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Hirotaka Hasegawa,Masahiro Shin,Jun Kawagishi,Hidefumi Jokura,Toshinori Hasegawa,Takenori Kato,Mariko Kawashima,Yuki Shinya,Hiroyuki Kenai,Takuya Kawabe,Manabu Sato,Toru Serizawa,Osamu Nagano,Kyoko Ao 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.2
Background and Purpose To assess the long-term outcomes of intracranial dural arteriovenous fistula (DAVF) treated with stereotactic radiosurgery (SRS) alone or embolization and SRS (Emb- SRS) and to develop a grading system for predicting DAVF obliteration. Methods This multi-institutional retrospective study included 200 patients with DAVF treated with SRS or Emb-SRS. We investigated the long-term obliteration rate and obliteration-associated factors. We developed a new grading system to estimate the obliteration rate. Additionally, we compared the outcomes of SRS and Emb-SRS by using propensity score matching. Results The 3- and 4-year obliteration rates were 66.3% and 78.8%, respectively. The post-SRS hemorrhage rate was 2%. In the matched cohort, the SRS and Emb-SRS groups did not differ in the rates of obliteration (P=0.54) or post-SRS hemorrhage (P=0.50). In multivariable analysis, DAVF location and cortical venous reflux (CVR) were independently associated with obliteration. The new grading system assigned 2, 1, and 0 points to DAVFs in the anterior skull base or middle fossa, DAVFs with CVR or DAVFs in the superior sagittal sinus or tentorium, and DAVFs without these factors, respectively. Using the total points, patients were stratified into the highest (0 points), intermediate (1 point), or lowest (≥2 points) obliteration rate groups that exhibited 4-year obliteration rates of 94.4%, 71.3%, and 60.4%, respectively (P<0.01). Conclusions SRS-based therapy achieved DAVF obliteration in more than three-quarters of the patients at 4 years of age. Our grading system can stratify the obliteration rate and may guide physicians in treatment selection.
Yamato Yu,Hasegawa Tomohiko,Yoshida Go,Banno Tomohiro,Oe Shin,Arima Hideyuki,Mihara Yuki,Ushirozako Hiroki,Yamada Tomohiro,Watanabe Yuh,Ide Koichiro,Nakai Keiichi,Kurosu Kenta,Matsuyama Yukihiro 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.5
Study Design: Single-center retrospective case series.Purpose: We aimed to evaluate the clinical results of revision surgery for a rod fracture using a posterior-only approach and determine the best procedure to prevent refracture in patients with adult spinal deformity (ASD).Overview of Literature: ASD affects the thoracolumbar spine and often requires surgical correction. However, surgery for extensive spinal fusion causes rod fracture, a major mechanical complication. Few studies have described the treatment methods for rod fractures. Furthermore, the clinical outcomes of revision surgery for rod fractures in patients with ASD are currently unclear.Methods: We retrospectively reviewed the medical records of 404 patients who underwent corrective fusion surgery for ASD with a minimum 2-year follow-up. We studied cases of reoperation for postoperative rod fractures and investigated surgical procedure, intraoperative findings, clinical course, and rod refracture following revision surgery.Results: Rod fracture was observed in 88 patients (21.8%). Fifty-three patients (average age, 68.3 years; average blood loss, 502.2 mL [% estimated blood volume=16.4%]; and operation time, 203.3 minutes) who suffered from a rod fracture at an average of 28.3 months after the primary operation underwent reoperation. Surgical invasiveness had no significant differences in total or partial rod replacement; however, the procedures with and without an anterior bone graft significantly differed. The replaced rod refractured at an average of 35.3 months after the revision surgery of five patients. The rod also refractured at a level outside multiple rods in two patients and with traumatic episodes in three patients. Three patients had bone grafts in the anterior column.Conclusions: Revision surgery involving a multirod with a posterior-only approach for a rod fracture that occurred after ASD was performed successfully. Bone grafting in the anterior column is unnecessary for patients without massive bone defects.
Yusuke Umahashi,Yuki Kambayashi,Masaru Kato,Yohei Hasegawa,Hideharu Amano,Kimiyoshi Usami 대한전자공학회 2008 ITC-CSCC :International Technical Conference on Ci Vol.2008 No.7
When the dynamic reconfigurable processors run, a lot of Processing Elements (PE) are changed by the context which is written information of circuit configuration. Some PEs execute heavy operations, while other PEs execute light operation. Therefore, the delay time of each PE changes with the contexts. We propose a technique to dynamically change dual supply voltages at each PE. First, we calculate the delay of each PE under the context. Next, we define the standard delay. The standard delay is the longest delay of each PE. Then we assign the standard or lower voltage to each PE. If the PE’s delay at the lower voltage is longer than the standard, this PE is assigned the standard voltage. If shorter than the standard delay, this PE is assigned the lower voltage. Finally, we calculate the power consumption with the technique of dual supply voltage by using the number of assignment the each voltage. When the same voltage was assigned to, the power consumption was reduced by 18.7%. When the voltage is assigned PE-by-PE individually, the power consumption was reduced by 20.3%.
김종훈,Toshio Hasegawa,Kurisu Tada,Yuki Uehara,Yukiko Fukui,Ayako Nakamura,Satomi Takei,Satoshi Mitarai,Akio Aono,Shigaku Ikeda 대한피부과학회 2023 Annals of Dermatology Vol.35 No.-
A 38-year-old female with systemic lupus erythematosus (SLE) initiated belimumab treat- ment. One month later, she presented with a reddish painful swelling on her right lower leg. She was treated with ceftriaxone and vancomycin. However, novel erythematous papules and indurated nodules appeared on both her lower legs. Skin biopsy revealed microabscess formation with mixed cell granuloma surrounded by inf lammatory cell infiltration within the dermis with subcutaneous fat tissue. A large number of acid-fast bacilli were observed with Ziehl–Neelsen staining. DNA sequencing of both the hsp65 and the 16S rRNA se- quences showed a 100% match with the corresponding region of Mycobacterium hae- mophilum . Mycobacterial culture revealed satellite growth enhancement on Middlebrook 7H11 agar plates around a paper strip containing hemin. She was treated with levof loxacin, rifabutin, and ethambutol. Within 13 months, her cutaneous lesions improved markedly without any side effects. The B cell-targeted biologic belimumab, a fully humanized IgG1γ monoclonal antibody that inactivates B lymphocyte stimulator, has been considered to be beneficial for active SLE. However, this therapy could increase the risk for the development of biologic therapy-associated mycobacterial infections, both tuberculosis and nontubercu- lous mycobacteria infections.
Association between Pelvic Parameters and Vaginal Delivery
Yamada Tomohiro,Yamato Yu,Hasegawa Tomohiko,Yoshida Go,Yasuda Tatsuya,Banno Tomohiro,Arima Hideyuki,Oe Shin,Mihara Yuki,Ushirozako Hiroki,Ide Koichiro,Watanabe Yuh,Hosino Hironobu,Matsuyama Yukihiro 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.2
Study Design: Cross-sectional study. Purpose: To investigate the association between vaginal delivery and pelvic parameters and clarify the effect of parity on parameter fluctuations. Overview of Literature: During vaginal delivery, the sacroiliac joint widens and the sacrum nutates (nods). However, the association between these pelvic parameters and parity is unknown. Methods: As part of a 2016 health screening, 320 female volunteers underwent whole-spine radiographs. Age-matched healthy women were grouped according to the number of vaginal deliveries (0, 1–2, or ≥3). Demographic variables and spinopelvic parameters were compared among the three groups. Results: Of the 320 volunteers, 213 were enrolled (mean age, 71.1±7.2 years). The mean number of vaginal deliveries was 2.2. The average pelvic incidence (PI) was 55.6°±11.1° and was significantly higher in the 90 women with three or more vaginal deliveries than in the other two groups (p<0.001). The average sacral slope was 33.4°±11.1° and was significantly higher in the women with three or more vaginal deliveries than in the 18 who did not deliver vaginally (p<0.001). The 105 women with one or two vaginal deliveries had significantly higher PIs and sacral slopes than did those who did not deliver vaginally (p<0.001). Conclusions: This is the first study documenting an association between vaginal delivery and pelvic parameters. Bony birth canal realignment during vaginal delivery can affect postnatal PI. Our study helps in understanding the PI changes over a woman’s life span.
OBSERVATIONAL EVIDENCE FOR AN IMPACT ON THE MAIN-BELT ASTEROID (596) SCHEILA
Ishiguro, Masateru,Hanayama, Hidekazu,Hasegawa, Sunao,Sarugaku, Yuki,Watanabe, Jun-ichi,Fujiwara, Hideaki,Terada, Hiroshi,Hsieh, Henry H.,Vaubaillon, Jeremie J.,Kawai, Nobuyuki,Yanagisawa, Kenshi,Kuro IOP Publishing 2011 ASTROPHYSICAL JOURNAL LETTERS - Vol.740 No.1
<P>An unexpected outburst was observed around (596) Scheila in 2010 December. We observed (596) Scheila soon after the impact using ground-based telescopes. We succeeded in the detection of a faint linear tail after 2011 February, which provides a clue to determine the dust ejection date. It is found that the dust particles ranging from 0.1-1 mu m to 100 mu m were ejected into the interplanetary space impulsively on December 3.5 +/- 1.0 day. The ejecta mass was estimated to be (1.5-4.9) x 10(8) kg, suggesting that an equivalent mass of a 500-800 m diameter crater was excavated by the event. We also found that the shape of the light curve changed after the impact event probably because fresh material was excavated around the impact site. We conclude that a decameter-sized asteroid collided with (596) Scheila only eight days before the discovery.</P>
Yoshida Go,Ushirozako Hiroki,Hasegawa Tomohiko,Yamato Yu,Yasuda Tatsuya,Banno Tomohiro,Arima Hideyuki,Oe Shin,Mihara Yuki,Yamada Tomohiro,Ide Koichiro,Watanabe Yuh,Ushio Takasuke,Matsuyama Yukihiro 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.3
Study Design: Single-center prospective study.Purpose: To investigate anterior spinal artery (ASA) status using preoperative selective angiography in patients undergoing surgery for thoracic ossification of the posterior longitudinal ligament (T-OPLL).Overview of Literature: Surgery for T-OPLL has a high risk of neurological complications, which might be associated with insufficient spinal cord blood flow.Methods: This study prospectively examined nine T-OPLL patients who underwent posterior thoracic decompression with kyphosis correction and instrumented fusion at Hamamatsu University School of Medicine between 2017 and 2019. All underwent preoperative selective angiography to detect and evaluate the Adamkiewicz artery and ASA. Intraoperative neuromonitoring and Doppler ultrasonography were performed to analyze neurological complications and spinal cord blood flow.Results: All nine patients showed ASA stenosis in the area of T-OPLL. In all patients, the Adamkiewicz artery was located between T7 and L2 and the area of ASA stenosis corresponded to the level of T-OPLL and greatest spinal cord compression; intraoperative Doppler ultrasonography confirmed the ASA defect at the same spinal level. The number of spinal levels from the Adamkiewicz artery to the most compressive OPLL lesion was greater in the two patients who developed postoperative neurological deficit compared to those who did not (5.5 vs. 2.3, p=0.014).Conclusions: This is the first study to report detection of ASA stenosis in patients with T-OPLL. Maintaining spinal cord blood flow is important in these patients to avoid neurological deterioration.
INTERPRETATION OF (596) SCHEILA'S TRIPLE DUST TAILS
Ishiguro, Masateru,Hanayama, Hidekazu,Hasegawa, Sunao,Sarugaku, Yuki,Watanabe, Jun-ichi,Fujiwara, Hideaki,Terada, Hiroshi,Hsieh, Henry H.,Vaubaillon, Jeremie J.,Kawai, Nobuyuki,Yanagisawa, Kenshi,Kuro IOP Publishing 2011 ASTROPHYSICAL JOURNAL LETTERS - Vol.741 No.1
<P>Strange-looking dust cloud around asteroid (596) Scheila was discovered on 2010 December 11.44-11.47. Unlike normal cometary tails, it consisted of three tails and faded within two months. We constructed a model to reproduce the morphology of the dust cloud based on the laboratory measurement of high-velocity impacts and the dust dynamics. As a result, we succeeded in reproducing the peculiar dust cloud by an impact-driven ejecta plume consisting of an impact cone and downrange plume. Assuming an impact angle of 45 degrees, our model suggests that a decameter-sized asteroid collided with (596) Scheila from the direction of (alpha(im), delta(im)) = (60 degrees, -40 degrees) in J2000 coordinates on 2010 December 3. The maximum ejection velocity of the dust particles exceeded 100 m s(-1). Our results suggest that the surface of (596) Scheila consists of materials with low tensile strength.</P>
Banno Tomohiro,Yamato Yu,Hasegawa Tomohiko,Yoshida Go,Arima Hideyuki,Oe Shin,Mihara Yuki,Ide Koichiro,Watanabe Yuh,Kurosu Kenta,Nakai Keiichi,Matsuyama Yukihiro 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.1
Study Design: This is a retrospective study.Purpose: This study aimed to investigate the incidence of and risk factors for postoperative shoulder imbalance (PSI) in patients with Lenke type 1.Overview of Literature: PSI is a complication resulting in poor self-image and satisfaction in adolescent idiopathic scoliosis (AIS) patients.Methods: We examined the data of AIS patients with Lenke type 1 curves who underwent posterior fusion surgery in a retrospective manner. PSI was defined as a 2-year postoperative absolute radiographic shoulder height (RSH) of ≥2 cm. Patients were divided into two groups based on the presence of PSI and the level of their upper instrumented vertebra (UIV) (UIV at T2 or T3 [U-UIV] or UIV below T3 [L-UIV]). The radiographic parameters and clinical outcomes were compared, and the cutoff values of risk factors were identified by multivariate analysis.Results: Of 104 patients, 21 (20.2%) had left shoulder elevation PSI. The PSI group had a significantly greater preoperative RSH (−5.1 mm vs. −14.3 mm) and main thoracic (MT) curve correction rate (77.3% vs. 69.1%) than the non-PSI group. The PSI incidence did not differ between the U-UIV and L-UIV groups. Multivariate analysis identified preoperative RSH and the MT curve correction rate as independent risk factors for PSI. The receiver operating characteristic curve analysis identified the preoperative RSH cutoff value as −6.5 mm and MT curve correction rate cutoff value as 76.9%.Conclusions: Even in AIS patients with Lenke type 1 curves, the incidence of PSI was relatively high (20.2%). Patients with preoperative lower right shoulder elevation (i.e., RSH >−6.5 mm) had a higher risk of PSI regardless of UIV level when the MT curve showed a higher correction rate (i.e., correction rate >76.9%).