Effect of Korean Red Ginseng on Psychological Functions Patients with Severe Climacteric Syndromes : A Comprehensive Study from the Viewpoint of Traditional KAMPO-medicine and Western Medicine

Tode, Takehiko,Kikuchi, Yoshihiro The Korean Society of Ginseng 2003 Journal of Ginseng Research Vol.27 No.3

Objective; Antistress effect of Korean red ginseng (RG) on postmenopausal women with severe climacteric syndrome (CS) were evaluated from the viewpoint of traditional KAMPO-medicine and Western medicine. Methods; All patients with CS were treated with daily oral administration of 6g RG for 30 days. Nine patients with CS were evaluated with the use of diagnostic scores for KI-deficiency (deficiency of vital energy) and OKETSU (blood stagnation) syndrome from the viewpoint of KAMPO-medicine. In the same patients with CS, peripheral blood levels of ${\beta}$-endorphin and total plasminogen activator inhibitor-1 (t-PAI-1) were measured before and after treatment with RG. In another group, 12 patients with CS, psychological test using CMI, STAI and SDS were performed from the viewpoint of Western medicine. Stress related hormones, such as ACTH, cortisol and DHEA-S in those 12 patients with CS were also measured before and after treatment with RG. Results; KI-deficiency score and OKETSU score in patients with CS were significantly (p<0.001) higher than those in patients without CS. After treatment with RG, both scores were markedly (p<0.001) decreased compared to before treatment with RG. ${\beta}$-endorphin levels in patients with CS were significantly (p<0.05) higher than those in patients without CS. Total PAI-levels in patients with CS were increased before treatment with RG. No significant difference, however, were observed between patients with and without CS. After treatment with RG, both levels of ${\beta}$-endorphin and total PAI-1 in patients with CS were significantly (p<0.001 and p<0.05, respectively) decreased compared to before treatment with RG. CMI and STAI scores in patients with CS were significantly (p<0.05) higher than those in patients without CS. SDS scores in patients with CS were also markedly (p<0.00l) higher than in those without CS. After treatment with RG, all scores decreased within normal range. DHEA-S levels in patients with CS were about a half of those without CS. Consequently, cortisol/DHEA-S (C/D) ratio was significantly(p<0.001) higher in patients with CS than in those without CS. Although the decreased DHEA-S levels were not restored to the levels in patients without CS, the C/D ratio decreased significantly (p<0.05) after treatment with RG. Conclusion; Reinforcement of vital energy and improvement of stagnant blood circulations by oral administration of RG were elucidated from the viewpoint of traditional KAMPO-medicine. From the viewpoint of Western medicine, effect of RG on postmenopsusal women with CS seemed to be brought about in part by not only an improvement of psychoneuroendocrine dysfunctions but also an amelioration of blood coagulation systems.

Effect of Korean Red Ginseng on Psychological Functions in Patients with Severe Climacteric Syndromes : A Comprehensive Study from the Viewpoint of Traditional KAMPO-medicine and Western Medicine

Takehiko Tode,Yoshihiro Kikuchi 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.3

Objective; Antistress effect of Korean red ginseng (RG) on postmenopausal women with severe climacteric syndrome (CS) were evaluated from the viewpoint of traditional KAMPO-medicine and Western medicine. Methods; All patients with CS were treated with daily oral administration of 6g RG for 30 days. Nine patients with CS were evaluated with the use of diagnostic scores for KI-deficiency (deficiency of vital energy) and OKETSU (blood stagnation) syndrome from the viewpoint of KAMPO-medicine. In the same patients with CS, peripheral blood levels of β-endorphin and total plasminogen activator inhibitor-1 (t-PAI-1) were measured before and after treatment with RG. In another group, 12 patients with CS, psychological test using CMI, STAI and SDS were performed from the viewpoint of Western medicine. Stress related hormones, such as ACTH, cortisol and DHEA-S in those 12 patients with CS were also measured before and after treatment with RG. Results; KI-deficiency score and OKETSU score in patients with CS were significantly (p<0.001) higher than those in patients without CS. After treatment with RG, both scores were markedly (p<0.001)<br/> decreased compared to before treatment with RG. β-endorphin levels in patients with CS were significantly (p<0.05) higher than those in patients without CS. Total PAI-1 levels in patients with CS were increased before treatment with RG. No significant difference, however, were observed between patients with and without CS. After treatment with RG, both levels of β-endorphin and total PAI-1 in patients with CS were significantly (p<0.01 and p<0.05, respectively) decreased compared to before treatment with RG. CMI and STAI scores in patients with CS were significantly (p<0.05) higher than those in patients without CS. SDS scores in patients with CS were also markedly (p<0.001) higher than in those without<br/> CS. After treatment with RG, all scores decreased within normal range. DHEA-S levels in patients with CS were about a half of those without CS. Consequently, cortisol/DHEA-S (C/D) ratio was significantly (p<0.001) higher in patients with CS than in those without CS. Although the decreased DHEA-S levels were not restored to the levels in patients without CS, the C/D ratio decreased significantly (p<0.05) after treatment with RG. Conclusion; Reinforcement of vital energy and improvement of stagnant blood circulations by oral administration of RG were elucidated from the viewpoint of traditional KAMPO-medicine. From the viewpoint of Western medicine, effect of RG on postmenopausal women with CS<br/> seemed to be brought about in part by not only an improvement of psychoneuroendocrine dysfunctions but also an amelioration<br/> of blood coagulation systems.

A ROUTING METHOD BASED ON REQUIRED COMMUNICATION QUALITIES IN HIGH-SPEED MULTIMEDIA NETWORK

Hideki Tode,Ken Ojiri,Miki Yamamoto,Hironmi Okada,Hiromasa Ikeda 한국통신학회 1995 Asia-Pacific Conference on Communications Vol.2 No.1

Clinical Usefulness of Korean Red Ginseng in Postmenopausal Women with Severe Climacteric Disturbance

Yoshihiro Kikuchi(Yoshihiro Kikuchi),Takehiko Tode(Takehiko Tode),Junko Hirata(Junko Hirata),Hideyuki Nakata(Hideyuki Nakata),Tsunekazu Kita(Tsunekazu Kita) 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.3

The aim of this study is to evaluate clinical usefulness of Korean red ginseng (RG) on various postmenopausal syndromes. Total plasminogen inhibitor-1 (tPAI-1) in peripheral blood from 9 postmenopausal women with climacteric syndromes (CS) was measured before and 3 months after treatment with daily oral administrat i on of 6g RG and that from 8 postmenopausal women without any CS was also measured as healthy controls. Blood samples were collected in the early morning on the bed-rest. Psychological conditions of postmenopausal women with CS were measured before and 3 months after treatment with RG using simplified menopausal index (SMI). In addition, OKETSU (blood stagnation) syndrome scores and KI deficiency (generalized energy stagnation) scores proposed by Terasawa et al., were recorded before and 3months after treatment with RG in postmenopausal women with CS and in healthy postmenopausal women. OKETSU syndrome scores and tPAI-1 levels in postmenopausal patients with CS were significantly (P<0.001 and<br/> P<0.01) higher than those in healthy postmenopausal women without CS. Similarly, SMI scores and KI deficiency scores in postmenopausal patients with CS were about three-fold higher than those without any CS. When RG was administered for 3 months, KI deficiency scores and OKETSU scores as well as SMI scores declined around the levels of healthy postmenopausal women. Although tPAI-1 levels significantly (P<0.05) decreased after treatment with RG, those did not reach the levels of healthy postmenopausal women. Clinical usefulness of administration of RG to postmenopausal women with CS was confirmed from evaluation not only by modern medicine but also by traditional KAMPO medicine.

Clinical Usefulness of Korean Red Ginseng in Postmenopausal Women with Severe Climacteric Disturbance

Kikuchi, Yoshihiro,Tode, Takehiko,Hirata, Junko,Nakataand, Hideyui,Kita, Tsunekazu The Korean Society of Ginseng 2003 Journal of Ginseng Research Vol.27 No.3

The aim of this study is to evaluate clinical usefulness of Korean red ginseng (RG) on various postmenopausal syndromes. Total plasminogen inhibitor-l (tPAI-l) in peripheral blood from 9 postmenopausal women with climacteric syndromes (CS) was measured before and 3 months after treatment with daily oral administration of 6 g RG and that from 8 postmenopausal women without any CS was also measured as healthy controls. Blood samples were collected in the early morning on the bed-rest. Psychological conditions of postmenopausal women with CS were measured before and 3 months after treatment with RG using simplified menopausal index (SMI). In addition, OKETSU (blood stagnation) syndrome scores and KI deficiency (generalized energy stagnation) scores proposed by Terasawa et al., were recorded before and 3 months after treatment with RG in postmenopausal women with CS and in healthy postmenopausal women. OKETSU syndrome scores and tPAI-l levels in postmenopausal patients with CS were significantly (P<0.001 and P<0.01) higher than those in healthy postmenopausal women without CS. Similarly, SMI scores and KI deficiency scores in postmenopausal patients with CS were about three-fold higher than those without any CS. When RG was administered for 3 months, KI deficiency scores and OKETSU scores as well as SMI scores declined around the levels of healthy postmenopausal women. Although tPAI-1 levels significantly (P<0.05) decreased after treatment with RG, those did not reach the levels of healthy postmenopausal women. Clinical usefulness of administration of RG to postmenopausal women with CS was confirmed from evaluation not only by modem medicine but also by traditional KAMPO medicine.

Flow-based Service Discipline for TCP Streaming in Advanced IP Router

Naotoshi Yoshihara,Hideki Tode,Koso Murakami 한국멀티미디어학회 2009 한국멀티미디어학회 국제학술대회 Vol.2009 No.-

Video-sharing applications using TCP (called "TCP streaming") like YouTube have been increased recently. However, it is difficult for the existing IP network to guarantee QoS of TCP streaming. So far, to achieve the QoS enhancement per flow, we have proposed the class-based output buffer control mechanism in QoS-aware router. In this paper, to guarantee more sophisticated QoS for TCP streaming, we propose the mechanism which calculates transmission bandwidth and buffer volume preferentially available (called "basic volume") according to active flows' condition estimated by measuring transmitted packets per flow. Furthermore, by computer simulation, the effectiveness of our proposal is verified.

Gateway management system within the border based on traffic pattern and source address routing

Yutaka Izumi,Hideki Tode 한국멀티미디어학회 2009 한국멀티미디어학회 국제학술대회 Vol.2009 No.-

Service and application using the network have been increased in the present internet, especially like e-learning and multimedia contents distribution. Then we have to take action against various invalid accesses or attacks. However, several attacks are difficult to detect and take action, because Firewall and IDS/IPS (Intrusion Detection System / Intrusion Prevention System) inspect on each packet, not chains of packet. We are developing detecting and preventing system against the attacks based on traffic pattern. This system is able to detect the attacks by chains of packets between external and internal network. Then this system changes the route of malicious packets by source address to avoid the attacks, such as the resource-exhaustion attacks. In this paper, we suggest and describe the design and implementation of this system.

Performance Evaluation on Applicability of Q-STM method to the ATM network

Noriaki Kamiyama,Hideki Tode,Miki Yamamoto,Hiromi Okada,Hiromasa Ikeda 한국통신학회 1995 Asia-Pacific Conference on Communications Vol.2 No.1

Multi-Cell Transfer Scheme for optical ATM Networks Using Virtual Path Group

Young Bok Choi,Hideki Tode,Miki Yamamoto,Hiromi Okada,Hiromasa Ikeda 대한전자공학회 1994 JTC-CSCC : Joint Technical Conference on Circuits Vol.- No.-

Configuration Method of P2P Network System with Transfer Support Nodes

Takeru Hiraishi,Hideki Tode 한국멀티미디어학회 2009 한국멀티미디어학회 국제학술대회 Vol.2009 No.-

The content distribution services via the Internet have become popular. However these services have some problems that prevent users from getting a file efficiently and there still remains much room for improving. In this paper, we focus on representative hybrid P2P[1] network application, BitTorrent[2], and try to resolve these problems. We propose the method for placing transfer support nodes, called "SupportNode", by service providers to allow users to get contents efficiently and evaluate the method by using computer simulation.