消積白朮散이 Bleomycin의 副作用減少와 抗癌效果에 미치는 影響

金泰運,孫彰奎,趙鍾寬 대한한방종양학회 1999 대한한방종양학회지 Vol.5 No.1

l. Sojeokbaekchoolsan compound treatment decreased pulmonary fibrosis induced by Bleomycin. 2. At 1 and 2days after bleomycin ueament, Sojeokbaekchoolsan compund treatment decreased the number of neutrophils in bronchoalveolar lavage than those of bleomycin alone treatment. 3. SojeokMacoolsan Compound treamern increased the Fc receptor mediated rosette activity of alveolar macrophage decresed by bleomycin treatment. 4, At 1O days after bleomycin treatment,Sojeokbaekchoolsan compound treatment decreased the lipid peroxidation of tissue than those of bleomycin done treatment. 5. Anti-tumor activity of Sojeokbaekchoolsan and bleomycin compound group was higher than those of bleomycin alone treatd goto to asdic tumor caused by Sacoma-l8O tumor cells.

Plerocercoid의 표피 및 그 관련조직의 구조에 관한 연구

金鍾煥,劉寬凞,金南萬 충남대학교 자연과학연구소 1984 忠南科學硏究誌 Vol.11 No.1

The tegument of the plerocercoid stage of Spirometra sp. from Natrix tigrina was examined by electron microscopy to determine whether the most anterior level was similar to the trunk portion of the integumental structure. Significant differences were observed in the shape and arrangement of microtriches, distribution of mitochondria and the different types of bodies in the tegument. A few and short microtriches were observed at the most anterior portion, while many microtriches with long and broad proximal portion were arranged densely in the trunk portion. Many mitochondria are distributed just beneath the microtricheal layer in the anterior portion, but they were observed on the basement layer in the trunk. In the tegument of the anterior portion the most cytoplasmic bodies were showed round and oval vesicular shape, while they were rod-shape in trunk portion. The basement layer of the trunk portion was thicker than that of the anterior portion and the location of muscular layers was replaced with circular and longitudinal muscle in the anterial and trunk portion.

1994년도 法醫剖檢 통계분석

김종열,서재관 中央醫學社 1997 中央醫學 Vol.62 No.3

This is a statistical observation by authors based on the data of so called unusual death brought to this institute for medico legal autopsy by all of law enforcement agencies in Korea in the year of 1994. This report aims to reveal the facts on various causes of unusual death in Korea. The following are the summary of result:; 1. The total numbers of autopsy made for the unusual deaths were 2,123 cases, of these 1,576 cases were males and 547 cases were females. 2. Violent deaths were 1,380 cases(65.0 %), natural deaths were 657 cases(30.9 %), and unknown cases were 86(4.1 %). 3. For deaths due to injuries, blunt object injuries were the leading ahead. 4. Asphyxia deaths were 340 cases, 16.0 percents of the total and drowning were 139 cases showing the biggest number among the asphyxia] deaths. 5. Deaths from abnormal temperature and electricity were death due to fire, burning, hypothermia, heatstroke and electrocution. 6. There were 5 cases for starvation. 7. Infanticides were 8 cases, 0.4 percent of the total number. 8. For the death due to intoxication, 236 cases(11.1 %) were recorded and the biggest number among these were CO intoxication. 9. For the natural death, 657 cases, 30.9 percents of the total were recorded and the death due to the disease of the cardiovascular system was' taking the most of the total number with 323 cases. 10. Cause of death unknown due to negative autopsy and to the severe decomposition of the body were 86 cases, 4.1 percents of the total number.

인체구강상피세포의 배양조건에 대한 연구

박종수,최희웅,이수관,김수복,고광삼 中央醫學社 1990 中央醫學 Vol.55 No.2

Human epithelial cell cultures were initiated from explants of normal human oral mucosa. Growth parameter and cell type were assessed by DNA concentration and morphology of the cell lines. Tissues were excised and epithelial cells isolated by collagenase digestion. Spermine was used in order to inhibit overgrowth of the epithelial cells by fibroblast. The effects of different medium formulations were compared. Cultures maintained on the same volume of RPMI 1640 and Dulbecco's modified minimum essential medium containing 10 % fetal bovine serum, 10 ?g/ml of insulin, lng/ml of somatomedin and 10 ng/ml of epidermal growth factor showed optimal and maximal growth. For each cultured human oral epithelial cell the DNA content was in the- range of 5.7 pg to 6.6 pg. This culture system provides epithelial cells that can be used for a variety of dental and biochemical studies.

pH 변화에 따른 클로라민 생성과 분해 특성

조관형,김평청,우달식,조영태 한국환경과학회 2002 한국환경과학회지 Vol.11 No.4

본 연구의 시료는 현재 서울특별시와 수도권 도시들에서 상수원수로 이용하고 있는 한강수를 대상으로 수행되었다. 배·급수계통의 2차 소독을 위한 클로라민소독의 특성에 관하여 고찰하였으며 그 결과는 다음과 같다. 1) 25 ℃, Cl_2 / NH_3-N비 1:1 ~ 14:1에서 pH6, 7, 8의 불연속점은 각각 Cl_2 / NH_3-N비 11:1, 9:1, 10:1이었다. pH6의 경우, Cl_2 / NH_3-N비가 9:1일 때 총 잔류염소량이 최대인 반면, pH7, 8의 경우 Cl_2 / NH_3-N비가 각각 6:1, 5:1일 때 최대가 되었다. 2) pH가 6, 7, 8로 증가함에 따라 모노클로라민이 최대로 생성되는 Cl_2 / NH_3-N비는 7:1에서 5:1로 이동하였으며, pH6 ~ 8 범위에서 pH가 증가함에 따라 모노클로라민의 생성량이 많았다. 3) 클로라민의 분해는 Cl_2 / NH_3-N비가 증가하고 pH가 낮을수록 증가하였다. 클로라민의 잔류성은 유리염소보다 월등히 좋았다. pH6에서 모노클로라민과 디클로라민이 생성된 이후, 접촉시간이 경과함에 따라 디클로라민의 분포비가 증가하였다. This study was conducted to investigate the characteristics of chloramination as a secondary disinfection in a drinking water distribution system. At the range from pH 6 to pH 8, monochloramine was predominant with a trace of dichloramine, and the free chlorine was detected after breakpoint. At 25℃, the breakpoints of pH 6, 7 and 8 appeared when the weight ratios of chlorine to ammonia nitrogen were 11:1, 9:1 and 10:1 respectively, and the peak points on the breakpoint curves at pH 6, 7 and 8 were in the Cl_2 / NH_3-N ratio of 9:1, 6:1 and 5:1 respectively. As pH increased from 6 to 8, maximum point of monochloramine on the breakpoint curve was moved from 7:1 to 5:1 in the weight ratio of chlorine to ammonia nitrogen. The maximum concentration of monochloramine was formed at the pH values of 7~8 and in the Cl_2 / NH_3-N ratio below 5:1. As the Cl_2 / NH_3-N ratio increased and the pH lowered, chloramines decay proceeded at an increased rate, and residual chloramines lasted longer than the residual free chlorine. The monochloramine and the dichloramine were formed at pH 6, and then the dichloramine continued increasing with contact lime.

심리적 임파워먼트의 선행요인과 결과요인에 관한 연구

오종석,김종관,이용탁 釜山大學校 商科大學 2002 釜山商大論集 Vol.73 No.-

The purpose of this research is to examine the antecedents and outcomes of psychological empowerment. Focusing on the psychological experience of empowerment, we first examined the relationship between antecedents and the four dimensions(meaning, competence, self-determination, impact) of psychological empowerment. Second, we examined the impact of psychological empowerment on the job satisfaction and job related strain. This empirical results are as follows. First, individuals who perceive that have a high degree of self-esteem, internal of locus of control report a high level of psychological empowerment. And individuals who perceive that have a high degree of role ambiguity in their work report a lower level of psychological empowerment. Second, individuals who perceive that have a high degree of sociopolitical support, access to information, access to resources, participate work climate in their organization report a high level of psychological determinant, impact dimensions in psychological empowerment. But, competence is not significantly influence on the job satisfaction. Finally, all dimensions of psychological empowerment are not significantly impact on the job related strain. As the results, psychological empowerment is associated with in the feeling of job satisfaction, and is recognized as one means by which organizations can effectively manage management innovations.

釜山地域 經濟發展을 위한 地域企業人의 役割과 責任 : 企業家精神과 地域的 責任을 中心으로

오종석,황한식,김종관 부산대학교 1995 地域經濟硏究 Vol.- No.4

한국경제는 지금까지 국가 중심적 경제체제를 유지해 왔으나, 세계화, 지방화라는 시대적 변화에 직면하여 지역 분권적 경제체제를 확립하고, 이를 통해서 지역경쟁력을 강화함으로서 지역중심의 세계화를 추진해 나가지 않을 수 없게 되었다. 따라서 본 연구는 효과적인 지역경제발전을 모색해 나가기 위해서 부산지역을 연구대상으로 하여, 지역경제발전의 주체와 지역경제발전의 원동력을 조명하고, 지역경제발전을 위해서는 어떠한 환경이 조성되어야 하는 지를 문헌연구와 실증연구를 토대로 하여 고찰해 보고자 하였다. 그 결과, 다음과 같은 결론을 도출할 수 있었다. 첫째, 세계화, 지방화 시대의 지역경제 발전전략은 자립적·내발적 이어야 하며, 지역 스스로가 발전주체가 되어야 한다는 점이다. 특히 지역기업인은 지역에서 가장 중심적인 역할을 담담해야 하며, 지역기업 중심의 지역주체성 확립이 지역경제 발전의 기반이 되어야 한다는 것이다. 둘째, 지역경제 발전의 원동력은 지역기업인의 기업가정신과 지역적 책임이며, 이것을 통해 기업의 내생력을 강화시켜서 기업발전을 이룩하고, 지역경제의 발전을 실현해 나가야 한다는 점이다. 셋째, 지역경제의 발전을 위해서는 지역경제의 낙후원인을 분석, 진단하고 이를 통해서 외생적 환경조건을 정비함으로써 지역경제의 발전을 도모해 나가야 한다는 것이다.

1994년도 法醫剖檢 통계분석

서재관,김종열 大韓法醫學會 1995 대한법의학회지 Vol.19 No.2

This is a statistical observation by authors based on the data of so called unusual death brought to this institute for medicolegal autopsy by all of law enforcement agencies in Korea in the year of 1994. This report aims to reveal the facts on various causes of unusual death in Korea. The following are the summary of results, 1. The total numbers of autopsy made for the unusual deaths were 2,123 cases, of these 1,576 cases were males and 547 cases were females. 2. Violent deaths were 1,380 cases (65.0%), natural deaths were 657 cases (30.9%), and unknown cases were 86(4.1%). 3. For deaths due to injuries, blunt object injuries were the leading ahead. 4. Asphyxial deaths were 340 cases, 16.0 percents of the total and drowning were 139 cases showing the biggest number among the asphyxial deaths. 5. Deaths from abnormal temperature and electricity were death due to fire, burning, hypothermia, heatstroke and electrocution. 6. There were 5 cases for starvation 7. Infanticides were 8 cases, 0.4 percent of the total number. 8. For the death due to intoxication, 236 cases (11.1%) were recorded and the biggest number among these was CO intoxication. 9. For the natural death, 657 cases, 30.9 percents of the total were recorded and the death due to the disease of the cardiovascular system was taking the most of the total number with 323 cases. 10. Cause of death unknown due to negative autopsy and to the severe decomposition of the body were 86 cases, 4.1 percents of the total number

비안와대뇌형 모균증 치험 3례

문영일,김종남,홍순관,이지애,정옥경,김문정 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.3

Rhinocerebral mucormycosis is a well-described fulminant fungal infection that typically presents in a rapidly fulminant manner. This condition is more likely to occur among patient with diabetes mellitus, malignant tumors, who have long-term steroid treatment, or who suffer from some debilitating diseases. We report 3 cases of rhinoorbitocerebral mucormycosis, all suffered from diabetes mellitus. In all 3 cases, endoscopic sinus surgery was done and the antifungal agent(amphotericin B) was administered intravenously, and two patients died. One survivor who had focal extension of paranasal sinus and orbit, required one surgical intervention without orbital exenteration and he is alive without recurrence disease. The severity of the disease is probably dependent upon the gost resistance to the invasion of phycomycetes. Early diagnosis and immediate, effective treatment are the key for cure of the disease.

유구치 와동형성이 아말감 파절에 미치는 영향에 관한 연구

하대송,김종관,이종갑 大韓小兒齒科學會 1984 大韓小兒齒科學會誌 Vol.11 No.1

In this experiments, the fracture loads were measured and analysed by using of Instron universal testing machine (Model 1132). With 80 upper and lower deciduous molars that were free of dental caries. Isthmus of teeth were prepared to 1/3 and 1/4 of intercuspal width, and internal line angles with round and sharp shape, and then amalgam restoration were performed. The results of this study were as follows; 1. Resistance to fracture loads were greater with isthmus of 1/3 intercuspal width than of 1/4 intercuspal width, especially, statistically significant difference on upper and lower second deciduous molars. 2. Resistance to fracture loads were greater with rounded internal line angle than sharp internal line angle. The above results were as follows, the fracture loads had greater resistance on isthmus of 1/3 intercuspal width, and rounded internal line angle, but normal physiological occlusal forces could permit isthmus of 1/4 intercuspal width and rounded internal line angle.