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      • KCI등재후보

        산모혈과 제대혈에서 연농도에 관한 조사

        이덕희,문종국,배강우,이용환,김진하,박강원 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.3

        This study was conducted to evaluate the blood lead levels in 141 pregnant women who were not occupationally exposed to lead and their umbilical cord, and to identify some differences in blood lead levels by living area. The subjects were all delivered at St. Benedict Hospital in Pusan and the blood lead levels were measured by graphite furance atomic absorption spectrophotometer. The summarized results were as follows. 1. The geometric mean lead levels in maternal and cord blood were 8.0±1.8μg/dl, 5.0±0.6μg/dl respectively. 2. Lead levels in maternal(8.7±1.7μg/dl) and cord blood(5.4μ±0.7μg/dl) of industrial area(n=24) were higher than residential area(n=124) which were 7.9±1.7μg/dl and 5.0±0.6μg/dl respectively(p<0.05). 3. Maternal blood lead concentration was significantly correlated to cord blood lead concentration(r=0.6090, p<0.001), but other variables(maternal age, paternal smoking, birth weight, etc) were not correlated.

      • KCI등재

        일 대학병원에서 양극성장에 환자의 흡연 특성 : 정신분열병 환자와의 비교 연구

        이강수,천덕희,김지혜,김현진,조현상 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

        Objectives : This study aimed to investigate smoking characteristics and nicotine dependence severity in bipolar disorder Comparing those of schizophrenia. Methods : 70 bipolar and 123 schizophrenic patients, diagnosed using DSM-IV-TR criteria and treated at the Severance Mental Health Hospital, were interviewed regarding socio-demographic variables, smoking characteristics and Fagerstrom Test for Nicotine Dependence (FTND), designed to evaluate the intensity of smoking. Results : The rate of current smoking was 60.0% in the bipolar group, and 50.4% in the schizophrenia group. No significant difference was seen in terms of the rate of current smoking between the groups. Rates of having ever smoked also did not differ between bipolar (73%) and schizophrenic patients (65%). Daily cigarette consumption of bipolar patients (15.9 cigarettes/day) was significantly lower than that of schizophrenic patients (21.2 cigarettes/day), but FTND score didn't appear to differ between bipolar and schizophrenic patients. Bipolar females showed higher rate of current smoking (44%) than schizophrenic females (17%). Among bipolar patients, antipsychotics dose was not correlated with daily cigarette consumption and FTND total score. Age of disease onset didn't appear to differ between smokers and non-smokers in bipolar group. Conclusion : Although daily consumption was significantly lower in the bipolar group, the rate of smoking and smoking severity in bipolar disorder were as high as in schizophrenia. This fact suggests that the bipolar disorder might be related to the nicotinic acetylcholine system dysfunction as like schizophrenia.

      • KCI등재후보

        소아 혈중 연농도에 관한 조사

        이용환,이덕희,김진하,박인근,한태영,장세한 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

        지리적 위치에 따라 소아들에 있어서 혈중 연농도에 차이가 있는지의 여부와 소아들의 혈중 연농도의 참고치 계산을 위한 기초자료를 얻기 위하여 6-8세의 도심지역 거주 소아 102명과 교외지역 거주 86명, 총 188명을 대상으로 조사하여 다음과 같은 결과를 얻었다. 1. 전체 소아들의 평균혈중 연농도는 산술평균이 7.24, 기하평균이 6.92 ㎍/100㎖이었으며 남자가 여자보다 통계적으로 유의하게 더 높았다(p<0.05). 2. 도심지역과 교외지역 거주 소아들의 혈중 연농도는 도심지역거주 소아가 남, 녀 모두에서 교외지역 거주 소아보다 통계적으로 유의하게 더 높았다(p<0.05). 3. 혈중 연농도에 따른 분포에서는 <5 ㎍/100㎖군에 조사대상자 188명의 17.02%가 분포되었고 도심지역(5.88%)보다 교외지역(30.23%)에서 더 많은 분포를 보였으며, 10 ㎍/100㎖이상 군에는 전체 소아의 12.23%가 분포하고 있었으며, 도심지역(20.59%)이 교외지역(2.33%)보다 더 많이 분포하고 있었다. 이상의 결과에서 볼 때 도심지역 거주 소아들에 대한 연폭로의 관리대책이 시급히 마련되어야 할 것으로 판단된다. The authors conducted this study to evaluate some differences in blood lead levels between inner-city and suburban children and obtain the basic data of the reference value of the blood lead concentrations in children. The subjects were composed of 102 children residing in inner-city and 86 children in suburban. Their age range were 6 to 8 years old and the obtained results were as follows; 1. The arithmetic means of the blood lead level in male and female, male, and female children were 7.24, 7.40, 7.08 ㎍/100㎖, and geometric means were 6.92, 7.08, 6.76㎍/100㎖, respectively. 2. The children residing in inner-city had the higher blood lead levels both male and female than suburban children with statistical significance(p<0.05) 3. Seventeen percent of the total subjects had lead concentrations < 5 ㎍/100㎖, and 5.88% of inner-city children and 30.23% of suburban children had this lead values. But in ≥10㎍/100㎖ group, the inner-city children(20.39%) were more distributed than suburban children(2.33%), and 12.33% of total subjects had this lead values.

      • 컴퓨터를 이용한 혈액학 교육시스템의 개발

        이기형,손보라,윤희석,조원덕,김승택 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.1

        연구목적 : 전통적인 의학교육 시스템은 최근 개발되고 있는 여러 가지 영상 진단법 등 시각적 자료를 전달하는데 한계가 있으며, 이러한 한계는 모든 분야에 걸쳐서 나타나지만 특히 혈액학이나 심장학 등 시각적인 자료가 진단에 필수적인 분양에서 두드러진다고 할 수 있다.본 연구는 혈액학 교육에 사용되던 기존의 강의실 교육에 시각적 자료가 첨부된 CD-ROM을 개발하여 혈액학 교육 시스템을 개선하기 위한 것이다. 대상 및 방법 : 기존의 혈액학 교육에 있어서 필수적으로 강의 되어오던 자료를 수집하여 체계적으로 정리하였다.강의 자료에 따라서 필요한 영상 자료를 충북대학교 병원에 입원한 혈액질환 환자들의 검사 자료로부터 수집하여 컴퓨터를 기반으로 한 의학영상 처리 및 분석시스템을 통하여 이미지 파일로 변형하였다.또한 입원 환자들 중 대표적인 증례들을 수집하여 실제 임상 진료와 유사한 형태의 증례를 통한 학습을 할 수 있도록 하였다. 결과: 본 CD-ROM은 혈액학 교육에 필요한 대부분의 영역을 포함한다 각 질환의 병태생리, 진단, 임상양상, 치료 및 예후 등 전통적으로 강의되어 오던 강의록에 이미지 파일로 변형된 영상 자료를 필요한 곳마다 링크시켰다.따라서 학습자는 특별한 장치 없이 텍스트 및 영상을 한 화면에서 볼 수 있어 전통적인 교육 시스템에 비하여 시,공간적인 장점을 갖는다 할 수 있다.또한 입원 환자들로부터 수집된 증례를 통하여 실제 임상 진료와 매우 유사한 경험을 하도록하여 교육효과를 증대시켰다. 결론: 혈액학 교육에 있어서 멀티미디어적 효과를 극대화시켜 질환의 병태생리 등 강의실 교육자료뿐 아니라 진단에 필수적인 시각적 자료를 손쉽게 접할 수 있는 CD-ROM의 개발로 전통적인 강의방법이 갖는 한계를 개선시킬 수 있을 것으로 기대된다. Purpose : The traditional medical education system has its limitations in effectiveness of conveying informations in multiple modalities used in diagnosis of patients with hematologic diseases.This study was performed to develop such a multimedia system using computer based CD-ROM, which includes visual assistant systems, several hematological case studies as well as the traditional text-wise education systems. Materials and Methods: The informations about hematologic diseases were compiled and organized.The main visual data was peripheral blood smears, bone marrow data, and several laboratory results accrued from patients admitted to Chungbuk National University Hospital.Each visual data were transformed through computer-based medical image processing and analyzing system and saved as to JPEG files.Case studies were also acquired from admitted patients and the laboratory data of that patients were used unmodified as possible as. Results : The CD-ROM covers almost all kinds of hematologic diseases that must be included in ordinary medical education courses.The text part includes pathophysiology, diagnosis, clinical features, treatment and prognosis of each hematologic diseases.The essential visual data were linked to each text part and accessible with ease, by one click.Case studies were simulated to actual clinical settings and presented step by step from diagnoses to treatments. Conclusion: A multimedia approach for the study of hematologic diseases has been developed and available in CO-ROM format.This system has advantage over traditional education system in conveying all kinds of visual data which is essential in educating hematologic disorders.

      • 延伸 Nylon6 織維의 結晶化度 및 結晶의 規則性에 關한 硏究

        李慶姬,柳德桓 慶北工業專門大學 1975 論文集 Vol.12 No.-

        The Crystallinity and the order of crystallites of nylon 6 filaments, drawn at the various draw ratios (2,3,4 & 5) and the various temperature(20,60,100 & 140℃), were studied by X-ray diffraction method. It is found that. Crystallinity is generally increased according to drawn-ratio increase, especially is remarkable at 2 drawn-ratio. Because disorder parameter, k is more appeared in case of the above of T? than the below of T?, order of crystallites shows the tendency in case of the above of T?.

      • SCOPUSSCIEKCI등재

        정상 교합자의 세가지 안면 성장유형에 따른 ODI, APDI의 변화

        이선령,박경덕,경희문,성재현 대한치과교정학회 1996 대한치과교정학회지 Vol.26 No.5

        본 연구는 안면성장유형에 있어서의 피개교합심도지수, 전후방부조화지수의 성장에 따른 변화 양상을 알아보기 위하여 정상교합자 남자 19명, 여자 14명의 10년간 격년으로 촬영한 X-선 규격사진을 Y-axis의 연구기간동안 총변화량에 따라 Drop, Neutral, Forward의 세군으로 나누어 분석하여 각 계측항목에 관하여 다음과 같은 결과를 얻었다. · 남녀 각 안면유형에서 각 연령군의 각 계측항목의 평균과 표준편차를 얻었다. · 안면유형에 따른 세 그룹간 비교에서 전후방부조화지수와 피개교합심도지수는 전 연령구간에서 유의차를 나타내지 않았다(P>0.05). 피개교합심도지수는 남녀 모두 전 연령구간에서 Drop, Neutral, Forward의 크기순으로 나타났다. · 피개교합심도지수와 전후방부조화지수는 전연구기간동안 연령증가에 따른 변화없이(P>0.05) 안정되게 유지되는 양상을 보였다. · Y-axis의 총변화량과 각 계측항목의 상관성 조사에서 A-B plane angle, Facial angle은 남녀 모두에서 상관성을 나타내었고(P>0.05) 전후방부조화지수는 여자에서만 상관성을 나타내었으나(P<0.001) 피개교합심도지수는 남녀 모두에서 상관성을 나타내지 않았다(P>0.05). The purpose of this study was to analyze the growth changes of ODI and APDI with age on the three facial growth patterns. The biennial serial cephalometric radiographs of 19 male and 14 female samples with normal occlusion during 10 years were used in this study. The samples were divided into three groups-drop type, neutral type, forward type-by the total change of the Y-axis during the periods of the study. The findings in this investigation indicated the following: 1. The mean values and standard deviations of each age group in each facial type of male and female were obtained. 2. The difference of ODI and APDI among the 3 facial types was not significant through all observed ages(P>0.05). The size of ODI appeared large consistently in order of the drop, neutral, and forward type in both male and female through all observed ages. 3. The ODI and APDI were maintained without any changes with age during the periods of the study(P>0.05). 4. In correlation analysis between the total change of the Y-axis and 6 measurements, the AB plane angle and facial angle showed correlation in both male and female(P<0.05), the APDI in only female(P<0.001), but the ODI not appeared correlation in either male or female(P>0.05).

      • 혈액형 부적합 신장이식의 현재와 과제

        이신아,강덕희 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.1

        Kidney transplantation is the best treatment for end-stage renal disease patients. However, the relative shortage of organs for transplantation has led to ABO-incompatible kidney transplantation as an accepted method to expand the pool of kidney donors. Recent advances in immunosuppression and antibody removal methods have made ABO-incompatible kidney transplantation more feasible, and have increased the opportunities for patients to receive kidney transplantation, as well as for special patients with ABO-compatible donor. Indeed, the outcome of ABO-incompatible kidney transplantation has shown remarkable developments and is now comparable to that of ABO-compatible kidney transplantation during last decade. However, there are still some uncertain issues to be addressed in ABO-incompatible kidney transplantation. In this article, we reviewed the current status and protocol of ABOincompatible kidney transplantation and listed the concerns to be addressed in near future.

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