통계적 모형 추정을 통한 서울시 마을버스 교통사고의 업체별 영향요인 분석

권지은,김도경 한국ITS학회 2018 한국ITS학회 학술대회 Vol.2018 No.11

Chapter 47 of the Samguk sagi: An Annotated Translation of Biographies of Haeron and Others

권지은,신정수 한국학중앙연구원 한국학중앙연구원 2020 THE REVIEW OF KOREAN STUDIES Vol.23 No.1

HPLC-UVD를 이용한 농산물 중 Fluxapyroxad 잔류분석법 개발

권지은,김희정,도정아,박혜진,윤지영,이지영,장문익,이규식 한국식품위생안전성학회 2014 한국식품위생안전성학회지 Vol.29 No.3

Fluxapyroxad is classified as carboxamide fungicide that inhibits succinate dehydrogenase in complexII of mitochondrial respiratory chain, which results in inhibition of mycelial growth within the fungus target species. This study was carried out to assure the safety of fluxapyroxad residues in agricultural products by developingan official analytical method. A new, reliable analytical method was developed and validated using High Performanceliquid Chromatograph- UV/visible detector (HPLC-UVD) for the determination of fluxapyroxad residues. The fluxapyroxadresidues in samples were extracted with acetonitrile, partitioned with dichloromethane, and then purifiedwith silica solid phase extraction (SPE) cartridge. Correlation coefficient(R2) of fluxapyroxad standard solution was0.9999. The method was validated using apple, pear, peanut, pepper, hulled rice, potato, and soybean spiked with fluxapyroxadat 0.05 and 0.5 mg/kg. Average recoveries were 80.6~114.0% with relative standard deviation less than10%, and limit of detection (LOD) and limit of quantification (LOQ) were 0.01 and 0.05 mg/kg, respectively. All validationparameters were followed with Codex guideline (CAC/GL 40). LC-MS (Liquid Chromatograph-Mass Spectrometer)was also applied to confirm the analytical method. Base on these results, this method was found to beappropriate fluxapyroxad residue determination and can be used as the official method of analysis.

미숙아의 정맥영양제 투여에 의한 간기능 부작용 발생에 있어서 Fish Oil 함유 대 Soybean Oil 함유 지방유제의 영향비교

권지은,왕선희,박애령,김순주,황보신이,나현오,김은영 한국병원약사회 2017 병원약사회지 Vol.34 No.1

Objective : Parenteral nutrition (PN) is critical for growth and therapeutic effect in premature infants. However, long term PN is associated with development of PN associated liver disease (PNALD). Since the omega-6 fatty acid in soybean oil fat emulsion could be responsible for promoting PNALD, fish oil fat emulsion has been used to reduce this adverse effect. This study aimed to evaluate the efficacy of fish oil fat emulsion in reduction of PNALD. Methods : This study was designed for premature infants who were administered PN with fat emulsion for at least 4 weeks, at the Seoul St. Mary’s hospital neonatal intensive care unit. Between September 2013 and February 2014, preterm infants who received PN with soybean oil fat emulsion were classified as the SO group. From September 2014 to August 2015, preterm infants who received PN with fish oil fat emulsion were classified as the FO group. The change of aspartate transaminase (AST), alanine transaminase (ALT) and direct bilirubin (DB), weight, total protein, albumin and triglyceride (TG) were investigated on the first day and the last day of PN administration. Results : The level of AST decreased by 0.5 IU/L in the FO group, and increased 8.5 IU/L in the SO group (P=0.02). The ALT and DB increased to 13 IU/L and 0.18 mg/dL respectively, in the FO group, and 27.5 IU/L and 0.53 mg/dL respectively, in the SO group (P=0.051, 0.247). No significant difference was observed in weight and total protein. However, the change of albumin levels in the FO group was significantly greater than in the SO group (P=0.01). Also, TG levels decreased by/to 90 mg/dL in the FO group and increased by/to 4.5 mg/dL in the SO group (P=0.03). Conclusion : This study suggests that fish oil fat emulsion lowers the risk of PNALD. Subsequently, fish oil fat emulsion was effective in the improvement of nutritional status in preterm infants.

'SF = 탈인간중심주의'? 필립 K. 딕에 나타난 인간중심주의로의 회귀 욕망

권지은 영미문학연구회 2012 안과 밖 Vol.0 No.33

Among contemporary American novels, Chuck Palahniuk’s Fight Club is one of the interesting examples that present the USA in crisis in both dramatic and shocking ways. As many people have pointed out, crisis has become one of the key terms succinctly defining the present condition of the USA that has been put in serious pitfalls in economy, politics, culture and so on. In Fight Club, his most popular work that has been accepted with cult-like enthusiasm, Chuck Palahniuk brings up issue of white masculinity in decline to focus on the dilemma of the individual who gets lost in consumer capitalist American society. The dilemma is presented through a kind of psychopathic drama of two juxtaposed males,the narrator and Tyler Durden, who turns out the narrator’s alter-ego. It is Tyler who guides the narrator to violence as a way of breaking away from the numbed life in the dominant order of capitalism and further constructing a new world in which those who have been oppressed regain genuine selfhood and freedom. But Tyler is someone who the narrator must necessarily overcome for the revolution of self, as well. As shown through Project Mayhem in particular, Tyler’s fascist enterprise of subverting the capitalist system repeats the very oppressive dominant order that the narrator tries to subvert. After an overview of the significance that Fight Club has in regard to the issues of the USA in crisis, this paper concretely examines the overall process in which the narrator struggles to be redeemed from dehumanizing capitalism. In so doing, as the narrator’s decision to hold the terrorist project suggests at the end of the novel, it explores the paradox of revolution, that is, the impossible possibility of revolution that revolution could be possible because it is impossible now.

영양집중지원팀 자문 순응도에 따른 영양상태 개선효과 비교

권지은,박애령,김순주,나현오 한국병원약사회 2017 병원약사회지 Vol.34 No.2

Purpose : The primary goal of Total parenteral nutrition(TPN) therapy is to supply the nutrients by intravenous injection to the patients who cannot get adequate nourishment by oral. TPN have an affect on the hospital days and the therapeutic effect. In Seoul St. Mary’s hospital, Nutrition support team (NST) performs consultation of nutrition state and monitoring of patients. This study evaluated the effects of NST works through the improvement of nutrition index between compliance group and non-compliance group according to consultation of NST. Methods : We collected retrospectively the data from patients at Seoul St. Mary’s hospital from September 2012 to August 2013, who received TPN therapy and consultation of NST. Patients were categorized according to the adaptation of NST’s consultation. We checked the difference of nutrition index such as total protein, albumin, transferrin, retinol binding protein, and pre-albumin between before the consultation and 14 days after the adaptation of NST. Also we collected the number of administration of albumin in order to evaluate nutrition state of patients. Results : Out of 105 patients who received NST’s consultation, 46 patients were in compliance group and 59 patients were in non-compliance group. Total protein and albumin were increased to 0.3±0.1 and 0.1±0.1 g/dL in compliance group. But there was no change in non-compliance group of 0.0±0.1 and 0.0±0.0 g/dL. These results showed statistically significant difference between compliance group and non-compliance group(P 0.05). In compliance group the average of patient’s serum transferrin, retinol binding protein and pre-albumin were increased to 14.0±7.0, 1.0±0.2 and 3.2±0.7 mg/dL, respectively. In non-compliance group the average of patient’s serum transferrin, retinol binding protein and pre-albumin were decreased to 2.2±3.8, 0.2±0.2 and, 1.7±0.9 mg/dL, respectively. Also these results showed statistically significant difference between compliance group and non-compliance group(P 0.05). The number of administration of albumin was 0.7±1.1 and 1.5±2.5 in compliance group and non-compliance group, respectively(P 0.05). Conclusion : In conclusion, this study suggests that NST’s consultation may give the result for the effective increase of nutrition lab. Therefore the continuing expansion of NST activity can improve the patient’s nutrition state. In order to provide appropriate nutritional management, it is necessary to improve the recognition of medical team for the nutrition support.

정맥영양요법을 시행 중인 고중성지방혈증 환자에서 fish oil이 함유된 지방유제 투여 효과 분석

권지은,오소영,박애령,김순주,나현오 한국병원약사회 2013 병원약사회지 Vol.30 No.5

Intravenous fat emulsion (IVFE) in parenteral nutrition (PN) has an advantage of slipplying essential fatty acids with non-glucose based energy. However, it has been associated with the development of hypertriglyceridemia. The principal management of PN-dependent patients with hypertriglyceridemia is to withhold the IVFE until serum triglyceride (TG) level is normalized. This practice may predispose patients to the development of essential fatty acid deficiency. This study evaluated the effects of fish oil fatty acids on TG levels and liver toxicity in PN dependent hypertriglyceridemia patients. This study included patients who developed TG levels > 400 mg/dL with soybean oil emulsion and then fish oil emulsion in their PN from October 2010 to April 2012 at Seoul St. Mary’s Hospital. The study investigated the differences in TG, aspartate transaminase (AST), alanine transaminase (ALT) and total bilirubin (TB) before and after the regimen change, and evaluated the significance of the differences. A total of 10 patients (6 adults and 4 children) were included. After administration of fish oil IVFE, the average serum TG level was decreased from 451 mg/dL to 250 mg/dL, and this was statistically significanthly different (P=0.006). The average serum AST was increased from 40.5 IU/L to 54.0 IU/L (P=0.910), but the average serum ALT was decreased from 33.5 IU/L to 26.5 IU/L (P=0.508). The average serum TB was increased from 0.7 mg/dL to 0.9 mg/dL (P=0.432). These results showed no statistically significant differences. In conclusion, this study suggests that PN with fish oil emulsion may result in an effective decrease in TG levels. Changes in the liver somatic index did not show statistically significant results. Therefore, we can presume that increased risk of hepatotoxicity did not occur. In order to achieve more accurate and reliable results, it is necessary to conduct randomized controlled trials for evaluating hepatotoxicity of fish oil fatty acids.

Synthesis of Various Polyviologens by Adjusting the Position and Characteristics of Substituent and Analysis of Electrochromic Properties

권지은,이승우,채다정 한국고분자학회 2022 한국고분자학회 학술대회 연구논문 초록집 Vol.47 No.2

『밤은 부드러워 』에 나타난 미국 전통적 역사관의 종말

권지은 현대영미어문학회 2016 현대영미어문학 Vol.34 No.4

This paper aims to explore the concept of history conveyed in Tender Is the Night and examine its political consequences. Dick Diver, the protagonist and a modern American Adam, attempts to create the nation after its own original image of innocence and promise, and by doing so, he tries to re-write the nation’s history as his national predecessors have done. However, all of his attempts to ‘re-write’ the nation’s history by enforcing its fundamental ideal turn out to be futile: he loses his grip not only on Nicole, a symbol of American Innocence, but also on his own personal ability to create the world in the process. By closely examining Diver’s downfall, this paper aims to show that the text proclaims the national project of American Adam and its impulse of creating history as a lost ideal, a national tradition that cannot be retrieved any more

포스트모던 주체를 넘어서: 『유리의 도시』다시 읽기

권지은 현대영미어문학회 2014 현대영미어문학 Vol.32 No.4

The critical attention on Paul Auster's City of Glass has generally focused on how it deconstructs the idea of subjectivity by debunking the myth of authentic self. Against the grain of this critical consent, this paper aims to demonstrate that the overall notion underlying City of Glass is the desire to reconstitute the autonomous self. The matter of subjectivity formation in the text is largely based upon the age-old conflict in American imagination between the individual and the social. By turning the protagonist into an independent individual who voluntarily marginalizes himself from the society, City of Glass reinstates the value of individualism that has been repeatedly circulated in the American political milieu, in which an autonomous individual can be (and should be) a form of effective social critique against the mind-numbing collectivity. By focusing on the constitution of individuality, this paper attempts to show that City of Glass is rather a typical example that faithfully embodies the national ideal of individual dissent, than an innovative way of conceiving the decentered postmodern subjectivity.