마우스에서 조합시험법에 의한 고려홍삼의 생식발생독성 평가

김미라, 박동선, 장자영, 신선희, 이예은, 백인정, 연정민, 이세라 , 남상섭, 황방연, 노재섭, 김순선, 조대현, 남상윤, 이범준, 김윤배, 윤영원 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

카오스와 리아프노프 지수

김연미,유세라 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.1

In this paper, we try to approach chaos with numerical method. After investigating nonlinear dynamics (chaos) theory, we introduce Lyapunov expontent as chaos's index. To lood into the existence of chaos in a 2-dimensional difference equation, we compute Lyapunov exponent and examine various behaviors of solutions by bifurcation map.

유한 차등 방정식과 카오스

김연미,유세라 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

In this paper, we invesitigate the chaotic behavior which occurs if we use Euler's method to approach to the solution of nonlinear differential equation. We consider the several sufficient conditions for the existence of the chaos in finite difference scheme. The result can be applied to 2-dimensional difference equations and euler's difference schemes.

LOGO 프로그램의 기하교육에의 도입과 활용방안

金姸美,李芝瑛 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-

Mathematical visualization is a process to make mathematical images and use the image toward discovery and understanding. Hence, it is not proposed to make visual materials simply, but it has to have a circumstance that explores to visual object. In mathematics education, visualization has been ignored for a long time because people got used to manufacturing number or simbols. Therefore LOGO is a useful program that makes mathematical visualizaion possible for students. The purpose of this study is an application of LOGO program into geometry education through the mathematical visualization.

한국과 미국의 초등학교 수학교육용 학습매체의 비교와 분석

金姸美,李芝瑛 弘益大學校 科學技術硏究所 1999 科學技術硏究論文集 Vol.10 No.1

We have compared and analyzed softwares for mathematics education in Korea and USA. The purpose of this research is to help parents and teachers with selection of softwares and to offer data and information to software designers and companies. Korean softwares are superior than American products in curriculum, American products were found to be superior in motivation and feedback.

부동산금융으로서의 이행인수 : 대법원 2002. 5. 10. 선고 2000다18578판결을 중심으로

김연미,이중기 홍익대학교 2009 홍익법학 Vol.10 No.1

As a method of real estate financing, the buyer may borrow funds by providing security interest on the real estate to be acquired. Furthermore, if the seller has already borrowed money by establishing certain security interest over the real estate subject to the sale, the buyer may assume the seller's obligation under the loan as part of the payment of the purchase price. In this situation, the interests of relevant parties may vary: the buyer wishes to assume the obligation so that she does not have to fund the purchase price through other channel; the seller wishes to get out of the obligation under the loan when she sells the real estate; and the creditor wishes not to jeopardize her interests by change of debtor even if she holds the same security interests. The Supreme Court of Korea, through a series of decisions including the "2000Da18578" Decision, has established that, (a) the true change of debtor occurs only with the consent of the creditor; (b) without the creditor's consent, it is either (A) both the seller and the buyer are jointly liable for the loan, or (B) the seller is still the debtor under the loan, while the buyer has obligation towards the seller to perform the obligation under the loan on behalf of the seller. In case of a project of real estate development (with funding through Project Financing), the treatment of existing loans secured by the real estate is crucial. In this regard, the rules made by the Supreme Court should be re-visited. 부동산 금융의 일환으로 매매목적물인 부동산 자체를 담보로 제공하고 부동산 취득자금을 조달할 수 있으며, 이 경우 매매목적물에 이미 채무가 부담되어 있다면 그러한 채무를 부동산 매수인이 인수하는 방식도 널리 행하여지고 있다. 이러한 매매대금에 갈음한 채무 인수 약정의 경우 그 법형식을 면책적 채무인수로 볼 것인지, 중첩적 채무인수로 볼 것인지, 단순한 이행인수로 볼 것인지에 따라 이해관계자들의 법률관계가 다르게 규정된다. 이 글에서 검토한 대법원 2002.5.10 선고 2000다18578 판결을 포함한 대법원의 일련의 판결들을 검토한 결과, 대법원의 입장은 채무자의 인적 사항의 변동에 따른 채권자의 불이익을 최소화하기 위하여 (ㄱ) 채권자의 승낙이 있으면 면책적 채무인수, (ㄴ) 인수대항인 권리관계가 함께 양도되거나 인수인이 채무부담에 상응하는 대가를 얻은 때에는 병존적 채무인수, (ㄷ) 그 이외의 경우에는 이행인수에 해당한다는 것이다. 그러나 이러한 공식만으로는 모든 사안을 명확히 해결하기 어렵다. 또한 이러한 채무의 인수는 부동산 개발사업에서도 종종 이용되는데, 일반적인 프로젝트 파이낸싱 (Project Financing) 기법과 달리 시공사의 신용보강이 중요한 역할을 하는 우리나라 부동산 개발사업의 특수성에 비추어 볼 때, 이러한 채무 인수약정에 대한 시공사의 책임범위도 검토할 필요가 있다.

한국과 미국의 초등학교 수학 교과서 및 교육과정의 비교와 분석

金姸美,李芝瑛 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

We have compared and analyzed mathematics curriculums for the elementary schools of Korea and USA. We have reviewed them and found some similarities and differences. We strongly believe that the 7th mathematics curriculum of Korea follows the curriculum suggested by NCTM in USA. Both of the curriculums emphasize "mathematical literacy", which means mathematical power. And they've also emphasized to use calculators and computers in a classroom to prepare the 21th century.

인지 심리학의 수학교육에의 적용

金姸美 弘益大學校 科學技術硏究所 2005 科學技術硏究論文集 Vol.16 No.-

There is a frequent misperception that the move from behaviorism to cognitivism implies an abandonment of the possibilities of decomposing knowledge into its elements for purposes of study and decontextualizing these elements for purposes of instruction. We want to show that cognotivism does not imply rejection of decomposition and decontextualization. We study two recent movements related theses- situated learning and constructivism. We show how they affect mathematics education and try to find more productive links between psychology and mathematics education.

국내 설사환자로부터 분리된 Escherichia coli 균의 혈청군 및 Verocytotoxin 생성능

김호훈,강연호,김성한,박미선,유재연,이복권 대한감염학회 1998 감염 Vol.30 No.5

목적: 국내 설사 환자에게서 분리 동정된 인체 감염 유래 E. coli 균의 혈청군, verocytotoxin 생성능을 구명하여 EHEC 균의 인체 감염 실태를 구명하고, 동물 및 식품 유래 분리균주의 성상과 비교 검토하여 인체 감염 위험성에 대한 기초적 자료를 의학계에 제공하고자 하였다. 방법: EHEC 감염의심 설사 환자 분변 검체로부터 분리된 균주 중 생화확적 성상에 따라 대장균을 분리하였고 이들 균주 중 E. coli O157:H7를 분리하기 위해서는 Dsorbitol 음성균을 선별하였으며, 분리균에 대하여 항혈청으로 응집 시험을 실시하여 혈청군을 구명하였다. 혈청군이 확인된 균주에 대하여 중합효소 연쇄반응 (PCR) 및 역수동라텍스 응집시험 (Reversed Passive Latex Agglutination:RPLA) 으로 verocytotoxin 생성능을 구명하였다. 결과: 장출혈성 대장균 감염 의심설사 환자의 분변검체로부터 25주의 E. coli 균을 분리 동정하였으나 이들 균주는 모두 verocytotoxin을 생성하지 않았다. 분리 동정된 대장균으로부터 확인된 혈청군은 16종으로서 E. coli O1, O6, O8, O15, O20, O25 O26, O28, O29, O44, O86a, O119, O126, O128, O152, 및 O157:H-였으며 E. coli O157:H-혈청형 균주와 E.coli O25 혈청군 균주가 각각 3주씩 분리되어 비교적 높은 분리율을 보였다. 결론: 장출혈성 대장균 감염 의심설사 환자 분변 가검물로부터 총 25주의 E. coli균을 분리 동정하였으나 verocytotoxin을 모두 생산하지 않았다. Background: Since 1982, many countries has reported outbreaks or sporadic cases caused by enterohaemorrhagic Escherichia coli (EHEC) serogroup strains, mainly E. coli O157:H7 type strain. However, systemic investigation about EHEC agents, including E. coli O157:H7, have not been done in Korea. Therefore, we investigated serogroup and verotoxin productivity of E. coli strains isolated from diarrheal patients and estimated risk of human infection in comparison with EHEC strains isolated from cow, pig, and food material in Korea. Methods: Diarrheal patient stool samples were collected and E. coli strains were isolated, according to biochemical characteristics. In order to isolate E. coli O157:H7, D-Sorbitol negative strains were selected. Serogrouping of the E. coli isolates was done by agglutination test. Verocytotoxin productivity was investigated by polymerase chain reaction (PCR) and reversed passive latex agglutination (RPLA). Human infection risk was estimated in comparison with EHEC strains isolated from cow, pig and food materials in Korea. Results: Twenty-five E. coli strains were isolated from the diarrheal patients who were suspected to be infected with EHEC. However, none of these E. coli strains produced verocytotoxin. Out of 25 E. coli isolates, 16 serogroups of E. coli O1, O6, O8, O15, O20, O25, O26, O28, O29, O44, O86a, O119, O126, O128, O152 and 157:H-were found. In each of the E. coli O157:H-and O25 serogroups 3 strains were found. Conclusion: None of 25 E. coli isolated from diarrheal patients who were suspected of EHEC infection produced verocytotoxin producing E. coli have been reported recently in Korea.

환자 만족도 조사를 통한 QI활동의 효과 평가 : 일개 병원을 중심으로

박연옥,김미숙,고은정,김연정,홍창호 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.2

Background : Evaluation of patient's satisfaction is one of the most important aspects of quality improvement. If the patient highly satisfies with the medical service provided in the hospital, he/she will be likely to visit the same hospital again. Patient's satisfaction of a particular hospital is directly correlated with hospital profits as well as reputation in the community. For this reason, various kinds of survey measuring satisfaction level have been performed and many kind of QI activities for enhancing the profits as well as reputation in the community. For this reason, various kinds of survey measuring satisfaction level have been performed and many kind of QI activities for enhancing the patient's satisfaction. This study is to find the effect of hospital QI activities on the patient's satisfaction level. Methods : After questionnares were developed, survey of measuring satisfaction level was performed in August. 1998. On the basis of survey results. Ql activities were carried out to attain the target point of 4.0 and subsequent survey was done in November. 1998. Results : With three main principles of "problem solving approach with kindness". "helping patient to participate in medical procedure with sufficient information", and "putting employees into practice of attitude with human respect", the average level of satisfaction was enhanced from 3.45 to 3.55 level. Also kindness level of employees was increased from 3.71 to 3.82. Level of dissatisfaction about insufficient explanation and unkind attitude was dropped from 69% to 48% and from 82% to 46% respectively. Conclusion : With the result of this study overall satisfaction level was enhanced. In order to keep these advantages a operation of Quality Improvement Task Force Team in each subject will be required.