Highly-sensitive Detection of Salvianolic Acid B using Alumina Microfibers-modified Electrode

Dong Sun,Xiaoyong Zheng,Xiafeng Xie,Xiaofeng Yang,Huajie Zhang 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.11

Alumina microfibers with porous structures were prepared through hydrothermal reaction, and then used to modify the surface of carbon paste electrode (CPE). After modification with alumina microfibers, the electrochemical activity of CPE was found to be greatly improved. On the surface of alumina microfibersmodified CPE, the oxidation peak current of salvianolic acid B, a main bioactive compound in Danshen with anti-oxidative and anti-inflammatory effects, was remarkably increased compared with that on the bare CPE surface. The influences of pH value, amount of alumina microfibers and accumulation time were studied. Based on the strong signal amplification effects of alumina microfibers, a novel electrochemical method was developed for the detection of salvianolic acid B. The linear range was from 5 μg L−1 to 0.3 mg L−1, and the detection limit was 2 μg L−1 (2.78 nM) after 1-min accumulation. The new method was successfully used to detect salvianolic acid B in ShuangDan oral liquid samples, and the recovery was over the range from 97.4% to 102.9%.

Microstructures and Mechanical Properties of Equiatomic NiTi Shape Memory Alloy Undergoing Local Canning Compression and Subsequent Annealing

Dong Sun,Shuyong Jiang,Xiaodong Xing,Bingyao Yan,Junbo Yu,Yanqiu Zhang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12

Local canning compression is imposed on equiatomic NiTi shape memory alloy (SMA) with complete B19′ martensite. Afraction of retained nanocrytalline grains are embedded in the dominant amorphous phase. The compressed NiTi samples areannealed for 2 h at various temperatures, including 300, 450 and 600 °C. Grain size increases with increasing crystallizationtemperature during heat treatment. Under annealing at 300 °C, nanocrystalline grains are dominant in NiTi SMA, where thereexists local amorphous zone. Under annealing at 450 °C, almost complete nanocrystalline can be obtained. Under annealingat 600 °C, grain size increases substantially, but there still exists a small amount of nanocrystalline grains. Under annealingat 300 °C, NiTi SMA exhibits extremely high elastic limit, but its plasticity is poor. Under annealing at 450 °C, NiTi SMAexhibits very high yield stress and it simultaneously keeps high plasticity. Under annealing at 600 °C, NiTi SMA exhibitsrelatively low yield stress, but its yield stress is still higher than that of as-received NiTi SMA and its plasticity is also high.

혁신학교가 초등학교 교사의 소진에 미치는 영향

김동선 ( Kim¸ Dong Sun ),홍창남 ( Hong¸ Chang Nam ) 부산대학교 과학교육연구소 2020 교사교육연구 Vol.59 No.4

이 연구는 혁신학교가 초등학교 교사의 소진에 미치는 영향을 분석하는 데 목적이 있다. 이를 위해 부산교육연구정보원의 「부산교육종단연구(BELS)」 3차년도 초등학교 교사, 학교, 교장 자료를 분석에 활용하였다. 혁신학교가 교사 소진에 미치는 영향을 분석하기 위해 선행연구를 통해 도출된 교사 소진에 영향을 미치는 학교 및 교사 수준 변인을 통제한 후, 위계적 선형 모형(HLM)을 활용하여 분석하였다. 주요 연구 결과를 요약하면 다음과 같다. 첫째, 기초모형 분석 결과, 교사 소진이 학교 간에 의미 있는 차이가 있는 것으로 분석되었다. 둘째, 혁신학교가 교사 소진을 의미 있게 낮추는 것으로 나타났다. 이러한 연구 결과는 혁신학교 성과의 한 단면을 보여주는 것으로, 교사 업무 경감을 위해 혁신학교가 지원한 각종 지원책들의 실질적인 효과가 간접적으로 검증된 것이라 할 수 있다. The purpose of this study was to analyze the effects of innovation schools on teacher burnout. The third year data of Elementary teachers, schools, and principals in the Busan Education Longitudinal Study (BELS) was used to analyze the data using the Hierarchical Linear Model (HLM). The main results of this study are as follows. Firstly, the difference in teacher burnout between schools was verified when analyzing the basic model of HLM with teacher burnout as the dependent variable. Secondly, innovation schools had a lower rate of teacher burnout. The results of this study show one aspect of the achievements of innovation schools, and it can be said that the practical effects of various support provided by innovation schools to reduce the teacher’s workload was indirectly verified.

불교상담에서의 자기연민 프로그램의 가치

최동선 ( Choi¸ Dong-sun ) 동아시아불교문화학회 2021 동아시아불교문화 Vol.- No.47

본 연구에서는 자기연민 개념의 불교상담적 배경을 살펴보고 자기연민 프로그램이 갖는 치유적 가치를 논의하고자 하였다. 자기연민은 불교의 자리이타(自利利他) 사상의 바탕이 되는 불교적 정서로서 심리적 어려움에 놓인 자신과 타인을 동시에 구제할 수 있는 치유적 개념이다. 초기불교에서 대승불교에 이르기까지 자기연민은 불교적 자비심과 불가분의 관계에 놓여있다. 초기불교의 사무량심은 자(慈), 비(悲), 희(喜), 사(捨)를 통해 한량없는 중생에 대한 연민을 담고 있다. 대승불교에서 보살의 자비심은 중생구제의 실천적인 과제를 수행하기 위해서는 고난에 처한 중생에 대한 정서적 공감과 자애의 감정이 수반되어야 한다. 어려움을 겪는 이들이 고통에서 벗어나기를 간절하게 바라는 마음이 곧 중생을 구제하는 수행으로 이어질 수 있다는 것이다. 자기연민에 의한 수행은 단지 고통에서 벗어나거나 치유하는 데서 그치지 않고 치유 이후의 성장에 주목하는 점에서 일반적인 치유와 차이가 있다. 본 연구에서는 자기연민을 활용한 대표적인 명상프로그램으로서 MSC의 사례에 주목하였다. MSC는 기존의 마음챙김 기반 프로그램(MBSR)에 자기연민의 내용을 강화시켜 8단계의 명상 프로그램으로 구성되어 있다. 8회기에 걸친 과정들을 단계별로 명목화 한다면 각각 동기유발 단계, 알아차림 단계, 정서순화 단계, 심층정서 단계, 목표인식 단계, 정서수용 단계, 관계직면 단계, 행복배양 단계로 설명될 수 있다. 이들 단계에서는 각각 자기연민이 요구되는 조건과 실제적인 치유 활동으로 구성되고 있다. 자기연민을 통한 불교 상담의 연구는 서구의 심리치료와 같은 맥락에 있으나 치료를 넘어서 불교적 수행의 단계로 끌어 올릴 수 있는 계기가 될 수 있기를 기대한다. This study tried to examine the Buddhist counseling background of the concept of self-compassion and to discuss the healing value of the self-compassion program. Self-compassion is a Buddhist emotion that is the basis of the Buddhist ideas of Self-Benefit and Benefit for Others(自利利他). It is a healing concept that can rescue oneself and others from psychological difficulties at the same time. Buddhist meditation and healing programs(MBSR, MBCT, DBT, ACT. MSC), which are actively developed and used in the West, are recognized for their value through the verification of clinical effects. All of these programs have in common the use of Buddhist concepts of mindfulness and self-compassion in psychotherapy, and pursue the practical benefits of Buddhist meditation by excluding religious characteristics. From early Buddhism to Mahayana Buddhism, self-compassion is inextricably linked with Buddhist compassion for Sentient Beings(衆生). In early Buddhism, as Four Unlimited Hearts, maitrī(慈), karuņā(悲), muditā(喜), and upekșā(捨,) contained compassion for infinite sentient beings. In Mahayana Buddhism, the compassion of a bodhisattva must be accompanied by emotional empathy and loving-kindness toward beings in hardship in order to carry out the practical task of salvation for all living things. It is said that the earnest desire for those who are suffering to be free from suffering can lead to the practice of saving Sentient Beings. The practice of self-compassion differs from general healing in that it focuses on growth after healing rather than just getting out of pain or healing. This study focused on the case of MSC as a representative meditation program using self-compassion. MSC consists of an 8-step meditation program by strengthening the content of self-compassion in the existing Mindfulness-Based Program (MBSR). If the processes over the eight sessions are nominally staged, they can be explained as the motivational stage, the awareness stage, the emotional purification stage, the deep emotional stage, the goal recognition stage, the emotional acceptance stage, the relationship facing stage, and the happiness culturing stage. Each of these stages consists of a condition that requires self-compassion and a practical healing activity. The core skills of these stages are mind-calmness, mindfulness, and self-compassion, which are ways to reduce anxiety and stress while leading to satisfaction and peace. The study of Buddhist counseling through self-compassion is in the same context as Western psychotherapy, but it is expected that it will serve as an opportunity to elevate it to the stage of Buddhist practice beyond treatment.

Role of corticosteroids in stress-induced alteration of blood-brain barrier permeability

Dongsun park,Jeong Hee Jeon,Sunhee Shin,Jae Hong Choi,Bong Ho Choi,Yun-Bae Kim 한국실험동물학회 2007 한국실험동물학회 학술발표대회 논문집 Vol.2007 No.-

Which Crashes Should I Fix First?: Predicting Top Crashes at an Early Stage to Prioritize Debugging Efforts

Dongsun Kim,Xinming Wang,Sunghun Kim,Zeller, A,Cheung, S C,Sooyong Park IEEE 2011 IEEE transactions on software engineering Vol.37 No.3

<P>Many popular software systems automatically report failures back to the vendors, allowing developers to focus on the most pressing problems. However, it takes a certain period of time to assess which failures occur most frequently. In an empirical investigation of the Firefox and Thunderbird crash report databases, we found that only 10 to 20 crashes account for the large majority of crash reports; predicting these “top crashes” thus could dramatically increase software quality. By training a machine learner on the features of top crashes of past releases, we can effectively predict the top crashes well before a new release. This allows for quick resolution of the most important crashes, leading to improved user experience and better allocation of maintenance efforts.</P>

Where Should We Fix This Bug? A Two-Phase Recommendation Model

Dongsun Kim,Yida Tao,Sunghun Kim,Zeller, Andreas IEEE 2013 IEEE transactions on software engineering Vol.39 No.11

<P>To support developers in debugging and locating bugs, we propose a two-phase prediction model that uses bug reports' contents to suggest the files likely to be fixed. In the first phase, our model checks whether the given bug report contains sufficient information for prediction. If so, the model proceeds to predict files to be fixed, based on the content of the bug report. In other words, our two-phase model 'speaks up' only if it is confident of making a suggestion for the given bug report; otherwise, it remains silent. In the evaluation on the Mozilla 'Firefox' and 'Core' packages, the two-phase model was able to make predictions for almost half of all bug reports; on average, 70 percent of these predictions pointed to the correct files. In addition, we compared the two-phase model with three other prediction models: the Usual Suspects, the one-phase model, and BugScout. The two-phase model manifests the best prediction performance.</P>

Anti-hypercholesterolemic and anti-atherosclerotic effects of polarized-light therapy in rabbits fed a high-cholesterol diet

Dongsun Park,Jangbeen Kyung,Dajeong Kim,Seock-Yeon Hwang,Ehn-Kyoung Choi,Yun-Bae Kim 한국실험동물학회 2012 Laboratory Animal Research Vol.28 No.1

The effects of polarized-light therapy (PLT) on high-cholesterol diet (HCD)-induced hypercholesterolemia and atherosclerosis were investigated in comparison with that of lovastatin in rabbits. Hypercholesterolemia was induced by feeding male New Zealand white rabbits with 1% cholesterol in diet for 2 weeks and maintained with 0.5% cholesterol for 6 weeks, followed by normal diet for 2 weeks for recovery. Lovastatin (0.002% in diet) or daily 5-min or 20-min PLT on the outside surface of ears was started 2 weeks after induction of hypercholesterolemia. Hypercholesterolemic rabbits exhibited great increases in serum cholesterol and low-density lipoproteins (LDL) levels, and finally severe atheromatous plaques formation covering 57.5% of the arterial walls. Lovastatin markedly reduced both the cholesterol and LDL, but the reducing effect (47.5%) on atheroma formation was relatively low. By comparison, 5-min PLT preferentially decreased LDL, rather than cholesterol, and thereby potentially reduced the atheroma area to 42.2%. Notably, 20-min PLT was superior to lovastatin in reducing both the cholesterol and LDL levels as well as the atheromatous plaque formation (26.4%). In contrast to the increases in blood alanine transaminase and aspartate transaminase following lovastatin treatment, PLT did not cause hepatotoxicity. In addition, PLT decreased platelets and hematocrit level. The results indicate that PLT attenuates atherosclerosis not only by lowering blood cholesterol and LDL levels, but also by improving blood flow without adverse effects. Therefore, it is suggested that PLT could be a safe alternative therapy for the improvement of hypercholesterolemia and atherosclerosis.

Application of Automated Watering System to guinea pigs housed in the open cage system

Dongsun Kim,Yonggi Jang,Bunyoun Dong 한국실험동물학회 2016 한국실험동물학회 학술발표대회 논문집 Vol.2016 No.2

Hybrid Channel Estimatation Method Using Decision-directed and Pilot-assisted CSI for OFDM Systems

Dongsun Kim,Jungwook Wee,Jungwook Seo,Wongi Jeon,Jintae Kim,Jongho Baek 대한전자공학회 2005 ITC-CSCC :International Technical Conference on Ci Vol.2005 No.2