위절제술 후 발생한 유미성 복수 -증례 보고-

윤효영, 송영진, 류동희, 김대훈 충북대학교 의과대학 충북대학교 의학연구소 2011 忠北醫大學術誌 Vol.21 No.2

-본문참고-

Carbamazepine이 만성 정신분열증 환자의 혈액, 간 기능에 미치는 영향

강대엽,김철응,김융희,한광수 용인정신의학연구소 1994 용인정신의학보 Vol.1 No.2

Hydroxypropyl cellulose를 이용하여 제조한 cholestric gel의 액정특성 및 팽윤거동

마영대,김경희 단국대학교 1999 산업기술연구 Vol.1 No.-

The hydroxypropyl cellulose(HPC) with decree of substiturion DS ?? 2.7 and molar substitution MS = 4.9 was prepared by reaction of alkali cellulose with propylene oxide in an autoclave(10bar) at 70℃ for 16hr, and the HPC solid films crossliked with glyoxal, retaining cholestric liquid crystalline order, were prepared by casting the liquid crystalline solution in water. The liquid-crystalline properties of HPC itself and the crosslinked films and the anisotropic swelling behaviour of the corsslinked films in water were investigated. The HPC displays reflection colors in the temperature range about 30-150℃. The circular dicroism(CD) spectra of HPC show negative CD with the wavelength at the peak increasing with temperature, suggesting that the HPC has a right-handed helicoidal structure whose pitch increase with temperature. The crosslinked films display fingerprint patterns in the temperature range about 30-180℃, showing that the pitch of crosslinked films is longer than that of HPC itself. The pitch of crosslinked films increases with increasing temperature and concentration of crosslinking agent. The weight and volume swelling ratios for crosslinked films decrease with increasing of crosslinker concentration. The crosslinked films did not show preferred direction of swelling, suggesting that the three-dimensional crosslinking preferentially performs between HPC molecules under our experimental condition. The density of the crosslinked films increases with increasing crosslinking agent concentration.

Hydroxypropyl cellulose의 acrylic acid 에스테르와 allyl 에테르를 이용하여 제조한 cholesteric겔의 열 및 팽윤특성

마영대,김경희 단국대학교 2000 論文集 Vol.35 No.-

The acrylic acid esters(ES-N) and allyl ethers(ET-N) of hydroxypropyl cellulose(HPC), which are heat- and light-sensitive polymers, were prepared from HPC and acryloyl chloride and allyl chloride, respectively. The cross-linked ES-N and ET-N films, retaining cholesteric liquid crystalline order, were also prepared by photo-cross- linking thermotropic mesophases of ES-N and ET-N, respectively. Both thermal properties of the uncross-linked and cross-linked films and the swelling behavior of the cross-linked films in both acetone and water were investigated. All uncross-linked films showed isotropization temperatures(T_is) that increase with increasing the degree of substitution(DS), showing that the Ti of ES-N is slightly higher than that of ET-N at the same DS. However, all cross-linked films did not show an isotropic phase and their birefringent textures of a polygonal focal conic organization, which are similar to those in the uncross-linked firms, were maintained up to about 230℃ corresponding to the degradation temperature. The weight and volume swelling ratios in both solvents for all cross-linked films decreased with increasing DS, depending on the solvent and cross-linking species. All cross-linked films exhibited an anisotropic swelling in acetone, but hardly in water.

Methyl Methacylate/Vinyl Acetate/Toluene 라디칼공중합계에 대한 속도론적 연구

마영대,원유찬 단국대학교 1997 論文集 Vol.31 No.-

The free-radical copolymerization of methy methacrylate and vinyl acetate at 40℃ in toluene was examined by the steady-state polymerization. The following results were obtained: The copolyemr composition confirms the terminal model. The reactivity ratios of this system agree with those of the bulk system within the experiment error, which means that the solvent had very little effect on the copolymer composition of this system. Velocity-of-copolymerization data were interpreted on the basis of the current notions that the penultimate unit effect with respect to absolute values of propagation rate constant (but not with respect to the monomer reactivity ratios) is a general rule and the termination step is well represented by the penultimate model with the geometric mean approximaton. By using these models, a new equation was derivied, which was found to describe experimental data well.

퉁퉁마디로부터 염에 의하여 유도되는 Aldolase 유전자의 분리 및 발현분석

차준영,네티 엘마와티,김순길,이증주,임채오,정우식,이곤호,손대영 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Soil salinity is one of the most serious abiotic stresses limiting the productivity of agricultural crops. To cope with salt stress, plants respond with physiological, developmental and biochemical changes, including the synthesis of a number of proteins and the induction of gene expression. Salicornia herbacea is a halophytic plant that grows in salt marches and on muddy seashores. In order to understand the biochemical and molecular mechanisms of salt tolerance in S. herbacea, we isolated several genes that involved in the salt tolerance by mRNA differential display.Here we report the cloning of a cDNA encoding fructose-1, 6-bisphosphate aldolase, named ShADL, which is 1293 bp long and contains an open reading frame consisted of 359 amino acids with calculated molecular mass of 39 kDa. ShADL protein showed 86% identity with Arabidopsis and 78% with aldolase of common ice plant. Northern blot analysis revealed that the transcript of ShADL gene was increased dramatically depending on the NaCI concentrations.

폴리메틸렌 스페이서로 연결된 Cholesterol-twins의 합성과 이들의 열방성 액정의 특성

마영대,정승용,최정훈 단국대학교 2001 산업기술연구 Vol.2 No.-

Cholesterol-twins connected with central methylene chains (Cho-TW-n, where n, the number of methylene group, is 2, 4, 6, or 8) were prepared, and their thermal and mesomorphic properties were investigated. Among the samples, only Cho-TW-4 exhibited an enantiotropic cholesteric phase and the remainder a monotropic one. The monotropic isotropic-cholesteric and crystallization temperatures of the derivatives decreased irregularly with increasing n up to 6, after which they were virtually constant. All samples, which exhibit reflection colors over the full cholesteric range, formed left-handed helicoidal structures whose optical pitches (λ_ms) decrease with increasing temperature. It was also found that the temperature dependence of λ_m was virtually identical for all compounds. However, the magnitude of λ_m at the same temperature was sensitive to n.

공침법에 의한 BiDy₂Fe_(5)O_(12) 결정형 나노입자 분말의 제조 및 응용 연구

홍영대,조정환,김태엽,전성욱,홍영명 고신대학교 자연과학연구소 2007 고신대학교 자연과학연구소 논문집 Vol.14 No.-

금속산화물들은 각종 산업재료로서 유용하며 더욱이 그것들의 결정형 나노입자를 경제적으로 제조하는 기술은 21세기 첨단산업에 매우 중요하다. 저자들은 前報에서 화학합성법에 의한 각종 금속산화물의 나노입자를 제조하는 표준공정법을 연구하여 보고하였다. 본 연구에서는 그 표준공정법을 이용하여, 가넷의 일종인 BiDy_(2)Fe_(5)O_(12) 결정 나노입자 분말을 제조하고 그것의 자성체로의 응용을 위해 제품특성을 조사하었다. 가네트 제조과정에 필요한 침전물은 제품설계에 의거 몰비로 계산된 Bi, Dy, Fe의 질산염들의 혼합수용액에 침전제로서 pH NH_(3)-NH_(4)CI 완충용액 일정량을 가하여 얻어졌다. 이렇게 제조된 침전은 열처리과정을 거처 BiDy_(2)Fe_(5)O_(12) 결정형 나노입자 분말로 만들어졌다. 얻어진 제품의 입자크기, 조성, 결정구조 및 광자기성 등 특성시험이 SEM, ICP, XRD, 그리고 VSM 등을 사용하여 실시되었다. 각종 분석법을 사용하여 제품의 특성을 조사한 결과, 최초에 설계한 대로의 자성체가 나노 크기의 분말로 얻어졌으며 이것을 통하여 전보에서 확립한 표준공정법의 유효성도 입증되었다. Metallic oxides are useful as various industrial materials. Futhermore, the cost-effective techniques of fabricating the crystalline nanopartides of metallic oxides are very important for the high-tech industries of the 21 century, In the previous study, the authors reported the standard process for the preparation of crystalline nanoparticles of metallic oxides by chemical synthesis, In this study, BiDyzFesOiz nanoparticles were prepared by using the reported standard process and the characteristics of the product were investigated for applicability as magnetic substance. The precipitation needed for manufacturing process of garnet was made by adding the NH_(3)-NH_(4)CI buffer solution of pH 10 to the mixed solution of bismuth (III) nitrate, dysprosium(III) nitrate and iron(III) nitrate. The amount of each nitrate was calculated by the designed mole ratios. The nano-size crystalline powders of BiDy_(2)Fe_(5)O_(12) were earned by heating the precipitation at 800℃ for 4 hours in air. The characterizations, such as particle size, composition, crystal structure and magneto-optical property of garnet were tested by SEM, ICP, XRD, and VSM analyses. The results of the analyses showed the following two facts. First, a good magnetic substance of BiDy_(2)Fe_(5)O_(12) was earned as crystalline nano-size powders according to the original design. Next, the established standard process for the fabrication of METALLIC oxides nanonartieles was approved as a very effective method.

학습장애자의 직업재활 문제와 전망

강위영,정대영 大邱大學校 再活科學硏究所 1991 再活科學硏究 Vol.9 No.1

we are taking a growing interests in special education and vocational rehabilitation for learning disabled students, but our approaches to them are not enough to meet their specific needs. In this paper, the special education and vocational rehabilitation for learning disabled students are reviewed, which implies the followings; First, the special education and vocational rehabilitation for LD students should be established legally and systematically. Second, our classifications for the handicapped should be improved to include all the handicapped, because present classification systems are much more simplfied than those of WHO's. Third, learning disabilities are lifelong probelms of individuals, therefore LD definition should be reconsidered in terms of special education and vocational rehabilitation, and educational approachs to them should be consider with their vocational rehabilitation. Fourth, being implemented through educational-industrial cooperation, special and vocational rehabilitation for LD will surmount the limitations in school environments and be able to expect more efficient results. In addition, more concrete subtypes of LD and appropriate programs for them should be studied and developed respectively. Educational systems for special teachers and rehabilitation specialists in this field should be prepared in college level.

Phenobarbital 前處置量이 Dimethylnitrosamine의 白鼠肝의 中毒性 病變에 미치는 影響에 關한 硏究

姜大榮 충남대학교 의과대학 지역사회의학연구소 1979 충남의대잡지 Vol.6 No.2

Dimethylnitrosamine, potent hepatotoxic and carcinogenic agent, is metabolized mainly in the liver, and its hepatotoxic action is influenced by the administration of phenobarbital which is thought as inducer of hepatic drug-metabolizing enzyme. In order to study the effects of phenobarbital pretreated dosage on the hepatotoxic changes of dimethylnitrosamine, phenobarbital were administered with 100mg every consecutive day to the male albino rats intraperitoneally, and then 60mg, 50mg, 40mg, and 30mg/kg of dimethylnitrosamine in physiologic saline solution were given by intraperitoneal injection. The mortality and histopathologic changes between control (dimethylnitrosamine only) and experimental groups were as follows: 1. Mortality in 60mg, 50mg, 40mg and 30mg injected rats indicated 80%, 50%, 40% and 15%, whereas phenobarbital 3 successive days' pretreated rats in corresponding group sustained 25%, 20%, 15%, and 5% of death rate, respectively, 6 successive days' pretreated rats 30%, 20%, 20% and 10%, 9 successive days' pretreated rats 75%, 70% and 17%. 2. The rats given 60mg, and 50mg of DMN, cause acute massive hemorrhage in the liver, and then the necrotic changes were more extensive and intensive in the early experimental days, and progressed with lessened thereafter. The phenobarbital 300mg pretreated groups were less intensive in their lesions and fastened their recovery than DMN-injected groups. The hemorrhagic necrotic changes in phenobarbital 600mg and 900mg phenobarbital groups, were less intensive on the first day of experiment, compared with 300mg pretreated groups, but after that more intensive and prolonged. 3. Necrotic changes in the 40mg and 30mg of DMN injected groups developed mild to moderate degree in the first experimental day, and became worse in successive 1-2 days, whereas in phenobarbital 300mg pretreated groups the lesions were more mild and shortened their course than those in DMN injected groups, but in phenobarbital 600mg and 900mg pretreated groups, necrotic changes were mild on the first day of experiment, but after that became more intensive and prolonged. 4. Hepatic fibrosis in both DMN-injected and phenobarbital pretreated groups developed around the date when necrotic changes were subsided, but in phenobarbital pretreated groups were less intensive and shorter course than each corresponding DMN-injected group. There are no specific relationships between necrotic or fibrotic change and phenobarbital pretreated dosage.