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투명하고 유연한 전도성 탄소나노튜브-폴리이미드 복합 필름 개발
오윤주(Yoonju Oh),송승현(Seung Hyun Song),배준호(Joonho Bae) 대한전자공학회 2021 대한전자공학회 학술대회 Vol.2021 No.6
Transparent and electrical conductivity films are in demand for flexible electronic applications. With polyimide (PI) as a substrate, high transparency, electrical conductivity, and flexibility film are manufactured using carbon nanotube. Characteristics of the CNT-PI films show that the film has potential as an electronic application with a flexible and electrical conductivity property.
Jin Yong Kim,Pyoeng Gyun Choe,Yoonju Oh,Kyung Joong Oh,Jinsil Kim,So Jeong Park,Ji Hye Park,Hye Kyoung Na,Myoung-don Oh 대한의학회 2020 Journal of Korean medical science Vol.35 No.5
In December 2019, a viral pneumonia outbreak caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV), began in Wuhan, China. We report the epidemiological and clinical features of the first patient with 2019-nCoV pneumonia imported into Korea from Wuhan. This report suggests that in the early phase of 2019-nCoV pneumonia, chest radiography would miss patients with pneumonia and highlights taking travel history is of paramount importance for early detection and isolation of 2019-nCoV cases.
Hand-crafted 특징 및 머신 러닝 기반의 은하 이미지 분류 기법 개발
오윤주,정희철,Oh, Yoonju,Jung, Heechul 대한임베디드공학회 2021 대한임베디드공학회논문지 Vol.16 No.1
In this paper, we develop a galaxy image classification method based on hand-crafted features and machine learning techniques. Additionally, we provide an empirical analysis to reveal which combination of the techniques is effective for galaxy image classification. To achieve this, we developed a framework which consists of four modules such as preprocessing, feature extraction, feature post-processing, and classification. Finally, we found that the best technique for galaxy image classification is a method to use a median filter, ORB vector features and a voting classifier based on RBF SVM, random forest and logistic regression. The final method is efficient so we believe that it is applicable to embedded environments.
Chung, Su Jin,Lee, Yoonju,Oh, Jungsu S.,Kim, Jae Seung,Lee, Phil Hyu,Sohn, Young H. Elsevier 2018 Parkinsonism & related disorders Vol.53 No.-
<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>The present study aimed to investigate whether the level of presynaptic dopamine neuronal loss predicts future development of wearing-off in <I>de novo</I> Parkinson's disease.</P> <P><B>Methods</B></P> <P>This retrospective cohort study included a total of 342 non-demented patients with <I>de novo</I> Parkinson's disease who underwent dopamine transporter positron emission tomography scans at their initial evaluation and received dopaminergic medications for 24 months or longer. Onset of wearing-off was determined based on patients' medical records at their outpatient clinic visits every 3–6 months. Predictive power of dopamine transporter activity in striatal subregions and other clinical factors for the development of wearing-off was evaluated by Cox proportional hazard models.</P> <P><B>Results</B></P> <P>During a median follow-up period of 50.2 ± 18.9 months, 69 patients (20.2%) developed wearing-off. Patients with wearing-off exhibited less dopamine transporter activity in the putamen, particularly the anterior and posterior putamens, compared to those without wearing-off. Multivariate Cox proportional hazard models revealed that dopamine transporter activities of the anterior (hazard ratio 0.556; <I>p</I> = 0.008) and whole putamens (hazard ratio 0.504; <I>p</I> = 0.025) were significant predictors of development of wearing-off. In addition, younger age at onset of Parkinson's disease, lower body weight, and a motor phenotype of postural instability/gait disturbance were also significant predictors for development of wearing-off.</P> <P><B>Conclusion</B></P> <P>The present results provide <I>in vivo</I> evidence to support the hypothesis that presynaptic dopamine neuronal loss, particularly in the anterior putamen, leads to development of wearing-off in Parkinson's disease.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We studied 342 patients with <I>de novo</I> Parkinson's disease (PD). </LI> <LI> Dopamine neuronal loss in the anterior putamen is a key predictor of wearing-off. </LI> <LI> Putaminal dopamine depletion leads to development of wearing-off in PD. </LI> </UL> </P>
교대근무 간호사의 피로, 신체적 건강상태와 부적 정동에 영향을 미치는 요인
문인오 ( Moon Inn Oh ),이윤주 ( Lee Yoonju ) 부산대학교 여성연구소 2015 여성학연구 Vol.25 No.3
본 연구는 종합병원 교대근무 간호사의 피로, 신체적 건강상태 및 부적 정동 수준을 파악하고 부적 정동에 영향을 미치는 요인을 파악하기 위하여 시행되었다. 연구 대상자는 종합병원에 재직 중인 여성 간호사 187명으로 모두 일반간호사로 교대근무를 하는 자를 대상으로 실시되었다. 인구사회학적 특성과 근무 특성을 포함하여 피로, 신체적 건강상태, 부적 정동을 측정하기 위한 문항이 포함된 자기기입식 설문지(Self-administered questionnaire)를 사용하여 자료수집하였다. 대상자의 특성에 따른 피로, 신체적 건강상태, 부적 정동의 차이는 t-test와 one-way ANOVA로 분석하고 Scheffe test로 사후 검정하였다. 대상자의 피로, 신체적 건강상태와 부적 정동을 부분적 상관분석을 시행하였고, 단계적 회귀분석을 통하여 부적 정동에 영향을 미치는 요인을 확인하였다. 근무부서, 보수 만족도, 수면을 취하기 어려운 근무 유형과 과도한 피로를 느끼는 근무 유형에 따라 피로, 신체적 건강상태와 부적 정동에 차이가 있는 것으로 나타났고 이 요인들을 통제한 가운데 피로(r=.561, p<.001)와 신체적 건강상태(r=.623, p<.001)는 부적 정동과 상관관계가 있는 것으로 확인되었다. 부적 정동에 가장 영향을 미치는 요인은 피로(β=.409, p<.001)로 나타났다. 이는 간호사들이 교대근무로 인한 피로 경험을 반복하게 되면서 부적 정동이 강화될 수 있음을 시사하므로 간호사의 피로를 감소시킬 수 있는 중재 프로그램을 통해 부적 정동을 감소시키고, 장기적으로는 부적 정동에 의한 소진과 이로 인한 이직을 감소하기 위해서 병원, 정부 및 간호단체가 협력하여 다양한 근무제도를 도입할 필요가 있다. The purpose of this study was to define the influencing factors of fatigue, physical health status and negative affectivity in shift-working nurses. Data were collected from 187 shift-working staff nurses who worked in one University hospital with self-reported questionnaires. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA(Scheffe post hoc test) for relationship of participant’s characteristics to fatigue, physical health status and negative affectivity. Partial correlation and stepwise multiple regression was conducted to determine factors influencing negative affectivity. The results showed that working department, pay satisfaction, duty with sleep disturbance and excessive fatigue were associated with fatigue, physical health status and negative affectivity. By controlled these factors, fatigue(r=.561, p<.001) and physical health status(r=.623, p<.001) were partially correlated with negative affectivity. Fatigue(β=.409, p<.001) was significantly associated with negative affectivity and fatigue, physical health status and working department were explained 56.4% of the variance. Results suggested that programs for reduce shift-working nurse’s fatigue are required first. In addition, various working systems need to be considered for preventing negative affectivity due to shift work.
Jang Young Rock,Oh Yoonju,Kim Jin Yong 대한의학회 2024 Journal of Korean medical science Vol.39 No.6
Background: Current guidelines recommend using nirmatrelvir-ritonavir for coronavirus disease 2019 (COVID-19) treatment, but its potential drug interactions and contraindications limit its applicability in certain categories of patients. The aim of the study was to evaluate the real-world effectiveness of molnupiravir and nirmatrelvir-ritonavir in managing COVID-19 among hospitalized patients. Methods: We conducted a retrospective cohort study among hospitalized COVID-19 patients who received molnupiravir or nirmatrelvir-ritonavir and did not require baseline supplemental oxygen from February 2022 to January 2023. We compared the effectiveness of molnupiravir and nirmatrelvir-ritonavir with a focus on disease progression. Results: The study included 401 high-risk, hospitalized adult COVID-19 patients who received molnupiravir or nirmatrelvir-ritonavir. No significant difference was found in disease progression, the composite outcome of disease progression (4.0% vs. 1.4%, P = 0.782), and O2 supplementation via nasal prong (21.8% vs. 14.8%, P = 0.115) between the patients treated with molnupiravir and those treated with nirmatrelvir-ritonavir. This finding was similar after 1:1 propensity-score matching. In the multivariate analysis, molnupiravir treatment was not significantly associated with progression to severe disease. Conclusion: In conclusion, our findings suggest that similar to nirmatrelvir-ritonavir, molnupiravir has a distinct potential role in COVID-19 treatment, transcending its current perceived status as only a secondary option.