응급실에 내원한 국내 간질중첩증 소아의 발생율과 특성

신은주(Eun Ju Shin),황세희(Se Hee Hwang) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.1

Purpose: Status epilepticus (SE) is the most common life-threatening neurological condition in childhood. To clarify the incidence and outcome, we have evaluated the epidemiological and clinical characteristics of SE patients in Korea. Methods: In evaluating data from the National Emergency Department Information System (NEDIS), we retrospectively analyzed patients, and classified them by age and sex distribution, body temperature, time on arrival, seasonal variation and treatment outcome. The patients were under 8 years old who visited 111 general hospital emergency rooms in Korea between 2007 and 2013. Results: There were 4,257 total patients enrolled in our study. The ratio of males to females was 1.11:1. The incidence of SE in Korean children was 14.5/100,000 in 2010, and the highest incidence was seen in patients 1 to 2 years old. We could not find a seasonal variation. Febrile patients with temperatures over 38 °C accounted for 1,901 patients(44.7%). Peak time on arrival was 6 p.m. to midnight for 1,301 patients (30.5%). 3,356 patients (78.8%) were admitted immediately for proper treatment, while 678 patients(15.9%) were allowed to go home after emergency treatment. Unfortunately, 4 patients (0.1%) died despite first aid. Conclusion: The most common age in SE is 1 to 2 years. Regarding the correlation of fever with SE, patients who exhibit fever accounted for almost half of the patients with SE. In our study, the mortality rate in emergency room was 0.1%. Therefore, anyone who is suspected to have SE should be immediately transferred to a general hospital with ICU facilities for intensive treatment under the direction of medical experts.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

동·서양 고전에 나타난 도덕적 통념에 관한 비판적 해석 -『논어』와 『에우티프론』에 나타난 아버지를 고발한 아들의 사례를 중심으로-

임명희 ( Lim Myung Hee ),김세원 ( Kim Se Won ) 동양철학연구회 2017 東洋哲學硏究 Vol.89 No.-

본 논문은 동서양의 고전 문헌에서 도덕적 통념에 관한 문제가 어떻게 다루어졌는지 고찰한 것이다. 이를 위해 『논어』에 나타난 `곧음(直)`에 관한 공자와 제자들의 대화, 『에우티프론』에 나타난 `경건함(?σιον)`에 관한 소크라테스와 에우티프론의 대화를 각각 분석하고, 그 철학적 함의를 검토하였다. 이를 통해 본 논문은, 공자와 소크라테스가 특정 도덕적 딜레마나 그것의 해결책 또는 특정 도덕관념에 대한 정의 자체에 관심이 있었다기보다, 독단적 자기 확신 또는 도덕적 통념에 관한 비판적 해석에 주안점을 두고 있었다는 것을 주장하였다. 결론적으로, 이들 철학자들은 아버지를 고발한 아들이라는 사례를 통해 우리의 삶에서 도덕적 믿음에 대한 반성적 태도가 중요함을 강조하며, 그 과정은 타자와의 대화를 수반한다는 점을 보여주고자 한 것이라 볼 수 있다. The aim of this study is to examine an issue of moral beliefs and moral conceptions in the Eastern and Western Classics. This paper focuses on the texts with one specific common material. That is the son who accused the father in the Analects(Lunyu) and the Plato`s Euthyphron. Confucius has a conversation with his follower about `Zhi(直)` and Socrates makes dialectical arguments with Euthyphron about a definition of `piety(to hosion)`. The philosophers critically examine opinions of the opposing parties to support the accusation. Other papers studied on aspects of moral dilemma(the private or the public, Physis and Nomos) or relation of religion and philosophy. But the important problem is relation between rightness(or justice) and honesty. In conclusion, this paper illuminates that the philosophers emphasize personal moral beliefs and their reflective attitudes toward one` own and lives, rather than the dilemma`s solution or the definition of moral ideas per se. Also, it is necessarily that the reflective courses involve a conversation with others.

Association between Socioeconomic Status and Altered Appearance Distress, Body Image, and Quality of Life Among Breast Cancer Patients

Chang, Oliver,Choi, Eun-Kyung,Kim, Im-Ryung,Nam, Seok-Jin,Lee, Jeong Eon,Lee, Se Kyung,Im, Young-Hyuck,Park, Yeon Hee,Cho, Juhee Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Breast cancer patients experience a variety of altered appearance - such as loss or disfigurement of breasts, discolored skin, and hair loss - which result in psychological distress that affect their quality of life. This study aims to evaluate the impact of socioeconomic status on the altered appearance distress, body image, and quality of life among Korean breast cancer patients. Materials and Methods: A cross-sectional survey was conducted at advocacy events held at 16 different hospitals in Korea. Subjects were eligible to participate if they were 18 years of age or older, had a histologically confirmed diagnosis of breast cancer, had no evidence of recurrence or metastasis, and had no psychological problems at the time of the survey. Employment status, marital status, education, and income were assessed for patient socioeconomic status. Altered appearance distress was measured using the NCI's cancer treatment side effects scale; body image and quality of life were measured by the EORTC QLC-C30 and BR23. Means and standard deviations of each outcome were compared by socioeconomic status and multivariate linear regression models for evaluating the association between socioeconomic status and altered appearance distress, body image, and quality of life. Results: A total of 126 breast cancer patients participated in the study; the mean age of participants was 47.7 (SD=8.4). Of the total, 83.2% were married, 85.6% received more than high school education, 35.2% were employed, and 41% had more than $3000 in monthly household income. About 46% had mastectomy, and over 30% were receiving either chemotherapy or radiation therapy at the time of the survey. With fully adjusted models, the employed patients had significantly higher altered appearance distress (1.80 vs 1.48; p<0.05) and poorer body image (36.63 vs 51.69; p<0.05) compared to the patients who were unemployed. Higher education (10.58, standard error (SE)=7.63) and family income (12.88, SE=5.08) was positively associated with better body image after adjusting for age, disease stage at diagnosis, current treatment status, and breast surgery type. Similarly, patients who were married and who had higher education had better quality of life were statistically significant in the multivariate models. Conclusions: Socioeconomic status is significantly associated with altered appearance distress, body image, and quality of life in Korean women with breast cancer. Patients who suffer from altered appearance distress or lower body image are much more likely to experience psychosocial, physical, and functional problems than women who do not, therefore health care providers should be aware of the changes and distresses that these breast cancer patients go through and provide specific information and psychosocial support to socioeconomically more vulnerable patients.

특수 언어발달 장애 환아의 임상 및음향음성학적 특성연구

김연희,박세훈,신용일,김찬양,김현기,김정수 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.1

치과 교정학 분야에서 COMPUTER 이용에 관하여

경희문,권오원,배세복 대한치과교정학회 1989 대한치과교정학회지 Vol.19 No.3

About twenty years ago the computer was introduced into orthodontic, but not in clinics because it was inconvenient in cost, size, capacity and operation. But recent advances in the technology of electronics have produced a personal computer which is suitable for use in clinics. We have developed useful program for cephalometric Ax, model analysis and patient management. The computer program greatly aided in saving time & effort and performed well in the management & searching for patient data. But further studies about tree dimensional analysis, S.T.O. and derivation of automatic treatment planning from analysis are needed.

후방 도달 척추 절제술을 이용한 강직성 요천추 변형의 치료

석세일,정의룡,이정희,김진혁,김성수,이지호,최원기,박용원 대한척추외과학회 2004 대한척추외과학회지 Vol.11 No.2

鋼 熔着金屬의 熱變形脆化에 關한 硏究

鄭世喜,金台永,林載奎,鄭熙敦,朴昌彦 全北大學校 1984 論文集 Vol.26 No.-

The susceptibility of weld metal(AWS, F76-EH14) on hot straining embrittlement has been examined. The sharp notch was machined on the weld metal of 1st bead and on coarse-grained HAZ transformed by next pass. After machining the notch, these specimens were bended at 250℃ to receive the hot straining embrittlement and they were done COD fracture toughness test by the three point bending, and then the change of plastic zone at notch tip was evaluated by microhardness test. The obtained results are summarized as follows. 1. Fracture toughness of weld metal was greater than that of base metal. 2. Fracture toughness of the coarse-grained HAZ was similar to that of weld metal. 3. Hardness of weld metal reheated by next pass was lower than that of weld metal owing to the effect of heat treatment. 4. Plastic deformation of the coarse-grained HAZ was less than that of weld metal.

삼천포 화력발전소 연안의 플랑크톤상을 중심으로한 해양 환경

金世華,李晉煥,洪旭熹 龍仁大學校 1993 용인대학교 논문집 Vol.9 No.-

Impacts of the power plant operation located in the coastal area of Samchonpo were investgated in the view point of the population dynamics of zoo -and phytoplankton five times seasonally during the period from August 7 1990 to August 27 1991. Ninty nine taxa of phytoplankton, representing 2 forma, 1 variety, 79 species and 17 unidentified species belonging to 39 genera were tentatively identified. Phytoplankton standing crops varied with months and stations ranging from 5.8×104cells /l (November 1990, station 5) to 4.83×106cells /l (May 1991, station 4) in surface, ranging from 2.9×105cells /l (Novemver 1990, station 5) to 5.90×106cells /l (May 1991, station 4) in bottom. Dominant species through the present study were Chaetoceros compressus and C. curvisetus in August 1990, Nitzschia pungens in November, Eucampia zodiacus and Skeletonema costatum in February 1991, Leptocylindrus danicus in May, and S. costatum and S. tropicum in August. Causative organisms of red -tide due to diatoms were 24 taxa. Among them, six species occurred throughout the year ; Chaetoceros debilis, Cylindrotheca closterium, Guinardia flaccida, Nitzschia pungens, Rhizosolenia setigera and Skeletonema costatum. Chlorophyll -α was fluctuated ranging from 6.18mg /m3 (August 1990, station 1) to 23. 77mg /m3(February 1991, station 4) in surface, This value of chlorophyll -a might be assumed that eutrophication occurred in studied waters. Twenty two taxa of zooplankton communities, representing 14 copepods, 4 cladocerans, 2 chaetognaths, 1 protozoan and 1 appendicularian were identified. Zooplankton abundance varied with months and stations ranging from 1,677 indiv./m3 to 18,057 indiv./m3.

역사교육에서 '가학기술사' 교육의 의의와 교재 개발의 방향

장세옥,이명희 한국사회과교육연구학회 2004 사회과교육 Vol.43 No.1

본 연구에서는 과학기술사 교육을 역사교육에서 접근한다면 다음과 같은 의의가 있음을 고찰하였다. 첫째, 역사적 방법의 특성을 살려 종합적으로 접근함으로써 과학기술사의 내용과 발달과정 및 그 배경과 영향을 종합적으로 파악할 수 있다. 둘째, 근거에 입각하여 사실을 주장하고 판단하는 역사적 방법과 과학의 본질인 합리성을 통해 시민적 자질의 기초를 육성할 수 있다. 셋째, 과학기술을 삶과 분리된 현상으로서가 아니라 인간생활의 한 양식인 문화로 인식하는 데 유용하다. 넷째, 역사교육의 내용이 정치, 경제, 사회, 문화의 측면에서 선정되고 구성되는 종래의 틀에서 벗어나 과학기술의 내용과 발전 과정을 중요한 내용으로 다룸으로서 역사교육의 내용과 소재를 풍부하게 할 수 있다. 다섯째, 과학적 문제의 해결과정과 사고의 발전과정을 추체험적으로 이해함으로써 역사적 사고력을 효과적으로 육성할 수 있다. 그리고 역사교육에서 과학기술사 교재 개발은 다음과 같은 방향에서 이루어지는 것이 바람직함을 고찰하였다. 첫째, 과학기술의 내용과 발전 과정 및 그 영향을 당시의 역사적 배경과 더불어 종합적으로 접근한다. 둘째, 과학의 합리주의적 정신이 과학기술사를 통해 어떻게 실현되며 또 그것이 당시의 사회생활에 어떠한 변화를 초래하였는지를 역사적 사례를 근거로 활용하여 실감할 수 있도록 한다. 셋째, 역사적 상황과 현실 속에서 새로운 과학기술의 발명과 문제해결이 구체적으로 어떻게 진행되는지 그 사고의 과정을 추체험할 수 있도록 새로운 과학기술의 내용뿐만 아니라 이를 발명하고 이끌어간 사람들의 삶과 경험 등을 소재로 교재를 개발한다. 넷째, 과학기술사를 통해 역사의 핵심 개념인 '변화와 계속성', '원인과 결과'를 학습하여 궁극적으로 역사이해의 폭을 넓힐 수 있도록 교재를 개발한다. 다섯째, 과학기술을 잘못 사용하여 생긴 인류의 위기를 극복하기 위한 방안으로 인간·자연·과학기술이 공존하는 '생태학적 문화관'에 입각한 교재를 개발한다. This survey is to look over The Educational Meaning of Science- Technology History in History Education and The Guideline of Textbook Development, as a process of a textbook research in history education to teach 'Science-Technology History' effectively. Nowadays, Science-Technology History in Secondary class is to list only the events of Science-Technology, so it is difficult to comprehend the overall development of Science-Technology. There was no complete textbook and learning model used in the history class concerning the developmental stages, the contents of change, and the social influences of Science-Technology. In this respect, this survey is focused on the whole comprehension of Science-Technology, by enriching the contents as culture, by reflecting the historical and social changes, and by combining mult7i-discipline. The Education of Science-Technology History can be expected to be most effective in history class than any other class due to its overall comprehension, and can be helpful for growing up the scientific rationality, one of the democratic Qualities. In addition, teaching materials are enriched by adding Science- Technology to culture. The Guideline of Textbook Development is as follows; to comprehend the whole social phenomena related with Science-Technology; to get the experience shared in the past by re-enactment; to comprehend the main concept of history such as 'change and continuity' and 'cause and effect'; and finally to develop the textbook in terms of 'Physiological Culture' to coexist with Science-Technology.