RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 음성지원유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
          펼치기
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • Does a Scale of Failure Affect Learning Effects : Focusing on Small and Large Failure

        장유진,민지홍,김추연,오경석,박나민 한국경영학회 2023 한국경영학회 통합학술발표논문집 Vol.2023 No.8

        Research on failure focuses on failure itself, and focuses on solving problems or fixing defects. Failure is costly and at the same time serves as an opportunity for learning. Recently, business failure is treated as an intangible resource that brings profits to a company. When approaching failure from a fundamental point of view, not all failures are the same. Therefore, it is necessary to enhance the understanding of failure and reduce failure by checking various factors such as the cause and scale of failure. This study aims to see the impact on companies based on the failures that occur in airlines. Specifically, we verify the scale of failure on organizational learning. As a result of studying the effect of organizational learning through failure experience, it can be seen that small-scale failures had a negative effect on organizational learning. However, it was confirmed that large-scale failure have a positive effect on organizational learning. The results of this study have important implications for companies in terms of the consequent event of organizational failure. Learning about the characteristics of failure can prevent the repetition of risk management failure by identifying the cause of organizational learning failure and blocking it, and it will also help to establish a strategy that is advantageous to the company. We hope that this study help enhance our understanding of how firms can learn from failure.

      • KCI등재

        Failure Temperatures of Steel H-Section Columns under Elevated Temperatures

        김재억,강승덕,최현식 한국강구조학회 2014 International Journal of Steel Structures Vol.14 No.4

        This paper introduces the failure temperatures and stresses of H-section columns under elevated temperatures. The failuretests using the heating furnace were performed at the Fire Insurers Laboratories of Korea. The eight specimens fabricated ofSS400 steel were tested and the slenderness ratio, the width-thickness ratio of the flange, and the width-thickness ratio of theweb of all specimens were fixed at 45.4, 10.0 and 26.4, respectively. The specimens loaded by constant compression wereheated until failure occurred. Four types of compressive stresses were selected as initial loading conditions;, these compressivestresses corresponded to 50, 60, 70, and 80% of the yield strength at ambient temperature. The specimens are classified intofour groups according to the initial compressive stress. The compressive stresses which are initially loaded in the tests are alsodefined as the failure stresses at the failure temperatures of specimens. The failure stresses are compared with the linear elasticand nonlinear buckling stresses and the yield stresses (which respond to the failure temperatures) by using the Eurocode 3 Part1.2 which defines the material property of steel under elevated temperatures. The linear local and overall buckling stresses werehigher than the yield stresses at the failure temperatures and the failure phenomenon was caused by nonlinear bucklingoccurring before yielding failure. The failure stresses were lower than the yield stresses obtained by the EC3 at the failuretemperatures. The failure stress ratios of the four groups of specimens loaded as 50, 60, 70, and 80% of ambient yield strengthwere evaluated as 0.78, 0.89, 0.88, and 0.92 of the yield stresses given in EC3, respectively. The nonlinear buckling stressesdefined by EC3 showed about 0.65 of the failure stresses. The four groups of specimens failed at 543.5, 534.5, 489.9, and457.9oC, respectively.

      • SCOPUSKCI등재

        Determination of failure initiation stress and failure grade using Acoustic emission

        Cheon, Dae-Sung,Park, Chan,Synn, Joong-Ho,Jeon, Seok-Won,Park, Hyun-Ik,Park, Yeon-Jun 한국암반공학회 2008 Geosystem engineering Vol.11 No.1

        The excavation of rock structures in hard rock involves three safety issues: structural failure such as wedge-type failures, brittle failures such as slabbing and spalling, and a combination of these two. Especially at highly stressed levels, the failure process of rock structures are mainly affected and eventually dominated by stress-induced fractures growing preferentially parallel to the excavation boundary. This brittle failure is usually occurred within very small displacement or strain, and thus it is not easy to determine the precursor and initiation stress level of failure in displacement detection method. To overcome this problem, some researchers have tried to adopt the acoustic emission (AE) detection. This study carried out physical model experiments and determined brittle failure initiation stress and failure grade, which are the two important characteristics of brittle failure. Failure initiation stress and failure grade are determined using AE detection as well as visual observation. And the locations of failure were detected in real time by the AE source location. This study showed that AE detection method could be usefully applied to determine the brittle failure initiation.

      • 부동산 시장에 있어서 시장의 실패와 정부의 실패

        김상진(Sangjin Kim) 한국부동산경매학회 2023 부동산경매연구 Vol.4 No.1

        소비자들과 생산자들이 자유롭게 경쟁하는 시장에서는 수요와 공급의 원리에 의해 시장가격이 결정된다. 이러한 시장가격은 경제생활에서 희소한 자원을 효율적으로 배분하는 역할을 한다. 까다롭고 성립하기 어려운 조건을 갖춘 완전경쟁시장이라는 이상적인 형태의 시장이 성립하면 효율성이 담보된다는 것을 경제학자들이 증명해냈다. 그러나 성립하기 어려운 조건 때문인지 몰라도 시장에서의 자원배분이 언제나 효율적으로 이루어지는 것은 아니다. 경우에 따라서는 재화와 서비스가 소비자들이 원하는 것보다 적게 생산되기도 하고, 반대로 더 많이 생산되기도 한다. 이때 적게 생산된다는 것은 희소한 자원이 필요한 곳에 충분히 배분되지 않았다는 것을 의미하며, 더 많이 생산된다는 것은 희소한 자원이 불필요하게 낭비된 것이라고 볼 수 있다. 이와 같이 시장에서 가격에 의한 자원 배분이 효율적이지 못한 현상을 ‘시장의 실패’라고 한다. 시장실패의 원인은 불완전경쟁, 공공재, 외부효과, 정보의 비대칭 등이 있다. 시장실패란 어감 때문인지 사람들이 시장경제에서 발생하는 모든 문제점에 대해 시장실패라는 단어를 사용하는 것을 종종 볼 수 있다. 그러나 적어도 경제학의 관점에서 시장실패란 단어는 매우 제한적으로 사용된다. 시장실패란 가격에 의해 자원이 효율적으로 배분되지 못한 상태 이외에 다른 어떤 의미도 포함하지 않는다. 반면 정부실패는 시장에 대한 정부 개입이 오히려 자원의 비효율적 배분으로 이어지는 현상을 지칭한다. 시장실패와 대칭되는 개념이다. 정부실패는 볼프(Wolf)에 의하여 처음 비시장실패라는 용어로 사용되기 시작했으며 정부실패가 초래되는 원인을 초과수요를 발생시키는 정부개입의 수요측면과 정부개입의 공급측면 특성으로 나누어 설명했다. 정부실패의 일반적 원인은 수요와 공급측면의 결합적 성격을 띤다. 원래 시장실패보다 더 치명적인 것이 정부실패다. 시장실패 이론이 나온 이유가 합리적 자원 배분을 왜곡시키는 요인을 찾아 해결하기 위한 것이었다면, 그 핵심적 요인에 이미 정부 리스크가 들어가 있다. 여기에 정부가 이런저런 이유로 시장개입을 강화하고, 공공성의 미명 아래 잘 들지도 않는 칼로 시장을 설 건드리면 정부실패는 예정돼 있다. 정치의 결과로 탄생한 정부는 선거를 생각하는 정치세력의 내부자 논리가 강하고, 따라서 정보를 균형적으로 받아들이기보다는 자신이 원하는 정보만을 취사선택한다. 정권의 지지자들에게 특혜를 주는 방식으로 국가사업을 진행해 자원 배분을 심각하게 왜곡시킬 수 있다. 부동산 관련 법개정이 그 전형적 예이다. 본고는 정부실패가 시장실패에 어떤 영향을 미치는지 부동산시장 법정책을 중심으로 고찰하였다. In a market where consumers and producers compete freely, the market price is determined by the principle of supply and demand. These market prices play a role in efficiently allocating scarce resources in economic life. Economists have proven that efficiency is assured when an ideal form of a perfectly competitive market with difficult and difficult conditions is established. However, although it may be due to difficult conditions, resource allocation in the market is not always efficient. In some cases, goods and services are produced less than consumers want, and vice versa. At this time, being produced less means that scarce resources are not sufficiently distributed where necessary, and being produced more means that scarce resources are wasted unnecessarily. Such a phenomenon in which resource allocation by price is not efficient in the market is called ‘market failure.’ The causes of market failure include imperfect competition, public goods, externalities, and information asymmetry. Perhaps because of the word market failure, we can often see people use the word market failure for all the problems that arise in the market economy. However, at least from an economics point of view, the word market failure is used very limitedly. Market failure does not include any meaning other than the inability to efficiently allocate resources by price. On the other hand, government failure refers to a phenomenon in which government intervention in the market leads to inefficient allocation of resources. It is a concept that is symmetric with market failure. Government failure was first used by C. Wolf as the term non-market failure, and the cause of government failure was based on the demand side of government intervention and the supply side of government intervention that caused excessive demand. I divided and explained. A common cause of government failure is a combination of supply and demand. More fatal than the original market failure is the government failure. If the reason for the market failure theory was to find and solve factors that distort rational resource allocation, government risks are already in the core factors. In addition, if the government strengthens market intervention for one reason or another and touches the market with a knife that is difficult to handle under the name of publicity, the government’s failure is expected. The government, which was born as a result of politics, has a strong insider logic of the political power to think about elections, and therefore chooses only the information it wants rather than accepting information in a balanced way. It can seriously distort the allocation of resources by conducting state projects in a way that gives preferential treatment to the regime’s supporters. Law amendments related to real estate are a typical example. This paper examines the effect of government failure on market failure, focusing on real estate market legal policies.

      • KCI등재

        응력조건에 따른 원형터널 주변의 취성파괴범위와 파괴심도

        천대성(Dae-Sung Cheon),박찬(Chan Park),박철환(Chulwhan Park),전석원(Seokwon Jeon) 한국암반공학회 2007 터널과지하공간 Vol.17 No.4

        경암 내 암반구조물의 파괴는 현지응력의 크기, 무결암의 강도 그리고 암반 내에 존재하는 불연속면의 상태에 의해 결정되며, 특히 높은 현지응력이 작용하는 경우 유도응력에 의해 취성파괴가 발생할 수 있다. 취성파괴의 특성은 파괴수준, 파괴개시시점, 파괴범위와 파괴심도 등으로 구분할 수 있으며, 암반구조물의 안정성을 확보하기 위해서는 응력조건에 따른 취성파괴의 특성을 규명하여야 한다. 본 연구에서는 취성파괴가 발생한 상태에서 응력조건에 따른 파괴범위와 파괴심도를 평가하고자 하였다. 이를 위해 진삼축 압축응력조건에서 모형실험을 수행하였으며, 취성파괴가 발생한 모형실험체에 대하여 육안관찰과 컴퓨터단층촬영을 수행하여 파괴심도와 파괴범위를 결정하였다. 파괴심도는 터널단면에 작용하는 축차응력의 크기에 영향을 받으나 파괴범위의 경우 응력조건에 따른 뚜렷한 경향성을 보이지 않는 것으로 나타났다. Failure of underground structures in hard rocks is a function of the in-situ stress, the intact rock strength and the distribution of fractures in the rock mass. At highly stressed regime, brittle failure is often observed due to excavation-induced stress. The characteristics of brittle failure are classified as failure grade, failure initiation stress, extent of failure and depth of failure. For safety construction of underground structures, these characteristics of brittle failure with stress conditions should be understood. In this study we evaluated the relationship between the extent and depth of failure with stress conditions for failure happened model specimens through true triaxial model experiments. The extent and depth of failure were determined using visual observation and computed tomography (CT). The results indicate that the depth of failure was affected by differential stress perpendicular to the axis of tunnel. However the extent of failure was irrelevant to the stress conditions.

      • KCI등재후보

        Determination of failure initiation stress and failure grade using Acoustic emission

        천대성,신중호,전석원,박현익,박연준,박찬 한국자원공학회 2008 Geosystem engineering Vol.11 No.1

        The excavation of rock structures in hard rock involves three safety issues: structural failure such as wedge-type failures, brittle failures such as slabbing and spalling, and a combination of these two. Especially at highly stressed levels, the failure process of rock structures are mainly affected and eventually dominated by stress-induced fractures growing preferentially parallel to the excavation boundary. This brittle failure is usually occurred within very small displacement or strain, and thus it is not easy to determine the precursor and initiation stress level of failure in displacement detection method. To overcome this problem, some researchers have tried to adopt the acoustic emission (AE) detection. This study carried out physical model experiments and determined brittle failure initiation stress and failure grade, which are the two important characteristics of brittle failure. Failure initiation stress and failure grade are determined using AE detection as well as visual observation. And the locations of failure were detected in real time by the AE source location. This study showed that AE detection method could be usefully applied to determine the brittle failure initiation. The excavation of rock structures in hard rock involves three safety issues: structural failure such as wedge-type failures, brittle failures such as slabbing and spalling, and a combination of these two. Especially at highly stressed levels, the failure process of rock structures are mainly affected and eventually dominated by stress-induced fractures growing preferentially parallel to the excavation boundary. This brittle failure is usually occurred within very small displacement or strain, and thus it is not easy to determine the precursor and initiation stress level of failure in displacement detection method. To overcome this problem, some researchers have tried to adopt the acoustic emission (AE) detection. This study carried out physical model experiments and determined brittle failure initiation stress and failure grade, which are the two important characteristics of brittle failure. Failure initiation stress and failure grade are determined using AE detection as well as visual observation. And the locations of failure were detected in real time by the AE source location. This study showed that AE detection method could be usefully applied to determine the brittle failure initiation.

      • 조기(TNM Stage Ⅰ & Ⅱ) 구강 편평세포암종의 초치료 실패

        이현석(Hyun Seok Lee),정한신(Han Sin Jeong),김태욱(Tae Wook Kim),손영익(Young lk Son),백정환(Chung Hwan Baek) 대한두경부종양학회 2005 대한두경부 종양학회지 Vol.21 No.1

        Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.

      • Impact failure analysis of corrugated steel plate in LNG containment cargo system

        Kim, Myung-Sung,Kwon, Sun-Beom,Kim, Seul-Kee,Kim, Jeong-Hyeon,Lee, Jae-Myung Elsevier 2019 Journal of constructional steel research Vol.156 No.-

        <P><B>Abstract</B></P> <P>In the present study, the failure characteristics of the primary barrier of a GTT Mark-III type liquefied natural gas (LNG) cargo containment system (CCS) under cyclic impact loads were analyzed using a comprehensive failure model. The three types of failure modes that mainly occur in a thin-walled structure, namely, localized necking, ductile failure, and shear failure, were considered to evaluate the different failure phenomena for large and small corrugations of the primary barrier consisting of 304 L stainless steel. To validate the numerical analysis approach, a series of impact tests were conducted, and the reaction force history along with the permanently deformed configuration of the thin-walled structure was compared to the simulation results of structural impact failure. Through the comparative study, it was confirmed that the simulation outcomes were in good agreement with the experimental results. The proposed failure analysis model was used to quantitatively predict the structural impact failure of the primary barrier under severe impact (or sloshing) loads, and the estimated structural life was proposed based on the failure index concept.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Failure prediction model for primary barrier of LNG CCS was proposed. </LI> <LI> Localized necking, ductile failure and shear failure were adopted. </LI> <LI> Reaction force profile and deformation shape of primary barrier were investigated. </LI> <LI> Failure criteria contour of primary barrier was quantitatively evaluated. </LI> <LI> The proposed model showed good agreement with experimental results. </LI> </UL> </P>

      • 대퇴골 간부 골절시 사용한 금속물의 금속부전(Metal failure)의 기전에 대한 연구

        인주철,안면환,안종철,서재성,전춘배 영남대학교 의과대학 1990 Yeungnam University Journal of Medicine Vol.7 No.1

        1983년 5월부터 1989년 9월까지 본 영남의료원 정형외과에 대퇴골 간부골절시 사용한 금속 내 고정물의 금속 부전으로 입원한 경우 중 부전된 금속의 표면관찰이 가능한 8례에 대한 임상적 고찰 및 부전된 금속 파손 표면의 관찰을 통해 확인한 파손 원인을 요약하면 다음과 같다. 1. 금속 부전이 발생 내고정물의 종류는 압박 금속판 5례, Jewett nail 1례, Rowe plate screw 1례, interlocking nail 1례였다. 2. 금속 부전의 임상적 추정에 의한 원인으로는 반대편 피질골 결손 5례, 부적절한 위치선정 1례 및 부적절한 금속선택 1례였다. 3. 금속 내고정후 금속 부전이 되기까지의 기간을 보면, 4개월이 1례, 6개월에서 12개월사이가 6례, 3년이 1례였다. 4. 부전된 내고정물의 파손면 관찰을 통해 학인한 금속부전의 원인을 보면, 첫째, impact failure 1례 둘째, fatigue failure 6례 machining mark가 있어 이것이 stress riser로서 역할을 한 것으로 보이는 경우가 4례였으며, 이의 형태는 low consistent cyclic fatigue failure와 irregular cyclic fatigue failure의 형태를 관찰할 수 있었다. 셋째, Stress corrosion crack 1례를 관찰할 수 있었다. 5. 316L Stainless Steel은 내부식성이 좋은 금속이지만 fretting에 의해 특유의 부동태 피막이 손상되면 pitting corrosion을 일으키며 경우에 따라서는 파손의 기점으로 작용되어 failure의 주요 원인이 되기도 한다. 6. screw hole의 가공시 기계에 의한 손상 및 기구(implant) 제조 과정중 손상이 plate의 failure를 유발하는 중요한 원인이 될 수도 있다. 기계에 의한 손상은 응력을 집중시키므로 plate가 파손되기 쉽게 한다. 이상의 결과 임상적 추정에 의한 원인 이외에도 부전된 금속파손면 관찰을 통해 중요한 다른 원인을 찾을 수 있었으므로, 금속부전의 예방을 위해 앞으로 이 방향으로의 계속적인 연구가 필요할 것으로 사료된다. The author fractographically analyized the cause of metal failure(the first time this procedure has been used for this metal failure)and also analyized it clinically. In this study, I selected eight cases which have been analyized fractographically. In all these cases, the analysis was done after treatment of metal failure of implants internally fixed to femur shaft fractures at the Department of Orthopedic Surgery, Yeung-Nam University Hospital during the six year period from May 1983 to September 1989. 1. Metal failure occured in five dynamic-compression plates, one Jewett nail, one screw in Rowe plate, and one interlocking nail. 2. The clinical cause of metal failure was deficiency of medial butress in five cases, incorrect position of implant in one case, and incorrect selection of implant in two cases. 3. The time interval between internal fixation and metal failure was four months in one case, between five months to twelve months in six cases, three years in one case. 4. The fractographically analytical cause of metal failure was ; first, impact failure, one case, second, fatigue failure, six cases, machining mark(stress liser), four cases type : low consistent cyclic fatigue failure irregular cyclic fatigue failure third, stress corrosion crack, one case. 5. 316L Stainless Steel has good resistance to corrosion. However, when its peculiar surface film is destroyed by fretting, it shows pitting corrosion. This is, perhaps, the main cause of metal failure. 6. It is possible that mechanical injury occured in implants during the manufacturing of implants or that making a screw hole is the main cause of metal failure.

      • SCOPUSKCI등재

        지속성 외래 복막투석 환자에서 한외여과부전의 위험인자 및 임상양상; 투석 도관을 제거한 환자를 대상으로 시행한 환자-대조군 연구

        윤수영 ( Soo Young Yoon ),초소래 ( So Rae Choi ),윤도식 ( Do Sik Yoon ),박형천 ( Hyeong Cheon Park ),강신욱 ( Shin Wook Kang ),최규헌 ( Kyu Hun Choi ),이호영 ( Ho Yung Lee ),한대석 ( Dae Suk Han ) 대한신장학회 2003 Kidney Research and Clinical Practice Vol.22 No.1

        목적 : 한회여과부전은 지속성 외래 복만투석 (CAPD) 환자에서 투석 중단 원인의 20% 가량을 차지하는 매우 중요한 문제이며, 한외여과부전에 기여하는 중요한 인자로는 중증의 반복되는 복막염과 비생리적인 복막액의 장기간 사용 등이 거론되고 있다. 저자 등은 한외여과부전으로 복막투석 도관을 제거한 환자들의 임상양상을 알아보고 한외여과부전의 위험인자를 규명하고자 본 연구를 시행하였다. 방법 : 1990년 1월부터 2000년 12월까지 세브란스병원에서 복막투석을 시작한 환자 중 한회여과부전으로 도관을 제거한 환자 19명을 환자군으로 정하고, 현재 세브란스병원에서 한외여과부전 없이 복막투석을 지속하고 있는 환자 중 환자군과 성별, 연령 그리고 복막투석 시작 시기가 같도록 개별 짝짓기한 76명의 환자를 대조군으로 선정하였다. 복막투석 시작시와 한외여과부전진단시에 복막평형검사를 시행하여 복막의 투과도를 측정하였고, 첫 2년간 잔여신기능과 연간 당부하량을 측정하였다. 복막투석 기간동안 복막염의 빈도와 복막의 축적 염증 기간 (accumulated peritoneal inflammation days, APID), 복막염의 원인 균주 및 베타 차단제 사용 여부를 조사하였다. 복막 기능은 하루 총 한외여과량과 크레아티닌의 질량이동면적계수 (mass transfer area coefficient, MTAC)로 평가하였고, 혈청 알부민, 표준화 단백질 이화률 (normalized protein catabolic rate, nPCR), Kt/V_urea를 측정하였다. 결과 : 한외여과부전 환자군과 대조군에서 원인 신질환이나 복막염의 빈도, APID 및 원인균에 차이는 없었다. 한외여과부전 환자군은 대조군에 비해 복막투석 시작시 복막평형검사상 고복막투석과도를 보이는 환자의 비율에 차이가 없었으나, 한외여과부전 진단시에는 고복막투석과도를 보이는 환자가 더 많았으며 (31.6% vs 10.5%, p<0.05), nPCR이 낮았고 (0.69±0.23 vs 1.02±0.23 g/kg/day, p<0.05), C 반응단백이 높았다 (1.67±3.28 vs 0.50±0.72 mg/L, p<0.05). 혈청알부민의 경우 복막투석 시작 당시에는 두 군간에 차이가 없었으나, 시간이 지남에 따라 환자군에서 대조군에 비해 더 많이 감소하는 경향을 보였고, 도관 제거시에는 유의하게 대조군보다 낮은 농도를 나타냈아(3.1±0.6 vs 3.4±0.4 g/dL, p<0.05). 베타 차단제 사용이나 잔여 신기능 및 잔여 신기능의 감소율은 두 군간에 차이가 없었다. 또한 환자군은 대조군에 비해 크레아티닌의 MTAC가 높았고, 첫 2년간 당부하율이 유의하게 많았다. 한의여과부전의 발생에 독립적으로 영향을 미치는 인자를 규명하고자 다중 희귀분석을 시행한 결과 복막의 포도당 부하량과 당부하량의 증가율이 한외여과부전에 독립적인 영향을 미치는 것으로 규명되었으나 복막의 투과도나 크레아티닌의 MTAC 등은 유의하지 않았다. 결론 : 복막의 포도당 부하량과 당부하량의 증가율이 한외여과부전에 중요한 인자로 작용하는 것으로 생각되며, 한외여과부전으로 진단된 환자는 투석 시작시에 비해 영양상태가 악화되므로 고농도의 포도당 용액의 사용을 최소화하여 한외여과부전을 예방하려는 노력이 필요하다고 사료된다. Purpose : Ultrafiltration (UF) failure is one of the most important causes of CAPD withdrawal accounting for up to 20% of CAPD catheter removal. Factors contributing to RF failure are; severe and multiple peritonitis, continuous exposure to nonphysiologic dialysis solution, and use of β-blockers. We evaluated clinical features of patients with UF failure and assessed the risk factors for UF failure in CAPD patients. Methods : CAPD data of our institution from Jan 1990 to Dec 2000 were anlayzed and a subgroup of 191 patients whose CAPD catheters were removed were collected. Nineteen patients, whose CAPD catheters were removed due to UF failure, were selected from the subgroup as the case group. Seventy six hospital controls without ultrafiltration failure matched for age, sex, and time of CAPD initiation who were currently maintained on CAPD were selected as the control group. Peritoneal equilibration test (PET) was done within 3 months of initiation of CAPD and at the diagnosis of UF failure, respectively. Peritoneal glucose load was estimated for the first twp years. Incidence of peritonitis, accumulated days of peritoneal inflammation (APID), causative organisms of peritonitis, and history of β-blocker use were evaluated. Peritoneal function was determined by daily net ulr\trafiltration and mass transfer area coefficient (MTAC) for creatinine. Serum albumin, normalized protein catabolic rate (nPCR) and Kt/V_urea were also evaluated. Results : There was no difference between cases and controls in etiology of ESRD, peritonitis incidence, APID and causative organisms of peritonitis. The case group included more high transporters at the time of the diagnosis of UF failure. The patients with UF failure showed lower nPCR and higher CRP than controls. Serum albumin level was similar at start of CAPD, but decreased faster in UF failure group. Use of β-blockers and decline in RRF were not different between the two groups. UF failure group had higher MTAC for creatinine and more peritioneal glucose load compared to conrtol group. By logistic regression analysis, peritoneal glucose load and incrernent in glucose load were independent factors associated with UF failure. Conclusion : Peritoneal glucose load and increment of glucose load were found to be important risk factors for UF failure in our study. Therefore, various efforts to reduce peritoneal glucose load in CAPD patients are needed for prevention of UF failure.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼