후두결핵의 임상양상과 진단

조현진,소윤경,손영익,Cho, Hyun-Jin,So, Yoon-Kyoung,Son, Young-Ik 대한후두음성언어의학회 2008 대한후두음성언어의학회지 Vol.19 No.1

Background and Objectives : Clinical suspicion and appropriate diagnostic procedures are essential for the timely management of extrapulmonary type of mycobacterial disease. In the hope of suggesting a suitable guideline for the early diagnosis of laryngeal tuberculosis, the authors reviewed their clinical pathways and the characteristics of patients with laryngeal tuberculosis who were managed in the recent 10 years at a single tertiary referral hospital, Samsung Medical Center. Subjects and Method : Retrospective chart review was performed for the 25 adult patients with laryngeal tuberculosis. Among 25 cases, 12 were pathologically confirmed by laryngeal biopsy and the other 13 were clinically diagnosed by cumulative clinical information; definite laryngitis on laryngoscopy, positive AFB (acid fast bacillus) smear/culture or active pulmonary tuberculosis on chest X-ray, and substantial response to anti-tuberculosis medication. Results : Chest X-ray revealed active pulmonary tuberculosis in 72% of patients (N=18/25). Sputum AFB smear/culture was positive in 95% of all tested patients (N=21/22) and in 100% of the tested patients who have stable or no evidence of pulmonary tuberculosis (N=5/5). All patients except one who had coexisting laryngeal malignancy showed considerable improvement in their subjective symptoms and laryngeal findings within the first 2 months of anti-tuberculosis medications and they achieved complete response on subsequent sputum studies, chest X-ray and laryngeal findings after $7.0{\pm}2.3$ months of the medications. Conclusion : We suggest that chest X-ray and sputum AFB smear/culture to be the first step of work-up for the patients having laryngeal tuberculosis in suspicion since laryngeal tuberculosis is largely associated with active pulmonary tuberculosis and/or sputum AFB study offers high yield even in case of primary laryngeal tuberculosis. However laryngeal biopsy must be considered in case showing unsatisfactory response to the anti-tuberculosis medication for more than 2 months.

소아약증직결(小兒藥證直訣)에 기재(記載)된 방제(方劑)의 특성분석(特性分析)

조현진,박선동,Cho, Hyun-Jin,Park, Sun-Dong 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1

Objectives : This study aims to reveal the characteristics of formulas in "Xi$\v{a}$o' Er Y$\`{a}$o Zh$\`{e}$ng Zh$\'{\i}$ Ju$\'{\e}$. Methods : For that objectives, We analyzes formulas in "Xi$\v{a}$o' Er Y$\`{a}$o Zh$\`{e}$ng Zh$\'{\i}$ Ju$\'{\e}$. In the text, 132 formulas were described. To comprehend the formulas, we classified them as several bases. Results : After those analyses, we bring to a conclusion as follows. 1. 30 formulas are described that treated convulsive diseases (j$\={i}$ngf$\={e}$ng, ?風). Next, g$\={a}$n(疳), parasite infection, diarrhea/dysentery, dermatosis and etc were in the order. 2. Classified by the formulation, Yu$\'{\a}$nj$\`{i}$(圓劑) was the best(70 kinds of formulas, 53%). S$\v{a}$nj$\`{i}$(散劑) was a form of 41 formulas(31%). T$\={a}$ngj$\`{i}$(湯劑) and g$\={a}$oj$\`{i}$(膏劑) were a form of 5 formulas each. 10 formulas were assumed the form of w$\`{a}$iy$\`{o}$ngj$\`{i}$(外用劑). 3. We researched in-depth analysis of Yu$\'{\a}$nj$\`{i}$. As a results, dosage, additive(輔料) and the time to take of Yu$\'{\a}$nj$\`{i}$ were decomposed. Also, the formulas that treated convulsive diseases were analyzed by the herbs classification. Conclusions : Though the formulas that treated convulsive diseases were hard to application at local clinic, overall nosology of pediatrics was reflected comparatively. "Xi$\v{a}$o' Er Y$\`{a}$o Zh$\`{e}$ng Zh$\'{\i}$ Ju$\'{\e}$ was expected to play a role for reconsideration of formulas' formulation.

미국 멕시코만 기름유출사고에서 본 유처리제 사용의 효용성 고찰

조현진,하창우,Cho, Hyun-Jin,Ha, Chang-Woo The Korean Society of Marine Environment and safet 2012 해양환경안전학회지 Vol.18 No.1

바다에 기름오염 사고가 발생하면 여러 가지 방제 방법 중 물리적 회수 방법을 우선적으로 사용하고 유처리제는 최후 수단으로 고려하는 경향이 있다. 유처리제는 수중으로 기름이 신속히 분산되도록 하여 해수면으로부터 제거하는 방법이다. 해수면으로부터 신속히 기름을 제거하는데 대한 유처리제의 효용성은 널리 증명되어 왔으나 아직도 대부분의 국가들은 해양환경에 미치는 독성을 우려하여 적극적인 사용을 하지 않고 있는 실정이다. 보고된 자료에 의하면 유처리제와 혼합된 기름이 기름 그 자체보다 독성이 더 크게 나타나지 않았다. 멕시코만 기름유출 사고시 미국 정부와 BP사는 최대한 해안에 기름이 도달하지 않는데 중점을 두고 해수면뿐만 아니라 수중의 기름에 대해서도 유처리제를 사용하였다. 유처리제에 대한 순환경편익을 분석하면 유처리제를 사용함으로써 기름이 생태계에 머무는 시간이 줄어들며 장기간 노출을 예방하고 야생동물에 심각한 오염을 방지하는 효과가 있는 등 다양한 연구가 진행되고 있다. 미국 멕시코만 유류오염 사고와 같은 대규모 해양오염사고의 위험이 상존하는 우리 실정에서도 과학적 결과를 바탕으로 한 유처리제 사용의 효용성과 안전성에 대한 검토가 이루어져야 할 시점이라 사료된다. Once oil has spilled, oil spill responders use a variety of countermeasures to reduce the adverse effects of spilled oil on the environment. Mechanical methods of containment and recovery are preferred as the first response when the use of other methods fail or are ineffective. In these cases, the application of oil dispersants shall be use only as a last resort. While effectiveness of dispersants in removing oil form the sea surface is proven, the use of dispersants is controlled in almost all countries due to the toxicity of their active agents and the dispersed oil on the marine environment. However, according to reports, after dispersant application, no significant toxicity to fish or shrimp was observed in the field-collected samples. Moreover, the results also indicate that dispersant-oil mixtures are generally no more toxic to the aquatic test species than oil alone. During the Deepwater Horizon Incident, dispersants were applied to floating oil and injected into the oil plume at depth. These decisions were carefully considered by state and federal agencies, as well as BP, to prevent as much oil as possible from reaching sensitive shoreline habitats. Net Environmental Benefit Analysis for dispersant use assumed that dispersants appear to prevent long-term contamination resulting absence of oil in the substrate and will benefit marine wildlife by decreasing the risk of significant contamination to feathers or fur. Further study to use dispersants with scientific baseline is needed for our maritime environment which consistently threaten huge oil spill incidents occurrence.

Response Activities for Tar Ball Pollution from the 'Hebei Spirit' Oil Spill in the Southwestern Sea of Korea

조현진,김정엽,양문철,서광열,민남기,임승혁,전성근,김희식,김영화,김지훈,장선희,Cho, Hyun-Jin,Kim, Jeong-Yeop,Yang, Mun-Chul,Seo, Kang-Ryul,Min, Nam-Gi,Im, Sung-Huk,Jeon, Sung-Gun,Kim, Hee-Sik,Kim, Young-Hwa,Kim, Gi-Hun,Chang, Sun-Hee The Korean Society for Marine Environment and Ener 2009 한국해양환경·에너지학회지 Vol.16 No.4

2007년 12월 7일 발생한 허베이스피리트호 원유유출 사고로 약 12,547 kL의 기름이 해상으로 유출되어 서해안의 해안선이 광범위하게 기름으로 뒤덮이는 결과가 초래되었다. 사고발생 며칠 후부터 타르볼이 서남해안에서 관측되었으며, 이에 대한 방제를 위해 해양경찰(KCG)은 해상에서는 뜰채 및 그물끌기 방법을 이용하였고, 해안에서는 그물치기, 주워내기, 쓸어 담기 등 3가지 방제방법을 이용하였다. 그물막 치기 방법은 해안이 타르볼로 오염되는 것을 예방하는데 효과적이었으며, 사고당시의 계절이 겨울이었던 점은 타르볼이 쉽게 굳어 자원봉사자나 주민들이 주워 내거나 쓸어 담는데 큰 이점이 될 수 있었다. Approximately 12,547 kL of oil from the tanker 'Hebei Spirit' released into the western sea of Korea, which subsequently reached and covered extensive areas of the western coastlines of Korea. In the following days great numbers of tar balls hit the southwestern coast. Three different cleanup methods were used to mediate the southwestern coastline tar ball pollution by Korea Coast Guard (KCG) net setting, manual pick up, and sweeping them up. Net setting was useful in protecting coastlines from being hit by tar balls. The cold weather in winter conditions helped the tar ball response efforts because it caused them to harden, allowing them to be swept up from beaches and to be gathered up by hand.

소아약증직결(小兒藥證直訣)의 처방분석(處方分析)

조현진,박기정,박선동,Cho, Hyun-Jin,Park, Ki-Jeong,Park, Sun-Dong 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.2

Objectives : This study aimed to reveal the characteristics of formulas in "Key to Therapeutics of Children's Diseases" by analysis of crude drugs that constitute formulas. Methods : To analyze the formulas, We classified the formulas to presenting symptom classification. And within that categories, the crude drugs in formulas were diagrammatized. Results : After those analyses, we brought a conclusion as like these. 1. The formulas classified into some categories that include chronic consumption disease, parasitization, digestive system disease, febricity, infectious disease, respiratory disease, skin disease, infirmity and etc. 2. We analyzed the characteristic of formulas by categorization of crude drug combination. In this way, we recognized that Qian Yi(錢乙) frequently used cold crude drugs unlike the trend of S$\grave{o}$ng(宋) dynasty doctors. 3. The prescription that described in "Key to Therapeutics of Children's Diseases" can be found in "Treasured Mirror of Eastern Medicine(東醫寶鑑)" and the other books on posterity. Conclusions : Through these researches, we verified that Qian Yi affect cold herbal and mineral drugs. This tendency of Qian Yi have an effect on the Nourish yin school. And several decades of formulas of "Key to Therapeutics of Children's Diseases" contain in part of pediatrics on "Treasured Mirror of Eastern Medicine". We reconfirmed that Qian Yi affected profound influence on the development of pediatrics and Nourish yin school.

보론 나이트라이드 나노튜브 합성 및 응용기술

조현진,김준희,김명종,Cho, Hyun Jin,Kim, Jun Hee,Kim, Myung Jong 한국진공학회 2016 진공 이야기 Vol.3 No.3

BNNTs (Boron nitride nanotubes) is an analogue of CNTs (Carbon Nanotubes) in terms of lattice structure. In BNNTs, a boron atom forms sp2 hybridized bonding with three nitrogen atoms, and so does a nitrogen with three boron atoms in the honeycomb structure. Its innovative properties, such as high thermal conductivity, neutron shielding capability, superb oxidation resistance at $900^{\circ}C$, excellent chemical resistance, and superior mechanical properties are advantageous for a wide range of applications, especially for electric device packages, neutron shielding, protective coating materials, and functional composites. In this paper, boron nitride nanotube synthesis, properties and application are reviewed.

정현파 신호 주파수 추정 알고리즘의 추정 정확도 비교 연구

조현진,Cho, Hyunjin 한국음향학회 2018 韓國音響學會誌 Vol.37 No.6

본 논문은 정현파 신호에 대해 고해상도 주파수 추정이 가능한 알고리즘들의 성능을 비교 분석하였다. 비교 대상 알고리즘은 총 5가지로 DFT(Discrete Fourier Transform - 성능 평가 기준), Jacobsen, Candan, 재할당(Reassignment) 알고리즘 및 Cedron 알고리즘이다. 각 알고리즘의 성능을 SNR(Signal to Noise Ratio), 윈도우 함수, 윈도우 길이 등의 요소를 변화시켜가며 성능을 측정하였다. 알고리즘의 성능 평가는 편의 및 오차(Mean Square Error, MSE), 분산을 이용하여 측정하였으며, 실험결과 Cedron 알고리즘이 좋은 성능을 보였다. 실제 공학문제에서의 활용을 위해서는 각 알고리즘별로 보다 다양한 조건에서 실험 결과를 분석하고 개선시킬 필요가 있다. This paper presents performance comparison of several high-resolution frequency estimation algorithms for pure real tone signal. Algorithms are DFT (Discrete Fourier Transform - for reference purpose), Jacobsen, Candan, reassignment and Cedron. Each algorithm is evaluated under various experimental conditions, e.g., different SNR (Signal to Noise Ratio), window function and window length and performance is compared in the perspective of bias, MSE (Mean Square-Error) and variance. Experimental results indicate that Cedron algorithms works well in the most cases. For actual usage in the engineering problem, each algorithm needs additional analysis and modification.

마찰교반 점용접(FSJ)을 이용한 Mg 합금의 접합성 평가

조현진,김흥주,천창근,장웅성,Cho, Hyeon-Jin,Kim, Heung-Ju,Cheon, Chang-Keun,Chang, Woong-Seong 대한용접접합학회 2006 대한용접·접합학회지 Vol.24 No.4

선유도어뢰 전술 효과도 분석을 위한 교전수준 모델 개발 연구

조현진,Cho, Hyunjin 한국시뮬레이션학회 2018 한국시뮬레이션학회 논문지 Vol.27 No.1

본 연구에서는 선유도 중어뢰의 전술 효과도 예측을 위하여 개발한 교전수준 시뮬레이터에 대해서 시뮬레이터 개발에 적용된 개념 및 구성요소 모델에 대해서 소개하고 있다. 특히 어뢰의 공격문제 해결을 위하여 기하학적 모델에 따른 해(Closed-form solution)를 도출하였고, 어뢰의 공격유도 방법에 비례항법 유도를 적용하여 구현하였다. 표적함에 대해서는 속도와 소음의 상충관계로 인한 피탐 가능성을 고려하였다. 어뢰의 초기위치에 따른 공격 소요 시간을 계산하고 이를 도시화하는 과정을 통하여 도출된 해의 정확성을 확인 할 수 있었고, 현실적인 공격유도 방법 및 소음원 모사를 통하여 시뮬레이터 충실도를 높일 수 있었다. 시뮬레이터는 다양한 전술상황을 가정하여 결과를 분석 할 수 있도록 자유도가 높게 개발되었으며, 구성요소 궤적 분석 및 전방위 요격 성공률 분석이 가능하여 전장 상황의 흐름을 파악하고 전술에 대한 이해를 높이는데 도움이 된다. This paper introduces the simulation concepts and technical approach of wire-guided torpedo performance analysis simulator, as a consequence, provide a framework for understanding overall attack procedures and effectiveness of tactics to torpedo operator. It described the mathematical models of simulation components and weapon engagement principle, especially it derived the closed-form solution of time consumption and leading angle problem of torpedo attack situation based on geographical assumption. In addition, it adopted the proportional navigation guidance at final stage of torpedo attack and also consider the tradeoff relation between target ship speed(propeller noise level) and detection probability, so that it improves the fidelity of physical realism. Simulator is developed with high degree of freedom in the perspective of tactical situation, and it helps user to understand the overall situation and tactical effectiveness.

Neyman-Pearson 표적 탐지기를 적용한 수중 무기체계 교전수준 모델 개발 연구

조현진,김완진,김상훈,양호철,이희광,Cho, Hyunjin,Kim, Wan-Jin,Kim, Sanghun,Yang, Hocheol,Lee, Hee Kwang 한국시뮬레이션학회 2019 한국시뮬레이션학회 논문지 Vol.28 No.2

본 연구에서는 수중 무기체계의 효과도 예측을 위하여 개발한 교전 수준 시뮬레이터에 대해서 표적탐지 여부의 확률적 접근 방법을 적용한 개념 및 그 예시를 소개하고 있다. 소나 방정식에 의해서 산출되는 SE(Signal excess)을 이용하여 표적의 존재 여부($H_0$ 혹은 $H_1$)에 따른 확률 분포 함수(PDF, Probability density function)을 유도하였다. 이후 Neyman-Pearson 탐지기에 따라 $P_{FA}$(Probability of false alarm)을 만족하는 $P_D$(Probablity of detection)을 구하고 탐지 여부를 확률적으로 판단하도록 설계하였다. 표적의 탐지와 관련된 현실적인 접근방법을 도입함으로써 시뮬레이터의 충실도를 높일 수 있었으며, 실험 결과는 전술 구상의 보조 정보로 활용할 수 있을 것이라 예상한다. This paper introduces the simulation concepts and technical approach of underwater weapon system performance analysis simulator, especially focused on probabilistic target detection concepts. We calculated the signal excess (SE) value using SONAR equation, then derived the probability density function(PDF) for target presence($H_1$) or absence($H_0$) cases, respectively. With the Neyman-Pearson detector criterion, we got the probability of detection($P_D$) while satisfying the given probability of false alarm($P_{FA}$). At every instance of simulation, target detection is decided in the probabilistic perspective. With the proposed detection implementation, we improved the model fidelity so that it could support the tactical decision during the operation.