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[P132] White papules on the chest
( Geun-hwi Park ),( Sung-min Park ),( Hyun-joo Lee ),( Hyunju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Fibroelastolytic papulosis (FEP) encompasses a spectrum of two disorders that were previously reported as pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and white fibrous papulosis of the neck (WFPN). It is characterized by asymptomatic, non-confluent, non-follicular and firm papules occurring predominantly on the neck in elderly individuals. FEP on upper chest without involving the neck have been rarely reported. A 81-year-old female patient presented with an increasing number of asymptomatic white papules on her chest for the past 6 months. Histopathologic evaluation showed decreased and fragmented elastic fibers without dermal fibrosis in upper dermis. There was no past history of vascular, gastrointestinal or ocular disorders and no family history of similar skin lesions. Our patient showed clinical characteristics resembling WFPN, and histologic findings similar to that of PXE-PDE. Therefore, we diagnosed her as FEP. There had been no change in the lesions on follow up 6 months later. Although it had been reported that WFPN occurred on the neck or trunk including neck, this case suggests that this condition also can occur on only chest without involving the neck Through this case, in the investigation of white papules on localized area of the chest, FEP should be included in the differential diagnosis.
Lee, Hyang-Ah,Park, Joon Ha,Kim, Dae Won,Lee, Choong-Hyun,Hwang, In Koo,Kim, Hyeyoung,Shin, Myoung Cheol,Cho, Jun Hwi,Lee, Jae-Chul,Noh, Yoohun,Kim, Sung-Su,Won, Moo-Ho,Ahn, Ji Hyeon SPANDIDOS PUBLICATIONS 2018 MOLECULAR MEDICINE REPORTS Vol.17 No.3
<P>Oligodendrocytes are myelin-forming cells in the central nervous system. Research into the effects of aging on oligodendrocyte protein expression remains limited. The present study aimed to determine the alterations in oligodendrocyte-specific protein (OSP) expression in the gerbil hippocampus at 1, 2, 3, 4, 6 and 24 months of age with western blot and immunohistochemistry analyses. OSP expression levels in the hippocampus were highest at 6 months of age. OSP immunoreactivity was identified in numerous cell bodies at 1 month, although the number of OSP immunoreactive cells was different according to hippocampal subregion. The number of OSP immunoreactive cells significantly decreased at 2 months and, thereafter, numbers decreased gradually. The detection of OSP immunoreactive fibers was negligible in all layers in the hippocampal subregions until 4 months. OSP immunoreactive fibers were abundant at 6 and 24 months, although the fiber distribution patterns in the CA1-3 areas and dentate gyrus were different. The results demonstrated that OSP expression in the gerbil hippocampus was age-dependent. The detection of OSP immunoreactive cell bodies and fibers was significantly different according to the layers of hippocampal subregions, indicating that myelination may be continuously altered in the hippocampus during normal aging.</P>
( Geun-hwi Park ),( Hyang-suk Ryu ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Dermatofibroma is fibrohistiocytic tumor of the skin, commonly occurs as a solitary lesion on the lower extremities of young women. Multiple eruptive dermatofibromas (MEDFs), defined as presence of 5 to 8 dermatofibromas appearing within a period of 4 months, are rare and etiology of MEDFs is still unknown. However, they are frequently thought to be associated with altered immunity, such as autoimmune diseases and immunosuppression. It is unclear why MEDFs occur in association with these conditions, but this relationship may suggest that MEDFs are the result of an abortive immunoreactive process. We herein describe a middle-aged women who developed multiple dermatofibroma. She had myasthenia gravis for 8 years, and developed MEDFs after undergoing oral corticosteroid treatment (245 mg/wk) for 3 months. Therefore, our case could attribute to theory that using immunosuppressants works more dominant factor on occurrence of MEDFs than underlying immune disease.
Kim, Jin Hwi,Choi, Ji Hyang,Ki, Eun Young,Lee, Sung Jong,Yoon, Joo Hee,Lee, Keun Ho,Park, Tae Chul,Park, Jong Sup,Bae, Seog Nyeon,Hur, Soo Young BMJ 2012 International journal of gynecological cancer Vol.22 No.4
<P>This study aimed to determine the incidence and risk factors of lower-extremity lymphedema (LEL) in women who had radical surgery with or without adjuvant radiotherapy for International Federation of Gynecology and Obstetrics (FIGO) stage I to stage IIA cervical cancer.</P>
스마트폰 기반 HMD 환경에서 VR 콘텐츠의 유형이 저연령 학습자의 사용자 경험에 미치는 영향
이지향(Ji-Hyang Lee),서민휘(Min-Hwi Seo),계보경(Bo-Kyung Kye),소효정(Hyo-Jeong So) 한국HCI학회 2017 한국HCI학회 학술대회 Vol.2017 No.2
가상현실(VR) 기술의 발전과 더불어 스마트폰 기반 HMD 를 활용한 가상현실 콘텐츠가 조만간 교육현장에 도입 및 확산될 것으로 예상되고 있으나, 효과적인 교육용 VR 콘텐츠 유형의 본질 및 이에 따른 사용자 경험에 대한 연구는 부족한 것이 현실이다. 따라서 본 연구는 VR 콘텐츠 유형이 저연령(만 12 세미만) 학습자의 사용자 경험에 미치는 영향을 탐색하고자 하였다. 이를 위해 초등학교 사회과 ‘이웃나라’ 단원의 수업을 위해 시각적 구현방식이 다른 사진 기반 VR 콘텐츠와 동영상 기반 VR콘텐츠를 활용하여, 두 가지 다른 콘텐츠 유형이 저연령 사용자의 가상현실 기반 학습 경험에 미치는 영향을 탐색하였다. 초등학생 45 명을 대상으로 실험을 실시하였으며, 연구결과 사진 기반 VR콘텐츠의 용이성 및 만족도가 동영상 기반 VR 콘텐츠보다 유의미하게 높은 것으로 나타났다. 본 연구는 교육용으로 제작되는 VR 콘텐츠의 경우 몰입감 증진을 위한 시각적 구현 방식과 학습자 경험간에 상충(trade-off) 관계가 있을 수 있음을 제시한다.
김휘준,배정찬,김도향,Kim, Hwi-Jun,Bae, Jung-Chan,Kim, Do-Hyang 한국분말야금학회 2006 한국분말재료학회지 (KPMI) Vol.13 No.6
본고에서는 고유한 원자구조에 기인한 우수한 특성으로 인해 구조재료 및 기능재료로서 그 활용이 기대되고 있는 벌크 아몰퍼스 소재에 있어 온간압출, 온간압연, 방전 플라즈마 소결(Spark Plasma Sintering)등 과냉각액체온도구간에서의 점성유동을 이용한 고화성형 공정의 최근 기술동향에 대해 간략히 소개했다.