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      • KCI등재

        Remote control system based on the internet and machine vision for tracked vehicles

        Shuai Wang,Shubing Zhang,Ruoding Ma,E. Jin,Xinhui Liu,He Tian,Ruipeng Yang 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.3

        A remote control system based on the Internet and machine vision is designed in this study for tracked vehicles. The system consists of remote monitoring, remote control, and visual navigation subsystems. The on-board computer receives control commands issued by the monitoring center and controls the speed and steering angle of the tracked vehicles. The front camera collects navigation line information, and the collected image is processed by filtering, gray processing, binarization processing, and interference elimination to obtain the center point coordinates of the navigation line. Proportional-integral-derivative (PID), fuzzy PID, and neural network control algorithms are compared based on the distance and angle deviations of the preview point to control the operation of tracked vehicles through simulation. The Internet remote control system with the fuzzy PID control algorithm is then tested on a tracked vehicle. Experimental results indicate that the trajectory of the tracked vehicle fits the navigation path well.

      • KCI등재

        InP/InGaAs/InP DHBT structures with N+ doped composite collectors grown by gas source molecular beam epitaxy

        Anhuai Xu,Likun Ai,Hao Sun,Ming Qi,Shubing Su,Xinyu Liu,Xunchun Liu,He Qian 한양대학교 세라믹연구소 2006 Journal of Ceramic Processing Research Vol.7 No.2

        InP/InGaAs/InP double heterojunction bipolar transistor (DHBT) structural materials with N+ doped composite collectors were designed and grown successfully by gas source molecular beam epitaxy (GSMBE). High-quality lattice-matched InGaAs/ InP hetero epi-layers were obtained through optimizing the growth conditions. The performance of InP/InGaAs/InP DHBTs with a thin heavily doped n-type InP layer at the base-collector interface was also demonstrated. It was shown that the energy barrier between the base and collector was effectively eliminated by a 3 nm thick n-type InP layer with ND=3×1019 cm−3. The DHBT devices with an emitter size of 2×12 μm2 showed fT > 80 GHz and BVceo > 9 V, which can be comparable to the results reported for DHBTs with a graded layer between the base and collector.

      • SCIESCOPUSKCI등재

        Bio-protective potential of lactic acid bacteria: Effect of Lactobacillus sakei and Lactobacillus curvatus on changes of the microbial community in vacuum-packaged chilled beef

        Zhang, Yimin,Zhu, Lixian,Dong, Pengcheng,Liang, Rongrong,Mao, Yanwei,Qiu, Shubing,Luo, Xin Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.4

        Objective: This study was to determine the bacterial diversity and monitor the community dynamic changes during storage of vacuum-packaged sliced raw beef as affected by Lactobacillus sakei and Lactobacillus curvatus. Methods: L. sakei and L. curvatus were separately incubated in vacuumed-packaged raw beef as bio-protective cultures to inhibit the naturally contaminating microbial load. Dynamic changes of the microbial diversity of inoculated or non-inoculated (control) samples were monitored at $4^{\circ}C$ for 0 to 38 days, using polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE). Results: The DGGE profiles of DNA directly extracted from non-inoculated control samples highlighted the order of appearance of spoilage bacteria during storage, showing that Enterbacteriaceae and Pseudomonas fragi emerged early, then Brochothrix thermosphacta shared the dominant position, and finally, Pseudomonas putida showed up became predominant. Compared with control, the inoculation of either L. sakei or L. curvatus significantly lowered the complexity of microbial diversity and inhibited the growth of spoilage bacteria (p<0.05). Interestingly, we also found that the dominant position of L. curvatus was replaced by indigenous L. sakei after 13 d for L. curvatus-inoculated samples. Plate counts on selective agars further showed that inoculation with L. sakei or L. curvatus obviously reduced the viable counts of Enterbacteraceae, Pseudomonas spp. and B. thermosphacta during later storage (p<0.05), with L. sakei exerting greater inhibitory effect. Inoculation with both bio-protective cultures also significantly decreased the total volatile basic nitrogen values of stored samples (p<0.05). Conclusion: Taken together, the results proved the benefits of inoculation with lactic acid bacteria especially L. sakei as a potential way to inhibit growth of spoilage-related bacteria and improve the shelf life of vacuum-packaged raw beef.

      • KCI등재

        Hydrothermal Hexagonal SrFe12O19 Ferrite Powders: Phase Composition, Microstructure and Acid Washing

        Ailin Xia,Xuzhao Hu,Diankai Li,Lu Chen,Chuangui Jin,Conghua Zuo,Shubing Su 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.2

        A series of hexagonal m-type SrFe12O19 ferrite powders were hydrothermally synthesized, and their phase composition, microstructure and magnetic properties before/after acid washing were studied. In the synthesis of these specimens, the atomic ratio of Fe/Sr (RF/S) in starting materials was set to 4, 5 and 12, respectively. When RF/S = 12, the specimen has morphology of round flat cakes, not typical hexagonal plate-like structure. The results of SEM images and XRD patterns indicate that the specimen with RF/S = 12 was mostly composed of Fe2O3. When RF/S = 4 or 5, the hexagonal plate-like SrFe12O19 ferrite powders were successfully synthesized with only a small quantity of Fe2O3 and SrCO3 impurities. It is also found that acid washing can eliminate the impurities in as-synthesized specimens effectively, and also change their topography, which enhances the saturation magnetization. However, the coercivity changed irregularly after acid washing, which is ascribed to the combination of the changed morphology, introduced stress and lattice defects.

      • KCI등재

        Protective Effects of Gypenosides against Fatty Liver Disease Induced by High Fat and Cholesterol Diet and Alcohol in Rats

        Renan Qin,Hong Nie,Jianyu Zhang,Chuyuan Li,Xiaoqi Zhang,Aihua Xiong,Feng Huang,Zhen Yin,Kongyan Li,Wenyu Qin,Mingzhen Chen,Shubing Zhang,Lingyi Liang,Huiye Zhang,Wencai Ye 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.7

        In the present study, the protective effects of gypenosides from Gynostemma pentaphyllum on fatty liver disease (FLD) were examined in rats treated with high fat and cholesterol diet and alcohol. Male SD rats were divided into seven groups: control, model, lovastatin, silymarin, gypenosides high-, medium- and low-treatment groups. The latter 6 groups were fed high-fat and cholesterol diet and administered alcohol intragastricly once a day. Body weight was measured every week for 10 weeks, and the hepatic index was measured after 10 weeks. Compared with model group, levels of serum triglyceride (TG), total cholesterol (TC), free fatty acid (FFA), and low density lipoprotein cholesterol (LDL-C) level, malondialdehyde (MDA), serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity, and hepatocyte apoptosis were significantly decreased in gypenosides groups; while serum high density lipoprotein cholesterol (HDL-C), superoxide dismutase (SOD) activity in both serum and hepatic tissue and mRNA and protein level of peroxisome proliferator-activated receptor α (PPAR-α) were significantly increased. Moreover, hepatic steatosis and mitochondrial damage were improved. These results suggested that gypenosides could prevent liver fatty degeneration in fatty liver disease through modulating lipid metabolism, ameliorating liver dysfunction and reducing oxidative stress.

      • A Chemical Chaperone-Based Drug Candidate is Effective in a Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

        Getter, Tamar,Zaks, Ilana,Barhum, Yael,Ben-Zur, Tali,,selt, Sebastian,Gregoire, Simpson,Viskind, Olga,Shani, Tom,Gottlieb, Hugo,Green, Omer,Shubely, Moran,Senderowitz, Hanoch,Israelson, Adrian,K Wiley (John WileySons) 2015 ChemMedChem Vol.10 No.5

        <P>Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective death of motor neurons and skeletal muscle atrophy. The majority of ALS cases are acquired spontaneously, with inherited disease accounting for only 10?% of all cases. Recent studies provide compelling evidence that aggregates of misfolded proteins underlie both types of ALS. Small molecules such as artificial chaperones can prevent or even reverse the aggregation of proteins associated with various human diseases. However, their very high active concentration (micromolar range) severely limits their utility as drugs. We synthesized several ester and amide derivatives of chemical chaperones. The lead compound 14, 3-((5-((4,6-dimethylpyridin-2-yl)methoxy)-5-oxopentanoyl)oxy)-N,N-dimethylpropan-1-amine oxide shows, in the micromolar concentration range, both neuronal and astrocyte protective effects in vitro; at daily doses of 10?mg?kg(-1) 14 improved the neurological functions and delayed body weight loss in ALS mice. Members of this new chemical chaperone derivative class are strong candidates for the development of new drugs for ALS patients.</P>

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