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      • KCI등재후보

        Correlations Between Fasciology and Yin Yang Doctrine

        Hui Tao,Mei-chun Yu,Hui-ying Yang,Rong-mei Qu,Chun Yang,Xin Zhou,Yu Bai,Jing-peng Wu,Jun Wang,Ou Sha,Lin Yuan 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.2

        The aim of this study is to explore the correlations between fasciology and yin yang doctrine. Professor Yuan developed fasciology by three-dimensional reconstruction of connective tissue (fascia) in the trunk and limbs of the human body and tracing back to tissue origins in light of biological evolution and developmental biology. Fasciology states that the human body can be divided into two systems: the supporting-storing system and the functional system. This article elaborates on the roles of the two systems and their mutual relationship. The two systems are used to analyze the yin,the yang, and their relationship. The two systems are promoted but also restricted in different contexts. The supporting-storing system is formed by undifferentiated connective tissue and provides undifferentiated cells and nutrients for differentiated cells of the functional system. Thus, the supporting-storing system could be classified as quiet, similar to yin. The functional system continuously maintains the various functional activities of the human body. Thus, the functional system could be classified as active, similar to yang. In interpreting the yin yang doctrine from the point of view of fasciology, yin can be compared with the supporting-storing system and yang can be compared with the functional system.

      • KCI등재

        Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging

        Huan-Huan Chen,Hao Hu,Wen Chen,Dai Cui,Xiao-Quan Xu,Fei-Yun Wu,Tao Yang 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.3

        Objective: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients with thyroidassociated orbitopathy (TAO) as well as in evaluating disease activity. Materials and Methods: We enrolled 35 TAO patients and 22 healthy controls (HCs) who underwent pre-treatment rs-EPIbased DTI. Mean, axial, and radial diffusivity (MD, AD, and RD) and fractional anisotropy (FA) of the medial and lateral EOMs and optic nerve for each orbit were calculated and compared between TAO and HC groups and between active and inactive TAO groups. Factors such as age, sex, disease duration, mediation, and smoking history between groups were also compared. Logistic regression analysis was used to evaluate the predictive value of significant variables for disease activity. Results: Disease duration was significantly shorter in active TAOs than in inactive ones (p < 0.001). TAO patients showed significantly lower FA and higher MD, AD, and RD than HCs for both medial and lateral EOMs (p < 0.001), but not the AD value of lateral EOMs (p = 0.619). Active patients had significantly higher FA, MD, and AD than inactive patients for medial EOMs (p < 0.005), whereas only FA differed significantly in the lateral EOMs (p = 0.018). The MD, AD, and RD of optic nerves were significantly lower in TAO patients than HCs (p < 0.05), except for FA (p = 0.129). Multivariate analysis showed that the MD of medial EOMs and disease duration were significant predictors for disease activity. The combination of these two parameters showed optimal diagnostic efficiency for disease activity (area under the curve, 0.855; sensitivity, 68.4%; specificity, 96.9%). Conclusion: rs-EPI-based DTI is promising in assessing microstructural changes of EOMs and optic nerves and can help to indicate the disease activity of TAO, especially through the MD of medial EOMs.

      • Reliability Analysis and Prediction for Product Design Based on Feature Similarity

        Tao Yang,Yu Yang,Yao Jiao 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.5

        During product design phase, aiming at the problem of lacking reliability data, lower of product reliability, feature similarity-based new product design reliability analysis and prediction model were proposed. Putting the new product features as an evaluation objectives, an approach named Technique for Order Preference by Similarity to Ideal Solution(TOPSIS) was established firstly for selecting similar features products; Then, in order to realize the reliability analysis relational mapping with the new product design, the failure structure of the similar features products was quantified and the product failure structure matrix (FSM) was established, respectively; Afterwards, the Group Decision Making Method (GDMM) was presented for determining the improvement factor of the similar features products failure causes, on that basis, the new product features failure structure was generated to predict the reliability of new designing products. Finally, feasibility and effectiveness of the model were verified through an example of new Smart Mobile Phone product design.

      • Chaotic secure communication systems : History and new results

        Tao Yang 에스케이텔레콤 (주) 1999 Telecommunications Review Vol.9 No.4

        Secure communication using synchronization between chaotic systems(chaotic secure communication, for short) is a new concept of secure communication. The great potentials of this kind of ''hardware key'' secure communication systems had driven the progress of this field rapidly. Since 1992, chaotic secure communication has evolved four generations. In this paper, a detailed history of chaotic secure communication systems is given. The disadvantage of the first three generations of chaotic secure communication schemes is low efficiency of channel usage. To overcome this disadvantage, a chaotic communication scheme, which belongs to the fourth generation, using impulsive synchronization of chaotic systems is presented. In this paper, impulsive synchronization of two chaotic systems is reformulated as impulsive stabilization of a synchronization error system to the origin. Based on the theory of impulsive differential equations, we present theoretical results on the asymptotic synchronization of two chaotic systems by using synchronization impulses. An estimate of the upper bound of impulse interval is given for the purpose of asymptotic synchronization. The robustness of impulsive synchronization to additive channel noise and parameter mismatch is also studied. We conclude that impulsive synchronization is robuster than continuous synchronization. Combining both conventional cryptographic method and impulsive synchronization of chaotic systems, we propose a new chaotic secure communication scheme. We use this new chaotic secure communication scheme to transmit a speech signal. Computer simulation results based on Chua's oscillators are given.

      • Expression of PGDH Correlates with Cell Growth in Both Esophageal Squamous Cell Carcinoma and Adenocarcinoma

        Yang, Guo-Tao,Wang, Juan,Xu, Tong-Zhen,Sun, Xue-Fei,Luan, Zi-Ying Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

        Esophageal cancer represents the fourth most common gastrointestinal cancer and generally confers a poor prognosis. Prostaglandin-producing cyclo-oxygenase has been implicated in the pathogenesis of esophageal cancer growth. Here we report that prostaglandin dehydrogenase, the major enzyme responsible for prostaglandin degradation, is significantly reduced in expression in esophageal cancer in comparison to normal esophageal tissue. Reconstitution of PGDH expression in esophageal cancer cells suppresses cancer cell growth, at least in part through preventing cell proliferation and promoting cell apoptosis. The tumor suppressive role of PGDH applies equally to both squamous cell carcinoma and adenocarcinoma, which enriches our understanding of the pathogenesis of esophageal cancer and may provide an important therapeutic target.

      • Nitric oxide synthase inhibitors: a review of patents from 2011 to the present

        Yang, Yanyan,Yu, Tao,Lian, Yu-ji,Ma, Rujun,Yang, Sungjae,Cho, Jae Youl Informa UK, Ltd. 2015 Expert opinion on therapeutic patents Vol.25 No.1

        <P><B><I>Introduction:</I></B> Nitric oxide synthases (NOSs) are a family of enzymes that play an essential role in synthesizing nitric oxide (NO) by oxidizing <SMALL>L</SMALL>-arginine. As previously reported, NO is a significant mediator in cellular signaling pathways. It serves as a crucial regulator in insulin secretion, vascular tone, peristalsis, angiogenesis, neural development and inflammation. Due to its important role, the inhibition of these vital enzymes provides, as tools, the opportunity to gain an insight into potential therapeutic applications targeting NOSs.</P><P><B><I>Areas covered:</I></B> This paper reviews the patent literature between 2011 and mid-2014 that specified inhibitors of NOS family members as the significant targets. Google and Baidu search engines were used to find relevant patents and clinical information using NOSs or NOS inhibitor as search terms.</P><P><B><I>Expert opinion:</I></B> Considerable recent progress has been made in the development of NOS inhibitors with pharmacodynamic and pharmacokinetic properties, and such development is likely to continue. The patented compounds attenuated mostly embodying evidence from <I>in vitro</I> and <I>in vivo</I> trials that demonstrate good potential for future clinical human trials and industrial applications. Furthermore, new techniques such as X-ray ligand crystallographic study and structure-activity relationship were popularly utilized, which give new insights for developing novel, safe, efficient and selective NOS inhibitors.</P>

      • KCI등재

        Optimal User Density and Power Allocation for Device-to-Device Communication Underlaying Cellular Networks

        ( Yang Yang ),( Ziyang Liu ),( Boao Min ),( Tao Peng ),( Wenbo Wang ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.2

        This paper analyzes the optimal user density and power allocation for Device-to-Device (D2D) communication underlaying cellular networks on multiple bands with the target of maximizing the D2D transmission capacity. The entire network is modeled by Poisson point process (PPP) which based on stochastic geometry. Then in order to ensure the outage probabilities of both cellular and D2D communication, a sum capacity optimization problem for D2D system on multiple bands is proposed. Using convex optimization, the optimal D2D density is obtained in closed-form when the D2D transmission power is determined. Next the optimal D2D transmission power is obtained in closed-form when the D2D density is fixed. Based on the former two conclusions, an iterative algorithm for the optimal D2D density and power allocation on multiple bands is proposed. Finally, the simulation results not only demonstrate the D2D performance, density and power on each band are constrained by cellular communication as well as the interference of the entire system, but also verifies the superiority of the proposed algorithm over sorting-based and removal algorithms.

      • Stimulation of Osteogenic Differentiation in Stromal Cells of Giant Cell Tumour of Bone by Zoledronic Acid

        Yang, Tao,Zheng, Xiao-Fei,Li, Mei,Lin, Xi,Yin, Qing-Shui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

        Therapeutic effects of zoledronic acid (ZOL) on giant cell tumour of bone (GCT) have been proven. Apoptosis induction was considered to be one of the mechanisms of ZOL tumour inhibition. In this study, we presented the possibility of an osteogenic differentiation stimulation mechanism of ZOL and further investigated dosage and time effects. We treated stromal cells of GCT (GCTSC) with ZOL for 48 hours at different concentrations ($0{\mu}M$, $0.01{\mu}M$, $0.1{\mu}M$, $1{\mu}M$, 5${\mu}M$, $30{\mu}M$) and assessed apoptotic and osteogenic differentiation markers with immunohistochemical techniques and real-time quantitative RT-PCR. Our results suggested that ZOL enhanced mRNA expression of Cbfa-1, osterix and osteocalcin genes with a maximum effect at $1{\mu}M$ in GCTSC. Time course experiments indicated a time dependent osteogenic differentiation effect. In conclusion, ZOL may be considered as an adjuvant in the treatment of GCT not only by inducing apoptosis but also by stimulating osteogenic differentiation of remaining tumor stromal cells after surgery.

      • Channel-Independent Chaotic Secure Communication Using General Chaotic Synchronization

        Tao Yang,S. M. Shahruz 에스케이텔레콤 (주) 1997 Telecommunications Review Vol.7 No.2

        In this paper, the generalized synchronization (GS) of two identical chaotic systems through a channel with unknown channel characteristics, is studied. First, theoretical results providing conditions for the GS with unknown channel characteristics are presented. Then, the GS transformation for linear case, which is invertible, is given. Examples of the GS through nonlinear static and dynamic channels are also given. It is shown that the GS schemes can be used in chaotic secure communication which is channel independent. Here, channel independence means that the proposed chaotic secure communication scheme can work under different unknown channel conditions. Simulation results using Chua's circuit and the Lorenz system are presented.

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