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정성진,이긍주,이혜정,김진백,김동섭,강시용,Chung, Sung-Jin,Lee, Geung-Joo,Lee, Hye-Jung,Kim, Jin-Baek,Kim, Dong-Sub,Kang, Si-Yong Korean Society of Horticultural Science 2010 원예과학기술지 Vol.28 No.5
스프레이 국화 'Argus'의 꽃잎으로부터 $DgLDOX$의 전장 cDNA와 genomic DNA를 분리하였고, 감마선 변이원으로부터 유래된 3가지 화색변이체 사이의 다양한 유전자 특성들을 밝혀냈다. cDNA 영역은 1068bp이고 356 amino acid로 변환되었다. Genomic DNA의 크기는 'Argus'에서 1346bp이었고, 3가지 화색 변이체에서는 1363부터 1374의 크기를 나타내었다. $DgLDOX$ 유전자는 두 개의 엑손 사이에 하나의 인트론을 갖고 있는 구조이고, 그 크기는 'Argus'에서 112bp 이지만 3가지 화색 변이체에서는 128 혹은 137bp였다. 이것은 감마선 조사에 의해 인트론 부분에 유전자가 삽입됐다는 것을 나타낸다. DNA 분석 결과 국화의 게놈 내에서는 하나의 $LDOX$ 유전자를 갖는 것이 확인되었다. $DgLDOX$ 유전자의 발현 정도를 분석한 결과, 연분홍의 'Argus'와 두 개의 보라색 변이체(AM1 and AM3) 에서 높게 발현되었으나 흰색 변이체(AM2)에서는 매우 약하게 발현되었다. 이러한 결과들은 $DgLDOX$ 유전자의 인트론에 삽입된 유전자 조각 혹은 엑손 부위의 일부 아미노산의 변화에 의해서 변이체의 화색이 변할 수 있다는 것을 보여주고 있다. A full-length cDNA and genomic DNA of a $leucoanthocyanidin$ $dioxygenase$ ($DgLDOX$) gene was isolated from the petals of chrysanthemum 'Argus', and comparative features of the gene among three flower color mutants derived from a gamma-ray mutagenesis were characterized. The cDNA coding region of the gene was 1068 bp and was translated into 356 amino acids accordingly. The genomic DNA size was 1346 bp for 'Argus', while three mutants revealed ranges of 1363 to 1374 bp. A single intron between two coding exons for the $DgLDOX$ gene was found, of which size was 112 bp for 'Argus', but 128 or 137 bp for three flower color mutants, indicating that a genomic insertion in the intron occurred during the gamma-ray mutagenesis. DNA blot analysis revealed the $DgLDOX$ gene presenting as a single copy in the chrysanthemum genome. The $DgLDOX$ gene was expressed in both 'Argus' of light-pink color and two purple color mutants (AM1 and AM3) but had very weak expression in only white color mutant (AM2). The results demonstrated that variations in the flower color of the mutants might be associated with changes in the amino acid moieties in the coding exons or fragment insertions in the intron of the $DgLDOX$ gene, which potentially resulted in less expression of the gene in the white colored mutant.
기독교 신앙과 심리학의 조화로운 관계 탐색: 재림교회를 중심으로
정성진(Chung Sung-Jin) 삼육대학교 신학연구소 2018 신학과 학문 Vol.22 No.-
Although there have been many studies on the relationship between Christianity and psychology, there is little research on how to understand psychology in the Adventist church in Korea. The purpose of this study was to summarize the overseas studies related to the perspectives of the Adventists on psychology and to suggest future research directions. First, the researcher explained the relationships between Christianity and psychology by dividing them into confrontation type, subordination type, discrimination type, and integration type and stressed the necessity of integration. Second, by summarizing the Adventist’s position on psychology, present the belief in harmony of science and the Bible and Ellen White’s perspectives, and then summarized the activities and conclusions of the Committee on Adventist Approach to Psychology. Third, psychological studies on Adventists were summarized by the theme of Adventist Youth, Health Recognition of Adventists, and Mental Health of Adventists. Finally, it suggested the necessity of carrying out various studies on psychology from the perspective of Christian worldview and Adventist viewpoint
일차진료에서 흔히 접하는 수분 전해질 문제 ; 안지오텐신 전환효소 억제제/안지오텐신 수용체 차단제 사용과 고칼륨혈증
정성진 ( Sung Jin Chung ),박철휘 ( Cheol Whee Park ) 대한내과학회 2011 대한내과학회지 Vol.80 No.1
Therapeutic manipulation of the renin-angiotensin-aldosterone system (RAAS) is an important strategy for improving hypertension, diabetes, cardiovascular disease, and chronic kidney disease. Development of hyperkalemia after the administration of RAAS inhibitors is of particular concern because patients at highest risk for this complication are often the same patients who derive the greatest cardiovascular or renoprotective benefit. Based on an overview of the incidence of hyperkalemia during treatment with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers alone and in combination, this review suggests approaches for monitoring, detecting, and managing hyperkalemia in patients treated with RAAS inhibitors. Although the incidence of hyperkalemia with RAAS inhibitors is generally low, hyperkalemia can be associated with increased mortality. When using RAAS inhibitors, it is important to monitor on-treatment electrolyte levels and renal function parameters in patients with a high risk for hyperkalemia. (Korean J Med 2011;80:20-30)
한국판 가해행동 대인동기 척도(TRIM-12-K)의 타당화 연구
정성진 ( Sung Jin Chung ) 글로벌기독교세계관학회 2011 학문과기독교세계관 Vol.2 No.-
The current study was aimed to evaluate reliability and validity of the Transgression-Related Interpersonal Motivation inventory-12-Korean. 313 adults and college students responded to TRIM-12-K, FS(Forgiveness), KFS(Forgiveness), STAXI(anger), STAI (anxiety), and CES-D (depression). Exploratory and confirmatory factor analyses results supported two-factor(avoidance and revenge) model same as original TRIM-12. Internal consistencies for subscales of the TRIM-12-K were acceptable. Significantly high negative correlation between TRIM-12-K and FS and between TRIM-12-K and KFS indicated convergent validity. TRIM-12-K was positively associated with anger, anxiety, or depression as indices of psychological maladjustment. Theses findings suggest that the TRIM-12-K is valid and reliable to assess a degree of forgiveness. Limitations and suggestions for future research were discussed.