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      • DSS의 모델베이스 내에서 모델통합에 관한 연구

        김창대,정대율 동서대학교 부설 연구소 1996 연구소 논문집 Vol.1 No.-

        Within the field of model management systems(MMS), the model integration has emerged as an important area of research. A principal objective of model integration in a model bases i to increase the porductivity of organizational modeling and decision-making activity. Recently, object-oriented concepts and technology are on the leading edge of programming language and database systems research, and their usefulness in those contexts has been successfully demonstrated. The adoption of object-oriented concept to the model integration has several benefits. Model integration problem can be classified into functional integration and definitional integration. In functional model integration, two models can be integrated by its ports. Definitional integration involves the logical linking of similar model schema. This paper showed a logical flows of model integration, and illustrated how model relationships can be detected through the concept of the object predicate. A procedure to achieve model integration is also proposed.

      • IDI형 정적연소기에서의 연락공각도가 연소특성, 및 열유속에 미치는 영향

        김시범,윤수한,이상석,하종률,전대수 東亞大學校 大學院 1998 大學院論文集 Vol.23 No.-

        We use the IDI type constant volume which is applied Indirect Injection strafied charge method to solve the problems of lean-burn such as misfire and cycle-variation. There are many factors to effect on the combustion charateristics in indirect injection strafied engine. The passagehole angle is the most important factor in that determine the direction of inflowed fuel and flame to the main chamber. In this study, we measured combustion pressure and wall temperature to examine the combustion characteristics and heat flux with the passagehole angle in the main chamber.

      • 지역 e-Learning 지원센터의 기능분석과 중요도 인식에 관한 연구

        정대율,김권수 동의대학교 경제경영전략연구소 2005 經濟經營硏究 Vol.3 No.1

        Today, many universities are confronted with the changing education paradigm such as e-Learning, Distance Education, Virtual University. This IT-based learning paradigm shift is certainly a new opportunity or a threat to our universities. To build a e-Learning system, not only many H/W and S/W resources but also expert personnels are required. An organization such as local university who is week at financial status can't himself plan the system. The Local University Community e-Learning Centers that support the demand of e-Learning requirements for their community are recommended. In order to operate these centers efficiently, the roles and functions of the center should first be defined, and the priorities of their functionalities must be rated. To define the functions of the center and assess their importance rating, we classified the function of it into four dimensions, ① contents development support, ② learning management support, ③ facilities and equipments support, ④ planning and operational management support, and each dimension has 3 or 5 measurement items. Most respondents say that contents development support factor is most important, and learning management support is next. We also tried to find the differences for each factor by the characteristics of responsor. The data showed that there was little differences between the groups in evaluating the importance of the functions of the center. Nevertheless the cross table analysis showed a significant meaning for each groups. Through the analysis, we could have recommended the operational implications for the e-Learning centers.

      • 악성 흑색종과 양성 멜라닌 세포성 모반에서 P53단백발현에 관한 면역조직화학적 연구

        이성열,이종석,김대중 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1

        This study was carried out to evaluate the aberrant expression of ?? protein using immunohistochemical method in 10 malignant melanoma and 10 melanocytic nevi. Eight out of 10(80%) and two out of 10(20%) showed positive reaction in the nucleus of malignant melanoma and benign melanocytic nevi, respectively. In conclusion, the demonstration of ?? protein in benign melanocytic nevi greatly hinders the possibility of a diagnostic use of ?? immunostaining in differentiating malignant melanoma from benign melanocytic nevi.

      • KCI등재SCOPUSSCIE

        TRIB2 Stimulates Cancer Stem-Like Properties through Activating the AKT-GSK3β-β-Catenin Signaling Axis

        Kim, Dae Kyoung,Kim, Yu Na,Kim, Ye Eun,Lee, Seo Yul,Shin, Min Joo,Do, Eun Kyoung,Choi, Kyung-Un,Kim, Seung-Chul,Kim, Ki-Hyung,Suh, Dong-Soo,Song, Parkyong,Kim, Jae Ho Korean Society for Molecular and Cellular Biology 2021 Molecules and cells Vol.44 No.7

        Tribbles homolog 2 (TRIB2) is implicated in tumorigenesis and drug resistance in various types of cancers. However, the role of TRIB2 in the regulation of tumorigenesis and drug resistance of cancer stem cells (CSCs) is still elusive. In the present study, we showed increased expression of TRIB2 in spheroid-forming and aldehyde dehydrogenase-positive CSC populations of A2780 epithelial ovarian cancer cells. Short hairpin RNA-mediated silencing of TRIB2 expression attenuates the spheroid-forming, migratory, tumorigenic, and drug-resistant properties of A2780 cells, whereas overexpression of TRIB2 increases the CSC-like characteristics. TRIB2 overexpression induced GSK3β inactivation by augmenting AKT-dependent phosphorylation of GSK3β at Ser9, followed by increasing β-catenin level via reducing the GSK3β-mediated phosphorylation of β-catenin. Treatment of TRIB2-ovexpressed A2780 cells with the phosphoinositide3-kinase inhibitor LY294002 abrogated TRIB2-stimulated proliferation, migration, drug resistance of A2780 cells. These results suggest a critical role for TRIB2 in the regulation of CSC-like properties by increasing the stability of β-catenin protein via the AKT-GSK3β-dependent pathways.

      • KCI등재

        Anatomic Study of Pterygomaxillary Junctions in Koreans

        Kim, Dong-Yul,Cho, Yeong-Cheol,Sung, Iel-Yong,Yun, Dae-Kawn,Kim, Min-Uk,Kim, Ji-Uk,Son, Hyung-Suck,Son, Jang-Ho Korean Association of Maxillofacial Plastic and Re 2013 Maxillofacial Plastic Reconstructive Surgery Vol.35 No.6

        Purpose: This study is to evaluate the location of descending palatine artery, the anatomy of pterygomaxillary junction, and the association between the obtained anatomic values and several variables. Methods: We studied 40 patients who were treated for dentofacial deformites from January 2010 to December 2012 in Ulsan University Hospital, Ulsan, Korea. Cone beam computed tomogram (CBCT) was done for all patients. The reference point was approximately 5 to 7 mm above anterior nasal spine on axial image. We evaluated the location of the greater palatine canal (line a: on the coronal view, the shortest line between the center of greater palatine canal and pterygoid fossa; distance a: the distance of line a). We also measured the thickness (line b: on the coronal view, the shortest line between maxillary posterior sinus wall and pterygoid fossa; distance b: distance of line b), width (line c: on the coronal view, the line perpendicular to the line b and the nearest line from the most concave point of lateral pterygoid plate to the medial pterygoid plate; distance c: distance of line c) and height (line d: on sagittal view, the vertically longest line of pterygoid junction; distance d: the distance of line d) in pterygomaxillary junctions. We evaluated the association between the obtained anatomic values and several variables (sex, age, height and weight). Results: The mean distance a was 4.78 mm, mean distance b was 5.53 mm, mean distance c was 8.01 mm and mean distance d was 13.22 mm. The differences between age and mean distance c and weight and mean distance d in pterygomaxillary junctions are statistically significant. Conclusion: There apparently is anatomic variation of pterygomaxillary junctions by various values, particularly weight and age in a Korean clinical population.

      • KCI등재

        Evaluation in Korean Soybean Cultivars of Resistance to Soybean Mosaic Virus

        Yul-Ho Kim,Ok-Sun Kim,Jung-Kyeong Moon,Jae-Hwan Roh,Dae-Joon Im,Il-Bong Hur,Sang-Chul Lee 韓國作物學會 2001 Korean journal of crop science Vol.46 No.1

        Soybean mosaic virus (SMV) resistance of Korean recommended soybeans was evaluated naturally and by mechanical inoculation in Suwon. Based on the differential reaction of forty-four soybean genotypes tested to nine different SMV strains, soybeans were classified into twenty-four groups. Myeongjunamulkong and Ilpumgeom-jeongkong showed a high degree of resistance to nine SMV strains, having no symptom. The other cultivars produced various reactions according to inoculation of each SMV strain: symptomless, mosaic or systemic necrosis. Only five cultivars such as Kwangankong, Eunhakong, Tawonkong, Namhaekong, Sobaegnamulkong were totally susceptible to every strain. There was variation in disease incidence. Soybeans, having the highest levels of resistance to G5H and G7H in the greenhouse, showed the lowest levels of SMV incidence in the field of Suwon. Myeong-junamulkong, Ilpumgeomjeongkong, Soyangkong, Pungsannamulkong, Sodamkong, Jangmikong, Geomjeong-kong2, Pureunkong, Sinpaldalkong2, Duyoukong, and Geumgangkong were fairly resistant to SMV. And SMV incidence of Taekwangkong, Saealkong and Baegunkong was over 45% with symptom of bud necrosis. And soybeans, highly resistant to SMV in the field and the greenhouse, were mainly derived from Jangyeobkong and Hwang-keumkong resistant to G1-G7.

      • KCI등재

        Detection of Soybean Mosaic Virus Using RT-PCR

        Kim, Yul-Ho,Kim, Ok-Sun,Lee, Bong-Choon,Roh, Jae-Hwan,Kim, Myoung-Ki,Im, Dae-Joon,Hur, Il-Bong,Lee, Sang-Chul The Korean Society of Crop Science 1999 Korean journal of crop science Vol.44 No.3

        Reverse transcription and polymerase chain reaction (RT-PCR) assay was used to detect SMV strains. A pair of oligonucleotide primers were designed to include the cylindrical inclusion (CI) coding region between 4,176 to 5,560 nt. Amplification from the total RNA extracted from infected plants with SMV yielded a 1,385 bp DNA fragment. RT-PCR was shown to be $10^3$ times more sensitive than the ELISA assay and it could detect a virus in $10^{-6}$ dilution. Restriction enzyme analysis of RT- PCR products using EcoR I showed that SMV isolates were classified into six groups according to the patterns of restriction fragments.

      • Application of Nonlinear Autoregressive with Exogenous Inputs Network to Greenhouse Environmental Modeling

        ( Dae-hyun Jung ),( Hak-jin Kim ),( Jai-eok Park ),( Sung Yul Chang ),( Taek Sung Lee ),( Joon Yong Kim ),( Hyoung Seok Kim ),( Soo Hyun Park ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Building a precise model of greenhouse inside climate is important to a response of dynamic changes and achieve an efficient climate management strategy. However, it is difficult to apply prediction models because the greenhouse climate system considers as very complex and non-linear system. Among the different nonlinear modeling methods, neural network models are gradually becoming established but few papers detail greenhouse inside climate prediction by using time series neural network models. The aim of this research is to predict the internal temperature, relative humidity, and CO<sub>2</sub> concentrations by using the external climatic data and historical data of actuators action in the greenhouse with real tomato cultivation. In order to estimate a suitability of time sequence based model, nonlinear autoregressive exogenous input network (NARX) model was built for prediction of the greenhouse inside climate conditions. For the considered greenhouse, measurements have been taken through 45 days (2/15~3/31) during winter and spring seasonal climate in Korea. The developed NARX model obtained a satisfying training accuracy with 0.91. Moreover, the prediction performance of NARX model was successfully validated with RMSE values of 0.42, 1.36, and 8.82, for temperature, humidity, and carbon dioxide concentrations, respectively.

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