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      • KCI등재후보

        Interaction between ultrafine ceria particles and glycine

        Yoshihiro Hirata,Hisanori Shimazu,Hideyuki Takahashi,Soichiro Sameshima 한양대학교 세라믹연구소 2004 Journal of Ceramic Processing Research Vol.5 No.1

        An ultrafine ceria powder of 15 nm equivalent spherical particle diameter was dispersed at 2 vol% solid in aqueous solutions with and without glycine (H2NCH2COOH) of 0.05-5.0 mass% against ceria. The addition of glycine increased the zeta potential of the ceria toward positive values in acidic suspensions. The phase separation of ceria suspensions due to the decreased repulsive energy with decreasing particle size, was suppressed by the steric stabilization effect of the adsorbed glycine. No significant influence of the glycine addition on the zeta potential and phase separation of the basic suspension was measured.

      • SCISCIESCOPUS

        Analysis of Internal-Tin <inline-formula> <tex-math notation='TeX'> <tex> $\hbox{Nb}_{3}\hbox{Sn}$ </tex> </tex-math></inline-formula> Conductors for ITER Central Solenoid

        Suwa, Tomone,Nabara, Yoshihiro,Ozeki, Hidemasa,Hemmi, Tsutomu,Isono, Takaaki,Takahashi, Yoshikazu,Kawano, Katsumi,Oshikiri, Masayuki,Tsutsumi, Fumiaki,Shibutani, Kazuyuki,Nunoya, Yoshihiko,Okuno, Kiyo Institute of Electrical and Electronics Engineers 2015 IEEE transactions on applied superconductivity Vol.25 No.3

        <P>Japan Atomic Energy Agency (JAEA) is procuring 100% of the ITER Central Solenoid (CS) conductors. The CS conductor is required to maintain the performance under 60000 pulsed electromagnetic cycles. JAEA tested two internal-tin Nb<SUB>3</SUB>Sn conductors for the CS at the SULTAN test facility. As a result of destructive examination, the twist pitches of both of the cables satisfied requirements of the ITER Organization (IO). The current sharing temperatures T<SUB>cs</SUB> of each sample were 6.6 and 6.8 K before cyclic operation, and the T<SUB>cs</SUB> values were 6.8 and 6.9 K after 9700 electromagnetic cycles, including three warm-up/cooldowns, respectively. The T<SUB>cs</SUB> performance of both samples satisfied the IO requirement. The ac losses of CSKO1-C and CSKO1-D were approximately half of typical bronze-route CS conductors at 2 and 9 T. The ac loss at 45.1 kA after the cycling was 1.5 times higher than that without the transport current. An almost constant strain of the jacket was observed after the test as a result of the residual strain measurement. Therefore, the deformation of the cable might have been homogeneous along the conductor axis. Because of the higher T<SUB>cs</SUB> of CSKO1-D than CSKO1-C, JAEA started the manufacturing of the CS conductor with the same specification as CSKO1-D.</P>

      • The Influence of Laterality during Gait Cycle on Manual Pushing

        ( Kadek Heri Sanjaya ),( Yoshika Takahashi ),( Soomin Lee ),( Yoshihiro Shimomura ),( Tetsuo Katsuura ) 한국감성과학회 2014 춘계학술대회 Vol.2014 No.-

        The objective of this study was to investigate the influence of laterality in various speeds of gait cycle on manual pushing which has been given less attention. The participants of this study were 17 healthy males, 6 of them were left-handers. They performed trials by pushing a wall force plate during walking on a treadmill in three speeds: 1.5, 3, and 4 km/h. The participants were instructed to push at no less than 50% of their maximum static pushing force. Electromyogram (EMG) data was collected bilaterally from tibialis anterior, soleus, lumbar erector spinae and triceps brachii muscles. Time series analysis was normalized into gait cycle which was described as time between heel strike and just before the next heel strike of the same foot and it consisted of 100 data points. To show symmetry, cross-correlation function analysis from the left and right gait cycle variables were compared. Asymmetrical gait cycle period was only observed among right-handers at 3 km/h speed where right gait cycle had longer time than left gait cycle. Pushing force symmetry index was not changed in all of the three speeds in both right-handers and left-handers. Pushing force exertion showed asymmetry in between left and right gait cycle in 4 km/h pushing. The activation pattern of tibialis anterior, soleus and lumbar erector spinae muscles did not show any significant change due to different speeds of manual pushing.

      • KCI등재

        Exceedance probability as a tool to evaluate the wind environment of urban areas

        Mahmoud Bady,Shinsuke Kato,Yoshihiro Ishida,Hong Huang,Takeo Takahashi 한국풍공학회 2008 Wind and Structures, An International Journal (WAS Vol.11 No.6

        The present study aims to estimate the wind ventilation performance for pedestrian level domains from the air quality point of view. Three typical models of a dense urban area were considered and numerically simulated in order to examine the effects of the geometry of such models on wind flow characteristics, which in turn affect the air quality, within the pedestrian domain of a street canyon located within this area. The calculated flow fields were employed to estimate the exceedance probabilities within the study domain using a new approach: air exchange rate within the domain. The study has been applied to nine cities in Japan: Tokyo, Osaka, Sapporo, Niigata, Fukuoka, Nagoya, Sendai, Yokohama, and Kyoto, based on their mean wind velocity data. The results demonstrated that the exceedance probability analysis of the pedestrian wind environment could be a valuable tool during the design stage of inhabited areas for the evaluation of pollutant-removal efficiency by the applied wind. Also, the calculated probabilities demonstrated substantial dependence on both the geometry of building arrays and the wind conditions of the nine cities.

      • The Influence of Laterality during Gait Cycle on Manual Pushing

        Kadek Heri Sanjaya,Yoshika Takahashi,Soomin Lee,Yoshihiro Shimomura,Tetsuo Katsuura 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

        The objective of this study was to investigate the influence of laterality in various speeds of gait cycle on manual pushing which has been given less attention. The participants of this study were 17 healthy males, 6 of them were left-handers. They performed trials by pushing a wall force plate during walking on a treadmill in three speeds: 1.5, 3, and 4 km/h. The participants were instructed to push at no less than 50% of their maximum static pushing force. Electromyogram (EMG) data was collected bilaterally from tibialis anterior, soleus, lumbar erector spinae and triceps brachii muscles. Time series analysis was normalized into gait cycle which was described as time between heel strike and just before the next heel strike of the same foot and it consisted of 100 data points. To show symmetry, cross-correlation function analysis from the left and right gait cycle variables were compared. Asymmetrical gait cycle period was only observed among right-handers at 3 km/h speed where right gait cycle had longer time than left gait cycle. Pushing force symmetry index was not changed in all of the three speeds in both right-handers and left-handers. Pushing force exertion showed asymmetry in between left and right gait cycle in 4 km/h pushing. The activation pattern of tibialis anterior, soleus and lumbar erector spinae muscles did not show any significant change due to different speeds of manual pushing. However, triceps brachii showed differences due to speeds among left-handers. The better understanding of laterality on manual pushing will help in not only better design of manual pushing tools and tasks but also on its application beyond manual materials handling.

      • KCI등재

        Basic Verification of β-D Glucan in Leukocyte-Rich Plasma for the Diagnosis of Deep Mycosis

        Shimoyama Ken,Kan Shigenori,Takahashi Gaku,Morino Gota,Yamada Yasuhiko,Inoue Yoshihiro,Inada Katsuya,Endo Shigeatsu 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.1

        Background: Currently, supplementary serological testing for β-D glucan (BDG) is often selected to diagnose deep mycosis in care covered by the health insurance in Japan. The Wako method used by our center has low sensitivity, and different studies have used different cut-off values due to factors that cause false positives and false negatives. One possible cause of false negatives is the use of platelet-rich plasma (PRP) as the sample material. Because phagocytic white blood cells (WBC) are precipitated by centrifugation and only plasma is measured, it seems unlikely that the actual amount of BDG is being measured when using PRP. Further, a frequent cause of false positives is contamination from blood products and gauze containing BDG. To resolve these issues, the blood cell separator, hydroxyethyl starch, is used to precipitate only the red blood cells to obtain leukocyte-rich plasma (LRP). We hypothesized that it might be possible to improve the diagnostic rate of deep mycosis by measuring the BDG content of plasma containing WBC and fungal components and by comparing the BDG content of PRP and LRP measured simultaneously. Materials and Methods: Healthy human blood, albumin-added blood, wrung-out gauze fluid-added blood, and fungal solution-added blood were prepared, and PRP and LRP were prepared using hydroxyethyl starch. The BDG content of each sample was measured using the Wako method and compared. In addition, PRP and LRP of fungal-added blood were Gramstained and examined under a microscope, and the number of WBCs and phagocytosed fungi was counted visually and compared. Results: Measuring the BDG content of LRP confirmed that there were no false positives with LRP, and in vitro experiments comparing albumin-added false-positive blood to fungal-added blood showed significant differences between PRP and LRP only in the fungal-added blood. Conclusion: Calculating the BDG-ratio (LRP/PRP) by measuring both LRP and PRP may eliminate false positives and false negatives of true deep mycosis and improve the diagnostic rate.

      • SCIESCOPUS

        Exceedance probability as a tool to evaluate the wind environment of urban areas

        Bady, Mahmoud,Kato, Shinsuke,Ishida, Yoshihiro,Huang, Hong,Takahashi, Takeo Techno-Press 2008 Wind and Structures, An International Journal (WAS Vol.11 No.6

        The present study aims to estimate the wind ventilation performance for pedestrian level domains from the air quality point of view. Three typical models of a dense urban area were considered and numerically simulated in order to examine the effects of the geometry of such models on wind flow characteristics, which in turn affect the air quality, within the pedestrian domain of a street canyon located within this area. The calculated flow fields were employed to estimate the exceedance probabilities within the study domain using a new approach: air exchange rate within the domain. The study has been applied to nine cities in Japan: Tokyo, Osaka, Sapporo, Niigata, Fukuoka, Nagoya, Sendai, Yokohama, and Kyoto, based on their mean wind velocity data. The results demonstrated that the exceedance probability analysis of the pedestrian wind environment could be a valuable tool during the design stage of inhabited areas for the evaluation of pollutant-removal efficiency by the applied wind. Also, the calculated probabilities demonstrated substantial dependence on both the geometry of building arrays and the wind conditions of the nine cities.

      • KCI등재

        The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis

        Kazuhide Inage,Sumihisa Orita,Kazuyo Yamauchi,Yoshihiro Sakuma,Go Kubota,Yasuhiro Oikawa,Takeshi Sainoh,Jun Sato,Kazuki Fujimoto,Yasuhiro Shiga,Kazuhisa Takahashi,Seiji Ohtori 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.3

        Study Design: Retrospective study. Purpose: We conducted a study to investigate the time course changes in bone metabolic markers after the administration of the anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody and to assess drug compliance among osteoporotic patients. Overview of Literature: The anti-RANKL antibody is expected to provide an improvement in those with a bone metabolism disorder. However there are only a few clinical reports available on the effect of treatment. Methods: We included 40 post-menopausal osteoporotic patients who received the anti-RANKL antibody. To determine the time course changes in the bone metabolic markers, we measured the serum tartrate-resistant acid phosphatase 5b (TRACP 5b; a bone resorption marker) and the serum N-terminal propeptide of type 1 collagen (P1NP; a bone formation marker) levels prior to and 1 month after administrating the anti-RANKL antibody. To evaluable drug compliance, we assessed the dropout rate during treatment and at 6 months after treatment. Results: The average TRACP 5b level significantly decreased from 574.8 mU/dL before treatment to 153.2 mU/dL 1 month after treatment (p <0.05). There was no significant difference in the average P1NP level, which was 56.9 μG/L and 35.1 μG/L before and 1 month after treatment, respectively (p >0.05). As for drug compliance, we did not have any dropouts during the treatment or after 6 months (dropout rate: 0%). Conclusions: Our study suggests that anti-RANKL antibody treatment suppresses bone resorption and maintains bone formation.

      • Ergonomic Study of Mattress Firmness by Measuring Spinal Curve and Sleep Quality

        Tetsuo Katsuura,Masaki Teshima,Yali Xia,Soomin Lee,Yoshika Takahashi,Ikuo Asai,Yoshihiro Shimomura 대한인간공학회 2014 대한인간공학회 학술대회논문집 Vol.2014 No.5

        We examined the influence of mattress firmness on the spinal curve, sleep quality, and subjective evaluations in healthy subjects. The firmness of the three equal parts of air /mattress was controlled by the air pressure in each part. In Experiment 1, we created nine air mattress conditions by setting the air pressure of each of the upper and middle parts at 4, 6, or 8 kPa, and that of the lower part at 6 kPa. We measured the spinal curves of 10 healthy young male subjects from the coccyx to the 7th cervical vertebra by a fiber optic-based 3D bend and twist sensor, while they laid down on their right side with the angle of the trunk and thigh at 135° (abbreviated as lying135°) and when they laid supine, in each of the nine mattress conditions. We found that the spinal curve during supine position with the conditions of lower part: 6 kPa, middle: 4 kPa, and upper: 6 kPa (“6:4:6”) was the most similar to that during lying135°, which makes the spinal curve natural. However, the subjective evaluation of "comfort of the mattress" by a visual analog scale (VAS) scored highest in the 6:4:8 condition. As Experiment 2, we compared sleep quality achieved with the 6:4:6 and 6:4:8 conditions over each of seven consecutive nights (three adaptation nights and four for analysis) in subjects’ homes. The sleep quality achieved by 20 healthy adult males and females was assessed by means of actigraphy, the standardized Oguri-Shirakawa-Azumi (OSA) Sleep Inventory (middle-aged version), and VAS subjective evaluations. The estimated sleep quality measured on the 6:4:6 mattresses was significantly higher than that on the 6:4:8 mattress. The VAS evaluations of "comfort of the lower back" and "comfort of the upper back" were also higher for the 6:4:6 mattress. There were no significant differences in the OSA scores between mattress conditions. Our results indicate that the 6:4:6 mattress condition, which appeared to provide a natural spinal curve, provided higher sleep quality and higher subjective evaluations during actual use compared to the 6:4:8 condition.

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