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- 저자 : ( Juan Xiang ) (검색결과 61 건)
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Xiang, Juan,Liu, Zhiming,Song, Taeseup Elsevier 2018 ELECTROCHIMICA ACTA Vol.283 No.-
<P><B>Abstract</B></P> <P>Hierarchical iron sulfide nanocubes consisting of multiple iron sulfide-carbon core-shell nanoparticles coated with few-layer graphene (Fe<SUB>1-x</SUB>S@C/rGO) were prepared by a two-step <I>in-situ</I> transformation strategy employing Prussian blue (PB) as a starting material. The hierarchical nanocubes delivered an outstanding rate capability of 323 mAh g<SUP>−1</SUP> at the current density of 10 A g<SUP>−1</SUP> when used as the anode of sodium ion half cells. An iron-based sodium-ion full cell composed of a hierarchical Fe<SUB>1-x</SUB>S@C/rGO anode and PB cathode had a capacity of 323 mAh g<SUP>−1</SUP> for 150 cycles. We attributed the good sodium ion storage properties of the Fe<SUB>1-x</SUB>S@C/rGO nanocubes to the stable hierarchical building structures and the high graphitization degree of carbon obtained during the transformation process. The graphene-coated nanocube structures inhibited the agglomeration of iron sulfide-carbon core-shell nanoparticles and accommodated the huge volume expansion that occurred during cycling. The high graphitization degree of carbon endowed Fe<SUB>1-x</SUB>S@C/rGO nanocubes with high electronic conductivity, facilitated sodium ion accessibility, and increased mechanical durability.</P>
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Fructus mume Protects Against Cigarette Smoke Induced Chronic Cough Guinea Pig
Juan Xiang,Xiaodong Liu,Shan Zhong,Zhangfu Fang,Shuirong Shen,Jiaman Tang,Siqi Lai,Kefang Lai 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.2
Fructus mume was recorded in the Chinese Pharmacopoeia and traditional Chinese medical books for chronic cough, but the effect and related constituents are still unknown. Thus, we investigated the protect effects and the relevant constituents of F. mume in a guinea pig model with chronic cough induced by cigarette smoke (CS). The organic acids and polysaccharides in F. mume were detected by high performance liquid chromatography, gel permeation chromatography, and gas chromatography–mass spectrometry. The guinea pigs were orally administered with vehicle or the water extract of Fructus mume (FW) during the 14 days of CS exposure. Citric acid induced coughs were automatically measured by Buxco system. The differential cells in bronchoalveolar lavage fluid (BALF) and histopathological changes in lung tissue were assessed by hematoxylin and eosin staining. The tumor necrosis factor alpha (TNF-α) and interleukin-8 (IL-8) levels in lung tissue were detected via enzyme-linked immunosorbent assay. The mucus productions in tracheas were determined with Alcian blue-periodic acid Schiff staining. The results suggested relatively high concentration of citric acid, chlorogenic acid, and neochlorogenic acid in F. mume, and high proportion of galactose and glucose and lower molecular weight of polysaccharides. Administration of FW significantly reduced the cough frequency, decreased inflammatory cells in BALF and lung tissue, and attenuated the thickening of airway epithelium and submucosa compared with CS-exposure group. Moreover, the overproduction of TNF-α and IL-8 in lung tissues, and mucus in central airways of CS-induced guinea pigs was markedly inhibited by FW. The extract could also protect against CS exposure-induced chronic cough in guinea pigs by reducing coughs, airway inflammation, and mucus overproduction.
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Xiang, Juan,Liu, Zhiming,Song, Taeseup Elsevier 2018 JOURNAL OF ALLOYS AND COMPOUNDS Vol.768 No.-
<P><B>Abstract</B></P> <P>Bismuth sulfides (Bi<SUB>2</SUB>S<SUB>3</SUB>) are potential electrode materials that have a high theoretical capacity for both lithium and sodium ion batteries. To better utilize the material in practical applications, it is urgent to solve the problem of severe capacity decay caused by low electronic conductivity and large volume change during cycling. Introducing graphene into the system would effectively alleviate these issues on account of the good electrical conductivity, high mechanical flexibility, and large surface area possessed by graphene. However, it is difficult to wrap Bi<SUB>2</SUB>S<SUB>3</SUB> with a graphene layer due to the intrinsic hydrophobicity of graphene layers and the strong π-interaction of graphene nanosheets. In this work, sandwich-like graphene-Bi<SUB>2</SUB>S<SUB>3</SUB> hybrids (rGO@Bi<SUB>2</SUB>S<SUB>3</SUB>) are synthesized from two-dimensional (BiO)<SUB>2</SUB>CO<SUB>3</SUB> nanosheets (BOC NSs) by electrostatic self-assembly and a subsequent sulfidation process with the assistance of a cationic surfactant. The electrostatic force provides an efficient approach for graphene layers to wrap well around BOC NSs to form a sandwich-like structure that can be retained after the sulfidation process. Benefitting from the merits of high electronic conductivity, robust structure stability, and sufficient space for volume expansion, the as-obtained rGO@Bi<SUB>2</SUB>S<SUB>3</SUB> hybrids show both high capacity and cycle stability as the anode of lithium/sodium ion batteries.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel sandwich-like rGO@Bi<SUB>2</SUB>S<SUB>3</SUB> nanostructures was synthesized from 2D (BiO)<SUB>2</SUB>CO<SUB>3</SUB>. </LI> <LI> Good compatibility of Bi<SUB>2</SUB>S<SUB>3</SUB>/rGO was achieved with the help of electrostatic force. </LI> <LI> Improved lithium/sodium storage properties were delivered by the rGO@Bi<SUB>2</SUB>S<SUB>3</SUB> hybrid. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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( Xiang Juan Gai ),김한승 ( Han Seung Kim ) 대한상하수도학회 2006 공동추계 학술발표회 논문집 Vol.2006 No.-
A submerged flat-sheet membrane separation system integrated with PAC (powdered activated carbon) was used in this research in order to investigate the effects of PAC on the efficiencies of operation and treatment and to evaluate the performance of the system. The experiments were carried out under operating conditions of a filtration rate of 0.38 m/d, water temperature of 20-28℃, and PAC dose of 0 g/L (Run-A) and 20 g/L (Run-B). The influent concentrations of TOC (total organic carbon), NH4(+)-N (ammonia nitrogen) and UV254 (UV absorbance at 254 nm) were 2.48 ㎎/L, 1.4 ㎎/L and 2.53 l/m, respectively. TOC removal of 43.2 and 73.6%, ammonia nitrogen removal of 4.9 and 15.9%, and UV254 removal of 20.6 and 31.6% were obtained for Run-A and Run-B, respectively. During an experimental period of 33 days, no change was found in TMP (Run-B), but the TMP in Run-A increased by 5 kPa after 29 days. This research showed that the filtrate quality and the performance efficiency were enhanced when PAC was introduced into the filtration system.
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Effect of Fermentation Conditions on L-Lactic Acid Production from Soybean Straw Hydrolysate
( Juan Wang ),( Qunhui Wang ),( Zhong Xu ),( Wenyu Zhang ),( Juan Xiang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.1
Four types of straw, namely, soybean, wheat, corn, and rice, were investigated for use in lactic acid production. These straws were mainly composed of cellulose, hemicellulose, and lignin. After pretreatment with ammonia, the cellulose content increased, whereas the hemicellulose and lignin contents decreased. Analytical results also showed that the liquid enzymatic hydrolysates were primarily composed of glucose, xylose, and cellobiose. Preliminary experiments showed that a higher lactic acid concentration could be obtained from the wheat and soybean straw. However, soybean straw was chosen as the substrate for lactic acid production owing to its high protein content. The maximum lactic acid yield (0.8 g/g) and lactic acid productivity (0.61 g/(l/h)) were obtained with an initial reducing sugar concentration of 35 g/l at 30°C when using Lactobacillus casei (10% inoculum) for a 42 h fermentation period. Thus, the experimental results demonstrated the feasibility of using a soybean straw enzymatic hydrolysate as a substrate for lactic acid production.
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( Xiang Juan Gai ),김한승 ( Han Seung Kim ) 한국물환경학회 ( 구 한국수질보전학회 ) 2006 공동 추계학술발표회 Vol.2006 No.-
A submerged flat-sheet membrane separation system integrated with PAC (powdered activated carbon) was used in this research in order to investigate the effects of PAC on the efficiencies of operation and treatment and to evaluate the performance of the system. The experiments were carried out under operating conditions of a filtration rate of 0.38 m/d, water temperature of 20-28℃, and PAC dose of 0 g/L (Run-A) and 20 g/L (Run-B). The influent concentrations of TOC (total organic carbon), NH4(+)-N (ammonia nitrogen) and UV254 (UV absorbance at 254 nm) were 2.48 ㎎/L, 1.4 ㎎/L and 2.53 l/m, respectively. TOC removal of 43.2 and 73.6%, ammonia nitrogen removal of 4.9 and 15.9%, and UV254 removal of 20.6 and 31.6% were obtained for Run-A and Run-B, respectively. During an experimental period of 33 days, no change was found in TMP (Run-B), but the TMP in Run-A increased by 5 kPa after 29 days. This research showed that the filtrate quality and the performance efficiency were enhanced when PAC was introduced into the filtration system.
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Juan Feng,Xiang Li,Xiaolan Yang,Chun Zhang,Yonghua Yuan,Jun Pu,Yunsheng Zhao,Yanling Xie,Huidong Yuan,Youquan Bu,Fei Liao 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.11
The use of uricase-deficient mammals to screen formulations of engineered uricases as potential drugs for hyperuricemia involves heavy costs and presents a technical bottleneck. Herein, a new practical system was investigated to evaluate the pharmacological significance of a bacterial uricase based on its ability to eliminate uric acid in plasma in vitro, its pharmacokinetics in vivo in healthy rats, and the modeled pharmacodynamics in vivo. This uricase, before and after modification with the monomethyl ether of poly(ethylene glycol)-5000, effectively eliminated uric acid in vitro in rabbit plasma, but its action was susceptible to xanthine inhibition. After intravenous injection of the modified uricase without purification, a bi-exponential model fit well to uricase activities in vivo in the plasma of healthy rats; the half-life of the modified uricase was estimated without interference from the unmodified uricase leftover in the sample and was nearly 100-fold longer than that of the unmodified uricase. Using a model of the elimination of uric acid in vivo taking into account of uricase pharmacokinetics and xanthine inhibition, modeled pharmacodynamics supported that the half-life of uricase and its susceptibility to xanthine are crucial for the pharmacological significance of uricase. Hence,this practical system is desirable for doing preliminary screening of formulations of engineered uricases as potential drugs for hyperuricemia.
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Xiang Xu,Yu-Nan Lu,Jia-Hui Cheng,Hui-Wen Lan,Jing-Mei Lu,Guang-Nan Jin,Guang-Hua Xu,Cheng-Hua Jin,Juan Ma,Hu-Nan Piao,Xuejun Jin,Lian-Xun Piao 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.1
Background: Maternal Toxoplasma gondii (T. gondii) infection during pregnancy has been associated with various mental illnesses in the offspring. Ginsenoside Rh2 (GRh2) is a major bioactive compound obtained from ginseng that has an anti-T. gondii effect and attenuates microglial activation through toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-kB) signaling pathway. GRh2 also alleviated tumor-associated or lipopolysaccharide-induced depression. However, the effects and potential mechanisms of GRh2 on depression-like behavior in mouse offspring caused by maternal T. gondii infection during pregnancy have not been investigated. Methods: We examined GRh2 effects on the depression-like behavior in mouse offspring, caused by maternal T. gondii infection during pregnancy, by measuring depression-like behaviors and assaying parameters at the neuronal and molecular level. Results: We showed that GRh2 significantly improved behavioral measures: sucrose consumption, forced swim time and tail suspended immobility time of their offspring. These corresponded with increased tissue concentrations of 5-hydroxytryptamine and dopamine, and attenuated indoleamine 2,3-dioxygenase or enhanced tyrosine hydroxylase expression in the prefrontal cortex. GRh2 ameliorated neuronal damage in the prefrontal cortex. Molecular docking results revealed that GRh2 binds strongly to both TLR4 and high mobility group box 1 (HMGB1). Conclusion: This study demonstrated that GRh2 ameliorated the depression-like behavior in mouse offspring of maternal T. gondii infection during pregnancy by attenuating the excessive activation of microglia and neuroinflammation through the HMGB1/TLR4/NF-kB signaling pathway. It suggests that GRh2 could be considered a potential therapy in preventing and treating psychiatric disorders in the offspring mice of mothers with prenatal exposure to T. gondii infection.
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Sensor fault diagnosis for bridge monitoring system using similarity of symmetric responses
Xiang Xu,Qiao Huang,Yuan Ren,Dan-Yang Zhao,Juan Yang 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.23 No.3
To ensure high quality data being used for data mining or feature extraction in the bridge structural health monitoring (SHM) system, a practical sensor fault diagnosis methodology has been developed based on the similarity of symmetric structure responses. First, the similarity of symmetric response is discussed using field monitoring data from different sensor types. All the sensors are initially paired and sensor faults are then detected pair by pair to achieve the multi-fault diagnosis of sensor systems. To resolve the coupling response issue between structural damage and sensor fault, the similarity for the target zone (where the studied sensor pair is located) is assessed to determine whether the localized structural damage or sensor fault results in the dissimilarity of the studied sensor pair. If the suspected sensor pair is detected with at least one sensor being faulty, field test could be implemented to support the regression analysis based on the monitoring and field test data for sensor fault isolation and reconstruction. Finally, a case study is adopted to demonstrate the effectiveness of the proposed methodology. As a result, Dasarathy’s information fusion model is adopted for multi-sensor information fusion. Euclidean distance is selected as the index to assess the similarity. In conclusion, the proposed method is practical for actual engineering which ensures the reliability of further analysis based on monitoring data.
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