A Case of Cold Medicine-Induced Hepatitis Treated with Herbal Medicine

손창규 대한한의학회 2011 대한한의학회지 Vol.32 No.6

Objectives: To inform the clinical features of drug-induced liver injury (DILI), and study traditional Korean medicine (TKM)-based strategies or therapeutics. Methods: A female patient with hepatitis after long term use of medication for cold symptoms was treated with Oriental therapies, after which the clinical outcome was evaluated by serum biochemical parameters and ultrasonography. Results: Clinical and biochemical levels were fluctuating during administration of cold medicine, but the patient completely recovered her health with herbal medicines. Conclusion: This case report would provide information about a typical DILI by western medicine followed by treatment with traditional Korean medicine.

A Clinical Report of Adult Acute Viral Hepatitis Type A Treated with Herbal Prescriptions

손창규 대한한의학회 2007 대한한의학회지 Vol.28 No.4

Owing to improvement of socioeconomic status during recent decades in Korea, incidence of hepatitis A has rapidly decreased, especially among children. However, this status has paradoxically caused a steady increase of adult patients with HAV infection, causing new medical issues associated with aggravated clinical symptoms. The present study reports an adult case of acute viral hepatitis type A treated with oriental medicine. The elevated biochemical findings(AST, ALT, gamma-GTP, bilirubin), physical symptoms (general weakness, nausea, right flank pain, itching sign), and serological makers (anti-HAV IgM and anti-HAV IgG) were normalized within four weeks. Also, sonographic examination showed a normal pattern on an enlarged liver image. This study informed us about the clinical capacity of oriental medicine for adult patients with acute viral hepatitis type A.

암(癌) 치료(治療)에 있어서 부정거사법(扶正祛邪法)의 운용(運用)에 관(關)한 고찰(考察)

손창규,조종관,Son, Chang-Gyu,Jo, Jong-Gwan 대한한방내과학회 1995 大韓韓方內科學會誌 Vol.16 No.2

Observation of Complete Blood Count and Biochemical Parameter after Indirect Moxibustion (CV4, CV8) in Healthy Adults

손창규 경락경혈학회 2010 Korean Journal of Acupuncture Vol.27 No.1

본 연구는 간접구의 안전성에 대한 기초 데이터를 확보하기 위하여 수행되었다. 연구설계 : 50명의 건강한 성인을 무작위 배정으로 두 그룹으로 나누어 4주간 (일주일에 3회) 신궐혈과 관원혈에 뜸을 시술하였다. 시험군에 비하여 대조군은 열이 전달되지 않도록 단열제로 처리한 뜸으로 동일한 부위에 시술하였다. 첫 시술 1시간 전과 마지막 시술 1시간 후에 공복상태에서 채혈을 하여 혈액학적 검사를 시행하였다. 결과 : 혈액학적 검사에서 적혈구와 총 백혈구 및 백혈구의 종류별 절대수치와 상대수치에서 두 그룹 간에 특별한 차이가 없었다. 또한 혈청학적 검사에서 총 단백질, 알부민, AST, ALT, ALP, GGT, LDH, 요소질소, 크레아티닌, 총콜레스테롤 및 중성지방의 비교에서도 그룹 간에 차이가 없었다. 결론 : 본 연구는 건강한 사람에서 간접구의 시행 후 혈액학적 안전성을 처음으로 보고하는 것으로서, 향후 뜸의 연구를 수행시 중요한 비교 자료로 사용될 수 있을 것이다.

Demand Survey for Application of Environmental Therapy for Atopic Dermatitis

손창규 대한한의학회 2014 대한한의학회지 Vol.35 No.2

Objective: This study aimed to investigate the demand for natural environment therapy among parents of patients with atopic dermatitis. Methods: The questionnaire-based survey was conducted on the parents of 310 patients with atopic dermatitis (158 male and 152 female, median age 8 years, ranging from 2 to 21 years). The questionnaire consisted of 10 questions including demographic information, preference of environmental therapy and related choices. Results: Regardless of illness severity or gender, parents agreed with the importance of environmental therapy in treatment for atopic dermatitis. 55.2% of parents had considered moving to the countryside for their children with atopic dermatitis. 74.5% of parents answered positively to the possibility of movement to an atopy-free village, and this rate was significantly higher in parents of patients with severe symptoms (p < 0.05). Educational facilities and eco-environment were considered to be the most important factors in their decision. In addition, parents opted for organic food cooperatives, which was also felt necessary for their children suffering from atopic dermatitis. Conclusions: This study is the first report suggesting the extent of demand for environmental therapies among patients with atopic dermatitis. This information will be helpful in developing therapeutics using the natural environment in Korean medicine.

Ralston의 Crossvergence 이론 검증을 위한 추가연구: 2007년과 2017년 한국 미국 TV광고에 투영된 문화적 가치 중심으로

손창규,윤각 한국광고학회 2020 광고학연구 Vol.31 No.6

Ralston(2008) claimed that the socio-cultural dimensions of a country’s cultural values tend to remain unchanged over time (divergence) while the business ideology dimensions can change in a short period of time (convergence). This study has been executed to supplement the limitations of the precedent study which examined the plausibility of this ‘crossvergence’ theory. We conducted a content analysis by comparing the cultural values reflected in Korean and US TV ads from 2007 and 2017, using a coding scheme consisting of 8 socio-cultural and 5 business ideology dimensions on a total of 400 samples. In addition, this study examined the advertising executional elements in the ads of the two countries. All the 8 socio-cultural dimensions of both countries except only one (the collectivism of Korea) showed no significant changes in the ten year period, supporting ‘divergence’. The fact that 5 business ideologies of both countries, however, has increased in ten years but showed no decrease in difference between both countries in ten years was not entirely consistent with the ‘convergence’. These mixed findings call for a close examination of Ralston’s ‘crossvergence’ argument. None of the dimensions and sub-dimensions in terms of the ad executional elements showed significant changes in both countries between 2007 and 2017, thus supporting ‘divergence’ because ad executional elements also reflect the nature of socio-cultural dimensions. Finally, the Korean ads showed a significantly higher use of rational appeals, which are typical characteristics of low-context culture value, and the US ads employed a higher use of emotional appeal, which are those of high-context culture value. We believe this finding let us acknowledge that it is not always for ad to reflect its culture background and that ad occasionally reflects other influences such as the characteristics of client and media. Theoretical and practical implications of the findings are offered. Ralston(2008)은 한 국가나 사회의 사회문화적 가치는 시간이 흘러도 변하기 쉽지않는 반면(divergence), 비즈니스 이데올로기 가치는 비교적 짧은 시간에도변할 수 있다(convergence)는 크로스버전스(crossvergence) 이론을 주장했다. 이러한 크로스버전스 이론을 광고차원에서 검증하고자 선행연구(2019)가 진행되었고, 해당 연구의 한계점을 보완하기 위해서 본 연구는 추가로 실시되었다. 문화적 가치가 다른 한국과 미국을 대상으로 2007 년도와 2017년도 TV광고를 분석한 본 연구는 8개의 사회문화적 가치 차원들과 5개의 비즈니스이데올로기 관련 가치 차원들로 구성된 유목을 활용해 총 400개의 샘플에 대한 내용분석을 실행했다. 또한 본 연구는 양국의 광고 실행 요소들에 대한 비교분석을 실시했다. 분석 결과, 한국과 미국의 8개의 사회문화적 가치 차원들 중 오직 한 개(한국의 집단주의)를 제외한 나머지 가치들이 10년 사이에 유의미한 변화를 보이지 않아 비수렴(divergence) 이론을 지지한 것으로 나타났다. 반면에 5개의 비즈니스 이데올로기 차원의 가치들을 분석한 결과 10년사이에 양국에서 공히 비즈니스 이데올로기 가치들이 증가하였지만, 07년 대비 17년에 보다 유사해진 결과를 나타내지 않아 수렴(convergence)이론을 부분 지지하는 것으로 나타나 결과적으로 크로스버전스를 부분 지지하는 결과를 얻었다. 한편 대유목인 광고 실행요인을 분석한 결과, 07년과 17년 모두 한국과 미국 공히 광고실행요인은 유의미한 차이가 없었고, 중유목 차원에서도 유의미한 차이가 발견되지 않았다. 광고실행요인 또한 사회문화적 가치를 반영한다는 점에서이 또한 비수렴이 지지되는 방증이라 하겠다. 광고실행요인 차원에서 예상과는 달리, 한국은 저맥락 문화의 광고 특성 중 하나인 이성소구를 많이 사용하고 미국은 고맥락 문화 특성인 감성소구를 많이 사용하는 것으로 나타났다. 이를 통해 광고가 항상 문화가치를 반영한다는 생각은위험하며, 문화가치 이외에도 광고주 특성, 매체 특성 등 다양한 요인이 작용할 수 있다고 판단된다. 그리고 연구의 의의 및 한계와 후속연구에 대한 제언 등이 제시되었다.

Systemic Review of RCTs focusing on Chronic Fatigue

손창규 대한한의학회 2009 대한한의학회지 Vol.30 No.6

Objective:This study aimed to build an overview of randomized clinical controlled trials (RCTs) for chronic fatigue-related symptoms to extract the useful data for management of patients and development of therapeutics using Korean traditional medicine in the future. Methods:All RCT-derived papers for chronic fatigue-related symptoms were collected via PubMed Database. We surveyed elementary information of RCTs such as clinical question, study design, and its quality and results. Results:A total of fifty-three RCTs met these review criteria. Most of the RCTs were performed in Western countries, particularly the UK and USA. The major portion of RCTs focused on chronic fatigue syndrome using immune modulators, psychotherapeutic and anti-depressants. Five RCTs using complementary and alternative medicine, including herbal remedies, showed positive results. Conclusions:Fatigue-related symptoms are a main target of Oriental medicine. This study provides helpful information for planning clinical study of chronic fatigue-related symptoms using traditional Korean medicine. Objective:This study aimed to build an overview of randomized clinical controlled trials (RCTs) for chronic fatigue-related symptoms to extract the useful data for management of patients and development of therapeutics using Korean traditional medicine in the future. Methods:All RCT-derived papers for chronic fatigue-related symptoms were collected via PubMed Database. We surveyed elementary information of RCTs such as clinical question, study design, and its quality and results. Results:A total of fifty-three RCTs met these review criteria. Most of the RCTs were performed in Western countries, particularly the UK and USA. The major portion of RCTs focused on chronic fatigue syndrome using immune modulators, psychotherapeutic and anti-depressants. Five RCTs using complementary and alternative medicine, including herbal remedies, showed positive results. Conclusions:Fatigue-related symptoms are a main target of Oriental medicine. This study provides helpful information for planning clinical study of chronic fatigue-related symptoms using traditional Korean medicine.

Homogeneously Dispersed Silver Nanoparticles in EVA Laminating Film for Efficiency Enhancement of Silicon Photovoltaic Cells

손창규,강홍석,김진우,이홍경,안성호,박정기,김희탁 한국고분자학회 2016 Macromolecular Research Vol.24 No.5

We present a simple yet high-throughput approach for placing homogeneously dispersed silver nanoparticles (AgNPs) onto the top surface of a photovoltaic cell which can improve power conversion efficiency of a photovoltaic cell. Our system is realized in two major steps: i) fabricating a AgNP-dispersed ethylene-vinyl acetate copolymer (EVA) thin film from a AgNP/EVA mixture and ii) subsequently laminating the top surface of the photovoltaic cell by using the film. To achieve good dispersion of the AgNPs, a maleic anhydride-grafted polypropylene (PP-g-MAH) is added to the AgNP/EVA mixtures as a compatibilizer. Owing to the good AgNPs dispersion, the obtained thin film shows an extremely high light scattering, thus enhancing the power conversion efficiency of the resulting photovoltaic cell.

백미발효 화장품(Whitecrow)의 임상적 미백효과 평가

손창규,장은수,이삼근,방기정 한국패션비즈니스학회 2020 패션 비즈니스 Vol.24 No.2

This study evaluated the Skin Whitening effects of ‘fermented-C.’ for Atrium cosmetics using a single-arm clinical trial. Twenty female adults (mean age 42.1 ± 6.6 year) were enrolled, all participants used this cosmetic product on their face for 4 weeks. The change of brightness (L-value) was measured by spectrophotometer while subjective assessments were also obtained to find the participants opinions on whitening and their general satisfaction measured by a 5-point scale (5 for very satisfactory, 5 for satisfactory, 3 for moderate, 2 for unsatisfactory, 1 for very unsatisfactory). The participants were also questioned about any adverse effects by filling out a self-monitoring report. The average L-value increased from 62.55 ± 2.14 on day 0 to 63.22 ± 1.96 after 4 weeks corresponding to a 1.1% brightness improvement (p < 0.01). The average scores for subjective whitening and general satisfaction were better than moderate with scores of 3.6 ± 0.5 and 3.7 ± 0.7, respectively. No notable complaints were reported regarding any kind of adverse effects such as erythema, itching or burning. The clinical data collected in this study supports that fermented-C. from Atrium cosmetics has whitening potential in a safe Functional Cosmetics package.

智異山 國立公園의 利用實態에 關한 硏究

孫昌奎 전남대학교 한국농어촌개발연구소 1973 농산어촌개발연구 Vol.7 No.-

The study on the recreations in the Hwaom Temple ground, of the Mt. Chiri National Park treats with Some tourist’ s response to the district and t1íe movement of the travellers • devoting on the development plan of the 'park and recreatloo ground. The results are summarized as follows: 1. Most visitors are from Chonnam and Chonbuk Province which accounts for 58.5%. and on the otherhand from the city of Seoul and Busan only 19~4% of the total. 2. The favorite season for travelling is autumn for 51. 7% . of the 'respondents. but actually most travellers were: in spring time. It.is the one reason that the season have two big festival days, that is Yagsu-Je and Buddha's birthday. 3. Intoxicating with the beauty of nature, sight seeing, emancipation from worldly concern, and promoting friendship are their most motivations of visiting this ground (47.7%). 4. Due to the uneven surface of the road, poor means of tranportation. along the lack of recreation facilities , 53.8% of the tourist complained that travelling was unleasant. and do not want to vist more. 5. 25% of the travellers complained of the inelegance of treeIess mountain along the entrance to the Hwaom Temple grounds, but after they reach there, they count the beautiful scenery and the stillness of the woods are instilling( 44.2%). 6. The most urgent service for this grounds are said as follows: 1) public latrine (23.6%) 2) recreation facilities (14.7%) 3) public telephone (13.7%) 4) portable water supply system (13. 1%) At present time, above facilities are lacking io. 7. They want such a indigenous trees for the road-side as the cherry tree( 42.5%), gingko tree(18.29-ó), ze]kova tree(12.6%) and camelJia(lO.8%). 8. During the seventy five days of the survey term, total of 23.700 persons visit this grounds and on the average 274.4 persons a day. on the date of ApriI 2O, 1973-the day has the festival Yagsu-Je when it was at its. peak. the park recorded 14.536 persons. A conclusion can be drawn that about 150.000 people are estimated to have visited. this scenic place in 1972 by taking 274 persons a day 00 the average and plus about 50, 000 persons in the two festvals, that is Yagsu-Je and Buddha’s birth day.