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Yebin D. Ahn,Dahyun Yi,Haejung Joung,Eun Hyun Seo,Young Hwa Lee,Min Soo Byun,이준호,So Yeon Jeon,Jun-Young Lee,Bo Kyung Sohn,Dong Young Lee,KBASE Research Group 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.11
Objective The purpose of this study is to identify the demographic variables that are affecting performances on the Logical Memory (LM) subtest included in the Korean version of the Wechsler Memory Scale (WMS)-IV and to provide normative data on the LM subtest for the middle-age and elderly Korean people. Methods The participants were 435 non-demented adults aging from 50 to 90 and with the educational level ranging from 0 to 21 years. Results Age and education were found to be significantly associated with performance on the LM subtest, while gender effect was not statistically significant. Therefore, we stratified the norm blocks by age and education. Age was divided into three groups: 50–59, 60–74, and 75–90 years. Education was stratified into three groups: 0–8 years, 9–12 years, and 13 years or more. Conclusion The normative data provided in the current study are expected to be useful in clinical and research settings to detect or define subtle changes in episodic memory in Korean adults and elderly, and can also be used for cross-cultural comparison of verbal episodic memory performance among elderly populations using different languages.
Psychological Aspects of Child Maltreatment
Ahn, Yebin D.,Jang, Soomin,Shin, Jiyoon,Kim, Jae-Won The Korean Neurosurgical Society 2022 Journal of Korean neurosurgical society Vol.65 No.3
In this review, we provide information about the etiology, risk factors, and clinical presentations of maltreatment to help clinicians better understand child abuse and neglect. Child maltreatment is a major global health challenge that can result in severe consequences. Abused and neglected children are likely to develop psychiatric disorders, such as major depressive disorder, anxiety disorder, and posttraumatic stress disorder. Understanding child maltreatment is expected to prevent and reduce victimization in children, adolescents, and their families.
Psychiatric Manifestation in Patients with Parkinson's Disease
한지원,Yebin D. Ahn,김원석,신철민,정성진,송유성,배윤정,김종민 대한의학회 2018 Journal of Korean medical science Vol.33 No.47
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life — and the need for institutionalization — is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.
Alterations in Social Brain Network Topology at Rest in Children With Autism Spectrum Disorder
Narae Yoon,Youngmin Huh,Hyekyoung Lee,Johanna Inhyang Kim,Jung Lee,Chan-Mo Yang,Soomin Jang,Yebin D. Ahn,Mee Rim Oh,Dong Soo Lee,Hyejin Kang,Bung-Nyun Kim 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.12
Objective Underconnectivity in the resting brain is not consistent in autism spectrum disorder (ASD). However, it is known that the functional connectivity of the default mode network is mainly decreased in childhood ASD. This study investigated the brain network topology as the changes in the connection strength and network efficiency in childhood ASD, including the early developmental stages. Methods In this study, 31 ASD children aged 2–11 years were compared with 31 age and sex-matched children showing typical development. We explored the functional connectivity based on graph filtration by assessing the single linkage distance and global and nodal efficiencies using resting-state functional magnetic resonance imaging. The relationship between functional connectivity and clinical scores was also analyzed. Results Underconnectivities within the posterior default mode network subregions and between the inferior parietal lobule and inferior frontal/superior temporal regions were observed in the ASD group. These areas significantly correlated with the clinical phenotypes. The global, local, and nodal network efficiencies were lower in children with ASD than in those with typical development. In the preschool-age children (2–6 years) with ASD, the anterior-posterior connectivity of the default mode network and cerebellar connectivity were reduced. Conclusion The observed topological reorganization, underconnectivity, and disrupted efficiency in the default mode network subregions and social function-related regions could be significant biomarkers of childhood ASD.