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      • KCI등재

        Ultra-Low Cyclic Fatigue Fracture of Q235B and Q345B Steels and Their Butt Welded Joints

        Xiyue Liu,Yidu Bu,Yuanqing Wang,Yang Guan 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.2

        Earthquake-induced fractures in steel structures are characterised by high-strain low-cycle conditions. In order to investigate the ultra-low cyclic fatigue fracture of steel welded joints under earthquakes, two most commonly used structural steels (Q235B and Q345B) and the corresponding welds were studied by experiments and numerical analysis in this paper. Specimens were extracted from the base material, the weld metal and the heat aff ected zone to investigate the behaviour in diff erent parts of the welded joint. Eighteen smooth round bars were tested under large strain amplitudes, the hysteretic properties, damage degradation characteristics and failure process were analyzed. Constitutive model named Chaboche model was calibrated to describe the cyclic hardening behaviour of these materials. Seventy-two notched round bars with three diff erent notch sizes and two loading protocols were tested to study the fracture behaviour of diff erent materials at different stress triaxialities and diff erent strain amplitudes. Two micromechanical fracture models: cyclic void growth model and degraded signifi cant plastic strain model were calibrated based on the test results. The micromechanical models and Chaboche model were incorporated into numerical simulations by software ABAQUS with subroutine VUMAT to predict the materials fracture. The results show that the failure process under cyclic loads is opposite to that of monotone loads. The dissipation capacity of Q345B is superior to that of Q235B. The fracture resistance deteriorate more in the weld zone under the same loading conditions. The validated models can be used to eff ectively and accurately evaluate the fracture in steel welded connections under ULCF conditions.

      • KCI등재

        Robust, fatigue resistant, self-healing and antifreeze ionic conductive supramolecular hydrogels for wearable flexible sensors

        Jia Yang,Qiong Kang,Bin Zhang,Xiyu Tian,Shuzheng Liu,Gang Qin,Qiang Chen 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.115 No.-

        Ionic conductive hydrogel-based sensors have been capturing growing attention in various areas, but stillcannot satisfy the operating requirements of next generation wearable electronics. Herein, inspired bybiosystems, we demonstrate ionic conductive supramolecular hydrogels with simple one-step methodbased on salting-out effect and multiple hydrogen bond interactions. The supramolecular hydrogels exhibithigh toughness and strength, quick self-recovery, high sensitive sensing performance as well as goodself-healing, fatigue and frost resistances in mechanical and sensing properties, and can monitor largeand subtle movements and physiological activities of the human body sensitively, quickly and stably. Thus, it provides a convenient and promising way to obtain stretchable sensors of excellent comprehensiveproperties, which have tremendous application potential as wearable electronic devices in harshenvironments.

      • KCI등재

        Novel artesunate-metformin conjugate inhibits bladder cancer cell growth associated with Clusterin/SREBP1/FASN signaling pathway

        Lin Peiyu,Yang Xiyue,Wang Linghui,Zou Xin,Mu Lingli,Xu Cangcang,Yang Xiaoping 대한약리학회 2024 The Korean Journal of Physiology & Pharmacology Vol.28 No.3

        Bladder cancer remains the 10th most common cancer worldwide. In recent years, metformin has been found to have potential anti-bladder cancer activity while high concentration of IC50 at millimolar level is needed, which could not be reached by regular oral administration route. Thus, higher efficient agent is urgently demanded for clinically treating bladder cancer. Here, by conjugating artesunate to metformin, a novel artesunate-metformin dimer triazine derivative AM2 was designed and synthesized. The inhibitory effect of AM2 on bladder cancer cell line T24 and the mechanism underlying was determined. Anti-tumor activity of AM2 was assessed by MTT, cloning formation and wound healing assays. Decreasing effect of AM2 on lipogenesis was determined by oil red O staining. The protein expressions of Clusterin, SREBP1 and FASN in T24 cells were evaluated by Western blotting. The results show that AM2 significantly inhibited cell proliferation and migration at micromolar level, much higher than parental metformin. AM2 reduced lipogenesis and down-regulated the expressions of Clusterin, SREBP1 and FASN. These results suggest that AM2 inhibits the growth of bladder cancer cells T24 by inhibiting cellular lipogenesis associated with the Clusterin/SREBP1/FASN signaling pathway.

      • KCI등재

        Efficient Method to Include Joint Zones of Chord Members in Finite Element Model of Tubular Transmission Tower at Linear Elastic Stage

        Haifeng Liu,Junke Han,Zhenmao Sun,Jingbo Yang,Fengli Yang,Xiyu Xu 한국강구조학회 2015 International Journal of Steel Structures Vol.15 No.4

        To include the effects of the joint zones efficiently, firstly a chord member considering the joint zones is seen as a combination of three beams with different sections and its element stiffness matrix is derived; Secondly, based on the statistically geometrical properties of the joint zones and chord members in service, the coefficients in the element stiffness matrix of the varied section beam element related to the moments and shear forces greatly increase more than 70%, while the coefficients related to axial forces only increase less than 2%. Therefore, along with the other two inherent mechanical properties of member structures, it is essential to include the effects of the joint zones. Finally, the results by the finite element models where the chord members and the joint zones are simulated by four methods are compared, which proves the efficiency and the accuracy of the varied section beam element.

      • KCI등재

        SiC IGBT degradation mechanism investigation under HV‑H3TRB tests

        Ziming Wu,Zongbei Dai,Jian Zhou,Huafeng Dong,Wencan Wang,Feiwan Xie,Haoran Wang,Jiahui Yan,Xiyu Chen,Shaohua Yang,Fugen Wu 전력전자학회 2024 JOURNAL OF POWER ELECTRONICS Vol.24 No.2

        The high voltage-high humidity-high temperature reverse bias (HV-H3TRB) test was utilized to evaluate the reliability of silicon carbide insulated gate bipolar transistors (SiC IGBTs). Moisture invasion often induces termination/passivation and metal corrosion. Therefore, the HV-H3TRB test is generally used to assess termination / passivation robustness. However, under the HV-H3TRB test conditions, gate quality degradation may occur. In this study, the dominant degradation mechanism of SiC IGBTs was investigated. The changes of the most sensitive static characteristics (e.g., threshold voltage, breakdown voltage, and leakage current) were recorded. The threshold voltage decreased and leakage current increased substantially after > 1000 h of HV-H3TRB tests under 85 ℃/85% RH climate conditions. Capacitance-voltage (C-V) curve measurements indicated that the mobile ions at the SiC/SiO2 interface or in the gate oxide likely caused the threshold-voltage instability in the SiC IGBTs after the HV-H3TRB tests. This instability can be recovered by applying a negative gate bias. Subsequent failure analysis confirmed no corrosion of metals or termination/passivation in the device, which indicates the robustness of the passivation (consisting of phosphor-silicate glass and Si3N4). Therefore, the gate quality appears to be a significant reliability risk for SiC IGBTs under high humidity, high temperature, and high voltage conditions.

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