광범위 세공 피복 대퇴 주대를 사용한 고관절 재치환술의 단기 추시 결과 보고

문경호,강준순,조규정,이동주,정새롬 대한고관절학회 2004 Hip and Pelvis Vol.16 No.1

단풍취 분획물이 알콜대사효소에 미치는 영향

문형인,지옥표,문세훈,신말식 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

Spraque-Dawley계 수컷랫트에 계통분획한 단풍취의 각 분획물을 경구투여하고 혈청 ethanol농도와 간의 ADH활성에 미치는 효과를 검색 추적한 결과 알코올대사를 촉진시키는 성분은 주로 에탄올가용부에, 억제시키는 성분은 에탄올불용부에 주로 존재함을 추정할 수 있었고 현재 활성성분을 분리중에 있다.(1998년 9월 25일 접수, 1998년 10월 14일 수리) Effects of organic solvents fraction from Ainsliaea acerifolia ethanol extract on alcohol metabolism in rats were examined and the results were as follows: Ethanol souble fraction, after a single oral administration to rats, was found to cause a significant decrease in the serum ethanol concentration as well as enhancement of liver cytosolic alcohol dehydrogenase(ADH) activity, on the other hand, the fraction insouble in ethanol was found to cause an increase ethanol concentration in the blood and inhibit ADH activity.

대학 교양체육 교육과정의 편성과 운영 개성에 관한 연구

文世榮,金尙圭 연세대학교 대학원 1986 延世論叢 Vol.22 No.1

This study aims at not only establishing programs for the purpose of the efficient composition of curriculums to cultural gymnastics, but also seeking after a substantial plan of cultural gymnastics for the sake of efficiency in a cultural education which is required by the present society. The objects of study consist in 383 students at "Y" university & 417 female students at "E"University, existing in Seoul, and they were attending a lecture about the cultural gymnastics at the time when the questionnaires were drawn up. And the conclusions of this study was as follows: 1. In the greatest reason that they are now choosing the course of cultural gymnastics, 63% of male students and 61.4% of sophomores, juniors and seniors selected its course due to their taste, and 80.8% of female students and 77.5% of freshmen chose its course due to convenience in a subject or a schedule. 2. In the satisfied degree which they are presently attending a lecture to cultural gymnastics, sophomores, juniors and seniors of male students show their satisfactions at 71.7%; female students, 40.6%;Freshmen, only 41.8%. 3. As for assistant instructors, 64.4% of male students and 61.1% of sophomores, juniors and seniors want to be in need of assistant instructors, and 54.9% of female students and 56.4% of freshmen do so as well. 4. If choosing cultural gymnastics again, what they wish most is tennis first on the list at all groups 5. As for the questionnaire of whether or net the present facilities and circumstances for cultural gymnastics are enough to carry out its course, all the groups respond to 'No' consistently.

畓裏作 麥類 機械收穫方法 確立에 關한 硏究 : Ⅲ. 團地條件에 따른 콤바인 作業精度와 收穫粒의 品位에 關하여 Ⅲ. Combine Harvesting Workability and Grain Quality under Different Harvesting Field Conditions

李康世,朴文洙 群山大學校自然科學硏究所 1987 自然科學硏究 Vol.2 No.-

올밀의 栽培圃場에서 콤바인收穫當時의 栽培條件을 달리하여 作業能率, 損失量, 穀粒品位등을 檢討하였던바 그 結果를 要約하면 다음과 같다. 1. 콤바인을 利用할 경우 出穗後 44日頃이 收穫適期에 해당되나 乾燥劑를 處理하면 慣行區의 收穫適期(40日)까지 앞당길 수 있었다. 2. 콤바인收穫區는 慣行收穫區에 비하여 收穫作業時間이 85%절감되었으나 收穫損失率은 4.2%(26-31kg/10a)를 보여 4倍까지 增加되었다. 특히 雜草放任區와 아침刈取區에서 損失量이 현저하였다. 3. 콤바인收穫區는 慣行收穫區에 비하여 5%程度, 倒伏區, 아침刈取區, 乾燥劑處理區는 各各의 對照區에 비하여 2∼4% 減收되는 경향이었다. 4. 미탈부율은 콤바인 收穫區에서 2%미만을 보여 慣行收穫區의 5.7%보다 양호하였으며 특히 雜草放任區(3.8%)와 아침刈取區(4.5%)에서 높아 穀粒의 品位가 低下되었다. 5. 雜草放任區의 減收率은 12%로서 生育初期의 둑새풀(9%)과 生育後期의 갈퀴덩굴(3%)에 起因하는 것으로 분석되었다. This experiment was conducted to determine the effects of different harvesting field conditions on the working ability of Combine and the loss and quality of wheat grain. Harvesting working time by Combine required for only 15 percentage of conventional conduct, but grain loss marked 26-31 kg/10a and it was as much as forth times against conventional conduct. However grain yield by Combine harvesting only reduced by 5% as compared to conventional, but there was no statistical significant. And grain quality was good because the fine grain degree has over 98%.

요로감염증 환자의 치료에서 메로페넴(Meropenem)과 이미페넴/실라스타틴(Imipenem/Cilastatin)의 임상효과 및 안정성

김세웅,이승주,이지열,조용현,신완식,윤문수 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 :메로페넴은 실라스타틴을 복합투여하지 않아도 되는 새로운 계열의 카바페넴계 항생물질이다. 요로감염 치료에 있어서의 메로페넴의 효과와 안전성을 평가하기 위하여 기존의 카바페넴계 항생물질인 이미페넴/실라스타틴과 동시에 비교임상실험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법을 통하여 시행하였다. 1996년 10월부터 1998년 2월까지 가톨릭대학교 의과대학 부속 성모병원 및 울산대학교 외과대학 부속 중앙병원 비뇨기과에 입원한 신우신염과 복잡성방광염 환자 115명을 대상으로 하였고, 연속적 무작위 배정방법을 통하여 메로페spa군 58명과 이미페넴/실라스타틴군 57명으로 분류하였다. 두가지 약제는 모두 0.5 g을 12시간 간격으로 정맥주사 하였고, 평균 투약기간은 4일 (3-8일) 이었다. 임상효과, 세균학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 67명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 메로페넴군은 34명이었고, 이미페넴/실라스타틴군은 33명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 메로페넴투여군은 34례중 32례 (94.1%)에서, 이미페넴/실라스타틴투여군은 33례중 29례 (87.9%)에서 유효율을 보였다. 세균학적 평가에서 메로페넴 투여군은 34례중 32례 (94.1%)에서, 이미페spa/실라스타틴투여군은 33례중 29례 (87.9%)에서 세균학적 소실율을 보였다. 세균학적 재발 은 각각 4명과 7명이 나타났고, 재감염은 메로페넴군은 나타나지 않았지만, 이미페넴/실라스타틴군은 2명이 나타났다. 임상효과와 세균학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 부작용은 메로페spa투여군 56례중 1례 (1.8%)에서, 이미페넴/실라스타틴투여군 53례중 1례 (1.9%)에서 나타났으며, 임상검사치 이상은 메로페넴투여군 45례중 10례 (22.2%)에서, 이미페넴 실라스타틴투여군 44례중 8례 (18.2%)에서 나타났으나 전체적으로 특별히 문제가 된 증례는 없었다. 결론 :결론적으로 메로페spa은 신우신염 및 복잡성방광염과 같은 요로감염에 대하여 이미페넴/실라스타틴과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Metopenem is the first of a new class carbapenems which may be administered without cilastatin. The clinical study was carried out to assess efficacy and safety of metopenem in the treatment of urinary tract infections, in comparison to imipenem/cilastatin. Methods : This was a controlled, two-center, prospective, randomized study with two parallel groups. From October 1996 until February 1998, a total of 115 consecutive patients with urinary tract infections, such as pyeolonephritis and complicated cystitis, were randomly allocated into two groups, 58 in the meropenem group and 57 in the imipenem/cilastatin group. Both drugs were administered intravenously, at a dose of 0.5 g every 12 hours. The mean duration of therapy was 4 days (3-8 days) for both treatment. Clinical and bacteriological reponses were assessed at the begining of treatment, during treatment, at the end of treatment, and follow-up (1-2 weeks). Results : A total of 67 patients, 34 of meropenem and 33 of imipenem/cilastatin, were evaluable for response. Overall, a positive clinical response (recovery and improvement) was observed in 32 (94.1%) of 34 patients treated with meropenem and in 29 (87.9%) of 33 patients with imipenem/cilastin and the corresponding eradication rates of the primary pathogens were 32 (94.1%) of 34 patients and 29 (87.9%) of 33 patients, respectively. The microbiological relapse after the treatment completion was recorded in 4 patients treated with meropenem and 7 patients given imipenem/cilastath and superinfections occurred in none and 2 patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. Both drugs were well tolerated with adverse events considered to be related to therapy being recorded for 1 (1.8%) of 56 patients treated with meropenem and 1 (1.9%) of 53 of those who had been given imipenenjcilastatin. Conclusion : Empirial monotherapy with meropenem was therefore as effective and as well tolerated as that with imipenem/cilastatin for the treatment of urinary tract infections.

급성 단순하부요로감염증 치료에서 노르플록사신과 루플록사신의 임상효과 및 안전성

김세웅,이지열,이승주,조용현,윤문수 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

목적 : 루플록사신은 긴 반감기와 넓은 항균력을 가진 퀴놀론계 항생물질이다. 급성 단순하부요로감염 치료에 있어서의 루플록사신의 효과와 안전성을 평가하기 위하여 기존의 퀴놀론계 항생물질인 노르플록사신과 비교임상시험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법으로 진행하였으며 1997년 8월부터 1999년 3월까지 가톨릭대학교 의과대학 부속 성모병원 비뇨기과에 내원한 급성 단순하부요로감염 환자 72명을 대상으로 하였다. 연속적 무작위 배정방법을 통하여 루플록사신군 36명과 노르플록사신군 36명이 루플록사신 400㎎을 단회 경구투여 받거나 노르플록사신 400㎎을 12시간 간격으로 3일간 6회 경구투여 받았다. 임상효과, 미생물학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 64명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 루플록사신군은 32명이었고, 노르플록사신군은 32명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 루플록사신투여군은 32례중 32예(100%)에서, 노르플록사신투여군은 32례 중 31례(96.9%)에서 만족할 만한 결과를 얻었다. 미생물학적 평가에서 루플록사신투여군은 32례 중 29례(90.6%)에서, 노르플록사신투여군은 32례 중 28례(87.5%)에서 미생물학적 소실을 보였다. 미생물학적 재발은 루플록사신군과 노르플록사신군에서 각각 1례(3.1%)과 2례(6.3%)가 나타났고, 재감염은 각각 2례(6.3%)와 1례(3.1%)가 나타났다. 임상효과와 미생물학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 약물역동학적 검사상 루플록사신은 노르플록사신에 비해 높은 MIC를 갖고 있지만 긴 반감기를 통해 소변내에서 높은 농도와 요 살균력을 유지함을 알 수 있었다. 부작용은 루플록사신투여군 34례 중 5례(14/7%)에서, 노르플록사신투여군 35례 중 1례(2.9%)에서 나타났으며, 대부분의 소화기계통의 이상반응 이었으며, 모두 경증으로 24시간 이내에 소실되었다. 루플록사신투여군 중 2례에서는 경증의 중추신경계의 이상반응이 관찰되었다. 결론 : 결론적으로 루플록사신은 급성 단순하부요로감염에 대하여 1회 투여만으로도 노르플록사신의 3일 투여법과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Rufloxacin is a broad-spectrum quinolone that exhibits a prolonged elimination half-life. The purpose of this study is to evaluate the efficacy and safety of a single dose of rufloxacin, campared with those of a norfloxacin standard treatment. Methods : This was a open. randomized. parallel-group, phase 11 clinical trial. A total of 72 women with acute lower urinary tract infections were included and randomly assigned to one of the treatment regimens: rufloxacin 400㎎ single dose, or norfloxacin 400㎎ b.i.d. for 3 days. Clinical and bacteriological assessments were performed twice at the third day and the seventh or tenth day after inclusion. Results : A total of 64 patients(32 and 32 patients in the rufloxacin and norfloxacin groups, respectively) were considered clinically and bacteriologically evaluable. Overall, a clinical response(recovery and improvement) was observed in 32 (100%) of 32 patients treated with rufloxacin and in 31 (96.95) of 32 patients with norfloxacin. The corresponding eradication rates of the primary pathogens were 90.6%(29/32) and 87.5%(28/32), respectively. The microbiological relapses between the seventh and tenth day were recorded in 1 patient(3.1%) and 2 patients(6.3%) in the rufloxacin and norfloxacin groups, respectively. The superinfections occurred in 2(6.3%) and 1(3.1%) patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. The pharmacodynamic evaluation showed similar median urine bactericidal titers(UBT) for both treatment groups against initial isolates, despite a higher MIC of rufloxacin than that of norfloxacin. Five patients (14.7%) in the rufloxacin group and 2 patients (5.7%) in the norfloxacin group reported 9 and 4 adverse events, respectively, almost all of them being mild and lasting <24 h. Overall, gastrointestinal reactions were the most frequent adverse events reported. However, 2 patients treated with rufloxacin reported 3 central nervous system adverse events. Conclusion : This study suggests that single dose of rufloxacin treatment is effective and well tolerated as norfloxacin 3-day standard treatment in acute uncomplicated lower urinary tract infections.

지대별 가시오갈피의 광합성 반응

이강세,현동윤,박문수,김선 군산대학교 기초과학연구소 2000 基礎科學硏究 Vol.15 No.-

We determined the most adapted area as measured leaf function and chlorophyⅡfluorescence with a long-term on leaflets of Kasiogalpi (Eleutherococcus senticosus Mas) plants grown in Iksan, Changge and Mt. Chiri. 1. In area of Iksan and Changge, during the day, rate of CO2 assimilation was highest at ante meridiem, and it was not coincide with transpiration. But transpiration was generally coincide with highest light intensity and leaf temperature. When compared CO2 assimilation at each area, Changge showed highly pronounced diurnal fluctuation throughout season, but Mt. Chiri remaining low level without obvious fluctuation during the day. 2. The time-course of PAR (photon active radiation) and leaf temperature at each area was observed differently. Among areas, it showed substantially higher at Iksan than at relatively high attitude area (Mt. Chiri). 3. ChlorophyⅡ fluorescence, i.e., Fo, Fm and Fv/Fm were not different in compared Iksan with Changge. But at Mt. Chiri, it was higher than at any other areas.

뇌동맥류 수술후 원격부위에 발생한 뇌실질내 출혈

박상준,오세문,신동익,박세혁 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

거대 수신증 3예

이규백,문장호,이순호,김세철 중앙대부설한국의과학연구소 1983 한국의과학 Vol.15 No.4

음낭 Sparganosis 1예

소병억,김유찬,문장호,이순호,김세철 중앙대부설한국의과학연구소 1983 한국의과학 Vol.15 No.4