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      • KCI등재

        Embedded spectral descriptors: learning the point-wise correspondence metric via Siamese neural networks

        Zhiyu Sun,Yusen He,Andrey Gritsenko,Amaury Lendasse,Stephen Baek 한국CDE학회 2020 Journal of computational design and engineering Vol.7 No.1

        A robust and informative local shape descriptor plays an important role in mesh registration. In this regard, spectral descriptors that are based on the spectrum of the Laplace–Beltrami operator have been a popular subject of research for the last decade due to their advantageous properties, such as isometry invariance. Despite such, however, spectral descriptors often fail to give a correct similarity measure for nonisometric cases where the metric distortion between the models is large. Hence, they are not reliable for correspondence matching problems when the models are not isometric. In this paper, it is proposed a method to improve the similarity metric of spectral descriptors for correspondence matching problems. We embed a spectral shape descriptor into a different metric space where the Euclidean distance between the elements directly indicates the geometric dissimilarity. We design and train a Siamese neural network to find such an embedding, where the embedded descriptors are promoted to rearrange based on the geometric similarity. We demonstrate our approach can significantly enhance the performance of the conventional spectral descriptors by the simple augmentation achieved via the Siamese neural network in comparison to other state-of-the-art methods.

      • Optimization for Remote Monitoring Terrestrial Petroleum Pipeline Cathode Protection System Using Graded Network

        Pingting Liu,Zhiyu Huang,Shihong Duan,Zikang Wang,Jie He 보안공학연구지원센터 2015 International Journal of Smart Home Vol.9 No.6

        Method of cathode protection is employed to slow down the corrosion of terrestrial pipe. This paper aims to develop a system to monitor the terrestrial pipe cathode protection equipment to wholly track the operation status of buried pipe timely. The monitoring system integrates technology of wireless sensor networks, GPRS network and Internet not only to collect the cathode potential data in time and realize remote data transmission but also to regulate the guard mode of cathode protection on demand. Optimization mechanisms are adopted to effectively lower the energy assumption and to ensure data transmission reliability, from architecture design, selection of power saving hardware components, implementation of reliable network traffic mechanism including hierarchical network topology with least-complexity cluster head shift strategy, TDMA protocol with auto-adaptive resending scheme, work-on-duty with radio-awaken mechanism and so on. Trial running of the system has published good results with 96% or higher success ratio of data transmission, low power saving and power balance. In all, this system can meet the requirements of timely detecting physical malfunction of terrestrial pipeline and controlling field monitoring system on demand.

      • SCIESCOPUSKCI등재

        American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice

        Chunhao Yu,Xiao-Dong Wen,Zhiyu Zhang,Chun-Feng Zhang,Xiao-Hui Wu,Adiba Martin,Wei Du,Tong-Chuan He,Chong-Zhi Wang,Chun-Su Yuan 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.3

        Background: Colorectal cancer is a leading cause of cancer-related death, and inflammatory bowel disease is a risk factor for this malignancy. We previously reported colon cancer chemoprevention potential using American ginseng (AG) in a xenograft mice model. However, the nude mouse model is not a gutspecific colon carcinogenesis animal model. Methods: In this study, an experimental colitis and colitis-associated colorectal carcinogenesis mouse model, chemically induced by azoxymethane/dextran sodium sulfate (DSS) was established and the effects of oral AG were evaluated. The contents of representative ginseng saponins in the extract were determined. Results: AG significantly reduced experimental colitis measured by the disease activity index scores. This suppression of the experimental colitis was not only evident during DSS treatment, but also very obvious after the cessation of DSS, suggesting that the ginseng significantly promoted recovery from the colitis. Consistent with the anti-inflammation data, we showed that ginseng very significantly attenuated azoxymethane/DSS-induced colon carcinogenesis by reducing the colon tumor number and tumor load. The ginseng also effectively suppressed DSS-induced proinflammatory cytokines activation using an enzyme-linked immunosorbent assay array, in which 12 proinflammatory cytokine levels were assessed, and this effect was supported subsequently by real-time polymerase chain reaction data. Conclusion: AG, as a candidate of botanical-based colon cancer chemoprevention, should be further investigated for its potential clinical utility.

      • KCI등재

        American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice

        Chunhao Yu,Xiao-Dong Wen,Zhiyu Zhang,Chun-Feng Zhang,Xiao-Hui Wu,Adiba Martin,Wei Du,Tong-Chuan He,Chong-Zhi Wang,Chun-Su Yuan 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.1

        Background: Colorectal cancer is a leading cause of cancer-related death, and inflammatory bowel diseaseis a risk factor for this malignancy. We previously reported colon cancer chemoprevention potentialusing American ginseng (AG) in a xenograft mice model. However, the nude mouse model is not a gutspecificcolon carcinogenesis animal model. Methods: In this study, an experimental colitis and colitis-associated colorectal carcinogenesis mousemodel, chemically induced by azoxymethane/dextran sodium sulfate (DSS) was established and theeffects of oral AG were evaluated. The contents of representative ginseng saponins in the extract weredetermined. Results: AG significantly reduced experimental colitis measured by the disease activity index scores. Thissuppression of the experimental colitis was not only evident during DSS treatment, but also very obviousafter the cessation of DSS, suggesting that the ginseng significantly promoted recovery from the colitis. Consistent with the anti-inflammation data, we showed that ginseng very significantly attenuatedazoxymethane/DSS-induced colon carcinogenesis by reducing the colon tumor number and tumor load. The ginseng also effectively suppressed DSS-induced proinflammatory cytokines activation using anenzyme-linked immunosorbent assay array, in which 12 proinflammatory cytokine levels were assessed,and this effect was supported subsequently by real-time polymerase chain reaction data. Conclusion: AG, as a candidate of botanical-based colon cancer chemoprevention, should be furtherinvestigated for its potential clinical utility.

      • SCIESCOPUSKCI등재

        American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice

        Yu, Chunhao,Wen, Xiao-Dong,Zhang, Zhiyu,Zhang, Chun-Feng,Wu, Xiao-Hui,Martin, Adiba,Du, Wei,He, Tong-Chuan,Wang, Chong-Zhi,Yuan, Chun-Su The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.1

        Background: Colorectal cancer is a leading cause of cancer-related death, and inflammatory bowel disease is a risk factor for this malignancy. We previously reported colon cancer chemoprevention potential using American ginseng (AG) in a xenograft mice model. However, the nude mouse model is not a gut-specific colon carcinogenesis animal model. Methods: In this study, an experimental colitis and colitis-associated colorectal carcinogenesis mouse model, chemically induced by azoxymethane/dextran sodium sulfate (DSS) was established and the effects of oral AG were evaluated. The contents of representative ginseng saponins in the extract were determined. Results: AG significantly reduced experimental colitis measured by the disease activity index scores. This suppression of the experimental colitis was not only evident during DSS treatment, but also very obvious after the cessation of DSS, suggesting that the ginseng significantly promoted recovery from the colitis. Consistent with the anti-inflammation data, we showed that ginseng very significantly attenuated azoxymethane/DSS-induced colon carcinogenesis by reducing the colon tumor number and tumor load. The ginseng also effectively suppressed DSS-induced proinflammatory cytokines activation using an enzyme-linked immunosorbent assay array, in which 12 proinflammatory cytokine levels were assessed, and this effect was supported subsequently by real-time polymerase chain reaction data. Conclusion: AG, as a candidate of botanical-based colon cancer chemoprevention, should be further investigated for its potential clinical utility.

      • SCIESCOPUSKCI등재

        American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in Apc<sup>Min/+</sup> mice

        Yu, Chunhao,Wen, Xiao-Dong,Zhang, Zhiyu,Zhang, Chun-Feng,Wu, Xiaohui,He, Xin,Liao, Yang,Wu, Ningning,Wang, Chong-Zhi,Du, Wei,He, Tong-Chuan,Yuan, Chun-Su The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.3

        Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered $Apc^{Min/+}$ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10-20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-$1{\alpha}$ (IL-$1{\alpha}$), IL-$1{\beta}$, IL-6, tumor necrosis factor-${\alpha}$, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

      • KCI등재

        American ginseng significantly reduced the progression of high-fatdiet-enhanced colon carcinogenesis in ApcMin/þmice

        Chunhao Yu,Xiao-Dong Wen,Zhiyu Zhang,Chun-Feng Zhang,Xiaohui Wu,Xin He,Yang Liao,Ningning Wu,Chong-Zhi Wang,Wei Du,Tong-Chuan He,Chun-Su Yuan 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.3

        Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered ApcMin/þ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10e20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-1a (IL-1a), IL-1b, IL-6, tumor necrosis factor-a, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

      • KCI등재

        A new method of synthesis on high-quality AgGaS2 polycrystalline

        Jianjun Zhang,Shifu Zhu,Beijun Zhao,Baojun Chen,Zhiyu He 한국물리학회 2010 Current Applied Physics Vol.10 No.2

        High-pure, single-phase, free of voids and high mass density AgGaS2 polycrystalline was synthesized by a new method, i.e. two-temperature zone vapor-transporting together with the mechanical and melt temperature oscillation method (TVMMTOM), directly from high-purity (6 N) elements silver, gallium and sulfur with excess sulfur. The mechanism and advantages of the new method for synthesizing high-quality AgGaS2 were discussed. It is found that the polycrystalline material synthesized by the new method is superior to that synthesized by the conventional method, what is more the new method can avoid the explosion of the synthetic quartz ampoule. Adopting the modified Bridgman method an integral and crack-free AgGaS2 single crystal with diameter of 14 mm and length of 63 mm has been obtained. It was found that there was a (1 0 1) cleavage face and the four order X-ray spectrum of the {1 0 1} faces was observed. By the method of DSC analysis the melting and freezing points of the AgGaS2 single crystal were about 995 and 955 ℃. The transmission spectra of the AgGaS2 sample of 10 × 8 ×2㎣ were obtained by means of UV and IR spectrophotometer. The limiting wavelength was 470 nm and the band gap was 2.64 eV. It can be found in the infrared spectrum that the infrared transmission was above 55%from 4000 to 800 cm-1, and the infrared transmittance of the crystal is up to 63% at 10.6 lm, which is higher than that of the crystal grown using polycrystalline materials synthesized by the conventional method. The value of a in 10.6 lm was 0.267 cm-1. Above mentioned results showed that the crystal was of good quality and TVMMTOM is preferable for synthesizing high-quality AgGaS2 polycrystalline materials.

      • KCI등재

        Optimization of membrane fouling process for mustard tuber wastewater treatment in an anoxic-oxic biofilm-membrane bioreactor

        Hongxiang Chai,Liang Li,Yinghua Wei,Jian Zhou,Wei Kang,Zhiyu Shao,Qiang He 대한환경공학회 2016 Environmental Engineering Research Vol.21 No.2

        Membrane bioreactor (MBR) technology has previously been used by water industry to treat high salinity wastewater. In this study, an anoxic-oxic biofilm-membrane bioreactor (AOB-MBR) system has been developed to treat mustard tuber wastewater of 10% salinity (calculated as NaCl). To figure out the effects of operating conditions of the AOB-MBR on membrane fouling rate (KV), response surface methodology was used to evaluate the interaction effect of the three key operational parameters, namely time interval for pump (t), aeration intensity (UGr) and transmembrane pressure (TMP). The optimal condition for lowest membrane fouling rate (KV) was obtained: time interval was 4.0 min, aeration intensity was 14.6 m3/(m2¥h) and transmembrane pressure was 19.0 kPa. And under this condition, the treatment efficiency with different influent loads, i.e. 1.0, 1.9 and 3.3 kg COD m-3d-1 was researched. When the reactor influent load was less than 1.9 kg COD m-3d-1, the effluent could meet the third discharge standard of “Integrated Wastewater Discharge Standard”. This study suggests that the model fitted by response surface methodology can predict accurately membrane fouling rate within the specified design space. And it is feasible to apply the AOB-MBR in the pickled mustard tuber factory, achieving satisfying effluent quality.

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