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최준희 ( Joon Hee Choi ),전지승 ( Ji Sung Chun ),설정은 ( Jung Eun Seol ),황선욱 ( Seon Wook Hwang ),성호석 ( Ho Suck Sung ),이드보라 ( Deborah Lee ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.10
Eruptive vellus hair cyst (EVHC) is a benign epithelial tumor. Clinically, it usually presents as grouped or scattered yellowish to reddish-brown papules. It predominantly appears on the anterior part of the chest and extremities. Facial involvement is uncommon and 4 cases with facial involvement have been reported in the Korean dermatologic literature. However, involvement of the face coexistent with involvement of the trunk and extremities has never been reported in the Korean dermatologic literature. Herein, we report on a 10-year-old girl with multiple asymptomatic papules on her face, back and upper arms. To the best of our knowledge, this is the first report of EVHC that involves not only the face, but also the trunk and extremities in the Korean dermatologic literature. (Korean J Dermatol 2009;47(10):1154∼1157)
보툴리눔 독소와 미세침 전기응고술로 병합치료한 다발성 에크린 한선낭종
최준희 ( Joon Hee Choi ),심현수 ( Hyun Soo Sim ),정윤 ( Yoon Jung ),성기한 ( Kee Han Seung ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.10
Multiple eccrine hidrocystomas are benign cysts of eccrine duct and occur mainly in middle aged women with numerous translucent papules on the central face. The treatment of multiple eccrine hidrocystomas is difficult because of their numbers and location. We propose a combined therapeutic method of botulinum toxin and electrosurgery for widely spreading eccrine hidrocystomas. Botulinum toxin inhibits sweating by temporarily blocking the release of acetylcholine from cholinergic neurons that innervate sweat glands. Electrosurgical energy is transmitted along cystic fluid and destructs cystic walls. A 62-year-old woman presented with multiple translucent papules on the face and was diagnosed with multiple eccrine hidrocytomas. Electrocoagulation was performed at a low power setting on the whole face and botulinum toxin was injected intradermally for microcystic lesions on the whole face except upper eyelids. The condition was controlled successfully for 4 months. We think that botulinum toxin and fine needle electrocoaglation are effective treatments for multiple eccrine hidrocytomas. (Korean J Dermatol 2007;45(10):1090∼1092)
최준희 ( Joon Hee Choi ),이현재 ( Hyun Jae Lee ),정소영 ( So Young Jung ),서종근 ( Jong Keun Seo ),이드보라 ( Deborah Lee ),황선욱 ( Seon Wook Hwang ),성호석 ( Ho Suck Sung ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.2
Superficial acral fibromyxoma is a rare, distinctive soft tissue neoplasm most often located in the periungal region of the fingers and toes. This tumor was recently recognized as a distinct clinicopathological entity and since then quite a few cases have been reported. These tumors are composed of stellate and spindle cells arranged in a loose form, with a fascicular growth pattern, and occur mostly in middle-aged adults. However in our case, the lesion developed in 9-year-old male, who had a history trauma. Although the exact pathogenesis of superficial acral fibromyxoma has not yet been clarified, it is possible that the fibroblast hyperplasia in the lesion could be triggered by trauma. We suggest this case which occurred in a 9-year-old patient, triggered by trauma, is a peculiar and interesting event. (Korean J Dermatol 2010;48(2):123∼126)
순차적 레이블링을 위한 ACE와 Self-Attention을 활용한 인공 신경망에 관한 연구
이종민(Jong-Min Lee),최준희(Joon-Hee Choi) 한국지능시스템학회 2021 한국지능시스템학회논문지 Vol.31 No.2
최근 자연어 처리 분야의 순차적 레이블링을 위해 복수의 단어 임베딩 모델과 Recurrent Neural Network(RNN) 기반의 순차 모델을 이용한 인공 신경망이 보편적으로 사용되고 있다. 이로 인해 신경망 모델에 적합한 임베딩 벡터의 결합을 찾는 것과 순차 모델의 역전파 과정 중 발생하는 기울기 소실 문제를 해결하는 것은 중요한 연구 주제가 되었다. 본 논문은 복수의 임베딩 벡터들 중 일부를 사용하여 최적의 임베딩 결합을 찾는 Automated Concatenation of Embeddings(ACE)와 기울기 소실 문제를 해결하기 위해 셀프 어텐션을 활용하는 방법을 제안한다. 제안 방식의 성능을 검증하기 위해 순차적 레이블링 문제의 일종인 품사 태깅과 개체명 인식에서 다양한 데이터셋을 사용해 실험을 수행하였다. 그 결과 현재 최고의 성능을 내는 논문의 모델들 보다 향상된 성능을 보인다. Recently multiple word embedding models and sequence models based on RNN have been widely used for sequence labeling in the field of natural language processing. It is essential to find optimal embedding vectors for concatenation. Also, we should address the vanishing gradient problem during the backpropagation. This paper proposes a method using self-attention and ACE for solving the problems. We verified the performance of our proposed method on datasets for sequence labeling such as part of speech tagging and named entity recognition. Our proposed model shows better performance than the state of the art models.
서종근 ( Jong Keun Seo ),최준희 ( Joon Hee Choi ),이상민 ( Sang Min Lee ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2007 대한피부과학회지 Vol.45 No.2
Cytophagic histiocytic panniculitis gap (CHP) was described in 1980 as a chronic histiocytic disease of the subcutaneous tissue and associated with systemic manifestations such as fever, serositis, and hepatosplenomegaly. The current concept of CHP is that it represents a spectrum of lymphoproliferative disorders that induce secondary histiocytic cytophagocytosis. The pathogenesis of hemophagocytosis in CHP is unknown but may be related to histiocyte reaction to an abnormal cytokine milieu brought about by disordered T-cell function. In most cases the disease follows a fulminant course, but in some patients the disease seems limited to the skin and subcutaneous tissue and follows a more benign, chronic course. We report a case of cytophagic histiocytic panniculitis which had a long chronic course over 16 years, but recently became aggravated with the involvement of the extrapleural fat tissue and was treated with combination chemotherapy. (Korean J Dermatol 2007;45(2):180~184)
건초 섬유종과 유사한 조직소견을 보인 건초 거대세포 종양 1예
서종근 ( Jong Keun Seo ),최준희 ( Joon Hee Choi ),정윤 ( Yun Jeong ),이숙경 ( Sook Kyung Lee ) 대한피부과학회 2007 大韓皮膚科學會誌 Vol.45 No.6
Giant cell tumor of the tendon sheath and fibroma of the tendon sheath are similar benign neoplasms occurring near or within joints. The cells of giant cell tumor of the tendon sheath may be related to synovial cells, monocytes, and osteoclasts, whereas those of fibroma of the tendon sheath show myofibroblastic differentiation. But some authors consider these tumors to be different stages of the same pathologic process; fibroma of the tendon sheath is probably one end of the morphological spectrum of regression of giant cell tumor of the tendon sheath. We report a case of giant cell tumor of the tendon sheath with histologic findings similar to that of fibroma of the tendon sheath and suggest some fibroma of the tendon sheaths are indeed the end sclerosing stage of giant cell tumor of tendon sheaths. (Korean J Dermatol 2007;45(6):640∼643)
이숙경 ( Sook Kyung Lee ),정윤 ( Yun Jeong ),최준희 ( Joon Hee Choi ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.10
Background: Nipple and areola diseases of the breast cause cosmetic, sexual and functional problems, and these problems are important to most patients, so awareness of these disease entities is invaluable. Still, there has been insufficient clinical investigation of these condit-ions. Objective: This study was performed to investigate the epidemiological aspects of nipple and areola diseases that were confirmed by biopsies, and we wanted to highlight the clinical features of dermatoses of the nipple and areola. These disease features were then compared between the patients who visited the Departments of Dermatology and General Surgery. Methods: We retrospectively reviewed the data of 80 patients with nipple and areola lesions and these lesions were confirmed by biopsy at Maryknoll Hospital between March 1989 and August 2007. 37 patients visited the Department of Dermatology and 43 patients visited the Department of General Surgery. Results: The ratio of males to females was 6: 74. The ratio of the males to females seen at the Department of Dermatology was 6: 31. In contrast, that of the patients seen at the Department of General Surgery was 0: 43. The most frequent nipple and areola skin diseases were fibroadenoma, intraductal papilloma, accessory breast and nipple eczema in the decreasing order of frequency. The most frequent nipple and areola skin diseases seen at the Department of Dermatology were nipple eczema, soft fibroma, hyperkeratosis of the nipple and areola, Paget`s disease and invasive ductal carcinoma in the decreasing order of frequency. In contrast, the most frequent nipple and areola skin diseases seen at the Department of General Surgery were fibroadenoma, intraductal papilloma, accessory breast, phyllodes tumor and subareolar abscess. Of the 80 cases, 49 had papules or nodules, 15 had patches or plaques, 10 had vesicles, erosions or ulcers and 6 had nipple discharge. Of the 37 cases seen at the Department of Dermatology, 15 had patches or plaques, 14 had papules or nodules and 8 had vesicles, erosions or ulcers. In contrast, of the 43 cases seen at the Department of General Surgery, 35 had papules or nodules, 6 had bloody or serous nipple discharge, and 2 had vesicles, erosions or ulcers. Conclusion: We retrospectively studied 80 cases of nipple and areola skin diseases. This study suggests that various conditions, including dysembryoplasia, inflammatory dermatoses, hyperkeratoses and neoplasm, can affect the nipple and areola and show different characteristics according to the Hospital Department they are seen at. The patients with symptoms of patches or plaques tend to visit the Department of Dermatology. In contrast, patients with symptoms of papules or nodules tend to visit the Department of General Surgery. Further investigation with a large group of patients is necessary to better understand the epidemiology of nipple and areola skin diseases. (Korean J Dermatol 2008;46(10):1309∼1320)