhi Fei Zhang,Xue Tong Liu,Kun Yang,Shu Gao Zhao 한국고분자학회 2019 Macromolecular Research Vol.27 No.8
In this work, we describe a simple approach to design of a coordination crosslinked elastomer with extraordinary mechanical properties: self-healing and recycling abilities by introducing Co-cyano coordination into nitrile rubber(NBR) matrix. The formation of reversible coordination crosslink network results in good mechanical properties superior to conventional sulfur-cured NBR, such as high stretchability and toughness. The reversibility of metal-ligand bond endows the polymer with self-healing capability and recycling or reprocessing abilities by rearrangement at elevated temperature. The fully cut samples after self-healing or reprocessing can restore their original tensile strength. It is also worth noting that the reclaimed NBR exhibited higher modulus than its original sample due to the compensation of new metal-ligand bonds formed during heating. This study provides possibilities to extend lifetime, reshaping and recycling capabilities of commercial rubber and reduce toxicity and environmental issues caused by waste rubber.
Zhi Wang,Longxiang Wu,Shiyu Tong,Xiheng Hu,Xiongbing Zu,Yuan Li,Wei He,Longfei Liu,Minfeng Chen,Lin Qi 한국통합생물학회 2016 Animal cells and systems Vol.20 No.2
Resveratrol possesses a wide spectrum of pharmacological properties and has been an ideal alternative drug for the treatment of different cancers, including prostate cancer. However, the mechanisms by which resveratrol inhibits the growth of prostate cancer are still not fully elucidated. To understand the effect of resveratrol on the apoptosis and the epithelial-tomesenchymal transition (EMT) of prostate cancer as well as its related mechanism, we investigated the potential use of resveratrol in PC-3 prostate cancer cells in vitro using real-time PCR, fluorescence-activated cell sorting, Western blotting, etc. Resveratrol suppresses the PC-3 prostate cancer cell growth and induces apoptosis. Resveratrol also influences the expression of EMT-related proteins (increased E-cadherin and decreased Vimentin expression). Finally, resveratrol also suppressed Akt phosphorylation in PC-3 cells. This study indicates that resveratrol may be a potential anti-cancer treatment for prostate cancer; moreover, it provides new evidence that resveratrol suppresses prostate cancer growth and metastasis.
( Xiu Zhi Gao ),( Hui Liu ),( Xin Xin Yi ),( Yi Qian Liu ),( Xiao Dong Wang ),( Wen Sheng Xu ),( Qi Gen Tong ),( Zong Jun Cui ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.12
Traditional soybean paste from Shandong Liangshan and Tianyuan Jiangyuan commercial soybean paste were chosen for analysis and comparison of their bacterial and fungal dynamics using denaturing gel gradient electrophoresis and 16S rRNA gene clone libraries. The bacterial diversity results showed that more than 20 types of bacteria were present in traditional Shandong soybean paste during its fermentation process, whereas only six types of bacteria were present in the commercial soybean paste. The predominant bacteria in the Shandong soybean paste were most closely related to Leuconostoc spp., an uncultured bacterium, Lactococcus lactis, Bacillus licheniformis, Bacillus spp., and Citrobacter freundii. The predominant bacteria in the Tianyuan Jiangyuan soybean paste were most closely related to an uncultured bacterium, Bacillus licheniformis, and an uncultured Leuconostoc spp. The fungal diversity results showed that 10 types of fungi were present in the Shandong soybean paste during the fermentation process, with the predominant fungi being most closely related to Geotrichum spp., an uncultured fungal clone, Aspergillus oryzae, and yeast species. The predominant fungus in the commercial soybean paste was Aspergillus oryzae.
Grain Boundary-Mediated Reduction of Radiation Defects in Different W-Based Alloys
Xiao‑Tong Li,Xiao‑Zhi Tang,Ya‑Fang Guo 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.9
Grain boundaries (GBs) are believed as potent defect sinks that contribute to the radiation damage reduction of materials. The defect-GB interaction has been extensively studied in pure metals, but only a few works shed light on the influence ofmaterial component such as alloying elements. In this study, the GB-mediated reduction of radiation defects in four W-basedalloys (W–Re, W–Ta, W–Mo and W–V) is systematically investigated by atomistic simulations. Quantitative results showthat the defect reduction in W-based alloys is significantly decreased comparing with elementary W. The principal reasonfor this decrease is the presence of various micro configurations where the solute-defect binding interactions are strong. Solutes with high local stress for each atom have a positive effect on the absorption of interstitials by GB. The ability ofGB to absorb interstitials is enhanced with the increasing temperature, and also the accumulation of vacancies is increasedwhen the temperature is as high as 1200 K. The findings in this work provide useful information on the design of radiationtolerance materials.